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Taysha Gene Therapies, Inc.

$5.02 -$0.23 (-4.38%)
NASDAQ · 11 Sep 2026 20:00 UTC
Previous Close
$5.16
Day Range
$4.98$5.26
Year Range
$2.71$7.3
Market Cap
1.61B
AVG Volume
2.87M
Trailing/Forward PE
-11.88/-
PEG ratio
-2.88
Dividend Yield
-
Next Earnings Date
2026-11-03
Primary Exchange
NASDAQUS
Revenue (USD)
05M10M15M20M202020212022202320242025
TSHA Revenue (USD) by year
PeriodRevenue (USD)
20259.77M
20248.33M
202315.45M
20222.5M
20210
20200
Net Income (USD)
-200M-150M-100M-50M0202020212022202320242025
TSHA Net Income (USD) by year
PeriodNet Income (USD)
2025-108.99M
2024-89.3M
2023-111.57M
2022-166.66M
2021-174.52M
2020-60.01M
Operating Income (USD)
-200M-150M-100M-50M0202020212022202320242025
TSHA Operating Income (USD) by year
PeriodOperating Income (USD)
2025-110.5M
2024-91.46M
2023-71.82M
2022-127.18M
2021-173.27M
2020-43M
EBITDA (USD)
-200M-150M-100M-50M0202020212022202320242025
TSHA EBITDA (USD) by year
PeriodEBITDA (USD)
2025-108.25M
2024-87.95M
2023-104.54M
2022-160.88M
2021-172.6M
2020-59.97M
Cash Flows (USD)
-150M-100M-50M0202020212022202320242025
TSHA Cash Flows (USD) by year
PeriodCash Flows (USD)
2025-93.83M
2024-81.6M
2023-80.39M
2022-113.69M
2021-138.6M
2020-36.81M
EPS (USD)
-6-4-20202020212022202320242025
TSHA EPS (USD) by year
PeriodEPS (USD)
2025-0.34
2024-0.38
2023-1.34
2022-3.8
2021-4.63
2020-2.74
Expenses (USD)
050M100M150M200MR&DSG&ACapex202020212022202320242025
TSHA Expenses (USD) by year
PeriodExpenses (USD)
2025120.42M
202495.33M
202392.53M
2022152.87M
2021194.82M
202049.08M
Cash & Debt (USD)
0100M200M300M400MCashLong Term Debt202020212022202320242025
TSHA Cash & Debt (USD) by year
PeriodCash & Debt (USD)
2025319.77M
2024139.04M
2023143.94M
202287.88M
2021149.1M
2020251.25M
Debt ratios
00.20.40.60.8202320242025
TSHA Debt ratios by year
PeriodDebt ratios
20250.65
20240.14
20230.17
Margins
0%25%50%75%100%2022202320242025
TSHA Margins by year
PeriodMargins
202594.01%
2024100%
202389.22%
202232.89%
Return on Capital
-20000%-15000%-10000%-5000%0%202020212022202320242025
TSHA Return on Capital by year
PeriodReturn on Capital
2025-44.14%
2024-124.85%
2023-148.88%
2022-17561.54%
2021-182.97%
2020-23.88%
Shares Outstanding
0100M200M300M400M202020212022202320242025
TSHA Shares Outstanding by year
PeriodShares Outstanding
2025319.71M
2024204.94M
2023186.96M
