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Phio Pharmaceuticals Corp.

$1.03 -$0.06 (-5.50%)
NASDAQ · 11 Sep 2026 20:00 UTC
Previous Close
$1.01
Day Range
$1.02$1.05
Year Range
$0.81$4.19
Market Cap
11.97M
AVG Volume
476.95K
Trailing/Forward PE
-0.77/-
PEG ratio
0.01
Dividend Yield
-
Next Earnings Date
2026-11-12
Primary Exchange
NASDAQUS
Revenue (USD)
050K100K150K2016201720182019202020212022202320242025
PHIO Revenue (USD) by year
PeriodRevenue (USD)
20250
20240
20230
20220
20210
20200
201921K
2018138K
201715K
201619K
Net Income (USD)
-15M-10M-5M02016201720182019202020212022202320242025
PHIO Net Income (USD) by year
PeriodNet Income (USD)
2025-8.7M
2024-7.15M
2023-10.83M
2022-11.48M
2021-13.29M
2020-8.79M
2019-8.91M
2018-7.36M
2017-12.45M
2016-8.99M
Operating Income (USD)
-15M-10M-5M02016201720182019202020212022202320242025
PHIO Operating Income (USD) by year
PeriodOperating Income (USD)
2025-9.22M
2024-7.39M
2023-10.7M
2022-11.46M
2021-13.51M
2020-8.79M
2019-8.99M
2018-7.36M
2017-12.44M
2016-9.02M
EBITDA (USD)
-15M-10M-5M02016201720182019202020212022202320242025
PHIO EBITDA (USD) by year
PeriodEBITDA (USD)
2025-8.69M
2024-7.07M
2023-10.74M
2022-11.39M
2021-13.44M
2020-8.66M
2019-8.91M
2018-7.28M
2017-13.99M
2016-8.96M
Cash Flows (USD)
-15M-10M-5M02016201720182019202020212022202320242025
PHIO Cash Flows (USD) by year
PeriodCash Flows (USD)
2025-7.99M
2024-7.11M
2023-10.75M
2022-12.25M
2021-11.91M
2020-8.82M
2019-8.72M
2018-7.53M
2017-9.72M
2016-7.76M
EPS (USD)
-80000-60000-40000-2000002016201720182019202020212022202320242025
PHIO EPS (USD) by year
PeriodEPS (USD)
2025-41071.24
2024-9.77
2023-56.52
2022-90.03
2021-113.41
2020-219.3
2019-2113.89
2018-10725.41
2017-33728.44
2016-79345.98
Expenses (USD)
05M10M15MR&DSG&ACapex2016201720182019202020212022202320242025
PHIO Expenses (USD) by year
PeriodExpenses (USD)
20259.23M
20247.39M
202310.66M
202211.58M
202113.56M
20208.72M
20199.06M
20187.51M
20179.58M
20169.17M
Cash & Debt (USD)
010M20M30MCashLong Term Debt2016201720182019202020212022202320242025
PHIO Cash & Debt (USD) by year
PeriodCash & Debt (USD)
202521.03M
20245.38M
20238.49M
202211.78M
202124.06M
202014.24M
20196.93M
201814.88M
20173.58M
201612.91M
Debt ratios
00.20.40.60.820182019202020212022202320242025
PHIO Debt ratios by year
PeriodDebt ratios
20250.55
20240.13
20230.19
20220.27
20210.62
20200.35
20190.16
20180.37
Margins
-40000%-30000%-20000%-10000%0%20152016201720182019
PHIO Margins by year
PeriodMargins
2019-15580.95%
2018-3034.78%
2017-35700%
2016-28400%
2015-20267.65%
Return on Capital
-800%-600%-400%-200%0%2016201720182019202020212022202320242025
PHIO Return on Capital by year
