AI Analysis

Log in to generate an AI summary for this stock.

Log in to generate a MOAT report for this stock.

Log in to generate an earnings report for this stock.

Log in to generate an operating leverage report for this stock.

Log in to generate a management report for this stock.

Log in to generate a valuation report for this stock.

Silence Therapeutics plc

$13.06 +$6.91 (+112.36%)
NASDAQ · 14 Sep 2026 20:00 UTC
Previous Close
$13.02
Day Range
$12.72$13.27
Year Range
$4.19$17.58
Market Cap
616.88M
AVG Volume
788.53K
Trailing/Forward PE
-3.43/-
PEG ratio
-0.17
Dividend Yield
-
Next Earnings Date
2026-11-05
Primary Exchange
NASDAQUS
Revenue (USD)
020M40M60M2016201720182019202020212022202320242025
SLN Revenue (USD) by year
PeriodRevenue (USD)
2025683.9K
202441.77M
202325.38M
202217.5M
202112.41M
20205.48M
2019244K
20180
201716K
2016770K
Net Income (USD)
-150M-100M-50M02016201720182019202020212022202320242025
SLN Net Income (USD) by year
PeriodNet Income (USD)
2025-107.15M
2024-30.71M
2023-43.27M
2022-40.49M
2021-39.41M
2020-32.55M
2019-19.58M
2018-18.41M
2017-1.62M
2016-8.44M
Operating Income (USD)
-150M-100M-50M02016201720182019202020212022202320242025
SLN Operating Income (USD) by year
PeriodOperating Income (USD)
2025-108.32M
2024-49.52M
2023-49.6M
2022-48.59M
2021-45.81M
2020-35.85M
2019-22.73M
2018-20.57M
2017-14.39M
2016-11.91M
EBITDA (USD)
-150M-100M-50M02016201720182019202020212022202320242025
SLN EBITDA (USD) by year
PeriodEBITDA (USD)
2025-100.03M
2024-34.32M
2023-48.11M
2022-46.84M
2021-44.91M
2020-30.52M
2019-22.25M
2018-20.17M
2017-13.96M
2016-11.6M
Cash Flows (USD)
-80M-60M-40M-20M020M2016201720182019202020212022202320242025
SLN Cash Flows (USD) by year
PeriodCash Flows (USD)
2025-62.38M
2024-59.26M
2023-39.4M
2022-45.84M
20215.47M
2020-11.29M
20191.72M
2018-16.89M
2017-9.77M
2016-10.56M
EPS (USD)
-8-6-4-202016201720182019202020212022202320242025
SLN EPS (USD) by year
PeriodEPS (USD)
2025-6.81
2024-1.96
2023-3.45
2022-3.78
2021-1.34
2020-1.17
2019-0.78
2018-0.8
2017-0.07
2016-0.36
Expenses (USD)
050M100M150MR&DSG&ACapex2016201720182019202020212022202320242025
SLN Expenses (USD) by year
PeriodExpenses (USD)
2025107.04M
202481.66M
202364.71M
202255.65M
202152.11M
202038.5M
201922.99M
201820.7M
201714.58M
201613.17M
Cash & Debt (USD)
050M100M150M2016201720182019202020212022202320242025
SLN Cash & Debt (USD) by year
PeriodCash & Debt (USD)
202585.11M
2024117.73M
202368.79M
202271.14M
202173.54M
202037.45M
201933.52M
201826.54M
201743.06M
201639.01M
Debt ratios
00.20.40.60.820182019202020212022202320242025
SLN Debt ratios by year
PeriodDebt ratios
20250.37
20240.68
20230.4
20220.49
20210.62
20200.43
20190.49
20180.48
Margins
-60000%-40000%-20000%0%20000%201620172019202020212022202320242025
SLN Margins by year
PeriodMargins
202561.63%
202476.49%
202359.34%
202237.83%
202139.94%
202031.34%
2019-4042.62%
2017-49543.75%
2016-1031.3%
Return on Capital
-600%-400%-200%0%2016201720182019202020212022202320242025
SLN Return on Capital by year
PeriodReturn on Capital
2025-171.98%
2024-28.68%
2023-196.73%
2022-183.44%
2021-462.24%
