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Stoke Therapeutics, Inc.

$29.03 -$1.87 (-6.05%)
NASDAQ · 11 Sep 2026 20:00 UTC
Previous Close
$29.34
Day Range
$29.03$30.16
Year Range
$20.32$40.22
Market Cap
1.87B
AVG Volume
782.18K
Trailing/Forward PE
-8.64/-
PEG ratio
3.92
Dividend Yield
-
Next Earnings Date
2026-11-03
Primary Exchange
NASDAQUS
Revenue (USD)
050M100M150M200M20182019202020212022202320242025
STOK Revenue (USD) by year
PeriodRevenue (USD)
2025184.42M
202436.55M
20238.78M
202212.4M
20210
20200
20190
20180
Net Income (USD)
-150M-100M-50M020182019202020212022202320242025
STOK Net Income (USD) by year
PeriodNet Income (USD)
2025-6.88M
2024-88.98M
2023-104.7M
2022-101.07M
2021-85.81M
2020-52.24M
2019-32.33M
2018-12.52M
Operating Income (USD)
-150M-100M-50M020182019202020212022202320242025
STOK Operating Income (USD) by year
PeriodOperating Income (USD)
2025-20.59M
2024-101.37M
2023-114.77M
2022-104.36M
2021-86.06M
2020-53.04M
2019-35.68M
2018-12.78M
EBITDA (USD)
-150M-100M-50M020182019202020212022202320242025
STOK EBITDA (USD) by year
PeriodEBITDA (USD)
2025-3.91M
2024-86.8M
2023-100.56M
2022-97.53M
2021-84.86M
2020-52.16M
2019-35.23M
2018-12.57M
Cash Flows (USD)
-100M-50M050M20182019202020212022202320242025
STOK Cash Flows (USD) by year
PeriodCash Flows (USD)
202544.91M
2024-87.05M
2023-82.68M
2022-35.83M
2021-68.11M
2020-43.27M
2019-32.69M
2018-11.9M
EPS (USD)
-3-2-1020182019202020212022202320242025
STOK EPS (USD) by year
PeriodEPS (USD)
2025-0.14
2024-1.68
2023-2.27
2022-2.41
2021-2.33
2020-1.56
2019-1.1
2018-0.53
Expenses (USD)
0100M200M300MR&DSG&ACapex20182019202020212022202320242025
STOK Expenses (USD) by year
PeriodExpenses (USD)
2025203.64M
2024135.91M
2023120.44M
2022117.19M
202187.26M
202054.09M
201937.31M
201813.72M
Cash & Debt (USD)
0100M200M300M20182019202020212022202320242025
STOK Cash & Debt (USD) by year
PeriodCash & Debt (USD)
2025284.67M
2024216.9M
2023201.39M
2022229.59M
2021219.81M
2020287.31M
2019222.47M
2018105.4M
Debt ratios
00.511.520212022202320242025
STOK Debt ratios by year
PeriodDebt ratios
20250.98
20240.57
20230.59
20220.84
20211.16
Margins
0%25%50%75%100%2022202320242025
STOK Margins by year
PeriodMargins
202598.89%
202493.92%
202346.15%
202271.5%
Return on Capital
-80%-60%-40%-20%0%20182019202020212022202320242025
STOK Return on Capital by year
PeriodReturn on Capital
2025-1.95%
2024-38.85%
2023-65.62%
2022-54.68%
2021-39.4%
2020-18.26%
2019-14.4%
2018-11.92%
Shares Outstanding
020M40M60M20182019202020212022202320242025
STOK Shares Outstanding by year
PeriodShares Outstanding
202558.39M
202457.03M
202344.96M
202239.43M
202136.84M
202035.07M
201925.34M
201823.51M
Book Value Per Share (USD)
02.557.51020182019202020212022202320242025
STOK Book Value Per Share (USD) by year
PeriodBook Value Per Share (USD)
20256.04
20244.02
20233.55
20224.69
20215.91
20208.16
20198.86
20184.47
Total Assets (USD)
0200M400M600M20182019202020212022202320242025
STOK Total Assets (USD) by year
PeriodTotal Assets (USD)
2025418.43M
2024271.56M
2023228.34M
2022256.07M
2021238.87M
2020297.93M
2019228.75M
2018107.54M