202256.39M
202138.11M
202037.76M
Book Value Per Share (USD)
02468202020212022202320242025
TSHA Book Value Per Share (USD) by year
PeriodBook Value Per Share (USD)
20250.77
20240.35
20230.4
20220.02
20212.5
20206.65
Total Assets (USD)
0100M200M300M400M202020212022202320242025
TSHA Total Assets (USD) by year
PeriodTotal Assets (USD)
2025343.32M
2024160.36M
2023172.73M
2022126.28M
2021213.96M
2020258.88M
Employee Count
050100150200202020212022202320242025
TSHA Employee Count by year
PeriodEmployee Count
202599
202473
202352
202265
2021178
202038
Free Cash Flow Yield
-40%-30%-20%-10%0%med -7.78%Dec 24Apr 25Jul 25Oct 25Feb 26May 26Sep 26
TSHA Free Cash Flow Yield by year
PeriodFree Cash Flow Yield
Sep 26-7.32%
Sep 26-6.56%
Aug 26-6.37%
Aug 26-6.03%
Aug 26-6.17%
Aug 26-4.8%
Jul 26-5.37%
Jul 26-5.7%
Jul 26-5.28%
Jul 26-4.96%
Jul 26-4.82%
Jun 26-4.96%
Jun 26-4.9%
Jun 26-5.51%
Jun 26-5.72%
May 26-5.36%
May 26-5.73%
May 26-5.28%
May 26-4.62%
May 26-4.64%
Apr 26-4.59%
Apr 26-4.56%
Apr 26-6.54%
Apr 26-6.72%
Mar 26-7.21%
Mar 26-6.67%
Mar 26-5.37%
Mar 26-5.27%
Feb 26-5.32%
Feb 26-5.13%
Feb 26-5.3%
Feb 26-5.23%
Jan 26-5.34%
Jan 26-5.17%
Jan 26-5.29%
Jan 26-4.84%
Jan 26-4.59%
Dec 25-4.13%
Dec 25-4.39%
Dec 25-4.16%
Dec 25-4.77%
Nov 25-5.09%
Nov 25-5.75%
Nov 25-5.84%
Nov 25-6.29%
Oct 25-5.58%
Oct 25-5.83%
Oct 25-5.87%
Oct 25-5.68%
Oct 25-5.82%
Sep 25-8.52%
Sep 25-9.79%
Sep 25-9.02%
Sep 25-8.24%
Aug 25-9.49%
Aug 25-9.23%
Aug 25-9.42%
Aug 25-11.48%
Aug 25-11.87%
Jul 25-11.78%
Jul 25-12.15%
Jul 25-11.82%
Jul 25-12.74%
Jun 25-13.11%
Jun 25-12.69%
Jun 25-12.29%
Jun 25-10.99%
May 25-11.52%
May 25-11.35%
May 25-11.56%
May 25-18.69%
May 25-15.43%
Apr 25-22.62%
Apr 25-32.11%
Apr 25-31.85%
Apr 25-32.64%
Mar 25-20.63%
Mar 25-24.28%
Mar 25-23.15%
Mar 25-22.75%
Feb 25-24.88%
Feb 25-18.42%
Feb 25-18.19%
Feb 25-16.95%
Jan 25-19.77%
Jan 25-19.51%
Jan 25-19.38%
Jan 25-16.85%
Jan 25-15.45%
Dec 24-16.95%
Dec 24-16.03%
Dec 24-14.33%
Dec 24-11.96%
Nov 24-9.15%
Nov 24-12.01%
Nov 24-14.4%
Nov 24-22.69%
Nov 24-22.24%
Oct 24-17.1%
Oct 24-16.52%
Price to Sales
0100200300400500med 128.39Dec 24Apr 25Jul 25Oct 25Feb 26May 26Sep 26
TSHA Price to Sales by year
PeriodPrice to Sales
Sep 26337.76
Sep 26376.78
Aug 26388.22
Aug 26409.75
Aug 26400.33
Aug 26321.93
Jul 26287.57
Jul 26270.89
Jul 26292.48
Jul 26311.13
Jul 26320.45
Jun 26311.13
Jun 26315.06
Jun 26280.21
Jun 26269.91
May 26288.07