2020-359.28%
2019-93.65%
2018-52.52%
2017-3.09%
2016-15.58%
Shares Outstanding
010M20M30M2016201720182019202020212022202320242025
SLN Shares Outstanding by year
PeriodShares Outstanding
202515.74M
202415.55M
202313.21M
202211.98M
202129.65M
202027.67M
201926.34M
201823.53M
201723.34M
201623.27M
Book Value Per Share (USD)
024682016201720182019202020212022202320242025
SLN Book Value Per Share (USD) by year
PeriodBook Value Per Share (USD)
20253.96
20246.89
20231.67
20221.84
20210.29
20200.33
20190.79
20181.49
20172.24
20162.33
Total Assets (USD)
050M100M150M200M2016201720182019202020212022202320242025
SLN Total Assets (USD) by year
PeriodTotal Assets (USD)
2025131.44M
2024161.92M
2023119.45M
2022107.5M
202196.19M
202085.97M
201946.08M
201838.88M
201755.01M
201655.79M
Employee Count
050100150202020212022202320242025
SLN Employee Count by year
PeriodEmployee Count
202588
2024116
2023109
2022122
2021105
202074
Free Cash Flow Yield
-200%-150%-100%-50%0%med -68.43%Dec 24Apr 25Jul 25Nov 25Feb 26Jun 26Sep 26
SLN Free Cash Flow Yield by year
PeriodFree Cash Flow Yield
Sep 26-20.59%
Sep 26-20.66%
Sep 26-18.43%
Aug 26-20.04%
Aug 26-20.27%
Aug 26-19.6%
Aug 26-34.9%
Jul 26-39.76%
Jul 26-37.85%
Jul 26-39.72%
Jul 26-45.89%
Jul 26-40.14%
Jun 26-41.13%
Jun 26-60.19%
Jun 26-62.35%
Jun 26-67.6%
May 26-60.45%
May 26-67.27%
May 26-68.38%
May 26-59.84%
May 26-55.57%
Apr 26-51.46%
Apr 26-52.62%
Apr 26-69.15%
Apr 26-66.7%
Mar 26-80.37%
Mar 26-64.21%
Mar 26-57.42%
Mar 26-63.6%
Feb 26-81.68%
Feb 26-88.87%
Feb 26-99.85%
Feb 26-93.54%
Jan 26-92.19%
Jan 26-78.37%
Jan 26-88.16%
Jan 26-80.5%
Jan 26-72.25%
Dec 25-71.67%
Dec 25-69.75%
Dec 25-70.31%
Dec 25-63.84%
Nov 25-65.93%
Nov 25-70.42%
Nov 25-65.06%
Nov 25-67.53%
Oct 25-69.88%
Oct 25-68.54%
Oct 25-76.97%
Oct 25-100.06%
Oct 25-100.06%
Sep 25-90.31%
Sep 25-102.31%
Sep 25-110.94%
Sep 25-87.93%
Aug 25-104.02%
Aug 25-93.52%
Aug 25-91.13%
Aug 25-99.27%
Aug 25-64.28%
Jul 25-62.55%
Jul 25-65.66%
Jul 25-61.58%
Jul 25-71.85%
Jun 25-68.5%
Jun 25-66.65%
Jun 25-74.41%
Jun 25-72.9%
May 25-67.91%
May 25-78.38%
May 25-90.75%
May 25-107.19%
May 25-128.65%
Apr 25-150.98%
Apr 25-160.98%
Apr 25-194.01%
Apr 25-188.19%
Mar 25-143.18%
Mar 25-138.22%
Mar 25-126.08%
Mar 25-101.52%
Feb 25-106.5%
Feb 25-77.65%
Feb 25-76.6%
Feb 25-72.91%
Jan 25-68.48%
Jan 25-64.61%
Jan 25-70.01%
Jan 25-60.04%
Jan 25-49.51%
Dec 24-52.19%
Dec 24-53.78%
Dec 24-57.63%
Dec 24-44.05%
Nov 24-47.37%
Nov 24-52.65%
Nov 24-29.27%
Nov 24-14.86%
Nov 24-14.73%
Oct 24-14.45%
Price to Sales
0100200300400med 3.94Dec 24Apr 25Jul 25Nov 25Feb 26Jun 26Sep 26
SLN Price to Sales by year
PeriodPrice to Sales
Sep 26334.75
Sep 26333.73
Sep 26373.97
Aug 26343.98
Aug 26340.14
Aug 26351.67
Aug 26204.18
Jul 26179.23
Jul 26188.29
Jul 26179.4
Jul 26155.31
Jul 26177.53
Jun 26173.25
Jun 26118.41
Jun 26114.31
Jun 26105.42
May 26117.89
May 26105.93
May 26104.23
May 26119.09
May 26164.14
Apr 26177.27
Apr 26173.35
Apr 26131.91
Apr 26136.75
Mar 26113.5
Mar 26142.04
Mar 26158.85
Mar 26143.43
Feb 263.43
Feb 263.15
Feb 262.81
Feb 262.99
Jan 263.04
Jan 263.57
Jan 263.18
Jan 263.48
Jan 263.88