Employee Count
0501001502002019202020212022202320242025
STOK Employee Count by year
PeriodEmployee Count
2025170
2024128
2023110
2022117
2021102
202079
201956
PE Ratio
0204060med 33.21May 25Jul 25Aug 25Oct 25Dec 25Jan 26Mar 26
STOK PE Ratio by year
PeriodPE Ratio
Mar 2647.95
Mar 2651.26
Feb 2652.61
Feb 2649.54
Feb 2646.1
Feb 2646.81
Jan 2643.84
Jan 2642.56
Jan 2641.47
Jan 2647.46
Jan 2644.64
Dec 2546.12
Dec 2546.18
Dec 2546.8
Dec 2544.6
Nov 2544.66
Nov 2542.39
Nov 2538.3
Nov 2533.03
Oct 2533.4
Oct 2535.89
Oct 2537.28
Oct 2533.57
Oct 2528.42
Sep 2526.84
Sep 2525.46
Sep 2526.08
Sep 2522.99
Aug 2521.97
Aug 2521.75
Aug 2520.25
Aug 2515.08
Aug 2514.86
Jul 2515.08
Jul 2515.22
Jul 2513.65
Jul 2513.21
Jun 2513.39
Jun 2513.33
Jun 2513.27
Jun 2512.82
May 2510.98
May 2510.77
May 2511.23
Free Cash Flow Yield
-30%-20%-10%0%10%20%med 2.15%Dec 24Apr 25Jul 25Oct 25Feb 26May 26Sep 26
STOK Free Cash Flow Yield by year
PeriodFree Cash Flow Yield
Sep 26-9.43%
Sep 26-9.18%
Aug 26-8.66%
Aug 26-8.48%
Aug 26-8.75%
Aug 26-8.37%
Jul 26-8.12%
Jul 26-7.99%
Jul 26-8.06%
Jul 26-7.46%
Jul 26-7.16%
Jun 26-7.32%
Jun 26-7.55%
Jun 26-7.85%
Jun 26-7.8%
May 26-7.58%
May 26-7.98%
May 26-7.79%
May 26-7.12%
May 262.33%
Apr 262.26%
Apr 262.06%
Apr 262.24%
Apr 262.35%
Mar 262.34%
Mar 262.3%
Mar 262.69%
Mar 262.52%
Feb 262.45%
Feb 262.61%
Feb 262.8%
Feb 262.76%
Jan 262.94%
Jan 263.03%
Jan 263.11%
Jan 262.72%
Jan 262.89%
Dec 252.8%
Dec 252.8%
Dec 252.76%
Dec 252.89%
Nov 252.89%
Nov 253.05%
Nov 253.37%
Nov 253.91%
Oct 253.49%
Oct 253.25%
Oct 253.13%
Oct 253.47%
Oct 254.1%
Sep 254.34%
Sep 254.58%
Sep 254.47%
Sep 255.07%
Aug 255.3%
Aug 255.36%
Aug 255.75%
Aug 259.13%
Aug 259.26%
Jul 259.13%
Jul 259.05%
Jul 2510.08%
Jul 2510.42%
Jun 2510.28%
Jun 2510.33%
Jun 2510.37%
Jun 2510.74%
May 2512.54%
May 2512.78%
May 2512.25%
May 25-16.31%
May 25-15.85%
Apr 25-15.64%
Apr 25-19.85%
Apr 25-21.74%
Apr 25-25.7%
Mar 25-21.17%
Mar 25-18.73%
Mar 25-17.48%
Mar 25-18.77%
Feb 25-19.15%
Feb 25-18.05%
Feb 25-14.08%
Feb 25-13.24%
Jan 25-13.09%
Jan 25-14.16%
Jan 25-16.06%
Jan 25-16.7%
Jan 25-13.08%
Dec 24-13.59%
Dec 24-12.87%
Dec 24-12.47%
Dec 24-11.33%
Nov 24-12.41%
Nov 24-13.15%
Nov 24-12.5%
Nov 24-10.83%
Nov 24-11.24%
Oct 24-12.14%
Oct 24-11.12%
Price to Sales
020406080med 10.82Dec 24Apr 25Jul 25Oct 25Feb 26May 26Sep 26
STOK Price to Sales by year
PeriodPrice to Sales
Sep 2669.47
Sep 2671.34
Aug 2675.67
Aug 2677.27
Aug 2674.83
Aug 2678.27
Jul 2656.73
Jul 2657.6
Jul 2657.11
Jul 2661.69
Jul 2664.28
Jun 2662.91
Jun 2660.94
Jun 2658.62
Jun 2658.99
May 2660.76
May 2657.68
May 2659.13
May 2664.66
May 2610.47
Apr 2610.77
Apr 2611.8
Apr 2610.87
Apr 2610.37
Mar 2610.4
Mar 2610.61
Mar 269.46
Mar 2610.11
Feb 2610.38
Feb 269.77
Feb 269.1
Feb 269.24
Jan 268.65
Jan 268.4
Jan 268.18
Jan 269.36
Jan 268.81
Dec 259.1
Dec 259.11
Dec 259.23
Dec 258.8
Nov 258.81
Nov 258.36
Nov 257.56
Nov 256.52
Oct 258.77
Oct 259.42
Oct 259.79
Oct 258.81
Oct 257.46
Sep 257.05
Sep 256.69
Sep 256.85
Sep 256.04
Aug 255.77
Aug 255.71
Aug 255.32
Aug 253.97
Aug 253.91
Jul 253.97
Jul 254.01
Jul 253.59
Jul 253.48
Jun 253.52
Jun 253.51
