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Rhythm Pharmaceuticals, Inc.

$104.71 -$0.30 (-0.29%)
NASDAQ · 11 Sep 2026 20:00 UTC
Previous Close
$102.2
Day Range
$102.25$106.57
Year Range
$74.5$122.2
Market Cap
7.18B
AVG Volume
735.89K
Trailing/Forward PE
-33.67/-
PEG ratio
0.43
Dividend Yield
-
Next Earnings Date
2026-11-03
Primary Exchange
NASDAQUS
Revenue (USD)
050M100M150M200M2016201720182019202020212022202320242025
RYTM Revenue (USD) by year
PeriodRevenue (USD)
2025189.76M
2024130.13M
202377.43M
202223.64M
20213.15M
20200
20190
20180
20170
20160
Net Income (USD)
-300M-200M-100M02016201720182019202020212022202320242025
RYTM Net Income (USD) by year
PeriodNet Income (USD)
2025-196.54M
2024-260.57M
2023-184.68M
2022-181.12M
2021-69.61M
2020-134M
2019-140.73M
2018-74.06M
2017-33.71M
2016-27.47M
Operating Income (USD)
-300M-200M-100M02016201720182019202020212022202320242025
RYTM Operating Income (USD) by year
PeriodOperating Income (USD)
2025-192.02M
2024-265.5M
2023-184.35M
2022-179.16M
2021-170.06M
2020-136.57M
2019-146M
2018-78.42M
2017-32.41M
2016-25.91M
EBITDA (USD)
-300M-200M-100M02016201720182019202020212022202320242025
RYTM EBITDA (USD) by year
PeriodEBITDA (USD)
2025-174.12M
2024-238.61M
2023-168.29M
2022-174.25M
2021-168.61M
2020-135.88M
2019-145.17M
2018-77.97M
2017-32.19M
2016-20.38M
Cash Flows (USD)
-200M-150M-100M-50M02016201720182019202020212022202320242025
RYTM Cash Flows (USD) by year
PeriodCash Flows (USD)
2025-116.63M
2024-153.88M
2023-137.08M
2022-177.71M
2021-151.44M
2020-122.19M
2019-126.14M
2018-62.78M
2017-29.59M
2016-24.28M
EPS (USD)
-6-4-202016201720182019202020212022202320242025
RYTM EPS (USD) by year
PeriodEPS (USD)
2025-3.11
2024-4.31
2023-3.19
2022-3.52
2021-1.35
2020-3.05
2019-3.9
2018-2.38
2017-1.42
2016-2.13
Expenses (USD)
0200M400M600MR&DSG&ACapex2016201720182019202020212022202320242025
RYTM Expenses (USD) by year
PeriodExpenses (USD)
2025363.23M
2024421.89M
2023253.4M
2022204.94M
2021178.05M
2020136.79M
2019149.38M
201879.14M
201732.55M
201626.96M
Cash & Debt (USD)
0100M200M300M400M2016201720182019202020212022202320242025
RYTM Cash & Debt (USD) by year
PeriodCash & Debt (USD)
2025388.95M
2024320.56M
2023275.85M
2022333.29M
2021294.86M
2020172.79M
2019292.46M
2018252.06M
2017148.08M
201610.54M
Debt ratios
00.511.5220182019202020212022202320242025
RYTM Debt ratios by year
PeriodDebt ratios
20250.51
20240.42
20230.42
20220.53
20210.55
20200.43
20191.05
20181.91
Margins
0%25%50%75%100%20212022202320242025
RYTM Margins by year
PeriodMargins
202589.73%
202489.73%
202387.99%
202290.98%
202181.01%
Return on Capital
-400%-300%-200%-100%0%2016201720182019202020212022202320242025
