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Summit Therapeutics Inc.

$17.55 +$0.03 (+0.17%)
NASDAQ · 11 Sep 2026 20:00 UTC
Previous Close
$17
Day Range
$17.14$17.7
Year Range
$12.07$29.23
Market Cap
14B
AVG Volume
5.24M
Trailing/Forward PE
-15.67/-
PEG ratio
6.54
Dividend Yield
-
Next Earnings Date
2026-10-19
Primary Exchange
NASDAQUS
Revenue (USD)
020M40M60M2016201720182019202020212022202320242025
SMMT Revenue (USD) by year
PeriodRevenue (USD)
20250
20240
20230
2022580.38K
20211.34M
2020673.35K
20195.2M
201857.09M
201714.17M
20162.38M
Net Income (USD)
-1B-750M-500M-250M0250M2016201720182019202020212022202320242025
SMMT Net Income (USD) by year
PeriodNet Income (USD)
2025-911.82M
2024-173.18M
2023-497.35M
2022-65.12M
2021-64.92M
2020-40.92M
2019-24.64M
20183.75M
2017-20.19M
2016-21.37M
Operating Income (USD)
-1B-750M-500M-250M0250M2016201720182019202020212022202320242025
SMMT Operating Income (USD) by year
PeriodOperating Income (USD)
2025-924.97M
2024-176.83M
2023-493.05M
2022-59.26M
2021-63.15M
2020-51.71M
2019-26.29M
201818.8M
2017-25.77M
2016-24.85M
EBITDA (USD)
-1B-750M-500M-250M02016201720182019202020212022202320242025
SMMT EBITDA (USD) by year
PeriodEBITDA (USD)
2025-913.62M
2024-155.05M
2023-62.58M
2022-57.51M
2021-62.14M
2020-39.62M
2019-22.85M
2018-4.86M
2017-26.62M
2016-24.79M
Cash Flows (USD)
-300M-200M-100M0100M2016201720182019202020212022202320242025
SMMT Cash Flows (USD) by year
PeriodCash Flows (USD)
2025-241.7M
2024-112.2M
2023-61.48M
2022-34.3M
2021-53.31M
2020-38.95M
2019-22.49M
2018-35M
2017-21.26M
201615.07M
EPS (USD)
-1.5-1-0.500.52016201720182019202020212022202320242025
SMMT EPS (USD) by year
PeriodEPS (USD)
2025-1.23
2024-0.25
2023-1.24
2022-0.5
2021-0.71
2020-0.58
2019-0.61
20180.02
2017-0.3
2016-0.35
Expenses (USD)
0250M500M750M1BR&DSG&ACapex2016201720182019202020212022202320242025
SMMT Expenses (USD) by year
PeriodExpenses (USD)
2025925.47M
2024176.9M
2023493.96M
202265.31M
202180.06M
202056.96M
201943.66M
201855.11M
201741.65M
201627.34M
Cash & Debt (USD)
-200M0200M400M600MCashLong Term DebtShort Term Debt2016201720182019202020212022202320242025
SMMT Cash & Debt (USD) by year
PeriodCash & Debt (USD)
2025529.49M
2024329.5M
2023147.38M
2022284.18M
202153.22M
202048.78M
201937.54M
201835.23M
201728.45M
201635.08M
Debt ratios
-1-0.500.5120182019202020212022202320242025
SMMT Debt ratios by year
PeriodDebt ratios
20250.43
20240.96
20230.29
2022-0.76
20210.4
20200.52
20190.49
20180.46
Margins
0%25%50%75%100%20152016201720182019202020212022
SMMT Margins by year
PeriodMargins
2022100%
2021100%
2020100%
2019100%
201899.68%
2017100%
2016100%
2015100%
Return on Capital
-1000%-500%0%500%2016201720182019202020212022202320242025