May 26269.42
May 26292.48
May 26334.19
May 26207.08
Apr 26209.37
Apr 26210.35
Apr 26146.88
Apr 26142.96
Mar 26133.15
Mar 26143.94
Mar 26251.4
Mar 26255.88
Feb 26253.64
Feb 26263.16
Feb 26254.76
Feb 26258.12
Jan 26252.52
Jan 26260.92
Jan 26255.32
Jan 26278.84
Jan 26293.96
Dec 25326.43
Dec 25307.4
Dec 25324.19
Dec 25282.76
Nov 25265.4
Nov 25234.61
Nov 25231.25
Nov 25214.45
Oct 25182.52
Oct 25174.79
Oct 25173.69
Oct 25179.57
Oct 25175.16
Sep 25119.59
Sep 25104.14
Sep 25112.97
Sep 25123.64
Aug 25107.45
Aug 25110.39
Aug 25108.19
Aug 25101.4
Aug 2598.04
Jul 2598.79
Jul 2595.81
Jul 2598.42
Jul 2591.33
Jun 2588.72
Jun 2591.71
Jun 2594.69
Jun 25105.87
May 25101.03
May 25102.52
May 25100.65
May 2552.39
May 2563.45
Apr 2543.29
Apr 2530.5
Apr 2530.74
Apr 2530
Mar 2547.47
Mar 2540.33
Mar 2542.3
Mar 2543.04
Feb 2539.35
Feb 2543.49
Feb 2544.03
Feb 2547.27
Jan 2540.52
Jan 2541.06
Jan 2541.33
Jan 2547.54
Jan 2551.86
Dec 2447.27
Dec 2449.97
Dec 2455.91
Dec 2466.99
Nov 2487.52
Nov 2466.72
Nov 2455.64
Nov 2427.13
Nov 2427.67
Oct 2435.99
Oct 2437.26
Price to Book
051015med 7Dec 24Apr 25Jul 25Oct 25Feb 26May 26Sep 26
TSHA Price to Book by year
PeriodPrice to Book
Sep 264.78
Sep 265.34
Aug 265.5
Aug 265.8
Aug 265.67
Aug 2611.35
Jul 2610.14
Jul 269.55
Jul 2610.31
Jul 2610.97
Jul 2611.3
Jun 2610.97
Jun 2611.11
Jun 269.88
Jun 269.51
May 2610.15
May 269.5
May 2610.31
May 2611.78
May 268.2
Apr 268.29
Apr 268.32
Apr 265.81
Apr 265.66
Mar 265.27
Mar 265.7
Mar 267.24
Mar 267.37
Feb 267.31
Feb 267.58
Feb 267.34
Feb 267.44
Jan 267.28
Jan 267.52
Jan 267.36
Jan 268.03
Jan 268.47
Dec 259.41
Dec 258.86
Dec 259.34
Dec 258.15
Nov 257.65
Nov 256.76
Nov 256.66
Nov 256.18
Oct 255.94
Oct 255.69
Oct 255.65
Oct 255.85
Oct 255.7
Sep 253.89
Sep 253.39
Sep 253.68
Sep 254.03
Aug 253.5
Aug 253.59
Aug 253.52
Aug 2513.3
Aug 2512.86
Jul 2512.96
Jul 2512.57
Jul 2512.91
Jul 2511.98
Jun 2511.64
Jun 2512.03
Jun 2512.42
Jun 2513.89
May 2513.26
May 2513.45
May 2513.21
May 256.1
May 257.39
Apr 255.04
Apr 253.55
Apr 253.58
Apr 253.5
Mar 255.53
Mar 254.7
Mar 254.93
Mar 255.01
Feb 254.58
Feb 254.86
Feb 254.92
Feb 255.28
Jan 254.52
Jan 254.58
Jan 254.61
Jan 255.31
Jan 255.79
Dec 245.28
Dec 245.58
Dec 246.24
Dec 247.48
Nov 249.77
Nov 247.45
Nov 246.21
Nov 243.21
Nov 243.27
Oct 244.26
Oct 244.41
Taysha Gene Therapies, Inc.
TSHA
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News: TSHA