RYTM Return on Capital by year
PeriodReturn on Capital
2025-72.79%
2024-158.35%
2023-108.79%
2022-68.54%
2021-24.5%
2020-80.46%
2019-50.08%
2018-30.08%
2017-23.28%
2016-376.43%
Shares Outstanding
020M40M60M80M2016201720182019202020212022202320242025
RYTM Shares Outstanding by year
PeriodShares Outstanding
202566.88M
202461.6M
202359.21M
202256.3M
202150.27M
202044.03M
201942.21M
201834.4M
201726.17M
201616.73M
Book Value Per Share (USD)
024682016201720182019202020212022202320242025
RYTM Book Value Per Share (USD) by year
PeriodBook Value Per Share (USD)
20254.04
20242.67
20232.87
20224.69
20215.65
20203.78
20196.66
20187.16
20175.53
20160.44
Total Assets (USD)
0200M400M600M2016201720182019202020212022202320242025
RYTM Total Assets (USD) by year
PeriodTotal Assets (USD)
2025480.2M
2024392.27M
2023332.75M
2022382.48M
2021329.52M
2020187.07M
2019308.52M
2018260.21M
2017151.74M
201612.34M
Employee Count
0200400600201720182019202020212022202320242025
RYTM Employee Count by year
PeriodEmployee Count
2025414
2024283
2023226
2022177
2021140
202090
201970
201854
201726
Free Cash Flow Yield
-6%-4%-2%0%med -2.02%Dec 24Apr 25Jul 25Oct 25Feb 26May 26Sep 26
RYTM Free Cash Flow Yield by year
PeriodFree Cash Flow Yield
Sep 26-2.1%
Sep 26-2.14%
Aug 26-2.05%
Aug 26-1.99%
Aug 26-1.9%
Aug 26-1.9%
Jul 26-1.79%
Jul 26-1.74%
Jul 26-1.66%
Jul 26-1.63%
Jul 26-1.55%
Jun 26-1.61%
Jun 26-1.83%
Jun 26-2.01%
Jun 26-2.05%
May 26-2.01%
May 26-2.02%
May 26-1.96%
May 26-1.88%
May 26-2.13%
Apr 26-2.03%
Apr 26-1.97%
Apr 26-2.07%
Apr 26-2.02%
Mar 26-2.3%
Mar 26-1.99%
Mar 26-2%
Mar 26-1.86%
Feb 26-1.88%
Feb 26-1.7%
Feb 26-1.73%
Feb 26-1.64%
Jan 26-1.65%
Jan 26-1.65%
Jan 26-1.67%
Jan 26-1.68%
Jan 26-1.62%
Dec 25-1.54%
Dec 25-1.51%
Dec 25-1.49%
Dec 25-1.62%
Nov 25-1.55%
Nov 25-1.67%
Nov 25-1.71%
Nov 25-1.69%
Oct 25-1.49%
Oct 25-1.53%
Oct 25-1.53%
Oct 25-1.68%
Oct 25-1.71%
Sep 25-1.71%
Sep 25-1.76%
Sep 25-1.76%
Sep 25-1.66%
Aug 25-1.64%
Aug 25-1.64%
Aug 25-1.73%
Aug 25-1.84%
Aug 25-2.04%
Jul 25-2.08%
Jul 25-2.02%
Jul 25-2.08%
Jul 25-2.74%
Jun 25-2.87%
Jun 25-2.9%
Jun 25-2.86%
Jun 25-2.64%
May 25-2.93%
May 25-2.89%
May 25-3%
May 25-3.14%
May 25-3.9%
Apr 25-3.92%
Apr 25-4.05%
Apr 25-4.2%
Apr 25-5.32%
Mar 25-4.56%
Mar 25-4.8%
Mar 25-4.9%
Mar 25-4.92%
Feb 25-4.55%
Feb 25-4.79%
Feb 25-4.74%
Feb 25-4.54%
Jan 25-4.52%
Jan 25-4.65%
Jan 25-4.92%
Jan 25-4.78%
Jan 25-4.5%
Dec 24-4.83%
Dec 24-4.79%
Dec 24-4.86%
Dec 24-4.56%
Nov 24-4.33%
Nov 24-4.48%
Nov 24-4.78%
Nov 24-3.99%
Nov 24-5.63%
Oct 24-5.69%
Oct 24-5.43%
Price to Sales
20304050med 31.44Dec 24Apr 25Jul 25Oct 25Feb 26May 26Sep 26
RYTM Price to Sales by year
