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Silence Therapeutics plc

$13.06 +$6.91 (+112.36%)
NASDAQ · 14 Sep 2026 20:00 UTC
Previous Close
$13.02
Day Range
$12.72$13.27
Year Range
$4.19$17.58
Market Cap
616.88M
AVG Volume
788.53K
Trailing/Forward PE
-3.43/-
PEG ratio
-0.17
Dividend Yield
-
Next Earnings Date
2026-11-05
Primary Exchange
NASDAQUS
Revenue (USD) · TTM
020M40M60M24 Q124 Q224 Q324 Q425 Q125 Q225 Q325 Q426 Q126 Q2
SLN Revenue (USD) · TTM by quarter
PeriodRevenue (USD) · TTM
26 Q2614.29K
26 Q1921.49K
25 Q4683.9K
25 Q324.98M
25 Q225.96M
25 Q126.25M
24 Q441.77M
24 Q319.54M
24 Q221.19M
24 Q129.7M
Net Income (USD) · TTM
-150M-100M-50M024 Q124 Q224 Q324 Q425 Q125 Q225 Q325 Q426 Q126 Q2
SLN Net Income (USD) · TTM by quarter
PeriodNet Income (USD) · TTM
26 Q2-59.95M
26 Q1-85.17M
25 Q4-107.15M
25 Q3-81.21M
25 Q2-87.26M
25 Q1-65.31M
24 Q4-30.71M
24 Q3-59.3M
24 Q2-40.54M
24 Q1-35.38M
Operating Income (USD) · TTM
-150M-100M-50M024 Q124 Q224 Q324 Q425 Q125 Q225 Q325 Q426 Q126 Q2
SLN Operating Income (USD) · TTM by quarter
PeriodOperating Income (USD) · TTM
26 Q2-66.84M
26 Q1-86.59M
25 Q4-108.32M
25 Q3-98.94M
25 Q2-95.23M
25 Q1-80.69M
24 Q4-49.52M
24 Q3-59.74M
24 Q2-49.9M
24 Q1-43.04M
EBITDA (USD) · TTM
-150M-100M-50M024 Q124 Q224 Q324 Q425 Q125 Q225 Q325 Q426 Q126 Q2
SLN EBITDA (USD) · TTM by quarter
PeriodEBITDA (USD) · TTM
26 Q2-60.29M
26 Q1-78.13M
25 Q4-100.03M
25 Q3-81.18M
25 Q2-81.82M
25 Q1-68.12M
24 Q4-34.32M
24 Q3-56.42M
24 Q2-45.51M
24 Q1-39.37M
Cash Flows (USD) · TTM
-80M-60M-40M-20M024 Q124 Q224 Q324 Q425 Q125 Q225 Q325 Q426 Q126 Q2
SLN Cash Flows (USD) · TTM by quarter
PeriodCash Flows (USD) · TTM
26 Q2-42.34M
26 Q1-65.67M
25 Q4-62.38M
25 Q3-69.96M
25 Q2-78.77M
25 Q1-62.43M
24 Q4-59.26M
24 Q3-46.21M
24 Q2-31.4M
24 Q1-40.85M
EPS (USD) · TTM
-8-6-4-2024 Q124 Q224 Q324 Q425 Q125 Q225 Q325 Q426 Q126 Q2
SLN EPS (USD) · TTM by quarter
PeriodEPS (USD) · TTM
26 Q2-3.81
26 Q1-5.43
25 Q4-6.81
25 Q3-5.16
25 Q2-5.55
25 Q1-4.14
24 Q4-1.96
24 Q3-3.94
24 Q2-2.89
24 Q1-2.77
Expenses (USD) · TTM
050M100M150MR&DSG&ACapex24 Q124 Q224 Q324 Q425 Q125 Q225 Q325 Q426 Q126 Q2
SLN Expenses (USD) · TTM by quarter
PeriodExpenses (USD) · TTM
26 Q267.25M
26 Q185.54M
25 Q4107.04M
25 Q3120.35M
25 Q2114.97M
25 Q1100.05M
24 Q481.66M
24 Q369.86M
24 Q262.81M
24 Q164.17M
Shares Outstanding · TTM
-15M-10M-5M024 Q124 Q224 Q324 Q425 Q125 Q225 Q325 Q426 Q126 Q2
SLN Shares Outstanding · TTM by quarter
PeriodShares Outstanding · TTM
26 Q2-13.56M
26 Q1-14.34M
25 Q4-14.63M
25 Q3-10.78M
25 Q2-11.34M
25 Q1-13.4M
24 Q4-14.78M
24 Q3-12.86M
24 Q2-13.62M
24 Q1-12.47M
Employee Count
050100150202020212022202320242025
SLN Employee Count by quarter
PeriodEmployee Count