Taysha Gene Therapies: A Bull Case That Does Not Require The Fastest Approval

seekingalpha.com · 11 Sep 2026

Taysha Gene Therapies: A Bull Case That Does Not Require The Fastest Approval

Taysha Gene Therapies offers a speculative opportunity, hinging on durable clinical gains, safety, and disciplined execution for TSHA-102 in Rett syndrome. TSHA's $455.4M cash runway extends into H2 2028, supporting pivotal data collection and manufacturing scale-up without immediate dependence on accelerated regulatory filing. TSHA-102's early data show deepening, durable functional gains in Rett patients, but pivotal efficacy, safety, and manufacturing qualification remain key investment inflection points.

These 3 Risky Stocks Could Be Sitting on 100% Upside

marketbeat.com · 7 Sep 2026

These 3 Risky Stocks Could Be Sitting on 100% Upside

With industrials, energy, and tech stocks undergirding an S&P 500 that is hovering near all-time highs, investors looking for high-upside companies may be resigned to more speculative plays. While it's true that some long-established firms have posted surprising rallies in recent trading sessions, a combination of consumer reticence and stretched valuations means that many go-to investments may not see much near-term growth.

Taysha Gene Therapies Announces Inducement Grant Under Nasdaq Listing Rule 5635(c)(4)

globenewswire.com · 4 Sep 2026

Taysha Gene Therapies Announces Inducement Grant Under Nasdaq Listing Rule 5635(c)(4)

DALLAS, Sept. 04, 2026 (GLOBE NEWSWIRE) -- Taysha Gene Therapies, Inc. (Nasdaq: TSHA) (Taysha or the Company), a clinical-stage biotechnology company focused on advancing adeno-associated virus (AAV)-based gene therapies for severe monogenic diseases of the central nervous system (CNS), today announced that, on September 1, 2026, the Compensation Committee of Taysha's Board of Directors granted five new employees restricted stock units (RSUs) representing 314,000 shares of the Company's common stock and an option to purchase 92,400 shares of the Company's common stock in connection with their employment. The RSUs and stock option were granted under the Taysha Gene Therapies, Inc. 2023 Inducement Plan as an inducement material to the individuals entering employment with Taysha in accordance with Nasdaq Listing Rule 5635(c)(4).

Bank of America Corp DE Has $7.50 Million Stake in Taysha Gene Therapies, Inc. $TSHA

defenseworld.net · 26 Aug 2026

Bank of America Corp DE Has $7.50 Million Stake in Taysha Gene Therapies, Inc. $TSHA

Bank of America Corp DE raised its stake in Taysha Gene Therapies, Inc. (NASDAQ: TSHA) by 45.5% in the first quarter, according to its most recent Form 13F filing with the Securities and Exchange Commission. The fund owned 1,677,046 shares of the company's stock after acquiring an additional 524,366 shares during the quarter.

Taysha Gene Therapies, Inc. (TSHA) Q2 2026 Earnings Call Transcript

seekingalpha.com · 11 Aug 2026

Taysha Gene Therapies, Inc. (TSHA) Q2 2026 Earnings Call Transcript

Taysha Gene Therapies, Inc. (TSHA) Q2 2026 Earnings Call Transcript

Taysha Gene Therapies Q2 Earnings Call Highlights

marketbeat.com · 11 Aug 2026

Taysha Gene Therapies Q2 Earnings Call Highlights

Taysha Gene Therapies NASDAQ: TSHA said it completed dosing in its REVEAL pivotal trial and ASPIRE trial for TSHA-102, its gene therapy candidate for Rett syndrome, while preparing for a potential biologics license application submission.

Taysha Gene Therapies Reports Second Quarter 2026 Financial Results and Provides Corporate Update

globenewswire.com · 11 Aug 2026

Taysha Gene Therapies Reports Second Quarter 2026 Financial Results and Provides Corporate Update

Completed dosing in the REVEAL pivotal (N=17) and ASPIRE (N=4) trials evaluating TSHA-102 for Rett syndrome; expect to report topline data from 6 ‑ month interim analysis and FDA feedback on the BLA submission pathway in 1H 2027

Taysha Gene Therapies Announces Inducement Grant Under Nasdaq Listing Rule 5635(c)(4)

globenewswire.com · 7 Aug 2026

Taysha Gene Therapies Announces Inducement Grant Under Nasdaq Listing Rule 5635(c)(4)

DALLAS, Aug. 07, 2026 (GLOBE NEWSWIRE) -- Taysha Gene Therapies, Inc. (Nasdaq: TSHA) (Taysha or the Company), a clinical-stage biotechnology company focused on advancing adeno-associated virus (AAV)-based gene therapies for severe monogenic diseases of the central nervous system (CNS), today announced that, on August 3, 2026, the Compensation Committee of Taysha's Board of Directors granted one new employee restricted stock units (RSUs) representing 144,000 shares of the Company's common stock and an option to purchase 92,400 shares of the Company's common stock in connection with their employment. The RSUs and stock option were granted under the Taysha Gene Therapies, Inc. 2023 Inducement Plan as an inducement material to the individuals entering employment with Taysha in accordance with Nasdaq Listing Rule 5635(c)(4).

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