Jun 253.49
Jun 253.38
May 252.89
May 252.84
May 252.96
May 2514.6
May 2515.02
Apr 2515.23
Apr 2512
Apr 2510.95
Apr 259.27
Mar 2511.25
Mar 2512.71
Mar 2528.94
Mar 2526.95
Feb 2526.42
Feb 2528.03
Feb 2535.94
Feb 2538.19
Jan 2538.63
Jan 2535.74
Jan 2531.5
Jan 2530.29
Jan 2538.66
Dec 2437.22
Dec 2439.3
Dec 2440.58
Dec 2444.65
Nov 2440.75
Nov 2438.46
Nov 2440.48
Nov 2446.71
Nov 2447.31
Oct 2443.82
Oct 2447.83
EV/EBITDA
0204060med 26.24May 25Jul 25Aug 25Oct 25Dec 25Jan 26Mar 26
STOK EV/EBITDA by year
PeriodEV/EBITDA
Mar 2639.53
Mar 2642.65
Feb 2643.91
Feb 2641.02
Feb 2637.78
Feb 2638.45
Jan 2635.64
Jan 2634.44
Jan 2633.41
Jan 2639.06
Jan 2636.4
Dec 2537.79
Dec 2537.85
Dec 2538.44
Dec 2536.36
Nov 2536.42
Nov 2534.28
Nov 2530.42
Nov 2525.45
Oct 2527.04
Oct 2529.39
Oct 2530.69
Oct 2527.2
Oct 2522.35
Sep 2520.87
Sep 2519.57
Sep 2520.15
Sep 2517.24
Aug 2516.28
Aug 2516.07
Aug 2514.66
Aug 257.51
Aug 257.31
Jul 257.51
Jul 257.64
Jul 256.18
Jul 255.77
Jun 255.93
Jun 255.87
Jun 255.82
Jun 255.4
May 253.67
May 253.48
May 253.91
Price/Operating Cashflow
01020304050med 30.58May 25Jul 25Sep 25Nov 25Jan 26Mar 26May 26
STOK Price/Operating Cashflow by year
PeriodPrice/Operating Cashflow
May 2642.37
Apr 2643.59
Apr 2647.74
Apr 2643.97
Apr 2641.94
Mar 2642.08
Mar 2642.92
Mar 2636.81
Mar 2639.35
Feb 2640.38
Feb 2638.03
Feb 2635.39
Feb 2635.93
Jan 2633.65
Jan 2632.67
Jan 2631.83
Jan 2636.43
Jan 2634.27
Dec 2535.4
Dec 2535.45
Dec 2535.92
Dec 2534.24
Nov 2534.28
Nov 2532.54
Nov 2529.4
Nov 2525.35
Oct 2528.46
Oct 2530.58
Oct 2531.76
Oct 2528.6
Oct 2524.21
Sep 2522.87
Sep 2521.69
Sep 2522.22
Sep 2519.59
Aug 2518.72
Aug 2518.53
Aug 2517.25
Aug 2510.9
Aug 2510.74
Jul 2510.9
Jul 2511
Jul 259.87
Jul 259.55
Jun 259.68
Jun 259.64
Jun 259.59
Jun 259.27
May 257.94
May 257.79
May 258.12
Price to Book
02468med 4.28Dec 24Apr 25Jul 25Oct 25Feb 26May 26Sep 26
STOK Price to Book by year
PeriodPrice to Book
Sep 265.55
Sep 265.7
Aug 266.04
Aug 266.17
Aug 265.97
Aug 266.25
Jul 264.61
Jul 264.68
Jul 264.64
Jul 265.01
Jul 265.22
Jun 265.11
Jun 264.95
Jun 264.76
Jun 264.79
May 264.94
May 264.69
May 264.8
May 265.25
May 265.48
Apr 265.64
Apr 266.17
Apr 265.69
Apr 265.42
Mar 265.44
Mar 265.55
Mar 266.31
Mar 266.75
Feb 266.93
Feb 266.52
Feb 266.07
Feb 266.16
Jan 265.77
Jan 265.6
Jan 265.46
Jan 266.25
Jan 265.88
Dec 256.07
Dec 256.08
Dec 256.16
Dec 255.87
Nov 255.88
Nov 255.58
Nov 255.04
Nov 254.35
Oct 255.23
Oct 255.62
Oct 255.84
Oct 255.26
Oct 254.45
Sep 254.21
Sep 253.99
Sep 254.09
Sep 253.6
Aug 253.44
Aug 253.41
Aug 253.17
Aug 252.17
Aug 252.13
Jul 252.17
Jul 252.19
Jul 251.96
Jul 251.9
Jun 251.92
Jun 251.91
Jun 251.91
Jun 251.84
May 251.58
May 251.55
May 251.61
May 252.33
May 252.4
Apr 252.43
Apr 251.91
Apr 251.75
Apr 251.48
Mar 251.8
Mar 252.03
Mar 252.09
Mar 251.94
Feb 251.91
Feb 252.02
Feb 252.59
Feb 252.75
Jan 252.79
Jan 252.58
Jan 252.27
Jan 252.18
Jan 252.79
Dec 242.68
Dec 242.84
Dec 242.93
Dec 243.22
Nov 242.94
Nov 242.77
Nov 242.92
Nov 243.37
Nov 242.95
Oct 242.74
Oct 242.99
Stoke Therapeutics, Inc.
STOK
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News: STOK