SMMT Return on Capital by year
PeriodReturn on Capital
2025-186.47%
2024-55.75%
2023-808.94%
2022-63.07%
2021-105.16%
2020-70.11%
2019-40.32%
20186.71%
2017452.53%
2016489.45%
Shares Outstanding
0200M400M600M800M2016201720182019202020212022202320242025
SMMT Shares Outstanding by year
PeriodShares Outstanding
2025766.4M
2024683.17M
2023700.61M
2022267.93M
202196.72M
202073.57M
201935.76M
201882.14M
201770.98M
201661.82M
Book Value Per Share (USD)
-0.500.511.522016201720182019202020212022202320242025
SMMT Book Value Per Share (USD) by year
PeriodBook Value Per Share (USD)
20250.64
20240.45
20230.09
20220.39
20210.64
20200.79
20191.71
20180.68
2017-0.06
2016-0.07
Total Assets (USD)
0200M400M600M2016201720182019202020212022202320242025
SMMT Total Assets (USD) by year
PeriodTotal Assets (USD)
2025557.5M
2024348.05M
2023160.6M
2022541.43M
202184.04M
202075.29M
201975.46M
201879.53M
201778.1M
201646.98M
Employee Count
01002003002017201820192019202020212022202320242025
SMMT Employee Count by year
PeriodEmployee Count
2025265
2024159
2023105
202276
2021105
202079
201970
201961
201876
201740
Free Cash Flow Yield
-5%-4%-3%-2%-1%0%med -1.04%Dec 24Apr 25Jul 25Oct 25Feb 26May 26Sep 26
SMMT Free Cash Flow Yield by year
PeriodFree Cash Flow Yield
Sep 26-2.98%
Sep 26-2.97%
Aug 26-3.81%
Aug 26-3.97%
Aug 26-3.91%
Aug 26-3.74%
Jul 26-4.01%
Jul 26-3.83%
Jul 26-2.68%
Jul 26-2.43%
Jul 26-2.4%
Jun 26-2.64%
Jun 26-2.69%
Jun 26-2.64%
Jun 26-2.51%
May 26-2.11%
May 26-2.23%
May 26-2.19%
May 26-2.05%
May 26-2.3%
Apr 26-1.43%
Apr 26-1.25%
Apr 26-1.6%
Apr 26-1.63%
Mar 26-1.9%
Mar 26-2.03%
Mar 26-1.96%
Mar 26-2.09%
Feb 26-1.9%
Feb 26-1.73%
Feb 26-1.84%
Feb 26-1.84%
Jan 26-1.9%
Jan 26-1.67%
Jan 26-1.62%
Jan 26-1.4%
Jan 26-1.57%
Dec 25-1.52%
Dec 25-1.55%
Dec 25-1.57%
Dec 25-1.5%
Nov 25-1.19%
Nov 25-1.32%
Nov 25-1.19%
Nov 25-1.18%
Oct 25-1.13%
Oct 25-1.11%
Oct 25-1.02%
Oct 25-1%
Oct 25-1%
Sep 25-1.02%
Sep 25-1.13%
Sep 25-1.13%
Sep 25-0.82%
Aug 25-0.9%
Aug 25-0.82%
Aug 25-0.8%
Aug 25-0.68%
Aug 25-0.72%
Jul 25-0.68%
Jul 25-0.74%
Jul 25-0.78%
Jul 25-0.79%
Jun 25-0.94%
Jun 25-0.95%
Jun 25-0.98%
Jun 25-0.94%
May 25-1.07%
May 25-0.75%
May 25-0.81%
May 25-0.81%
May 25-0.7%
Apr 25-0.7%
Apr 25-0.67%
Apr 25-0.71%
Apr 25-0.95%
Mar 25-0.81%
Mar 25-0.83%
Mar 25-0.79%
Mar 25-0.92%
Feb 25-0.79%
Feb 25-0.57%
Feb 25-0.59%
Feb 25-0.63%
Jan 25-0.59%
Jan 25-0.53%
Jan 25-0.66%
Jan 25-0.71%
Jan 25-0.69%
Dec 24-0.69%
Dec 24-0.71%
Dec 24-0.71%
Dec 24-0.68%
Nov 24-0.68%
Nov 24-0.66%
Nov 24-0.69%
Nov 24-0.59%
Nov 24-0.66%
Oct 24-0.55%
Oct 24-0.55%
Price to Sales
02000400060008000med 264.7Feb 22May 22Sep 22Dec 22Apr 23Jul 23Nov 23
SMMT Price to Sales by year
PeriodPrice to Sales
Nov 237118.27