Dec 253.91
Dec 254.02
Dec 253.98
Dec 254.39
Nov 254.25
Nov 253.98
Nov 254.31
Nov 254.15
Oct 254.34
Oct 254.43
Oct 253.94
Oct 253.03
Oct 253.03
Sep 253.36
Sep 252.97
Sep 252.74
Sep 253.45
Aug 252.92
Aug 253.24
Aug 253.33
Aug 253.06
Aug 253.7
Jul 253.8
Jul 253.62
Jul 253.86
Jul 253.31
Jun 253.47
Jun 253.57
Jun 253.2
Jun 253.26
May 253.5
May 253.03
May 252.62
May 252.22
May 251.1
Apr 250.94
Apr 250.88
Apr 250.73
Apr 250.75
Mar 250.99
Mar 251.03
Mar 251.13
Mar 251.4
Feb 251.33
Feb 253.05
Feb 253.09
Feb 253.24
Jan 253.45
Jan 253.66
Jan 253.38
Jan 253.94
Jan 254.78
Dec 244.53
Dec 244.4
Dec 244.1
Dec 245.37
Nov 244.99
Nov 244.49
Nov 248.08
Nov 249.97
Nov 2410.06
Oct 2410.25
Price/Operating Cashflow
02505007501000med 120.74Nov 20Jan 21Sep 21Dec 21Mar 22Jun 22Aug 22
SLN Price/Operating Cashflow by year
PeriodPrice/Operating Cashflow
Aug 2219.9
Aug 2217.58
Aug 2217.83
Aug 2218.25
Jul 2218.47
Jul 2218.37
Jul 2220.65
Jul 2220.84
Jul 2221.87
Jun 2221.36
Jun 2216.21
Jun 2215.62
Jun 2216.23
May 2234.14
May 2229.45
May 2235.19
May 2243.1
Apr 2242.13
Apr 2253.65
Apr 2256.96
Apr 2258.48
Apr 2264.78
Mar 2263.59
Mar 2255.78
Mar 22106.33
Mar 22106.76
Feb 22113.23
Feb 22115.95
Feb 22139.2
Feb 22129.99
Jan 22120.74
Jan 22122.17
Jan 22131.25
Jan 22142.88
Dec 21146.5
Dec 21144.79
Dec 21149.1
Dec 21154.57
Dec 21161.2
Nov 21211.94
Nov 21219.35
Nov 21217.46
Nov 21217.85
Oct 21206.22
Oct 21214.79
Oct 21203.98
Oct 21198.92
Oct 21195.52
Sep 21204.76
Sep 21202.61
Sep 21208.4
Sep 21213.7
Mar 21757.85
Mar 21745.55
Mar 21792.09
Mar 21739.99
Feb 21807.05
Feb 21863.92
Feb 21818.86
Feb 21788
Jan 21811.91
Jan 21786.55
Jan 21720.48
Jan 21767.72
Dec 20716.45
Dec 20656.91
Dec 20624.89
Dec 20645.66
Dec 20571.23
Nov 2027.55
Nov 2026.35
Nov 2031.76
Nov 2025.13
Oct 2024.29
Oct 2024.92
Oct 2025.18
Oct 2026.38
Oct 2027.36
Sep 2028.8
Sep 2030.03
Sep 2031.95
Price to Book
0246med 1.34Sep 24Jan 25Apr 25Nov 25Feb 26Jun 26Sep 26
SLN Price to Book by year
PeriodPrice to Book
Sep 265.35
Sep 265.33
Sep 265.97
Aug 265.49
Aug 265.43
Aug 265.62
Aug 263.81
Jul 263.34
Jul 263.51
Jul 263.35
Jul 262.9
Jul 263.31
Jun 263.23
Jun 262.21
Jun 262.13
Jun 261.97
May 262.2
May 261.98
May 261.94
May 262.22
May 261.8
Apr 261.95
Apr 261.9
Apr 261.45
Apr 261.5
Mar 261.25
Mar 261.56
Mar 261.74
Mar 261.57
Feb 261.16
Feb 261.06
Feb 260.95
Feb 261.01
Jan 261.02
Jan 261.21
Jan 261.07
Jan 261.17
Jan 261.31
Dec 251.32
Dec 251.35
Dec 251.34
Dec 251.48
Nov 251.43
Nov 251.34
Nov 251.45
Nov 251.4
Oct 251.2
Oct 251.22
Oct 251.09
Oct 250.84
Oct 250.84
Sep 250.93
Sep 250.82
Sep 250.75
Sep 250.95
Aug 250.8
Aug 250.89
Aug 250.92
Aug 250.84
May 250.43
Apr 250.37
Apr 250.34
Apr 250.29
Apr 250.29
Mar 250.39
Mar 250.4
Mar 250.44
Mar 250.55
Feb 250.52
Feb 250.63
Feb 250.64
Feb 250.67
Jan 250.71
Jan 250.76
Jan 250.7
Jan 250.81
Jan 250.99
Dec 240.94
Dec 240.91
Dec 240.85
Dec 241.11
Nov 241.03
Nov 240.93
Nov 241.67
Nov 241.88
Nov 241.89
Oct 241.93
Oct 241.91
Oct 242.08
Oct 241.97
Sep 241.89
Sep 241.9
Sep 241.97
Sep 241.97
Aug 242.01
Aug 241.7
Aug 241.68
Aug 241.21
Aug 241.38
Jul 241.53
Silence Therapeutics plc
SLN
Stockpicker