Stoke Therapeutics and Biogen Present Long-Term Clinical Data that Support the Disease-Modifying Potential of Zorevunersen, an Investigational Medicine for the Treatment of Dravet Syndrome, at the 16t

gurufocus.com · 3 Sep 2026

Stoke Therapeutics and Biogen Present Long-Term Clinical Data that Support the Disease-Modifying Potential of Zorevunersen, an Investigational Medicine for the Treatment of Dravet Syndrome, at the 16t

[url="]Stoke Therapeutics, Inc.[/url] (Nasdaq: STOK), a biotechnology company dedicated to restoring protein expression by harnessing the body's potential with

Stoke Therapeutics and Biogen Present Long-Term Clinical Data that Support the Disease-Modifying Potential of Zorevunersen, an Investigational Medicine for the Treatment of Dravet Syndrome, at the 16th European Epilepsy Congress (EEC)

businesswire.com · 3 Sep 2026

Stoke Therapeutics and Biogen Present Long-Term Clinical Data that Support the Disease-Modifying Potential of Zorevunersen, an Investigational Medicine for the Treatment of Dravet Syndrome, at the 16th European Epilepsy Congress (EEC)

BEDFORD, Mass. & CAMBRIDGE, Mass.--(BUSINESS WIRE)--Stoke Therapeutics, Inc. (Nasdaq: STOK), a biotechnology company dedicated to restoring protein expression by harnessing the body's potential with RNA medicine, and Biogen Inc. (Nasdaq: BIIB) today announced presentations of data at the 16th European Epilepsy Congress (EEC), taking place September 5-9 in Athens, Greece. These data support the potential of zorevunersen as a first-in-class disease-modifying treatment for Dravet syndrome. Dravet.

