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Zymeworks Inc.

$26.74 +$0.12 (+0.46%)
NASDAQ · 14 Sep 2026 15:45 UTC
Previous Close
$26.24
Day Range
$26.23$26.86
Year Range
$15.49$31.34
Market Cap
1.97B
AVG Volume
646.26K
Trailing/Forward PE
-13.28/20.38
PEG ratio
1.32
Dividend Yield
-
Next Earnings Date
2026-11-05
Primary Exchange
NASDAQUS
Revenue (USD)
0200M400M600M2016201720182019202020212022202320242025
ZYME Revenue (USD) by year
PeriodRevenue (USD)
2025105.97M
202476.3M
202376.01M
2022412.48M
202126.68M
202038.95M
201929.54M
201853.02M
201751.76M
201611.01M
Net Income (USD)
-300M-200M-100M0100M200M2016201720182019202020212022202320242025
ZYME Net Income (USD) by year
PeriodNet Income (USD)
2025-81.13M
2024-122.69M
2023-118.67M
2022124.34M
2021-211.84M
2020-180.55M
2019-145.44M
2018-36.56M
2017-10.41M
2016-33.81M
Operating Income (USD)
-300M-200M-100M0100M200M2016201720182019202020212022202320242025
ZYME Operating Income (USD) by year
PeriodOperating Income (USD)
2025-92.55M
2024-137.11M
2023-138.05M
2022130.53M
2021-215.63M
2020-187.47M
2019-151.3M
2018-33.13M
2017-9M
2016-37.86M
EBITDA (USD)
-300M-200M-100M0100M200M2016201720182019202020212022202320242025
ZYME EBITDA (USD) by year
PeriodEBITDA (USD)
2025-75.2M
2024-94.12M
2023-118.15M
2022137.53M
2021-210.49M
2020-182.23M
2019-145.21M
2018-30.58M
2017-6.23M
2016-38.32M
Cash Flows (USD)
-300M-200M-100M0100M200M2016201720182019202020212022202320242025
ZYME Cash Flows (USD) by year
PeriodCash Flows (USD)
2025-34.93M
2024-113.11M
2023-122.38M
2022122.55M
2021-204.45M
2020-157.67M
2019-95.73M
201820.76M
2017-2.9M
2016-40.71M
EPS (USD)
-6-4-2022016201720182019202020212022202320242025
ZYME EPS (USD) by year
PeriodEPS (USD)
2025-1.08
2024-1.61
2023-1.73
20221.78
2021-4.09
2020-3.58
2019-3.68
2018-1.35
2017-0.69
2016-1.7
Expenses (USD)
02.5B5B7.5B10BR&DSG&ACapex2016201720182019202020212022202320242025
ZYME Expenses (USD) by year
PeriodExpenses (USD)
2025198.94M
2024184.69M
2023218.13M
2022295.94M
2021254.67M
2020232.75M
20198.02B
201889.56M
201763.42M
201654.83M
Cash & Debt (USD)
0200M400M600MCashLong Term Debt2016201720182019202020212022202320242025
ZYME Cash & Debt (USD) by year
PeriodCash & Debt (USD)
2025228.8M
2024225.78M
2023374.33M
2022492.23M
2021252.61M
2020426.35M
2019298.9M
2018200.16M
201787.8M
201640.26M
Debt ratios
00.511.52019202020212022202320242025
ZYME Debt ratios by year
PeriodDebt ratios
20251.4
20240.73
20230.93
20221.16
20210.39
20201.15
20191.33
Margins
-800%-600%-400%-200%0%200%2016201720182019202020212022202320242025
ZYME Margins by year
PeriodMargins
202598.4%
2024100%
2023-11.59%
202249.46%
2021-648.01%