Video analysis: SLN

All videos

No video analysis for this stock yet. Request one from our team.

Your email is used only to follow up on this request. We do not add you to marketing lists. Privacy Policy

News: SLN

Silence Therapeutics Announces Closing of Upsized Public Offering and Full Exercise of Underwriters' Option to Purchase Additional ADSs

businesswire.com · 14 Aug 2026

Silence Therapeutics Announces Closing of Upsized Public Offering and Full Exercise of Underwriters' Option to Purchase Additional ADSs

LONDON--(BUSINESS WIRE)---- $SLN #SenseofSilence--Silence Therapeutics plc, (Nasdaq: SLN), (“Silence” or the “Company”), a global clinical-stage biotechnology company developing novel short interfering RNA (“siRNA”) therapies, today announced the closing of its previously announced underwritten public offering of 14,907,407 American Depositary Shares (“ADSs”), each representing three ordinary shares of £0.05 each in the capital of the Company, in the United States at a public offering price of $13.50 per ADS, which inc.

Wall Street Analysts Predict a 140.06% Upside in Silence Therapeutics (SLN): Here's What You Should Know

zacks.com · 13 Aug 2026

Wall Street Analysts Predict a 140.06% Upside in Silence Therapeutics (SLN): Here's What You Should Know

The average of price targets set by Wall Street analysts indicates a potential upside of 140.1% in Silence Therapeutics (SLN). While the effectiveness of this highly sought-after metric is questionable, the positive trend in earnings estimate revisions might translate into an upside in the stock.