PeriodReturn on Capital
2025-43.17%
2024-151.39%
2023-140.05%
2022-105.9%
2021-60.58%
2020-67.56%
2019-154.98%
2018-54.21%
2017-679.32%
2016-82.86%
Shares Outstanding
05M10M15M2016201720182019202020212022202320242025
PHIO Shares Outstanding by year
PeriodShares Outstanding
202511.62M
2024787.47K
2023415.95K
2022126.43K
2021125.19K
202053.47K
20195.24K
20182.87K
2017400
2016123
Book Value Per Share (USD)
02500050000750001000002016201720182019202020212022202320242025
PHIO Book Value Per Share (USD) by year
PeriodBook Value Per Share (USD)
20251.73
20246
202318.58
202285.74
2021175.18
2020243.45
20191096.53
20184727.72
20174582.5
201688252.03
Total Assets (USD)
010M20M30M2016201720182019202020212022202320242025
PHIO Total Assets (USD) by year
PeriodTotal Assets (USD)
202521.49M
20245.74M
20239.36M
202212.81M
202125.17M
202015.74M
20198.04M
201815.32M
20174.1M
201613.4M
Employee Count
0510152016201720182019202020212022202320242025
PHIO Employee Count by year
PeriodEmployee Count
20256
20245
20238
20229
202112
202010
201911
20189
201715
201615
Free Cash Flow Yield
-1000%-800%-600%-400%-200%0%med -95.31%Dec 24Apr 25Jul 25Oct 25Feb 26May 26Sep 26
PHIO Free Cash Flow Yield by year
PeriodFree Cash Flow Yield
Sep 26-102.03%
Sep 26-97.31%
Aug 26-93%
Aug 26-89.06%
Aug 26-96.42%
Aug 26-101.05%
Jul 26-90.44%
Jul 26-88.7%
Jul 26-89.56%
Jul 26-90.44%
Jul 26-92.25%
Jun 26-95.1%
Jun 26-89.56%
Jun 26-86.22%
Jun 26-87.03%
May 26-83.11%
May 26-84.63%
May 26-86.22%
May 26-86.22%
May 26-60.34%
Apr 26-57.8%
Apr 26-53.32%
Apr 26-56.85%
Apr 26-53.74%
Mar 26-54.59%
Mar 26-56.38%
Mar 26-58.79%
Mar 26-59.3%
Feb 26-116.84%
Feb 26-129.32%
Feb 26-80.73%
Feb 26-144.76%
Jan 26-131.88%
Jan 26-122.2%
Jan 26-116.84%
Jan 26-114.83%
Jan 26-122.2%
Dec 25-123.33%
Dec 25-124.48%
Dec 25-118.93%
Dec 25-101.68%
Nov 25-105.71%
Nov 25-118.93%
Nov 25-102.46%
Nov 25-95.52%
Oct 25-72.69%
Oct 25-70.29%
Oct 25-70.62%
Oct 25-67.73%
Oct 25-62.35%
Sep 25-66.82%
Sep 25-71.99%
Sep 25-68.35%
Sep 25-73.05%
Aug 25-75.64%
Aug 25-71.3%
Aug 25-68.35%
Aug 25-65.82%
Aug 25-63.56%
Jul 25-54.05%
Jul 25-60.45%
Jul 25-64.11%
Jul 25-61.71%
Jun 25-68.25%
Jun 25-65.24%
Jun 25-65.24%
Jun 25-50.03%
May 25-74.05%
May 25-84.63%
May 25-80.49%
May 25-513.23%
May 25-460.86%
Apr 25-442.78%
Apr 25-330.87%
Apr 25-519.12%
Apr 25-844.18%
Mar 25-635.09%
Mar 25-635.09%
Mar 25-635.09%
Mar 25-630.2%
Feb 25-576.95%
Feb 25-490.58%
Feb 25-452.63%
Feb 25-433.47%
Jan 25-397.7%
Jan 25-370.71%
Jan 25-295.76%
Jan 25-484.77%
Jan 25-415.87%
Dec 24-424.49%
Dec 24-465.49%
Dec 24-291.55%
Dec 24-288.47%
Nov 24-301.2%
Nov 24-331.69%
Nov 24-370.71%
Nov 24-601.84%
Nov 24-569.05%
Oct 24-610.11%
Oct 24-610.11%