2020-337.29%
2019-292.3%
2018-7.37%
201721.42%
2016-222.93%
Return on Capital
-400%-200%0%200%2016201720182019202020212022202320242025
ZYME Return on Capital by year
PeriodReturn on Capital
2025-30.22%
2024-36.22%
2023-25.53%
202225.22%
2021-85.05%
2020-44.05%
2019-59.2%
2018-20.25%
2017-8.94%
2016-375.57%
Shares Outstanding
020M40M60M80M2016201720182019202020212022202320242025
ZYME Shares Outstanding by year
PeriodShares Outstanding
202575.34M
202475.85M
202370.83M
202266.51M
202151.84M
202051.14M
201943.48M
201831.97M
201725.38M
201619.7M
Book Value Per Share (USD)
02.557.5102016201720182019202020212022202320242025
ZYME Book Value Per Share (USD) by year
PeriodBook Value Per Share (USD)
20253.56
20244.47
20236.56
20227.41
20214.8
20208.02
20195.65
20185.65
20174.59
20160.46
Total Assets (USD)
0200M400M600M800M2016201720182019202020212022202320242025
ZYME Total Assets (USD) by year
PeriodTotal Assets (USD)
2025346.53M
2024463.09M
2023580.88M
2022648.73M
2021389.13M
2020538.38M
2019368.2M
2018244.36M
2017131.96M
201694M
Employee Count
01002003002022202320242025
ZYME Employee Count by year
PeriodEmployee Count
2025264
2024280
2023272
2022291
PE Ratio
23456med 3.19Mar 23May 23Jul 23Sep 23Nov 23Jan 24Mar 24
ZYME PE Ratio by year
PeriodPE Ratio
Mar 244.26
Feb 244.07
Feb 244.1
Feb 243.8
Feb 243.75
Jan 243.55
Jan 243.37
Jan 243.71
Jan 243.6
Dec 233.54
Dec 233.35
Dec 233.1
Dec 233.17
Dec 233.12
Nov 232.78
Nov 232.79
Nov 232.49
Nov 232.69
Oct 232.4
Oct 232.6
Oct 232.35
Oct 232.31
Sep 232.29
Sep 232.31
Sep 232.46
Sep 232.57
Sep 232.71
Aug 232.78
Aug 232.68
Aug 232.59
Aug 232.86
Jul 232.81
Jul 233.04
Jul 233.05
Jul 233.19
Jun 233.34
Jun 233.14
Jun 233.14
Jun 233.29
Jun 233.35
May 233.19
May 233.78
May 233.81
May 234.62
Apr 234.49
Apr 235.26
Apr 235.31
Apr 235.02
Mar 234.84
Mar 234.39
Mar 234.47
Mar 234.24
Free Cash Flow Yield
-15%-10%-5%0%med -4.68%Dec 24Apr 25Jul 25Oct 25Feb 26May 26Sep 26
ZYME Free Cash Flow Yield by year
PeriodFree Cash Flow Yield
Sep 26-6.27%
Sep 26-5.63%
Aug 26-5.82%
Aug 26-5.74%
Aug 26-6.55%
Aug 26-6.99%
Jul 26-4.69%
Jul 26-4.51%
Jul 26-4.26%
Jul 26-3.98%
Jul 26-3.91%
Jun 26-4.26%
Jun 26-4.45%
Jun 26-4.5%
Jun 26-4.28%
May 26-4.1%
May 26-4.02%
May 26-4.3%
May 26-4.31%
May 26-1.74%
Apr 26-1.65%
Apr 26-1.67%
Apr 26-1.76%
Apr 26-1.8%
Mar 26-1.92%
Mar 26-1.99%
Mar 26-2.03%
Mar 26-1.93%
Feb 26-3.75%
Feb 26-3.85%
Feb 26-3.87%
Feb 26-3.85%
Jan 26-3.88%
Jan 26-3.76%
Jan 26-3.72%
Jan 26-3.77%
Jan 26-3.28%
Dec 25-3.25%
Dec 25-3.21%
Dec 25-3.43%
Dec 25-3.27%
Nov 25-3.27%
Nov 25-3.64%
Nov 25-4.72%
Nov 25-5.31%
Oct 25-2.87%
Oct 25-3.09%
Oct 25-2.98%
Oct 25-3.03%
Oct 25-3.23%
