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Tyra Biosciences, Inc.

$22.03 -$4.76 (-17.77%)
NASDAQ · 11 Sep 2026 20:00 UTC
Previous Close
$23.54
Day Range
$21.83$23.96
Year Range
$11.82$40.65
Market Cap
1.31B
AVG Volume
844.87K
Trailing/Forward PE
-9.18/-
PEG ratio
-1.07
Dividend Yield
-
Next Earnings Date
2026-11-04
Primary Exchange
NASDAQUS
Net Income (USD)
-150M-100M-50M0202020212022202320242025
TYRA Net Income (USD) by year
PeriodNet Income (USD)
2025-119.95M
2024-86.48M
2023-69.13M
2022-55.33M
2021-26.29M
2020-9.34M
Operating Income (USD)
-150M-100M-50M0202020212022202320242025
TYRA Operating Income (USD) by year
PeriodOperating Income (USD)
2025-132.76M
2024-104.2M
2023-79.94M
2022-58.92M
2021-26.29M
2020-9.3M
EBITDA (USD)
-150M-100M-50M0202020212022202320242025
TYRA EBITDA (USD) by year
PeriodEBITDA (USD)
2025-119.4M
2024-85.96M
2023-68.75M
2022-55.03M
2021-26.16M
2020-9.29M
Cash Flows (USD)
-100M-75M-50M-25M0202020212022202320242025
TYRA Cash Flows (USD) by year
PeriodCash Flows (USD)
2025-95.28M
2024-70.44M
2023-50.91M
2022-50.84M
2021-24.41M
2020-8.07M
EPS (USD)
-3-2-10202020212022202320242025
TYRA EPS (USD) by year
PeriodEPS (USD)
2025-2.01
2024-1.51
2023-1.61
2022-0.52
2021-1.3
2020-2.6
Expenses (USD)
050M100M150MR&DSG&ACapex202020212022202320242025
TYRA Expenses (USD) by year
PeriodExpenses (USD)
2025132.9M
2024104.62M
202380.72M
202259.48M
202126.95M
20209.61M
Cash & Debt (USD)
0100M200M300M400MCashLong Term DebtShort Term Debt202020212022202320242025
TYRA Cash & Debt (USD) by year
PeriodCash & Debt (USD)
2025256M
2024341.44M
2023203.47M
2022251.21M
2021302.18M
202015.22M
Debt ratios
00.511.5202320242025
TYRA Debt ratios by year
PeriodDebt ratios
20250.76
20241.42
20231.24
Return on Capital
-50%0%50%100%202020212022202320242025
TYRA Return on Capital by year
PeriodReturn on Capital
2025-46.28%
2024-25.2%
2023-33.85%
2022-21.46%
2021-8.71%
202068.46%
Shares Outstanding
020M40M60M202020212022202320242025
TYRA Shares Outstanding by year
PeriodShares Outstanding
202559.6M
202458.87M
202342.97M
202242.21M
202141.3M
202022.48M
Book Value Per Share (USD)
-202468202020212022202320242025
TYRA Book Value Per Share (USD) by year
PeriodBook Value Per Share (USD)
20254.35
20245.83
20234.75
20226.11
20217.31
2020-0.61
Total Assets (USD)
0100M200M300M400M202020212022202320242025
TYRA Total Assets (USD) by year
PeriodTotal Assets (USD)
2025282.61M
2024363.56M
2023225.86M
2022266.18M
2021306.7M
202016.01M
Employee Count
025507510020212022202320242025
TYRA Employee Count by year
PeriodEmployee Count
202587
202460
202349
202238
202125
Free Cash Flow Yield
-20%-15%-10%-5%0%med -7.08%Dec 24Apr 25Jul 25Oct 25Feb 26May 26Sep 26
