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Aprea Therapeutics, Inc.

$0.77 -$0.08 (-9.27%)
NASDAQ · 11 Sep 2026 20:00 UTC
Previous Close
$0.79
Day Range
$0.77$0.82
Year Range
$0.55$1.69
Market Cap
9.58M
AVG Volume
216.41K
Trailing/Forward PE
-0.6/-
PEG ratio
-0.52
Dividend Yield
-
Next Earnings Date
2026-11-11
Primary Exchange
NASDAQUS
Revenue (USD)
0200K400K600K24 Q124 Q224 Q324 Q425 Q125 Q225 Q325 Q426 Q126 Q2
APRE Revenue (USD) by quarter
PeriodRevenue (USD)
26 Q20
26 Q10
25 Q40
25 Q30
25 Q2118.11K
25 Q1162.46K
24 Q4205.82K
24 Q3354.62K
24 Q2561.57K
24 Q1380.57K
Net Income (USD)
-4M-3M-2M-1M024 Q124 Q224 Q324 Q425 Q125 Q225 Q325 Q426 Q126 Q2
APRE Net Income (USD) by quarter
PeriodNet Income (USD)
26 Q2-3.59M
26 Q1-3.29M
25 Q4-2.46M
25 Q3-2.97M
25 Q2-3.24M
25 Q1-3.93M
24 Q4-2.89M
24 Q3-3.78M
24 Q2-3.47M
24 Q1-2.81M
Operating Income (USD)
-6M-4M-2M024 Q124 Q224 Q324 Q425 Q125 Q225 Q325 Q426 Q126 Q2
APRE Operating Income (USD) by quarter
PeriodOperating Income (USD)
26 Q2-4.03M
26 Q1-3.43M
25 Q4-2.64M
25 Q3-3.12M
25 Q2-3.39M
25 Q1-4.09M
24 Q4-3.23M
24 Q3-4.1M
24 Q2-3.85M
24 Q1-3.15M
EBITDA (USD)
-4M-3M-2M-1M024 Q124 Q224 Q324 Q425 Q125 Q225 Q325 Q426 Q126 Q2
APRE EBITDA (USD) by quarter
PeriodEBITDA (USD)
26 Q2-3.59M
26 Q1-3.28M
25 Q4-2.45M
25 Q3-2.97M
25 Q2-3.23M
25 Q1-3.93M
24 Q4-2.89M
24 Q3-3.78M
24 Q2-3.46M
24 Q1-2.8M
Cash Flows (USD)
-4M-3M-2M-1M024 Q124 Q224 Q324 Q425 Q125 Q225 Q325 Q426 Q126 Q2
APRE Cash Flows (USD) by quarter
PeriodCash Flows (USD)
26 Q2-3.29M
26 Q1-2.76M
25 Q4-2.96M
25 Q3-3.17M
25 Q2-3.13M
25 Q1-3.63M
24 Q4-3.51M
24 Q3-2.47M
24 Q2-3.65M
24 Q1-3.94M
EPS (USD)
-0.8-0.6-0.4-0.2-024 Q124 Q224 Q324 Q425 Q125 Q225 Q325 Q426 Q126 Q2
APRE EPS (USD) by quarter
PeriodEPS (USD)
26 Q2-0.07
26 Q1-0.43
25 Q4-0.32
25 Q3-0.47
25 Q2-0.53
25 Q1-0.66
24 Q4-0.49
24 Q3-0.64
24 Q2-0.58
24 Q1-0.67
Expenses (USD)
02M4M6MR&DSG&ACapex24 Q124 Q224 Q324 Q425 Q125 Q225 Q325 Q426 Q126 Q2
APRE Expenses (USD) by quarter
PeriodExpenses (USD)
26 Q24.05M
26 Q13.42M
25 Q42.65M
25 Q33.12M
25 Q23.51M
25 Q14.25M
24 Q43.43M
24 Q34.45M
24 Q24.42M
24 Q13.54M
Cash & Debt (USD)
020M40M60MCashShort Term Debt24 Q124 Q224 Q324 Q425 Q125 Q225 Q325 Q426 Q126 Q2
APRE Cash & Debt (USD) by quarter
PeriodCash & Debt (USD)
26 Q241.23M
26 Q146.47M
25 Q414.6M
25 Q313.72M
25 Q216.53M
25 Q119.28M
24 Q422.85M
24 Q326.25M
24 Q228.69M
24 Q132.37M
Debt ratios
0123424 Q124 Q224 Q324 Q425 Q125 Q225 Q325 Q426 Q126 Q2
APRE Debt ratios by quarter
PeriodDebt ratios
26 Q23.36
26 Q13.89
25 Q41.16
25 Q31.05
25 Q21.2
25 Q11.37
24 Q41.77
24 Q31.95
24 Q22.22
24 Q12.55
Margins
-15000%-10000%-5000%0%23 Q223 Q323 Q424 Q124 Q224 Q324 Q425 Q125 Q2
APRE Margins by quarter
PeriodMargins
25 Q2-1519%
25 Q1-1428.39%
24 Q4-1046.21%
24 Q3-702.66%