PeriodPrice to Sales
Sep 2629.94
Sep 2629.37
Aug 2630.64
Aug 2631.45
Aug 2633.02
Aug 2633.06
Jul 2631.07
Jul 2631.96
Jul 2633.37
Jul 2633.93
Jul 2635.74
Jun 2634.38
Jun 2630.3
Jun 2627.66
Jun 2627.04
May 2627.64
May 2627.49
May 2628.33
May 2629.48
May 2628.83
Apr 2630.2
Apr 2631.26
Apr 2629.74
Apr 2630.41
Mar 2626.72
Mar 2630.82
Mar 2630.8
Mar 2632.96
Feb 2632.68
Feb 2636.83
Feb 2636.2
Feb 2638.24
Jan 2637.84
Jan 2637.97
Jan 2637.51
Jan 2637.29
Jan 2638.76
Dec 2540.6
Dec 2541.39
Dec 2541.91
Dec 2538.61
Nov 2540.27
Nov 2537.55
Nov 2536.69
Nov 2537.02
Oct 2546.36
Oct 2545.01
Oct 2544.94
Oct 2541.08
Oct 2540.35
Sep 2540.41
Sep 2539.14
Sep 2539.21
Sep 2541.61
Aug 2542.03
Aug 2542.08
Aug 2539.77
Aug 2537.48
Aug 2540.68
Jul 2539.83
Jul 2541.1
Jul 2539.95
Jul 2530.3
Jun 2528.9
Jun 2528.56
Jun 2528.98
Jun 2531.38
May 2528.26
May 2528.73
May 2527.61
May 2526.44
May 2530.3
Apr 2530.18
Apr 2529.23
Apr 2528.19
Apr 2522.22
Mar 2525.94
Mar 2524.63
Mar 2524.13
Mar 2524.04
Feb 2525.99
Feb 2530.5
Feb 2530.84
Feb 2532.2
Jan 2532.33
Jan 2531.43
Jan 2529.67
Jan 2530.56
Jan 2532.44
Dec 2430.24
Dec 2430.53
Dec 2430.05
Dec 2432.04
Nov 2433.75
Nov 2432.61
Nov 2430.59
Nov 2436.63
Nov 2429.38
Oct 2429.1
Oct 2430.48
Price to Book
102030405060med 23.89Dec 24Apr 25Jul 25Oct 25Feb 26May 26Sep 26
RYTM Price to Book by year
PeriodPrice to Book
Sep 2633.05
Sep 2632.43
Aug 2633.83
Aug 2634.72
Aug 2636.45
Aug 2636.5
Jul 2628.39
Jul 2629.21
Jul 2630.49
Jul 2631.01
Jul 2632.66
Jun 2631.42
Jun 2627.69
Jun 2625.28
Jun 2624.72
May 2625.27
May 2625.13
May 2625.89
May 2626.94
May 2620.26
Apr 2621.23
Apr 2621.97
Apr 2620.9
Apr 2621.37
Mar 2618.78
Mar 2621.66
Mar 2621.64
Mar 2623.16
Feb 2622.97
Feb 2621.71
Feb 2621.34
Feb 2622.55
Jan 2622.31
Jan 2622.39
Jan 2622.12
Jan 2621.98
Jan 2622.85
Dec 2523.94
Dec 2524.4
Dec 2524.71
Dec 2522.76
Nov 2523.74
Nov 2522.14
Nov 2521.63
Nov 2521.83
Oct 2554.23
Oct 2552.67
Oct 2552.57
Oct 2548.06
Oct 2547.21
Sep 2547.27
Sep 2545.8
Sep 2545.87
Sep 2548.68
Aug 2549.18
Aug 2549.23
Aug 2546.53
Aug 2543.85
Aug 2534.14
Jul 2533.43
Jul 2534.49
Jul 2533.52
Jul 2525.43
Jun 2524.25
Jun 2523.97
Jun 2524.32
Jun 2526.33
May 2523.71
May 2524.11
May 2523.17
May 2522.19
May 2523.96
Apr 2523.87
Apr 2523.11
Apr 2522.29
Apr 2517.57
Mar 2520.51
Mar 2519.48
Mar 2519.08
Mar 2519.01
Feb 2520.55
Feb 2522.48
Feb 2522.73
Feb 2523.73
Jan 2523.83
Jan 2523.17
Jan 2521.87
Jan 2522.52
Jan 2523.9
Dec 2422.29
Dec 2422.5
Dec 2422.15
Dec 2423.61
Nov 2424.87
Nov 2424.03
Nov 2422.54
Nov 2426.99
Nov 2416.66
Oct 2416.5
Oct 2417.28
Rhythm Pharmaceuticals, Inc.
RYTM
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News: RYTM