Stoke Therapeutics to Present at the Cantor Global Healthcare Conference

businesswire.com · 2 Sep 2026

Stoke Therapeutics to Present at the Cantor Global Healthcare Conference

BEDFORD, Mass.--(BUSINESS WIRE)--Stoke Therapeutics, Inc. (Nasdaq: STOK) is a biotechnology company dedicated to restoring protein expression by harnessing the body's potential with RNA medicine and has a lead investigational medicine, zorevunersen, in development as a first-in-class potential disease-modifying treatment for Dravet syndrome. Today, the Company announced that Chief Executive Officer Ian F. Smith and Chief Patient Officer Jason Hoitt will present at the Cantor Global Healthcare C.

Bank of America Corp DE Buys 336,931 Shares of Stoke Therapeutics, Inc. $STOK

defenseworld.net · 20 Aug 2026

Bank of America Corp DE Buys 336,931 Shares of Stoke Therapeutics, Inc. $STOK

Bank of America Corp DE lifted its stake in shares of Stoke Therapeutics, Inc. (NASDAQ: STOK) by 163.4% in the first quarter, according to the company in its most recent filing with the SEC. The fund owned 543,095 shares of the company's stock after buying an additional 336,931 shares during the quarter. Bank

Stoke Therapeutics Announces Inducement Grants Under Nasdaq Listing Rule 5635(C)(4)

businesswire.com · 18 Aug 2026

Stoke Therapeutics Announces Inducement Grants Under Nasdaq Listing Rule 5635(C)(4)

BEDFORD, Mass.--(BUSINESS WIRE)--Stoke Therapeutics, Inc. (Nasdaq: STOK) is a biotechnology company dedicated to restoring protein expression by harnessing the body's potential with RNA medicine and has a lead investigational medicine, zorevunersen, in development as a first-in-class potential disease-modifying treatment for Dravet syndrome. The Company today announced that, effective on August 17, 2026, it granted stock options to purchase an aggregate of 70,950 shares of common stock to seven.

Stoke Therapeutics' Dravet Trial Tops Enrollment Target With Zero Dropouts

marketbeat.com · 17 Aug 2026

Stoke Therapeutics' Dravet Trial Tops Enrollment Target With Zero Dropouts

Stoke Therapeutics NASDAQ: STOK said its Phase III EMPEROR study of zorevunersen for Dravet syndrome has enrolled 162 patients, exceeding its target enrollment of 150, with no patient discontinuations reported to date.

Dimensional Fund Advisors LP Buys 162,797 Shares of Stoke Therapeutics, Inc. $STOK

defenseworld.net · 5 Aug 2026

Dimensional Fund Advisors LP Buys 162,797 Shares of Stoke Therapeutics, Inc. $STOK

Dimensional Fund Advisors LP grew its position in Stoke Therapeutics, Inc. (NASDAQ: STOK) by 19.7% in the first quarter, according to its most recent filing with the SEC. The fund owned 989,936 shares of the company's stock after acquiring an additional 162,797 shares during the period. Dimensional Fund Advisors LP owned 1.59% of

Stoke Therapeutics Q2 Earnings Call Highlights

defenseworld.net · 5 Aug 2026

Stoke Therapeutics Q2 Earnings Call Highlights

Stoke Therapeutics (NASDAQ: STOK) said its Phase III EMPEROR study of zorevunersen in patients with Dravet syndrome remains on track for a data readout in the third quarter of 2027, following completion of enrollment ahead of the company's planned rolling new drug application submission. The global, double-blind, sham-controlled study enrolled 162 patients in 10 months, exceeding

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