24 Q2-355.45%
24 Q1-320.52%
23 Q4-14434.2%
23 Q3-564.42%
23 Q2-782.16%
Return on Capital
-30%-20%-10%0%24 Q124 Q224 Q324 Q425 Q125 Q225 Q325 Q426 Q126 Q2
APRE Return on Capital by quarter
PeriodReturn on Capital
26 Q2-9.34%
26 Q1-7.68%
25 Q4-19.74%
25 Q3-25.54%
25 Q2-24.14%
25 Q1-25.29%
24 Q4-14.99%
24 Q3-17.24%
24 Q2-12.91%
24 Q1-9.72%
Shares Outstanding
020M40M60M24 Q124 Q224 Q324 Q425 Q125 Q225 Q325 Q426 Q126 Q2
APRE Shares Outstanding by quarter
PeriodShares Outstanding
26 Q253.48M
26 Q17.69M
25 Q47.69M
25 Q36.37M
25 Q26.08M
25 Q15.99M
24 Q45.95M
24 Q35.94M
24 Q25.94M
24 Q14.2M
Book Value Per Share (USD)
0246824 Q124 Q224 Q324 Q425 Q125 Q225 Q325 Q426 Q126 Q2
APRE Book Value Per Share (USD) by quarter
PeriodBook Value Per Share (USD)
26 Q20.72
26 Q15.57
25 Q41.62
25 Q31.83
25 Q22.21
25 Q12.59
24 Q43.24
24 Q33.69
24 Q24.53
24 Q16.89
Total Assets (USD)
020M40M60M24 Q124 Q224 Q324 Q425 Q125 Q225 Q325 Q426 Q126 Q2
APRE Total Assets (USD) by quarter
PeriodTotal Assets (USD)
26 Q242.29M
26 Q148.11M
25 Q415.93M
25 Q314.32M
25 Q217.31M
25 Q120.22M
24 Q423.98M
24 Q326.89M
24 Q229.96M
24 Q133.2M
Employee Count
051015202019202020212022202320242025
APRE Employee Count by quarter
PeriodEmployee Count
20258
20248
20237
20229
202116
202017
201913
Free Cash Flow Yield
-400%-300%-200%-100%0%med -137.82%Dec 24Apr 25Jul 25Oct 25Feb 26May 26Sep 26
APRE Free Cash Flow Yield by quarter
PeriodFree Cash Flow Yield
Sep 26-29.43%
Sep 26-28.68%
Aug 26-27.16%
Aug 26-35.58%
Aug 26-33.5%
Aug 26-240.42%
Jul 26-252.17%
Jul 26-247.39%
Jul 26-220.36%
Jul 26-209.86%
Jul 26-211%
Jun 26-197.91%
Jun 26-218.67%
Jun 26-227.88%
Jun 26-210.88%
May 26-175.16%
May 26-164.58%
May 26-168.1%
May 26-171.16%
May 26-205.04%
Apr 26-180.37%
Apr 26-167.72%
Apr 26-182.94%
Apr 26-234.45%
Mar 26-245.57%
Mar 26-220.05%
Mar 26-286.62%
Mar 26-234.34%
Feb 26-230.12%
Feb 26-278.38%
Feb 26-346.17%
Feb 26-305.73%
Jan 26-265.02%
Jan 26-254.16%
Jan 26-237.03%
Jan 26-223.19%
Jan 26-247.31%
Dec 25-215.22%
Dec 25-226.83%
Dec 25-225.64%
Dec 25-199.01%
Nov 25-167.42%
Nov 25-180.3%
Nov 25-174.34%
Nov 25-170.28%
Oct 25-149.6%
Oct 25-149.6%
Oct 25-133.4%
Oct 25-147.5%
Oct 25-139.63%
Sep 25-143.45%
Sep 25-145.45%
Sep 25-136%
Sep 25-135.12%
Aug 25-133.4%
Aug 25-126.94%
Aug 25-123.93%
Aug 25-130.13%
Aug 25-133.26%
Jul 25-117.05%
Jul 25-133.26%
Jul 25-127.87%
Jul 25-127.14%
Jun 25-131.68%
Jun 25-134.89%
Jun 25-120.23%
Jun 25-126.41%
May 25-127.14%
May 25-132.47%
May 25-118.93%
May 25-140.69%
May 25-123.2%
Apr 25-143.35%
Apr 25-151.95%
Apr 25-147.05%
Apr 25-134.07%
Mar 25-109.05%
Mar 25-98.15%
Mar 25-97.74%
Mar 25-100.68%
Feb 25-92.72%
Feb 25-89.53%
Feb 25-65.34%
Feb 25-61.25%
Jan 25-59.99%
Jan 25-55.85%
Jan 25-60.93%
Jan 25-64.09%
Jan 25-60.46%
Dec 24-69.61%
