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ProQR Therapeutics N.V.

$1.86 -$0.13 (-6.53%)
NASDAQ · 14 Sep 2026 20:00 UTC
Previous Close
$1.86
Day Range
$1.81$1.88
Year Range
$1.33$3.1
Market Cap
195.87M
AVG Volume
939.73K
Trailing/Forward PE
-4.07/-
PEG ratio
-0.25
Dividend Yield
-
Next Earnings Date
2026-11-05
Primary Exchange
NASDAQUS
Revenue (EUR)
-10M010M20M2016201720182019202020212022202320242025
PRQR Revenue (EUR) by year
PeriodRevenue (EUR)
202515.94M
202418.91M
20236.59M
20224.36M
20212.26M
20200
20190
20184.94M
2017-1.53M
20162.28M
Net Income (EUR)
-80M-60M-40M-20M02016201720182019202020212022202320242025
PRQR Net Income (EUR) by year
PeriodNet Income (EUR)
2025-42.18M
2024-27.76M
2023-28.12M
2022-64.42M
2021-61.62M
2020-46.56M
2019-56.48M
2018-36.9M
2017-43.64M
2016-39.1M
Operating Income (EUR)
-80M-60M-40M-20M02016201720182019202020212022202320242025
PRQR Operating Income (EUR) by year
PeriodOperating Income (EUR)
2025-43.45M
2024-30.47M
2023-31.86M
2022-65.16M
2021-57.19M
2020-42.37M
2019-57.45M
2018-36.29M
2017-40.5M
2016-39.57M
EBITDA (EUR)
-80M-60M-40M-20M02016201720182019202020212022202320242025
PRQR EBITDA (EUR) by year
PeriodEBITDA (EUR)
2025-37.43M
2024-23.13M
2023-20.12M
2022-60.09M
2021-56.24M
2020-50.45M
2019-51.97M
2018-31.46M
2017-41.86M
2016-36.13M
Cash Flows (EUR)
-75M-50M-25M025M2016201720182019202020212022202320242025
PRQR Cash Flows (EUR) by year
PeriodCash Flows (EUR)
2025-53.81M
2024-37.81M
202320.18M
2022-69.22M
2021-26.5M
2020-47.98M
2019-44.55M
2018-31M
2017-35.07M
2016-36.76M
EPS (EUR)
-2-1.5-1-0.502016201720182019202020212022202320242025
PRQR EPS (EUR) by year
PeriodEPS (EUR)
2025-0.41
2024-0.34
2023-0.34
2022-0.89
2021-0.97
2020-0.92
2019-1.36
2018-1.07
2017-1.73
2016-1.68
Expenses (EUR)
020M40M60M80MR&DSG&ACapex2016201720182019202020212022202320242025
PRQR Expenses (EUR) by year
PeriodExpenses (EUR)
202560.81M
202451.44M
202342.75M
202270.23M
202160.07M
202052.74M
201959.96M
201842.37M
201742.11M
201643.94M
Cash & Debt (EUR)
050M100M150M200MCashLong Term DebtShort Term Debt2016201720182019202020212022202320242025
PRQR Cash & Debt (EUR) by year
PeriodCash & Debt (EUR)
2025108.53M
2024149.41M
2023131.37M
202294.78M
2021187.52M
202092.79M
2019125.66M
2018105.58M
201748.1M
201659.2M
Debt ratios
00.250.50.75120182019202020212022202320242025
PRQR Debt ratios by year
PeriodDebt ratios
20250.65
20240.83
20230.59
20220.33
20210.67
20200.29
20190.68
20180.75
Margins
0%25%50%75%100%201520162017201820212022202320242025
PRQR Margins by year
PeriodMargins
2025100%
2024100%
2023100%
2022100%
202166.31%
2018100%
2017100%
2016100%
2015100%
Return on Capital
-150%-100%-50%0%2016201720182019202020212022202320242025
PRQR Return on Capital by year
PeriodReturn on Capital
2025-72.75%
2024-31.35%
2023-61.5%
2022-96.62%
2021-54.42%
2020-67.3%
2019-53.63%
2018-39.82%