Oct 236409.98
Oct 236551.64
Oct 235949.6
Oct 236232.91
Sep 236622.47
Sep 236622.47
Sep 236622.47
Sep 235453.8
Sep 235772.53
Aug 236303.74
Aug 236232.91
Aug 236091.26
Aug 231880.82
Jul 232055.33
Jul 231938.99
Jul 232074.72
Jul 232123.2
Jun 232433.44
Jun 232569.17
Jun 232016.55
Jun 231696.62
Jun 231754.79
May 231599.67
May 231628.76
May 231667.53
May 231001.79
Apr 23609.38
Apr 23724.79
Apr 23724.79
Apr 23706.33
Mar 23807.89
Mar 23812.51
Mar 23770.96
Mar 23687.86
Mar 23298.72
Feb 23413.17
Feb 23461.67
Feb 23451.97
Feb 23609.09
Jan 23626.55
Jan 23851.56
Jan 23931.09
Jan 23814.7
Dec 22824.4
Dec 22711.9
Dec 22700.26
Dec 22760.39
Dec 22151.3
Nov 22179.04
Nov 22189.9
Nov 22199.8
Nov 2266.64
Oct 2271.16
Oct 2272.46
Oct 2275.05
Oct 2265.99
Sep 2276.99
Sep 2278.93
Sep 2283.46
Sep 2283.46
Sep 2282.81
Aug 2278.93
Aug 2271.16
Aug 2268.58
Aug 2262.93
Jul 2271.33
Jul 2275.57
Jul 2277.69
Jul 2272.04
Jul 2267.1
Jun 2280.52
Jun 2269.22
Jun 2267.66
Jun 2279.81
May 2278.4
May 2272.75
May 2279.81
May 2280.99
Apr 22114.98
Apr 22143.91
Apr 22156.93
Apr 22159.82
Apr 22171.39
Mar 22205.38
Mar 22227.07
Mar 22212.41
Mar 22210.12
Feb 22188.8
Feb 22154.55
Feb 22161.4
Feb 22156.83
Jan 22157.59
Jan 22156.83
Jan 22181.95
Jan 22203.27
Dec 21204.79
Dec 21230.68
Dec 21379.13
Dec 21377.61
Price to Book
0255075100125med 46.14Dec 24Apr 25Jul 25Oct 25Feb 26May 26Sep 26
SMMT Price to Book by year
PeriodPrice to Book
Sep 2621.68
Sep 2621.75
Aug 2616.96
Aug 2616.26
Aug 2616.49
Aug 2617.24
Jul 2616.08
Jul 2616.87
Jul 2625.87
Jul 2628.56
Jul 2628.88
Jun 2626.24
Jun 2625.75
Jun 2626.24
Jun 2627.66
May 2632.85
May 2631.13
May 2631.6
May 2633.86
May 2630.17
Apr 2634.61
Apr 2639.42
Apr 2630.83
Apr 2630.38
Mar 2625.99
Mar 2624.31
Mar 2625.27
Mar 2623.68
Feb 2626
Feb 2682.91
Feb 2677.82
Feb 2677.97
Jan 2675.32
Jan 2685.78
Jan 2688.64
Jan 26102.37
Jan 2691.13
Dec 2594.36
Dec 2592.69
Dec 2591.39
Dec 2595.24
Nov 2569.79
Nov 2563.16
Nov 2570.34
Nov 2570.92
Oct 2573.77
Oct 2575.21
Oct 2581.88
Oct 2583.29
Oct 2583.6
Sep 2581.73
Sep 2573.69
Sep 2573.89
Sep 25101.35
Aug 2592.45
Aug 25102.21
Aug 25104.12
Aug 2575.12
Aug 2570.95
Jul 2575.15
Jul 2568.67
Jul 2565.53
Jul 2564.35
Jun 2553.99
Jun 2553.89
Jun 2551.84
Jun 2553.97
May 2547.76
May 2567.75
May 2562.56
May 2562.8
May 2573.13
Apr 2551.62
Apr 2554.12
Apr 2551.11
Apr 2538.18
Mar 2544.69
Mar 2543.43
Mar 2545.72
Mar 2539.1
Feb 2545.5
Feb 2546.55
Feb 2544.98
Feb 2542.32
Jan 2545.25
Jan 2550.01
Jan 2540.05
Jan 2537.57
Jan 2538.39
Dec 2438.33
Dec 2437.61
Dec 2437.53
Dec 2439.02
Nov 2438.85
Nov 2439.99
Nov 2438.54
Nov 2445.06
Nov 2439.97
Oct 2492.56
Oct 2492.34
Summit Therapeutics Inc.
SMMT
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News: SMMT