202588
2024116
2023109
2022122
2021105
202074
Free Cash Flow Yield
-200%-150%-100%-50%0%med -68.43%Dec 24Apr 25Jul 25Nov 25Feb 26Jun 26Sep 26
SLN Free Cash Flow Yield by quarter
PeriodFree Cash Flow Yield
Sep 26-20.59%
Sep 26-20.66%
Sep 26-18.43%
Aug 26-20.04%
Aug 26-20.27%
Aug 26-19.6%
Aug 26-34.9%
Jul 26-39.76%
Jul 26-37.85%
Jul 26-39.72%
Jul 26-45.89%
Jul 26-40.14%
Jun 26-41.13%
Jun 26-60.19%
Jun 26-62.35%
Jun 26-67.6%
May 26-60.45%
May 26-67.27%
May 26-68.38%
May 26-59.84%
May 26-55.57%
Apr 26-51.46%
Apr 26-52.62%
Apr 26-69.15%
Apr 26-66.7%
Mar 26-80.37%
Mar 26-64.21%
Mar 26-57.42%
Mar 26-63.6%
Feb 26-81.68%
Feb 26-88.87%
Feb 26-99.85%
Feb 26-93.54%
Jan 26-92.19%
Jan 26-78.37%
Jan 26-88.16%
Jan 26-80.5%
Jan 26-72.25%
Dec 25-71.67%
Dec 25-69.75%
Dec 25-70.31%
Dec 25-63.84%
Nov 25-65.93%
Nov 25-70.42%
Nov 25-65.06%
Nov 25-67.53%
Oct 25-69.88%
Oct 25-68.54%
Oct 25-76.97%
Oct 25-100.06%
Oct 25-100.06%
Sep 25-90.31%
Sep 25-102.31%
Sep 25-110.94%
Sep 25-87.93%
Aug 25-104.02%
Aug 25-93.52%
Aug 25-91.13%
Aug 25-99.27%
Aug 25-64.28%
Jul 25-62.55%
Jul 25-65.66%
Jul 25-61.58%
Jul 25-71.85%
Jun 25-68.5%
Jun 25-66.65%
Jun 25-74.41%
Jun 25-72.9%
May 25-67.91%
May 25-78.38%
May 25-90.75%
May 25-107.19%
May 25-128.65%
Apr 25-150.98%
Apr 25-160.98%
Apr 25-194.01%
Apr 25-188.19%
Mar 25-143.18%
Mar 25-138.22%
Mar 25-126.08%
Mar 25-101.52%
Feb 25-106.5%
Feb 25-77.65%
Feb 25-76.6%
Feb 25-72.91%
Jan 25-68.48%
Jan 25-64.61%
Jan 25-70.01%
Jan 25-60.04%
Jan 25-49.51%
Dec 24-52.19%
Dec 24-53.78%
Dec 24-57.63%
Dec 24-44.05%
Nov 24-47.37%
Nov 24-52.65%
Nov 24-29.27%
Nov 24-14.86%
Nov 24-14.73%
Oct 24-14.45%
Price to Sales
0100200300400med 3.94Dec 24Apr 25Jul 25Nov 25Feb 26Jun 26Sep 26
SLN Price to Sales by quarter
PeriodPrice to Sales
Sep 26334.75
Sep 26333.73
Sep 26373.97
Aug 26343.98
Aug 26340.14
Aug 26351.67
Aug 26204.18
Jul 26179.23
Jul 26188.29
Jul 26179.4
Jul 26155.31
Jul 26177.53
Jun 26173.25
Jun 26118.41
Jun 26114.31
Jun 26105.42
May 26117.89
May 26105.93
May 26104.23
May 26119.09
May 26164.14
Apr 26177.27
Apr 26173.35
Apr 26131.91
Apr 26136.75
Mar 26113.5
Mar 26142.04
Mar 26158.85
Mar 26143.43
Feb 263.43
Feb 263.15
Feb 262.81
Feb 262.99
Jan 263.04
Jan 263.57
Jan 263.18
Jan 263.48
Jan 263.88
Dec 253.91
Dec 254.02
Dec 253.98
Dec 254.39
Nov 254.25
Nov 253.98
Nov 254.31
Nov 254.15
Oct 254.34
Oct 254.43
Oct 253.94
Oct 253.03
Oct 253.03
Sep 253.36
Sep 252.97
Sep 252.74
Sep 253.45
Aug 252.92
Aug 253.24
Aug 253.33
Aug 253.06
Aug 253.7
Jul 253.8
Jul 253.62
Jul 253.86
Jul 253.31
Jun 253.47
Jun 253.57
Jun 253.2
Jun 253.26
May 253.5
May 253.03
May 252.62
May 252.22
May 251.1
Apr 250.94
Apr 250.88
Apr 250.73
Apr 250.75
Mar 250.99
Mar 251.03
Mar 251.13
Mar 251.4