2017-110.97%
2016-73.59%
Shares Outstanding
050M100M150M2016201720182019202020212022202320242025
PRQR Shares Outstanding by year
PeriodShares Outstanding
2025103.01M
202481.67M
202378.46M
202277.39M
202171.24M
202050.17M
201947.37M
201838.81M
201728.7M
201623.35M
Book Value Per Share (EUR)
01232016201720182019202020212022202320242025
PRQR Book Value Per Share (EUR) by year
PeriodBook Value Per Share (EUR)
20250.56
20241.08
20230.58
20220.86
20211.59
20201.38
20192.22
20182.39
20171.37
20162.28
Total Assets (EUR)
0100M200M300M2016201720182019202020212022202320242025
PRQR Total Assets (EUR) by year
PeriodTotal Assets (EUR)
2025132.43M
2024167.96M
2023152.31M
2022171.32M
2021209.58M
2020120.8M
2019131.93M
2018110.23M
201753.1M
201665.54M
Employee Count
0501001502002016201720182019202020212022202320242025
PRQR Employee Count by year
PeriodEmployee Count
2025187
2024166
2023157
2022130
2021182
2020150
2019154
2018118
2017130
2016133
Free Cash Flow Yield
-50%-40%-30%-20%-10%med -24.85%Dec 24Apr 25Jul 25Nov 25Feb 26Jun 26Sep 26
PRQR Free Cash Flow Yield by year
PeriodFree Cash Flow Yield
Sep 26-28.53%
Sep 26-28.53%
Sep 26-25.68%
Aug 26-23.58%
Aug 26-23.26%
Aug 26-28.08%
Aug 26-28.66%
Jul 26-31.24%
Jul 26-30.82%
Jul 26-31.36%
Jul 26-30.76%
Jul 26-29.45%
Jun 26-34.68%
Jun 26-28.27%
Jun 26-37.45%
Jun 26-35.8%
May 26-34.38%
May 26-34.66%
May 26-34.09%
May 26-34.99%
May 26-35.47%
Apr 26-35.48%
Apr 26-27.73%
Apr 26-29.74%
Apr 26-31.67%
Mar 26-39.41%
Mar 26-35.25%
Mar 26-29.48%
Mar 26-30.62%
Feb 26-34.88%
Feb 26-38.38%
Feb 26-38.14%
Feb 26-36.95%
Jan 26-34.32%
Jan 26-31.71%
Jan 26-32.98%
Jan 26-30.84%
Jan 26-27.63%
Dec 25-25.45%
Dec 25-24.85%
Dec 25-23.64%
Dec 25-26.13%
Nov 25-23.25%
Nov 25-26.22%
Nov 25-25.12%
Nov 25-24.44%
Oct 25-17.17%
Oct 25-16.3%
Oct 25-17.09%
Oct 25-19.67%
Oct 25-19.55%
Sep 25-22.61%
Sep 25-22.8%
Sep 25-21.84%
Sep 25-19.51%
Aug 25-21.18%
Aug 25-21.15%
Aug 25-23.28%
Aug 25-21.87%
Aug 25-20.09%
Jul 25-18.99%
Jul 25-18.55%
Jul 25-18.17%
Jul 25-19.45%
Jun 25-20.71%
Jun 25-21.53%
Jun 25-22.16%
Jun 25-21.51%
May 25-24.66%
May 25-24.55%
May 25-24.85%
May 25-25.2%
May 25-26.29%
Apr 25-36.81%
Apr 25-46.19%
Apr 25-46.99%
Apr 25-43.02%
Mar 25-35.86%
Mar 25-30.36%
Mar 25-29.85%
Mar 25-23.79%
Feb 25-18.68%
Feb 25-17.15%
Feb 25-18.19%
Feb 25-19.26%
Jan 25-20.5%
Jan 25-20.38%
Jan 25-18.18%
Jan 25-17.76%
Jan 25-15.67%
Dec 24-15.67%
Dec 24-16.64%
Dec 24-15.57%
Dec 24-12.45%
Nov 24-11.56%
Nov 24-12.08%
Nov 24-11.58%
Nov 24-11.93%
Nov 24-12.87%
Oct 24-13.82%
Price to Sales
05101520med 10.68Dec 24Apr 25Jul 25Nov 25Feb 26Jun 26Sep 26
PRQR Price to Sales by year
PeriodPrice to Sales
Sep 269.49
Sep 269.49
Sep 2610.55
Aug 2615.44
Aug 2615.65
Aug 2612.96
Aug 2612.7
Jul 2611.65
Jul 2611.81
Jul 2611.61
Jul 2611.84
Jul 2612.36
Jun 2610.5
Jun 2612.88
Jun 269.72
Jun 2610.17
May 2610.59
May 2610.5
May 2610.68
May 269.08