Price to Sales
0100200300med 59.99Aug 18Nov 18Mar 19Jun 19Oct 19Jan 20May 20
PHIO Price to Sales by year
PeriodPrice to Sales
May 2070.9
May 2050.14
Apr 2050.41
Apr 2051.22
Apr 2047.72
Apr 2045.56
Mar 2056.61
Mar 2047.47
Mar 2044.39
Mar 2067.03
Feb 2064.39
Feb 2069.22
Feb 2066.37
Feb 20163.72
Jan 20202.39
Jan 20202.61
Jan 20225.25
Jan 20255.02
Jan 20231.21
Dec 19177.19
Dec 19175.25
Dec 19163.29
Dec 19175.25
Nov 19172.84
Nov 19163.17
Nov 19229.76
Nov 1980.67
Nov 1971.45
Oct 1968.97
Oct 1965.77
Oct 1966.7
Oct 1971.73
Sep 1986.25
Sep 19102.2
Sep 1997.26
Sep 19101.61
Aug 19100.49
Aug 19102.94
Aug 19107.59
Aug 1956.9
Aug 1959.99
Jul 1959.24
Jul 1959.99
Jul 1957.89
Jul 1956.99
Jun 1956.99
Jun 1958.12
Jun 1959.08
Jun 1960.41
May 1964.49
May 1965.24
May 1968.39
May 1956.82
May 1959.96
Apr 1961.19
Apr 1956.74
Apr 1954.64
Apr 1959.34
Mar 1955.63
Mar 1912.13
Mar 1911.98
Mar 1910.56
Mar 1910.84
Feb 1910.7
Feb 1910.37
Feb 1910.53
Feb 1910.76
Jan 1910.27
Jan 199.74
Jan 1910.27
Jan 199.98
Dec 188.85
Dec 188.42
Dec 189.84
Dec 1810.56
Nov 189.42
Nov 188.91
Nov 189.42
Nov 1818.46
Nov 1818.05
Oct 1818.64
Oct 1818.76
Oct 1820.03
Oct 1826.64
Sep 1849.88
Sep 1851.16
Sep 1855
Sep 1863.95
Aug 1866.08
Aug 1864.8
Aug 1865.23
Aug 18107.09
Aug 18111.34
Jul 1896.28
Jul 18118.55
Jul 18129.68
Jul 18129.03
Jun 18126.41
Jun 18142.13
Jun 18153.26
Price to Book
00.250.50.7511.25med 0.7Dec 24Apr 25Jul 25Oct 25Feb 26May 26Sep 26
PHIO Price to Book by year
PeriodPrice to Book
Sep 260.95
Sep 261
Aug 261.04
Aug 261.09
Aug 261
Aug 260.96
Jul 260.72
Jul 260.73
Jul 260.73
Jul 260.72
Jul 260.71
Jun 260.68
Jun 260.73
Jun 260.76
Jun 260.75
May 260.78
May 260.77
May 260.76
May 260.76
May 260.66
Apr 260.69
Apr 260.74
Apr 260.7
Apr 260.74
Mar 260.73
Mar 260.7
Mar 260.67
Mar 260.67
Feb 260.63
Feb 260.57
Feb 260.92
Feb 260.51
Jan 260.56
Jan 260.61
Jan 260.63
Jan 260.64
Jan 260.61
Dec 250.6
Dec 250.59
Dec 250.62
Dec 250.73
Nov 250.7
Nov 250.62
Nov 250.72
Nov 250.74
Oct 250.97
Oct 251.01
Oct 251
Oct 251.04
Oct 251.14
Sep 251.06
Sep 250.98
Sep 251.04
Sep 250.97
Aug 250.94
Aug 250.99
Aug 251.04
Aug 250.8
Aug 250.82
Jul 250.97
Jul 250.87
Jul 250.82
Jul 250.85
Jun 250.77
Jun 250.8
Jun 250.8
Jun 251.05
May 250.71
May 250.62
May 250.65
May 250.29
May 250.33
Apr 250.34
Apr 250.46
Apr 250.29
Apr 250.18
Mar 250.26
Mar 250.26
Mar 250.26
Mar 250.26
Feb 250.28
Feb 250.33
Feb 250.36
Feb 250.38
Jan 250.41
Jan 250.44
Jan 250.55
Jan 250.34
Jan 250.39
Dec 240.39
Dec 240.35
Dec 240.56
Dec 240.57
Nov 240.54
Nov 240.49
Nov 240.44
Nov 240.4
Nov 240.42
Oct 240.39
Oct 240.39
Phio Pharmaceuticals Corp.
PHIO
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News: PHIO