TYRA Free Cash Flow Yield by year
PeriodFree Cash Flow Yield
Sep 26-7.56%
Sep 26-5.81%
Aug 26-6.68%
Aug 26-6.39%
Aug 26-6.59%
Aug 26-6.28%
Jul 26-5.21%
Jul 26-5.42%
Jul 26-5.17%
Jul 26-5.07%
Jul 26-5.42%
Jun 26-5.21%
Jun 26-5.86%
Jun 26-6.15%
Jun 26-6.23%
May 26-4.97%
May 26-5.11%
May 26-4.48%
May 26-4.66%
May 26-4.7%
Apr 26-4.25%
Apr 26-4.5%
Apr 26-4.53%
Apr 26-4.04%
Mar 26-4.41%
Mar 26-4.3%
Mar 26-4.41%
Mar 26-4.56%
Feb 26-4.59%
Feb 26-4.84%
Feb 26-5.46%
Feb 26-4.93%
Jan 26-4.96%
Jan 26-5.03%
Jan 26-5.31%
Jan 26-5.21%
Jan 26-5.7%
Dec 25-5.89%
Dec 25-5.99%
Dec 25-6.75%
Dec 25-7.11%
Nov 25-6.77%
Nov 25-7.24%
Nov 25-9.72%
Nov 25-10.67%
Oct 25-9.19%
Oct 25-10.23%
Oct 25-10.04%
Oct 25-10.77%
Oct 25-10.66%
Sep 25-11.23%
Sep 25-11.65%
Sep 25-11.63%
Sep 25-11.51%
Aug 25-11.49%
Aug 25-12.44%
Aug 25-13.57%
Aug 25-11.89%
Aug 25-11.98%
Jul 25-11.24%
Jul 25-11.96%
Jul 25-12.11%
Jul 25-12.43%
Jun 25-13.66%
Jun 25-13.47%
Jun 25-11.92%
Jun 25-11.78%
May 25-13.66%
May 25-13.38%
May 25-12.44%
May 25-12.32%
May 25-11.02%
Apr 25-11.92%
Apr 25-13.41%
Apr 25-15.03%
Apr 25-15.46%
Mar 25-12.25%
Mar 25-10.32%
Mar 25-9.6%
Mar 25-10.09%
Feb 25-9.42%
Feb 25-8.38%
Feb 25-8.37%
Feb 25-8.71%
Jan 25-7.63%
Jan 25-6.95%
Jan 25-6.82%
Jan 25-7.26%
Jan 25-7.06%
Dec 24-7.84%
Dec 24-7.88%
Dec 24-7.39%
Dec 24-7.02%
Nov 24-7.04%
Nov 24-6.97%
Nov 24-7.17%
Nov 24-6.85%
Nov 24-6.68%
Oct 24-4.99%
Oct 24-4.01%
Price to Book
0246810med 2.75Dec 24Apr 25Jul 25Oct 25Feb 26May 26Sep 26
TYRA Price to Book by year
PeriodPrice to Book
Sep 264.11
Sep 265.35
Aug 264.65
Aug 264.86
Aug 264.72
Aug 264.95
Jul 265.08
Jul 264.88
Jul 265.12
Jul 265.22
Jul 264.88
Jun 265.08
Jun 264.51
Jun 264.3
Jun 264.24
May 265.32
May 265.17
May 265.9
May 267.89
May 267.83
Apr 268.64
Apr 268.18
Apr 268.11
Apr 269.11
Mar 268.35
Mar 268.54
Mar 268.33
Mar 268.06
Feb 267.09
Feb 266.72
Feb 265.95
Feb 266.59
Jan 266.56
Jan 266.46
Jan 266.12
Jan 266.23
Jan 265.7
Dec 255.52
Dec 255.43
Dec 254.81
Dec 254.57
Nov 254.8
Nov 254.49
Nov 253.35
Nov 253.05
Oct 253.12
Oct 252.8
Oct 252.86
Oct 252.66
Oct 252.69
Sep 252.56
Sep 252.46
Sep 252.47
Sep 252.49
Aug 252.5
Aug 252.31
Aug 252.11
Aug 251.92
Aug 251.9
Jul 252.03
Jul 251.91
Jul 251.88
Jul 251.83
Jun 251.67
Jun 251.69
Jun 251.91
Jun 251.93
May 251.67
May 251.7
May 251.83
May 251.85
May 251.86
Apr 251.72
Apr 251.53
Apr 251.37
Apr 251.33
Mar 251.68
Mar 251.74
Mar 251.87
Mar 251.78
Feb 251.9
Feb 252.14
Feb 252.14
Feb 252.06
Jan 252.35
Jan 252.58
Jan 252.63
Jan 252.47
Jan 252.54
Dec 242.29
Dec 242.28
Dec 242.43
Dec 242.56
Nov 242.55
Nov 242.57
Nov 242.5
Nov 242.62
Nov 242.56
Oct 243.42
Oct 244.26
Tyra Biosciences, Inc.
TYRA
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News: TYRA