Rhythm Pharmaceuticals Announces New Data Presentations at the European Society for Paediatric Endocrinology Meeting

globenewswire.com · 10 Sep 2026

Rhythm Pharmaceuticals Announces New Data Presentations at the European Society for Paediatric Endocrinology Meeting

-- Real-world data showed reductions in BMI with up to 18 months of setmelanotide therapy in 30 paediatric patients with acquired hypothalamic obesity (HO) in France – -- Phase 3 analyses demonstrated improvements across multiple cardiometabolic risk indices with setmelanotide in acquired HO -- BOSTON, Sept. 10, 2026 (GLOBE NEWSWIRE) -- Rhythm Pharmaceuticals, Inc. (Nasdaq: RYTM), a global commercial-stage biopharmaceutical company focused on transforming the lives of patients living with rare neuroendocrine diseases, today announced Rhythm and its collaborators will present three posters and three oral presentations relating to the company's work in rare melanocortin-4 receptor (MC4R) pathway diseases at the 64th Annual European Society for Paediatric Endocrinology (ESPE) Meeting taking place September 8-10 in Marseille, France.

Here Are Friday’s Top Wall Street Analyst Research Calls: Baozun, Commerce Bancshares, Element Solutions, Evolution Petroleum, Petrobras, Rythm Pharmaceuticals, Terawulf, UMB Financial, Workday, and More

247wallst.com · 28 Aug 2026

Here Are Friday’s Top Wall Street Analyst Research Calls: Baozun, Commerce Bancshares, Element Solutions, Evolution Petroleum, Petrobras, Rythm Pharmaceuticals, Terawulf, UMB Financial, Workday, and More

NVIDIA's blockbuster earnings sent shockwaves through tech on Thursday, but Wall Street analysts were busy reshaping the landscape elsewhere, issuing a flurry of upgrades, downgrades, and fresh initiations across energy, crypto infrastructure, banking, and biotech.

Bank of New York Mellon Corp Purchases Shares of 394,044 Rhythm Pharmaceuticals, Inc. $RYTM

defenseworld.net · 28 Aug 2026

Bank of New York Mellon Corp Purchases Shares of 394,044 Rhythm Pharmaceuticals, Inc. $RYTM

Bank of New York Mellon Corp acquired a new position in Rhythm Pharmaceuticals, Inc. (NASDAQ: RYTM) in the second quarter, according to its most recent 13F filing with the Securities and Exchange Commission. The fund acquired 394,044 shares of the company's stock, valued at approximately $43,751,000. Bank of New York Mellon Corp owned

Billionaire Stanley Druckenmiller Is Quietly Loading Up on Healthcare Stocks -- Here's What His New Positions Reveal

fool.com · 26 Aug 2026

Billionaire Stanley Druckenmiller Is Quietly Loading Up on Healthcare Stocks -- Here's What His New Positions Reveal

Duquesne Family Office has beefed up its healthcare holdings.

Rhythm Pharmaceuticals Announces MHLW Approval of IMCIVREE® (setmelanotide) for Patients with Acquired Hypothalamic Obesity (HO) in Japan

globenewswire.com · 24 Aug 2026

Rhythm Pharmaceuticals Announces MHLW Approval of IMCIVREE® (setmelanotide) for Patients with Acquired Hypothalamic Obesity (HO) in Japan

-- Approximately 5,000 to 8,000 patients estimated to be living with acquired HO in Japan --  -- Commercial launch in Japan expected by end of 2026, pending final pricing determination --

Eli Lilly and Novo Nordisk Can't Treat This Form of Obesity. Billionaire Stanley Druckenmiller Is Betting Rhythm Pharmaceuticals Can

fool.com · 23 Aug 2026

Eli Lilly and Novo Nordisk Can't Treat This Form of Obesity. Billionaire Stanley Druckenmiller Is Betting Rhythm Pharmaceuticals Can

Rhythm Pharmaceuticals develops medicines for rare forms of obesity. The company has little competition in its target market.

Rhythm Pharmaceuticals: Building A Defensive MC4R Franchise

seekingalpha.com · 18 Aug 2026

Rhythm Pharmaceuticals: Building A Defensive MC4R Franchise

Rhythm Pharmaceuticals is transitioning from a single rare disease drug to a broad MC4R therapeutic franchise, leveraging multiple formulations for market segmentation. IMCIVREE's AHO approval and over 400 patient start forms signal robust demand, with a scalable commercial model targeting endocrinologists and neuro-oncologists. RYTM's pipeline—daily, weekly, and oral MC4R agonists—aims to preempt competition and expand reach, while strong gross margins offer operating leverage.

Rhythm Pharmaceuticals Announces Appointment of Manher (AJ) Joshi as Chief Medical Officer

globenewswire.com · 17 Aug 2026

Rhythm Pharmaceuticals Announces Appointment of Manher (AJ) Joshi as Chief Medical Officer

BOSTON, Aug. 17, 2026 (GLOBE NEWSWIRE) -- Rhythm Pharmaceuticals, Inc. (Nasdaq: RYTM), a global commercial-stage biopharmaceutical company focused on transforming the lives of patients living with rare neuroendocrine diseases, today announced the appointment of Manher “AJ” Joshi, M.D., as Chief Medical Officer, effective August 17.

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