Dec 24-76.91%
Dec 24-73.3%
Dec 24-67.02%
Nov 24-80.89%
Nov 24-81.45%
Nov 24-72.18%
Nov 24-66.08%
Nov 24-59.26%
Oct 24-56.94%
Oct 24-52.8%
Price to Sales
020406080med 12.2Nov 24Feb 25Jun 25Sep 25Jan 26Apr 26Aug 26
APRE Price to Sales by quarter
PeriodPrice to Sales
Aug 2642.33
Jul 2640.36
Jul 2641.14
Jul 2646.18
Jul 2648.49
Jul 2648.23
Jun 2651.42
Jun 2646.54
Jun 2644.66
Jun 2648.26
May 2658.1
May 2661.84
May 2660.54
May 2626.85
May 2622.41
Apr 2625.48
Apr 2627.4
Apr 2625.12
Apr 2619.6
Mar 2618.71
Mar 2620.88
Mar 269.64
Mar 2611.79
Feb 2612.01
Feb 269.93
Feb 267.98
Feb 269.04
Jan 2610.43
Jan 2610.88
Jan 2611.66
Jan 2612.38
Jan 2611.18
Dec 2512.84
Dec 2512.19
Dec 2512.25
Dec 2513.89
Nov 2516.51
Nov 2515.33
Nov 2515.85
Nov 258.9
Oct 2510.13
Oct 2510.13
Oct 2511.36
Oct 2510.27
Oct 2510.85
Sep 2510.56
Sep 2510.42
Sep 2511.14
Sep 2511.21
Aug 2511.36
Aug 2511.94
Aug 2512.22
Aug 257.93
Aug 257.75
Jul 258.82
Jul 257.75
Jul 258.07
Jul 258.12
Jun 257.84
Jun 257.65
Jun 258.59
Jun 258.17
May 258.12
May 257.79
May 258.68
May 256.42
May 257.33
Apr 256.3
Apr 255.94
Apr 256.14
Apr 256.74
Mar 258.28
Mar 2510.83
Mar 2510.88
Mar 2510.56
Feb 2511.46
Feb 2511.87
Feb 2516.27
Feb 2517.35
Jan 2517.72
Jan 2519.03
Jan 2517.45
Jan 2516.58
Jan 2517.58
Dec 2415.27
Dec 2413.82
Dec 2414.5
Dec 2415.86
Nov 2413.14
Nov 2413.05
Nov 2414.73
Nov 2416.09
Nov 2418.24
Oct 2418.99
Oct 2420.48
Oct 2412.1
Oct 2412.1
Sep 2412.8
Sep 2414.57
Sep 2414.66
Price to Book
00.511.5med 0.64Dec 24Apr 25Jul 25Oct 25Feb 26May 26Sep 26
APRE Price to Book by quarter
PeriodPrice to Book
Sep 261.08
Sep 261.1
Aug 261.17
Aug 260.89
Aug 260.95
Aug 260.12
Jul 260.11
Jul 260.11
Jul 260.13
Jul 260.13
Jul 260.13
Jun 260.14
Jun 260.13
Jun 260.12
Jun 260.13
May 260.16
May 260.17
May 260.17
May 260.61
May 260.51
Apr 260.57
Apr 260.62
Apr 260.57
Apr 260.44
Mar 260.42
Mar 260.47
Mar 260.4
Mar 260.49
Feb 260.5
Feb 260.41
Feb 260.33
Feb 260.38
Jan 260.44
Jan 260.45
Jan 260.49
Jan 260.52
Jan 260.47
Dec 250.54
Dec 250.51
Dec 250.51
Dec 250.58
Nov 250.69
Nov 250.64
Nov 250.66
Nov 250.56
Oct 250.63
Oct 250.63
Oct 250.71
Oct 250.64
Oct 250.68
Sep 250.66
Sep 250.65
Sep 250.7
Sep 250.7
Aug 250.71
Aug 250.75
Aug 250.77
Aug 250.66
Aug 250.64
Jul 250.73
Jul 250.64
Jul 250.67
Jul 250.67
Jun 250.65
Jun 250.63
Jun 250.71
Jun 250.67
May 250.67
May 250.64
May 250.72
May 250.5
May 250.57
Apr 250.49
Apr 250.46
Apr 250.48
Apr 250.52
Mar 250.64
Mar 250.65
Mar 250.65
Mar 250.63
Feb 250.68
Feb 250.71
Feb 250.97
Feb 251.04
Jan 251.06
Jan 251.14
Jan 251.04
Jan 250.99
Jan 251.05
Dec 240.91
Dec 240.83
Dec 240.87
Dec 240.95
Nov 240.78
Nov 240.78
Nov 240.88
Nov 240.96
Nov 240.87
Oct 240.9
Oct 240.97
Aprea Therapeutics, Inc.
APRE
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News: APRE