INVESTOR ALERT: Pomerantz Law Firm Investigates Claims On Behalf of Investors of Tyra Biosciences, Inc. - TYRA

gurufocus.com · 10 Sep 2026

INVESTOR ALERT: Pomerantz Law Firm Investigates Claims On Behalf of Investors of Tyra Biosciences, Inc. - TYRA

INVESTOR ALERT: Pomerantz Law Firm Investigates Claims On Behalf of Investors of Tyra Biosciences, Inc. - TYRAPR NewswireNEW YORK, Sept. 10, 2026NEW YORK, Sept.

INVESTOR ALERT: Pomerantz Law Firm Investigates Claims On Behalf of Investors of Tyra Biosciences, Inc. - TYRA

prnewswire.com · 10 Sep 2026

INVESTOR ALERT: Pomerantz Law Firm Investigates Claims On Behalf of Investors of Tyra Biosciences, Inc. - TYRA

NEW YORK, Sept. 10, 2026 /PRNewswire/ -- Pomerantz LLP is investigating claims on behalf of investors of Tyra Biosciences, Inc. ("Tyra" or the "Company") (NASDAQ: TYRA).

Tyra Biosciences, Inc. (TYRA) Discusses Initial SURF302 Results on Oral Dabogratinib for Intermediate Risk NMIBC Transcript

seekingalpha.com · 10 Sep 2026

Tyra Biosciences, Inc. (TYRA) Discusses Initial SURF302 Results on Oral Dabogratinib for Intermediate Risk NMIBC Transcript

Tyra Biosciences, Inc. (TYRA) Discusses Initial SURF302 Results on Oral Dabogratinib for Intermediate Risk NMIBC Transcript

Why Is Tyra Biosciences Stock Sinking Wednesday?

benzinga.com · 9 Sep 2026

Why Is Tyra Biosciences Stock Sinking Wednesday?

Tyra Biosciences Inc. (NASDAQ:TYRA) stock is trading lower on Wednesday after the company shared initial results from its Phase 2 SURF302 trial evaluating oral dabogratinib, delivering clinical proof of concept and identifying a 60 mg once-daily dose to support planned registrational studies.

Tyra Plummets To 10-Month Low On Mixed Bladder Cancer Results

investors.com · 9 Sep 2026

Tyra Plummets To 10-Month Low On Mixed Bladder Cancer Results

Tyra stock plummeted to a 10-month low Wednesday on mixed test results for its experimental bladder cancer treatment.

Tyra Biosciences Stock Plunges 22% as Bladder Cancer Pill Fails to Impress

barrons.com · 9 Sep 2026

Tyra Biosciences Stock Plunges 22% as Bladder Cancer Pill Fails to Impress

Tyra Biosciences and Johnson & Johnson are pursuing their own approaches to treating a common, early-stage form of bladder cancer.

Tyra Biosciences Reports Initial Phase 2 SURF302 Results Supporting the First Potential Oral Innovation in LG IR NMIBC with Dabogratinib

prnewswire.com · 9 Sep 2026

Tyra Biosciences Reports Initial Phase 2 SURF302 Results Supporting the First Potential Oral Innovation in LG IR NMIBC with Dabogratinib

CARLSBAD, Calif., Sept. 9, 2026 /PRNewswire/ -- Tyra Biosciences, Inc. (Nasdaq: TYRA), a clinical-stage biotechnology company focused on developing next-generation precision medicines that target large opportunities in Fibroblast Growth Factor Receptor (FGFR) biology, today announced initial results from SURF302, its Phase 2 study evaluating oral dabogratinib in patients with FGFR3-altered low-grade intermediate-risk non-muscle invasive bladder cancer (LG IR NMIBC). The study provided clinical proof of concept for selective oral FGFR3 inhibition and identified 60 mg once-daily (QD) as the potential dose supporting TYRA's planned registrational adjuvant development strategy.

Tyra Biosciences to Present at the Cantor Global Healthcare Conference

prnewswire.com · 8 Sep 2026

Tyra Biosciences to Present at the Cantor Global Healthcare Conference

CARLSBAD, Calif., Sept. 8, 2026 /PRNewswire/ -- Tyra Biosciences, Inc. (Nasdaq: TYRA), a clinical-stage biotechnology company focused on developing next-generation precision medicines that target large opportunities in Fibroblast Growth Factor Receptor (FGFR) biology, today announced participation at the following investor conference: Cantor Global Healthcare Conference 2026 Format: Virtual fireside chat and one-on-one investor meetingsPresentation Date/Time: Wednesday, September 9, 2026 at 1:00 PM ETLocation: New York, NY A live webcast of the presentation can be accessed by visiting the "For Investors" page on the Tyra Biosciences  website  and will be available for replay following the event.

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