Silence Therapeutics Announces Pricing of Upsized $175 Million Underwritten Public Offering

businesswire.com · 11 Aug 2026

Silence Therapeutics Announces Pricing of Upsized $175 Million Underwritten Public Offering

LONDON--(BUSINESS WIRE)---- $SLN #SenseofSilence--Silence Therapeutics plc (“Silence” or the “Company”) , a global clinical-stage biotechnology company developing novel short interfering RNA (“siRNA”) therapies, today announced that it has priced its previously announced underwritten public offering of 12,962,963 American Depositary Shares (“ADSs”), each representing three ordinary shares of £0.05 each in the capital of the Company, in the United States at a public offering price of $13.50 per ADS. In addition, Silence.

Silence Therapeutics’ Divesiran Hits Phase II Goal, Sets Up Phase III PV Trial

defenseworld.net · 11 Aug 2026

Silence Therapeutics’ Divesiran Hits Phase II Goal, Sets Up Phase III PV Trial

Silence Therapeutics (NASDAQ: SLN) reported top-line results from its Phase II SANRECO trial of divesiran in patients with phlebotomy-dependent polycythemia vera, or PV, with the study meeting its primary endpoint and supporting the company's plan to advance a quarterly dosing regimen into Phase III. PV is a rare myeloproliferative neoplasm in which elevated hematocrit levels can

Silence Therapeutics' Divesiran Hits Phase II Goal, Sets Up Phase III PV Trial

marketbeat.com · 11 Aug 2026

Silence Therapeutics' Divesiran Hits Phase II Goal, Sets Up Phase III PV Trial

Silence Therapeutics NASDAQ: SLN reported top-line results from its Phase II SANRECO trial of divesiran in patients with phlebotomy-dependent polycythemia vera, or PV, with the study meeting its primary endpoint and supporting the company's plan to advance a quarterly dosing regimen into Phase III.

Silence Therapeutics plc (SLN) Discusses Top-Line Results From SANRECO Phase II Trial of Divesiran in Polycythemia Vera Transcript

seekingalpha.com · 10 Aug 2026

Silence Therapeutics plc (SLN) Discusses Top-Line Results From SANRECO Phase II Trial of Divesiran in Polycythemia Vera Transcript

Silence Therapeutics plc (SLN) Discusses Top-Line Results From SANRECO Phase II Trial of Divesiran in Polycythemia Vera Transcript

Silence Therapeutics Announces Proposed Public Offering of $150 Million of American Depositary Shares

businesswire.com · 10 Aug 2026

Silence Therapeutics Announces Proposed Public Offering of $150 Million of American Depositary Shares

LONDON--(BUSINESS WIRE)---- $SLN #SenseofSilence--Silence Therapeutics plc (“Silence” or the “Company”), a global clinical-stage biotechnology company developing novel short interfering RNA (“siRNA”) therapies, today announced that it has commenced an underwritten public offering of approximately $150 million of its American Depositary Shares (“ADSs”), each representing three ordinary shares of £0.05 each in the capital of the Company, in the United States. The proposed offering is a public offering registered under th.

Silence Therapeutics Says Blood Cancer Trial Delivers 'Best-Case Outcome'

benzinga.com · 10 Aug 2026

Silence Therapeutics Says Blood Cancer Trial Delivers 'Best-Case Outcome'

Silence Therapeutics plc (NASDAQ:SLN) stock is trading higher on Monday after the company reported positive topline outcomes from its Phase 2 SANRECO study assessing divesiran for polycythemia vera. It is a rare, slow-growing blood cancer where the bone marrow makes too many red blood cells.

Similar companies

Disclaimer: The historical data presented on this platform is provided by Financial Modeling Prep. Stock Picker is a platform for informational purposes only and does not provide financial advice. Users are encouraged to conduct their own research and consult with a qualified financial advisor before making investment decisions.