Aprea Therapeutics to Present at H.C. Wainwright 28th Annual Global Investment Conference

globenewswire.com · 10 Sep 2026

Aprea Therapeutics to Present at H.C. Wainwright 28th Annual Global Investment Conference

DOYLESTOWN, Pa., Sept. 10, 2026 (GLOBE NEWSWIRE) -- Aprea Therapeutics, Inc. (Nasdaq: APRE) (“Aprea”, or the “Company”), a clinical-stage precision medicine oncology company focused on the discovery and development of targeted therapies for patients with biomarker-defined cancers, today announced that Oren Gilad, Ph.D., President and Chief Executive Officer, will present at the H.C. Wainwright 28th Annual Global Investment Conference, to be held in person and virtually September 14-16, 2026.

Aprea Therapeutics Announces Expansion of Intellectual Property Portfolio for Precision Oncology Programs

globenewswire.com · 28 Aug 2026

Aprea Therapeutics Announces Expansion of Intellectual Property Portfolio for Precision Oncology Programs

Company Strengthens Global Intellectual Property Portfolio with 28 Issued and 30 Pending Patents Company Strengthens Global Intellectual Property Portfolio with 28 Issued and 30 Pending Patents

Aprea Therapeutics Announces Second Quarter 2026 Financial Results

globenewswire.com · 12 Aug 2026

Aprea Therapeutics Announces Second Quarter 2026 Financial Results

Enrollment in the ongoing Phase 1 dose escalation ACESOT-1051 trial of oral WEE1 inhibitor APR-1051 is accelerating as dose escalation advances

Lipocine Appoints Michael J. Grissinger to Board of Directors

prnewswire.com · 3 Aug 2026

Lipocine Appoints Michael J. Grissinger to Board of Directors

SALT LAKE CITY, Aug. 3, 2026 /PRNewswire/ -- Lipocine Inc. (NASDAQ: LPCN), a biopharmaceutical company leveraging its proprietary technology platform to augment therapeutics through effective oral delivery, today announced the appointment of Michael J. Grissinger to its Board of Directors, effective August 3, 2026.

Aprea Therapeutics Provides ACESOT-1051 Program Update for WEE1 Inhibitor APR-1051: Accelerating and Expanding Enrollment. Clinical Data Presentation Planned for Q4 2026

globenewswire.com · 30 Jul 2026

Aprea Therapeutics Provides ACESOT-1051 Program Update for WEE1 Inhibitor APR-1051: Accelerating and Expanding Enrollment. Clinical Data Presentation Planned for Q4 2026

Next clinical data update from the ongoing Phase 1 dose escalation ACESOT-1051 trial anticipated at a medical meeting in Q4 2026, providing a near-term opportunity to demonstrate continued clinical progress with APR-1051 Enrollment in ACESOT-1051 is accelerating as the Company advances dose escalation and amasses the clinical data needed to inform dose selection and subsequent development Aprea plans to advance APR-1051 in uterine serous carcinoma (USC) and Cyclin E–overexpressing platinum-resistant ovarian cancer (PROC) while also evaluating combination regimens with standard of care in HPV-positive head and neck cancer and colorectal cancer, utilizing dose levels that have shown single-agent activity and cleared safety review The expanded development strategy builds on emerging single-agent activity and positions APR-1051 across biomarker-defined indications where WEE1 inhibition may address significant unmet medical need DOYLESTOWN, Pa., July 30, 2026 (GLOBE NEWSWIRE) -- Aprea Therapeutics, Inc. (Nasdaq: APRE) (“Aprea”, or the “Company”), a clinical-stage precision medicine oncology company focused on the discovery and development of targeted therapies for patients with biomarker-defined cancers, today provided an update on the ongoing Phase 1 dose escalation ACESOT-1051 trial of its oral WEE1 inhibitor APR-1051.

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