May 268.95
Apr 268.95
Apr 2611.45
Apr 2610.68
Apr 2610.03
Mar 268.06
Mar 269.01
Mar 2610.77
Mar 2610.37
Feb 269.1
Feb 268.27
Feb 268.33
Feb 268.59
Jan 269.25
Jan 2610.02
Jan 269.63
Jan 2610.3
Jan 2611.49
Dec 2512.48
Dec 2512.78
Dec 2513.44
Dec 2512.15
Nov 2513.66
Nov 2512.11
Nov 2512.64
Nov 2513
Oct 2515.17
Oct 2515.99
Oct 2515.24
Oct 2513.24
Oct 2513.33
Sep 2511.52
Sep 2511.42
Sep 2511.93
Sep 2513.36
Aug 2512.3
Aug 2512.32
Aug 2511.19
Aug 2511.91
Aug 259.96
Jul 2510.54
Jul 2510.79
Jul 2511.01
Jul 2510.29
Jun 259.66
Jun 259.29
Jun 259.03
Jun 259.3
May 258.12
May 258.15
May 258.05
May 257.94
May 257.61
Apr 255.43
Apr 254.33
Apr 254.26
Apr 254.65
Mar 255.58
Mar 256.59
Mar 256.7
Mar 258.05
Feb 2510.25
Feb 2511.17
Feb 2510.53
Feb 259.95
Jan 259.34
Jan 259.4
Jan 2510.54
Jan 2510.78
Jan 2512.22
Dec 2412.22
Dec 2411.51
Dec 2412.3
Dec 2415.38
Nov 2416.58
Nov 2415.86
Nov 2416.55
Nov 2416.06
Nov 2418.23
Oct 2416.98
Price/Operating Cashflow
0255075100125med 17.11Aug 23Oct 23Nov 23Dec 23Feb 24Mar 24May 24
PRQR Price/Operating Cashflow by year
PeriodPrice/Operating Cashflow
May 246.8
Apr 246.6
Apr 246.8
Apr 247.53
Apr 247.42
Mar 247.73
Mar 248.02
Mar 248.56
Mar 2417.12
Mar 2416.37
Feb 2416.9
Feb 2416.21
Feb 2418.28
Feb 2417.69
Jan 2417.17
Jan 2417.1
Jan 2418.25
Jan 2416.63
Dec 2316.08
Dec 2315.46
Dec 2317.68
Dec 2316.65
Dec 2314.24
Nov 2312.12
Nov 2312.07
Nov 2311.4
Nov 2377.19
Oct 2375.88
Oct 2384.73
Oct 2380.2
Oct 2384.09
Sep 2384.24
Sep 2394.64
Sep 23103.49
Sep 2398.63
Sep 23101.1
Aug 2398.39
Aug 2397.69
Aug 2395.78
Aug 2393.97
Price to Book
051015med 2.72Dec 24Apr 25Jul 25Nov 25Feb 26Jun 26Sep 26
PRQR Price to Book by year
PeriodPrice to Book
Sep 262.22
Sep 262.22
Sep 262.47
Aug 264.81
Aug 264.87
Aug 264.04
Aug 263.96
Jul 263.63
Jul 263.68
Jul 263.61
Jul 263.68
Jul 263.85
Jun 263.27
Jun 264.01
Jun 263.03
Jun 263.17
May 263.3
May 263.27
May 263.32
May 262.11
May 262.08
Apr 262.08
Apr 262.66
Apr 262.48
Apr 262.33
Mar 261.87
Mar 262.09
Mar 262.5
Mar 262.41
Feb 262.11
Feb 261.92
Feb 261.93
Feb 261.99
Jan 262.15
Jan 262.32
Jan 262.23
Jan 262.39
Jan 262.67
Dec 252.9
Dec 252.96
Dec 253.12
Dec 252.82
Nov 253.17
Nov 252.81
Nov 252.93
Nov 253.02
Oct 253.18
Oct 253.35
Oct 253.2
Oct 252.78
Oct 252.79
Sep 252.42
Sep 252.4
Sep 252.5
Sep 252.8
Aug 252.58
Aug 252.58
Aug 252.35
Aug 252.5
Aug 252.22
Jul 252.35
Jul 252.4
Jul 252.45
Jul 252.29
Jun 252.15
Jun 252.07
Jun 252.01
Jun 252.07
May 251.81
May 251.81
May 251.79
May 251.77
May 251.62
Apr 251.16
Apr 250.92
Apr 250.91
Apr 250.99
Mar 251.19
Mar 251.41
Mar 251.43
Mar 255.76
Feb 257.34
Feb 258
Feb 257.54
Feb 257.12
Jan 256.69
Jan 256.73
Jan 257.54
Jan 257.72
Jan 258.75
Dec 248.75
Dec 248.24
Dec 248.81
Dec 2411.01
Nov 2411.86
Nov 2411.35
Nov 2411.84
Nov 2411.5
Nov 248.55
Oct 247.96
ProQR Therapeutics N.V.
PRQR
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News: PRQR