Ivonescimab Monotherapy Demonstrates a Statistically Significant & Clinically Meaningful Benefit Compared to Pembrolizumab Monotherapy in PD-L1-Positive Advanced NSCLC in Akeso's HARMONi-2 Study Condu

gurufocus.com · 13 Sep 2026

Ivonescimab Monotherapy Demonstrates a Statistically Significant & Clinically Meaningful Benefit Compared to Pembrolizumab Monotherapy in PD-L1-Positive Advanced NSCLC in Akeso's HARMONi-2 Study Condu

Summit Therapeutics Inc. (NASDAQ: SMMT) today noted that its partner Akeso Inc. [url="]announced[/url] that updated data, including overall survival (OS), from

Ivonescimab Monotherapy Demonstrates a Statistically Significant & Clinically Meaningful Benefit Compared to Pembrolizumab Monotherapy in PD-L1-Positive Advanced NSCLC in Akeso's HARMONi-2 Study Conducted in China

businesswire.com · 13 Sep 2026

Ivonescimab Monotherapy Demonstrates a Statistically Significant & Clinically Meaningful Benefit Compared to Pembrolizumab Monotherapy in PD-L1-Positive Advanced NSCLC in Akeso's HARMONi-2 Study Conducted in China

MIAMI--(BUSINESS WIRE)---- $SMMT--Summit Therapeutics Inc. (NASDAQ: SMMT) today noted that its partner Akeso Inc. announced that updated data, including overall survival (OS), from the randomized, double-blind Phase III HARMONi-2 trial featuring the novel, potential first-in-class investigational bispecific antibody ivonescimab is being presented at the International Association for the Study of Lung Cancer's (IASLC) 2026 World Conference on Lung Cancer (WCLC 2026) in Seoul, Republic of Korea. The HARMON.

Bank of New York Mellon Corp Takes $6.28 Million Position in Summit Therapeutics PLC $SMMT

defenseworld.net · 5 Sep 2026

Bank of New York Mellon Corp Takes $6.28 Million Position in Summit Therapeutics PLC $SMMT

Bank of New York Mellon Corp purchased a new position in Summit Therapeutics PLC (NASDAQ: SMMT) during the undefined quarter, according to its most recent filing with the Securities and Exchange Commission. The fund purchased 431,299 shares of the company's stock, valued at approximately $6,284,000. Bank of New York Mellon Corp owned approximately

SMMT Stock Soars on NSCLC Drug Survival Data Beating Keytruda in China

zacks.com · 4 Sep 2026

SMMT Stock Soars on NSCLC Drug Survival Data Beating Keytruda in China

Summit Therapeutics stock jumps 17% after ivonescimab showed a significant overall survival benefit over Keytruda in a China phase III lung cancer study.

Better Cancer Therapy Than Keytruda? Summit Therapeutics Partner's Ivonescimab Outperforms in Lung Cancer Study

benzinga.com · 3 Sep 2026

Better Cancer Therapy Than Keytruda? Summit Therapeutics Partner's Ivonescimab Outperforms in Lung Cancer Study

Summit Therapeutics Inc. (NASDAQ:SMMT) stock is trading higher on Thursday after its development partner, Akeso Inc., reported highly favorable overall survival data from a late-stage clinical trial.

November 14 Is The Make-Or-Break Moment For Summit Therapeutics' Cancer Bet

seekingalpha.com · 3 Sep 2026

November 14 Is The Make-Or-Break Moment For Summit Therapeutics' Cancer Bet

Summit Therapeutics is positioned as a high-conviction buy into the November 2026 FDA PDUFA decision for ivonescimab in NSCLC. SMMT's ivonescimab demonstrates robust PFS and statistically significant OS benefits in multiple Phase III trials, supporting best-in-class potential versus PD-1 monotherapy. Financials reflect intentional capital deployment, with $690M+ cash and 4–5 quarters of runway to fund late-stage clinical catalysts and regulatory milestones.

Ivonescimab Monotherapy Demonstrates Statistically Significant Overall Survival Benefit Compared to Pembrolizumab Monotherapy in PD-L1-Positive Advanced NSCLC in HARMONi-2 Study Conducted by Akeso in China

businesswire.com · 2 Sep 2026

Ivonescimab Monotherapy Demonstrates Statistically Significant Overall Survival Benefit Compared to Pembrolizumab Monotherapy in PD-L1-Positive Advanced NSCLC in HARMONi-2 Study Conducted by Akeso in China

MIAMI--(BUSINESS WIRE)---- $SMMT--Summit Therapeutics Inc. (NASDAQ: SMMT) today noted that its partner Akeso Inc. announced positive overall survival (OS) results from the randomized, double-blind Phase III HARMONi-2 study evaluating ivonescimab monotherapy against pembrolizumab monotherapy in patients with locally advanced or metastatic non-small cell lung cancer (NSCLC) whose tumors have positive PD-L1 expression. HARMONi-2 (AK112-303) is a single-region, multi-center Phase III study conducted in China.

SMMT Rises on Akeso's Win in Phase III Biliary Tract Cancer Study

zacks.com · 27 Aug 2026

SMMT Rises on Akeso's Win in Phase III Biliary Tract Cancer Study

Summit gains as positive HARMONi-GI1 data show ivonescimab's OS benefit in biliary tract cancer, expanding its potential beyond NSCLC.

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