Sep 25-3.3%
Sep 25-3.37%
Sep 25-3.48%
Sep 25-3.64%
Aug 25-3.7%
Aug 25-3.63%
Aug 25-3.81%
Aug 25-4.56%
Aug 25-8.31%
Jul 25-7.84%
Jul 25-7.33%
Jul 25-7.83%
Jul 25-8.01%
Jun 25-8.38%
Jun 25-8.37%
Jun 25-8.24%
Jun 25-8.29%
May 25-9.14%
May 25-9.05%
May 25-8.92%
May 25-9.24%
May 25-11.51%
Apr 25-11.86%
Apr 25-12.93%
Apr 25-14.03%
Apr 25-13.62%
Mar 25-12.06%
Mar 25-11.72%
Mar 25-12.17%
Mar 25-12.43%
Feb 25-5.79%
Feb 25-5.39%
Feb 25-5.17%
Feb 25-5.44%
Jan 25-5.32%
Jan 25-5.32%
Jan 25-5.59%
Jan 25-5.87%
Jan 25-5.17%
Dec 24-5.35%
Dec 24-5.49%
Dec 24-6.17%
Dec 24-5.45%
Nov 24-5.51%
Nov 24-5.43%
Nov 24-5.04%
Nov 24-4.67%
Nov 24-5.84%
Oct 24-9.72%
Oct 24-9.32%
Price to Sales
0204060med 15.09Dec 24Apr 25Jul 25Oct 25Feb 26May 26Sep 26
ZYME Price to Sales by year
PeriodPrice to Sales
Sep 2651.59
Sep 2657.39
Aug 2655.58
Aug 2656.37
Aug 2649.39
Aug 2646.28
Jul 2620.16
Jul 2621.01
Jul 2622.23
Jul 2623.78
Jul 2624.18
Jun 2622.19
Jun 2621.26
Jun 2621.02
Jun 2622.09
May 2623.09
May 2623.53
May 2621.99
May 2621.95
May 2618.92
Apr 2619.98
Apr 2619.76
Apr 2618.71
Apr 2618.34
Mar 2617.19
Mar 2616.58
Mar 2616.27
Mar 2617.12
Feb 2613.12
Feb 2612.8
Feb 2612.73
Feb 2612.8
Jan 2612.69
Jan 2613.09
Jan 2613.22
Jan 2613.05
Jan 2615
Dec 2515.14
Dec 2515.34
Dec 2514.36
Dec 2515.04
Nov 2515.05
Nov 2513.53
Nov 2510.43
Nov 259.27
Oct 2511.71
Oct 2510.88
Oct 2511.28
Oct 2511.07
Oct 2510.39
Sep 2510.18
Sep 259.96
Sep 259.65
Sep 259.23
Aug 259.08
Aug 259.26
Aug 258.8
Aug 257.37
Aug 2510.12
Jul 2510.73
Jul 2511.47
Jul 2510.74
Jul 2510.5
Jun 2510.04
Jun 2510.05
Jun 2510.2
Jun 2510.14
May 259.2
May 259.29
May 259.43
May 259.1
May 2512.88
Apr 2512.49
Apr 2511.46
Apr 2510.57
Apr 2510.88
Mar 2512.3
Mar 2512.64
Mar 2512.18
Mar 2511.93
Feb 2516.4
Feb 2517.61
Feb 2518.37
Feb 2517.48
Jan 2517.87
Jan 2517.86
Jan 2516.99
Jan 2516.18
Jan 2518.37
Dec 2417.75
Dec 2417.31
Dec 2415.4
Dec 2417.44
Nov 2417.25
Nov 2417.49
Nov 2418.84
Nov 2420.35
Nov 2416.25
Oct 2415.75
Oct 2416.42
EV/EBITDA
0123med 1.25Mar 23May 23Jul 23Sep 23Nov 23Jan 24Mar 24
ZYME EV/EBITDA by year
PeriodEV/EBITDA
Mar 242.74
Feb 242.56
Feb 242.58
Feb 242.31
Feb 242.26
Jan 242.07
Jan 241.91
Jan 242.22
Jan 242.12
Dec 232.07
Dec 231.89
Dec 231.66
Dec 231.72
Dec 231.68
Nov 231.36
Nov 231.37
Nov 231.09
Nov 230.94
Oct 230.67
Oct 230.86
Oct 230.62
Oct 230.59
Sep 230.57
Sep 230.59
Sep 230.73
Sep 230.83
Sep 230.96
Aug 231.03
Aug 230.93
Aug 230.85
Aug 230.98
Jul 230.94
Jul 231.16
Jul 231.17
Jul 231.3
Jun 231.44
Jun 231.24
Jun 231.25
Jun 231.39
Jun 231.45
May 231.29
May 231.85
May 231.88
May 230.8
Apr 230.69
Apr 231.38
Apr 231.43
Apr 231.17
Mar 231
Mar 230.59
Mar 230.67
Mar 230.46