ProQR Announces First Participant Dosed in Phase 1 Study of AX-0811 and Virtual Investor and Analyst Educational Event on September 30, 2026

globenewswire.com · 9 Sep 2026

ProQR Announces First Participant Dosed in Phase 1 Study of AX-0811 and Virtual Investor and Analyst Educational Event on September 30, 2026

LEIDEN, Netherlands & CAMBRIDGE, Mass., Sept. 09, 2026 (GLOBE NEWSWIRE) -- ProQR Therapeutics N.V. (Nasdaq: PRQR) (ProQR), a clinical-stage company dedicated to changing lives through transformative RNA therapies based on its proprietary ADAR-mediated Axiomer™ RNA editing technology platform, today announced that the first participant has been dosed in the Phase 1 clinical trial of AX-0811 in healthy volunteers.

ProQR to Participate in Upcoming Investor Conferences in September 2026

globenewswire.com · 2 Sep 2026

ProQR to Participate in Upcoming Investor Conferences in September 2026

LEIDEN, Netherlands & CAMBRIDGE, Mass., Sept. 02, 2026 (GLOBE NEWSWIRE) -- ProQR Therapeutics N.V.

ProQR Therapeutics: Buy For Axiomer RNA Tech Validation And Other Catalysts

seekingalpha.com · 21 Aug 2026

ProQR Therapeutics: Buy For Axiomer RNA Tech Validation And Other Catalysts

I initiate ProQR Therapeutics N.V. with a Buy rating, driven by strong initial human proof-of-concept for its Axiomer RNA editing platform. The company's AX-0810 achieved 8-fold serum bile acid increases in phase 1, surpassing the 2-fold target and supporting its disease-modifying potential in biliary atresia [BA]. Upcoming catalysts include full phase 1 data for AX-0810 by end-2026, pediatric BA data from China in H1 2027, and phase 1 data for next-gen AX-0811 by end-2026.