Feb 251.33
Feb 253.05
Feb 253.09
Feb 253.24
Jan 253.45
Jan 253.66
Jan 253.38
Jan 253.94
Jan 254.78
Dec 244.53
Dec 244.4
Dec 244.1
Dec 245.37
Nov 244.99
Nov 244.49
Nov 248.08
Nov 249.97
Nov 2410.06
Oct 2410.25
Price/Operating Cashflow
02505007501000med 120.74Nov 20Jan 21Sep 21Dec 21Mar 22Jun 22Aug 22
SLN Price/Operating Cashflow by quarter
PeriodPrice/Operating Cashflow
Aug 2219.9
Aug 2217.58
Aug 2217.83
Aug 2218.25
Jul 2218.47
Jul 2218.37
Jul 2220.65
Jul 2220.84
Jul 2221.87
Jun 2221.36
Jun 2216.21
Jun 2215.62
Jun 2216.23
May 2234.14
May 2229.45
May 2235.19
May 2243.1
Apr 2242.13
Apr 2253.65
Apr 2256.96
Apr 2258.48
Apr 2264.78
Mar 2263.59
Mar 2255.78
Mar 22106.33
Mar 22106.76
Feb 22113.23
Feb 22115.95
Feb 22139.2
Feb 22129.99
Jan 22120.74
Jan 22122.17
Jan 22131.25
Jan 22142.88
Dec 21146.5
Dec 21144.79
Dec 21149.1
Dec 21154.57
Dec 21161.2
Nov 21211.94
Nov 21219.35
Nov 21217.46
Nov 21217.85
Oct 21206.22
Oct 21214.79
Oct 21203.98
Oct 21198.92
Oct 21195.52
Sep 21204.76
Sep 21202.61
Sep 21208.4
Sep 21213.7
Mar 21757.85
Mar 21745.55
Mar 21792.09
Mar 21739.99
Feb 21807.05
Feb 21863.92
Feb 21818.86
Feb 21788
Jan 21811.91
Jan 21786.55
Jan 21720.48
Jan 21767.72
Dec 20716.45
Dec 20656.91
Dec 20624.89
Dec 20645.66
Dec 20571.23
Nov 2027.55
Nov 2026.35
Nov 2031.76
Nov 2025.13
Oct 2024.29
Oct 2024.92
Oct 2025.18
Oct 2026.38
Oct 2027.36
Sep 2028.8
Sep 2030.03
Sep 2031.95
Price to Book
0246med 1.34Sep 24Jan 25Apr 25Nov 25Feb 26Jun 26Sep 26
SLN Price to Book by quarter
PeriodPrice to Book
Sep 265.35
Sep 265.33
Sep 265.97
Aug 265.49
Aug 265.43
Aug 265.62
Aug 263.81
Jul 263.34
Jul 263.51
Jul 263.35
Jul 262.9
Jul 263.31
Jun 263.23
Jun 262.21
Jun 262.13
Jun 261.97
May 262.2
May 261.98
May 261.94
May 262.22
May 261.8
Apr 261.95
Apr 261.9
Apr 261.45
Apr 261.5
Mar 261.25
Mar 261.56
Mar 261.74
Mar 261.57
Feb 261.16
Feb 261.06
Feb 260.95
Feb 261.01
Jan 261.02
Jan 261.21
Jan 261.07
Jan 261.17
Jan 261.31
Dec 251.32
Dec 251.35
Dec 251.34
Dec 251.48
Nov 251.43
Nov 251.34
Nov 251.45
Nov 251.4
Oct 251.2
Oct 251.22
Oct 251.09
Oct 250.84
Oct 250.84
Sep 250.93
Sep 250.82
Sep 250.75
Sep 250.95
Aug 250.8
Aug 250.89
Aug 250.92
Aug 250.84
May 250.43
Apr 250.37
Apr 250.34
Apr 250.29
Apr 250.29
Mar 250.39
Mar 250.4
Mar 250.44
Mar 250.55
Feb 250.52
Feb 250.63
Feb 250.64
Feb 250.67
Jan 250.71
Jan 250.76
Jan 250.7
Jan 250.81
Jan 250.99
Dec 240.94
Dec 240.91
Dec 240.85
Dec 241.11
Nov 241.03
Nov 240.93
Nov 241.67
Nov 241.88
Nov 241.89
Oct 241.93
Oct 241.91
Oct 242.08
Oct 241.97
Sep 241.89
Sep 241.9
Sep 241.97
Sep 241.97
Aug 242.01
Aug 241.7
Aug 241.68
Aug 241.21
Aug 241.38
Jul 241.53
Silence Therapeutics plc
SLN
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News: SLN