Price/Operating Cashflow
0200400600med 5.74Jun 19Sep 19Jan 20Apr 23Aug 23Nov 23Mar 24
ZYME Price/Operating Cashflow by year
PeriodPrice/Operating Cashflow
Mar 244.71
Feb 244.49
Feb 244.52
Feb 244.2
Feb 244.14
Jan 243.91
Jan 243.72
Jan 244.09
Jan 243.97
Dec 233.91
Dec 233.7
Dec 233.42
Dec 233.5
Dec 233.44
Nov 233.06
Nov 233.08
Nov 232.74
Nov 233.21
Oct 232.88
Oct 233.11
Oct 232.81
Oct 232.77
Sep 232.74
Sep 232.77
Sep 232.94
Sep 233.08
Sep 233.24
Aug 233.33
Aug 233.21
Aug 233.1
Aug 234.6
Jul 234.53
Jul 234.9
Jul 234.92
Jul 235.14
Jun 235.38
Jun 235.05
Jun 235.06
Jun 235.31
Jun 235.4
May 235.14
May 236.08
May 236.14
May 234.26
Apr 234.14
Apr 234.84
Apr 234.89
Apr 234.63
Mar 234.46
Mar 234.04
Mar 234.12
Mar 233.91
Feb 20386.07
Feb 20420.97
Feb 20452.47
Feb 20431.53
Jan 20411.63
Jan 20447.28
Jan 20463.32
Jan 20423.7
Jan 20432.57
Dec 19421.15
Dec 19426.91
Dec 19396.16
Dec 19394.55
Nov 19411.16
Nov 19396.16
Nov 19340.88
Nov 19322.96
Nov 19430.74
Oct 19382.27
Oct 19364.43
Oct 19336.99
Oct 19314.85
Sep 19318.41
Sep 19337.61
Sep 19315.22
Sep 19357.79
Aug 19327.76
Aug 19307.46
Aug 19324.69
Aug 19302.3
Aug 19287.9
Jul 1937.95
Jul 1938.04
Jul 1937.59
Jul 1936.96
Jun 1934.45
Jun 1933.62
Jun 1932.11
Jun 1932.78
May 1929.77
May 1927.63
May 1928.22
May 1928.47
May 1930.13
Apr 1922.62
Apr 1921.22
Apr 1919.83
Apr 1921.12
Price to Book
0102030med 3.78Dec 24Apr 25Jul 25Oct 25Feb 26May 26Sep 26
ZYME Price to Book by year
PeriodPrice to Book
Sep 2623.83
Sep 2626.51
Aug 2625.68
Aug 2626.04
Aug 2622.81
Aug 2621.38
Jul 2610.01
Jul 2610.43
Jul 2611.04
Jul 2611.81
Jul 2612.01
Jun 2611.02
Jun 2610.56
Jun 2610.44
Jun 2610.97
May 2611.47
May 2611.69
May 2610.92
May 2610.9
May 267.47
Apr 267.88
Apr 267.8
Apr 267.39
Apr 267.24
Mar 266.78
Mar 266.54
Mar 266.42
Mar 266.76
Feb 265.51
Feb 265.38
Feb 265.35
Feb 265.38
Jan 265.33
Jan 265.5
Jan 265.56
Jan 265.48
Jan 266.3
Dec 256.36
Dec 256.45
Dec 256.03
Dec 256.32
Nov 256.32
Nov 255.69
Nov 254.38
Nov 253.9
Oct 254.3
Oct 254
Oct 254.14
Oct 254.07
Oct 253.82
Sep 253.74
Sep 253.66
Sep 253.54
Sep 253.39
Aug 253.34
Aug 253.4
Aug 253.23
Aug 252.71
Aug 252.91
Jul 253.08
Jul 253.3
Jul 253.09
Jul 253.02
Jun 252.88
Jun 252.89
Jun 252.93
Jun 252.91
May 252.64
May 252.67
May 252.71
May 252.62
May 252.9
Apr 252.81
Apr 252.58
Apr 252.38
Apr 252.45
Mar 252.77
Mar 252.85
Mar 252.74
Mar 252.69
Feb 252.78
Feb 252.99
Feb 253.11
Feb 252.96
Jan 253.03
Jan 253.03
Jan 252.88
Jan 252.74
Jan 253.11
Dec 243.01
Dec 242.93
Dec 242.61
Dec 242.96
Nov 242.92
Nov 242.96
Nov 243.19
Nov 243.45
Nov 242.75
Oct 242.43
Oct 242.54
Zymeworks Inc.
ZYME
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News: ZYME