ProQR Announces Second Quarter 2026 Operating and Financial Results

globenewswire.com · 13 Aug 2026

ProQR Announces Second Quarter 2026 Operating and Financial Results

LEIDEN, Netherlands & CAMBRIDGE, Mass., Aug. 13, 2026 (GLOBE NEWSWIRE) --  ProQR Therapeutics N.V. (Nasdaq: PRQR) (ProQR), a clinical-stage company dedicated to changing lives through transformative RNA therapies based on its proprietary Axiomer™ RNA editing technology platform, today reported its financial and operating results for the second quarter ended June 30, 2026, and provided a business update.

Contrasting Artiva Biotherapeutics (NASDAQ:ARTV) & ProQR Therapeutics (NASDAQ:PRQR)

defenseworld.net · 11 Aug 2026

Contrasting Artiva Biotherapeutics (NASDAQ:ARTV) & ProQR Therapeutics (NASDAQ:PRQR)

ProQR Therapeutics (NASDAQ: PRQR - Get Free Report) and Artiva Biotherapeutics (NASDAQ: ARTV - Get Free Report) are both small-cap healthcare companies, but which is the superior stock? We will contrast the two companies based on the strength of their risk, analyst recommendations, dividends, institutional ownership, valuation, earnings and profitability. Valuation and Earnings This table compares ProQR

ProQR Therapeutics N.V. (NASDAQ:PRQR) Receives Average Rating of “Moderate Buy” from Analysts

defenseworld.net · 4 Aug 2026

ProQR Therapeutics N.V. (NASDAQ:PRQR) Receives Average Rating of “Moderate Buy” from Analysts

ProQR Therapeutics N.V. (NASDAQ: PRQR - Get Free Report) has received an average rating of "Moderate Buy" from the six brokerages that are currently covering the firm, MarketBeat.com reports. One equities research analyst has rated the stock with a sell recommendation, one has assigned a hold recommendation and four have assigned a buy recommendation to the

ProQR Therapeutics: Human NTCP Data Strengthens The Axiomer Thesis

seekingalpha.com · 4 Jul 2026

ProQR Therapeutics: Human NTCP Data Strengthens The Axiomer Thesis

ProQR Therapeutics (PRQR) has transitioned its RNA editing platform from preclinical promise to demonstrated human pharmacological activity, notably with AX-0810's Phase 1 target engagement data. PRQR differentiates itself by prioritizing NTCP modulation in rare pediatric liver disease (biliary atresia), aiming for a faster, cleaner clinical validation path than competitors. Recent financings, including a $50M direct offering and Eli Lilly's $9.2M investment, extend PRQR's cash runway to mid-2027, supporting multiple clinical programs.

ProQR Prices $50.0 Million Underwritten Registered Direct Offering and Concurrent Private Placement

globenewswire.com · 25 Jun 2026

ProQR Prices $50.0 Million Underwritten Registered Direct Offering and Concurrent Private Placement

LEIDEN, Netherlands and CAMBRIDGE, Mass., June 25, 2026 (GLOBE NEWSWIRE) -- ProQR Therapeutics N.V. (Nasdaq: PRQR) (“ProQR”), a clinical-stage biotechnology company dedicated to changing lives through transformative RNA therapies based on its proprietary Axiomer™ RNA editing technology platform, today announced the pricing of an underwritten registered direct offering of 27,624,310 ordinary shares (the “Offering”) at an offering price of $1.81 per share (the “Offering Price”), for total gross proceeds of approximately $50.0 million, before deducting underwriting discounts and commissions and other offering expenses payable by ProQR.

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