Silence Therapeutics Announces Closing of Upsized Public Offering and Full Exercise of Underwriters' Option to Purchase Additional ADSs

businesswire.com · 14 Aug 2026

Silence Therapeutics Announces Closing of Upsized Public Offering and Full Exercise of Underwriters' Option to Purchase Additional ADSs

LONDON--(BUSINESS WIRE)---- $SLN #SenseofSilence--Silence Therapeutics plc, (Nasdaq: SLN), (“Silence” or the “Company”), a global clinical-stage biotechnology company developing novel short interfering RNA (“siRNA”) therapies, today announced the closing of its previously announced underwritten public offering of 14,907,407 American Depositary Shares (“ADSs”), each representing three ordinary shares of £0.05 each in the capital of the Company, in the United States at a public offering price of $13.50 per ADS, which inc.

Wall Street Analysts Predict a 140.06% Upside in Silence Therapeutics (SLN): Here's What You Should Know

zacks.com · 13 Aug 2026

Wall Street Analysts Predict a 140.06% Upside in Silence Therapeutics (SLN): Here's What You Should Know

The average of price targets set by Wall Street analysts indicates a potential upside of 140.1% in Silence Therapeutics (SLN). While the effectiveness of this highly sought-after metric is questionable, the positive trend in earnings estimate revisions might translate into an upside in the stock.

Silence Therapeutics Announces Pricing of Upsized $175 Million Underwritten Public Offering

businesswire.com · 11 Aug 2026

Silence Therapeutics Announces Pricing of Upsized $175 Million Underwritten Public Offering

LONDON--(BUSINESS WIRE)---- $SLN #SenseofSilence--Silence Therapeutics plc (“Silence” or the “Company”) , a global clinical-stage biotechnology company developing novel short interfering RNA (“siRNA”) therapies, today announced that it has priced its previously announced underwritten public offering of 12,962,963 American Depositary Shares (“ADSs”), each representing three ordinary shares of £0.05 each in the capital of the Company, in the United States at a public offering price of $13.50 per ADS. In addition, Silence.

Silence Therapeutics’ Divesiran Hits Phase II Goal, Sets Up Phase III PV Trial

defenseworld.net · 11 Aug 2026

Silence Therapeutics’ Divesiran Hits Phase II Goal, Sets Up Phase III PV Trial

Silence Therapeutics (NASDAQ: SLN) reported top-line results from its Phase II SANRECO trial of divesiran in patients with phlebotomy-dependent polycythemia vera, or PV, with the study meeting its primary endpoint and supporting the company's plan to advance a quarterly dosing regimen into Phase III. PV is a rare myeloproliferative neoplasm in which elevated hematocrit levels can

Silence Therapeutics' Divesiran Hits Phase II Goal, Sets Up Phase III PV Trial

marketbeat.com · 11 Aug 2026

Silence Therapeutics' Divesiran Hits Phase II Goal, Sets Up Phase III PV Trial

Silence Therapeutics NASDAQ: SLN reported top-line results from its Phase II SANRECO trial of divesiran in patients with phlebotomy-dependent polycythemia vera, or PV, with the study meeting its primary endpoint and supporting the company's plan to advance a quarterly dosing regimen into Phase III.

Silence Therapeutics plc (SLN) Discusses Top-Line Results From SANRECO Phase II Trial of Divesiran in Polycythemia Vera Transcript

seekingalpha.com · 10 Aug 2026

Silence Therapeutics plc (SLN) Discusses Top-Line Results From SANRECO Phase II Trial of Divesiran in Polycythemia Vera Transcript

Silence Therapeutics plc (SLN) Discusses Top-Line Results From SANRECO Phase II Trial of Divesiran in Polycythemia Vera Transcript

Silence Therapeutics Announces Proposed Public Offering of $150 Million of American Depositary Shares

businesswire.com · 10 Aug 2026

Silence Therapeutics Announces Proposed Public Offering of $150 Million of American Depositary Shares

LONDON--(BUSINESS WIRE)---- $SLN #SenseofSilence--Silence Therapeutics plc (“Silence” or the “Company”), a global clinical-stage biotechnology company developing novel short interfering RNA (“siRNA”) therapies, today announced that it has commenced an underwritten public offering of approximately $150 million of its American Depositary Shares (“ADSs”), each representing three ordinary shares of £0.05 each in the capital of the Company, in the United States. The proposed offering is a public offering registered under th.

Silence Therapeutics Says Blood Cancer Trial Delivers 'Best-Case Outcome'

benzinga.com · 10 Aug 2026

Silence Therapeutics Says Blood Cancer Trial Delivers 'Best-Case Outcome'

Silence Therapeutics plc (NASDAQ:SLN) stock is trading higher on Monday after the company reported positive topline outcomes from its Phase 2 SANRECO study assessing divesiran for polycythemia vera. It is a rare, slow-growing blood cancer where the bone marrow makes too many red blood cells.

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