Jupiter Topco LLC Buys New Position in Zymeworks Inc. $ZYME

defenseworld.net · 8 Sep 2026

Jupiter Topco LLC Buys New Position in Zymeworks Inc. $ZYME

Jupiter Topco LLC bought a new position in shares of Zymeworks Inc. (NASDAQ: ZYME) in the undefined quarter, according to the company in its most recent disclosure with the Securities and Exchange Commission. The firm bought 18,200 shares of the company's stock, valued at approximately $476,000. A number of other hedge funds have

Zymeworks: Transitioning Into A Royalty-Driven Biopharma Platform Post Ziihera Approval

seekingalpha.com · 27 Aug 2026

Zymeworks: Transitioning Into A Royalty-Driven Biopharma Platform Post Ziihera Approval

Zymeworks Inc. is transitioning from a development-stage biotech to a royalty-driven, revenue-generating platform following zanidatamab's FDA approval. Zanidatamab's first-line HER2+ gastroesophageal cancer approval expands the eligible patient population and unlocks a $250M milestone plus 10–20% tiered royalties. ZYME's near-term upside hinges on commercial execution, label expansions, and integrating durable cash-flow assets like YUPELRI from the pending Theravance acquisition.

Bank of America Corp DE Raises Position in Zymeworks Inc. $ZYME

defenseworld.net · 27 Aug 2026

Bank of America Corp DE Raises Position in Zymeworks Inc. $ZYME

Bank of America Corp DE lifted its stake in Zymeworks Inc. (NASDAQ: ZYME) by 164.5% during the undefined quarter, according to the company in its most recent disclosure with the Securities and Exchange Commission. The firm owned 236,754 shares of the company's stock after buying an additional 147,230 shares during the period. Bank

JAZZ Secures FDA Nod for Expanded Use of Ziihera in Gastric Cancer

zacks.com · 26 Aug 2026

JAZZ Secures FDA Nod for Expanded Use of Ziihera in Gastric Cancer

Jazz Pharmaceuticals' Ziihera wins FDA approval for first-line HER2-positive GEA, expanding its market and showing strong progression-free and survival benefits.

Deutsche Bank AG Buys Shares of 397,190 Zymeworks Inc. $ZYME

defenseworld.net · 24 Aug 2026

Deutsche Bank AG Buys Shares of 397,190 Zymeworks Inc. $ZYME

Deutsche Bank AG purchased a new stake in Zymeworks Inc. (NASDAQ: ZYME) in the second quarter, according to the company in its most recent 13F filing with the Securities and Exchange Commission (SEC). The firm purchased 397,190 shares of the company's stock, valued at approximately $10,383,000. Deutsche Bank AG owned approximately 0.54% of

TBPH Meets Q2 Earnings Estimates, to be Acquired by Zymeworks

zacks.com · 11 Aug 2026

TBPH Meets Q2 Earnings Estimates, to be Acquired by Zymeworks

Theravance's Q2 earnings match estimates. Cost cuts and a $929 million Zymeworks deal follow ampreloxetine's discontinuation.

Zymeworks Inc. (ZYME) Reports Q2 Loss, Beats Revenue Estimates

zacks.com · 6 Aug 2026

Zymeworks Inc. (ZYME) Reports Q2 Loss, Beats Revenue Estimates

Zymeworks Inc. (ZYME) came out with a quarterly loss of $0.62 per share versus the Zacks Consensus Estimate of a loss of $0.56. This compares to earnings of $0.03 per share a year ago.

Zymeworks Provides Corporate Update and Reports Second Quarter 2026 Financial Results

globenewswire.com · 6 Aug 2026

Zymeworks Provides Corporate Update and Reports Second Quarter 2026 Financial Results

August 25, 2026 U.S. PDUFA target action date for zanidatamab has potential to unlock a $250 million U.S. approval milestone and up to $190 million in potential additional global regulatory milestones Acquisition of Theravance Biopharma, Inc. expected to close in 2H 2026, adding durable commercial cash flows and expanding Zymeworks' diversified revenue base Continued advancement of R&D pipeline across wholly-owned and partnered programs Repurchased $49.4 million of common shares as of August 4, 2026 under the newly authorized 2026 share repurchase program Strong balance sheet with $322.5 million in cash, cash equivalents and marketable securities as of June 30, 2026 VANCOUVER, British Columbia, Aug. 06, 2026 (GLOBE NEWSWIRE) -- Zymeworks Inc. (Nasdaq: ZYME), a biotechnology company managing a portfolio of licensed healthcare assets, while developing a diverse pipeline of novel, multifunctional biotherapeutics, today reported financial results for the second quarter ended June 30, 2026 and provided a summary of recent business highlights. In light of the previously announced proposed acquisition of Theravance Biopharma, the Company has elected not to host a second quarter earnings conference call after release of its financial results.

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