Phio Pharmaceuticals to Participate in the H.C. Wainwright 28th Annual Global Investment Conference

newsfilecorp.com · 11 Sep 2026

Phio Pharmaceuticals to Participate in the H.C. Wainwright 28th Annual Global Investment Conference

Management to Meet with Investors and Highlight Progress and Future Development Plans for PH-762 King of Prussia, Pennsylvania--(Newsfile Corp. - September 11, 2026) - Phio Pharmaceuticals Corp. (NASDAQ: PHIO), a clinical-stage biotechnology company developing therapeutics based on its proprietary INTASYL® siRNA gene-silencing technology designed to eliminate cancer, today announced that members of its management team will be available for one-on-one investor meetings at the H.C. Wainwright 28th Annual Global Investment Conference, taking place September 14-16, 2026, at the Lotte New York Palace Hotel in New York City.

Phio Pharmaceuticals Secures U.S. Notice of Allowance for INTASYL Composition Selectively Targeting BRD4 Protein with Compound PH-894

feeds.newsfilecorp.com · 11 Aug 2026

Phio Pharmaceuticals Secures U.S. Notice of Allowance for INTASYL Composition Selectively Targeting BRD4 Protein with Compound PH-894

King of Prussia, Pennsylvania--(Newsfile Corp. - August 11, 2026) - Phio Pharmaceuticals Corp. (NASDAQ: PHIO), a clinical-stage biotechnology company developing

Phio Pharmaceuticals Reports Second Quarter 2026 Financial Results and Business Update

newsfilecorp.com · 6 Aug 2026

Phio Pharmaceuticals Reports Second Quarter 2026 Financial Results and Business Update

Strategic milestone advancements for lead clinical candidate PH-762 Initiation of commercial scale API, long term non-clinical toxicology, completion of Phase 1b pharmacology, and new IP announcements King of Prussia, Pennsylvania--(Newsfile Corp. - August 6, 2026) - Phio Pharmaceuticals Corp. (NASDAQ: PHIO) is a clinical-stage siRNA biopharmaceutical company developing therapeutics using its proprietary INTASYL® gene silencing technology to eliminate cancer. Phio today reported its financial results for the quarter ended June 30, 2026, and provided a business update.

Correction to Announcement Regarding Phio Pharmaceuticals Participation in the Renmark Financial Communications Live Virtual Non-Deal Roadshow Series

newsfilecorp.com · 22 Jul 2026

Correction to Announcement Regarding Phio Pharmaceuticals Participation in the Renmark Financial Communications Live Virtual Non-Deal Roadshow Series

Live Presentation and Q&A: Tuesday, July 28, 2026 12 PM EDT King of Prussia, Pennsylvania--(Newsfile Corp. - July 22, 2026) - Phio Pharmaceuticals Corp. (NASDAQ: PHIO) is a clinical-stage siRNA biopharmaceutical company developing therapeutics using its proprietary INTASYL® gene silencing technology to eliminate cancer. Phio Pharmaceuticals announced today that Robert Bitterman, CEO and Chairman of the Board, will present an overview of the Company's INTASYL® siRNA platform, including its lead clinical candidate PH-762 for the treatment of cutaneous carcinomas.

Phio Pharmaceuticals Announces Participation in the Renmark Financial Communications Live Virtual Non-Deal Roadshow Series

newsfilecorp.com · 22 Jul 2026

Phio Pharmaceuticals Announces Participation in the Renmark Financial Communications Live Virtual Non-Deal Roadshow Series

Live Presentation and Q&A: Thursday, July 28, 2026 12 PM EDT King of Prussia, Pennsylvania--(Newsfile Corp. - July 22, 2026) - Phio Pharmaceuticals Corp. (NASDAQ: PHIO) is a clinical-stage siRNA biopharmaceutical company developing therapeutics using its proprietary INTASYL® gene silencing technology to eliminate cancer. Phio Pharmaceuticals announced today that Robert Bitterman, CEO and Chairman of the Board, will present an overview of the Company's INTASYL® siRNA platform, including its lead clinical candidate PH-762 for the treatment of cutaneous carcinomas.

Phio Pharmaceuticals Announces Appointment of Dr. R. Todd Plott to the Board of Directors

newsfilecorp.com · 21 Jul 2026

Phio Pharmaceuticals Announces Appointment of Dr. R. Todd Plott to the Board of Directors

Brings extensive experience in patient care, dermatologic research and commercialization King of Prussia, Pennsylvania--(Newsfile Corp. - July 21, 2026) - Phio Pharmaceuticals Corp. (NASDAQ: PHIO) is a clinical-stage siRNA biopharmaceutical company developing therapeutics using its proprietary INTASYL® gene silencing technology to eliminate cancer. Phio is pleased to announce that R.

Phio Pharmaceuticals Announces Patent Milestone with Multiple Notices of Allowance and Grant Decision

newsfilecorp.com · 15 Jul 2026

Phio Pharmaceuticals Announces Patent Milestone with Multiple Notices of Allowance and Grant Decision

Securing additional patent protection in the United States, Canada, and Japan for INTASYL Compounds King of Prussia, Pennsylvania--(Newsfile Corp. - July 15, 2026) - Phio Pharmaceuticals Corp. (NASDAQ: PHIO) is a clinical-stage siRNA biopharmaceutical company developing therapeutics using its proprietary INTASYL® gene silencing technology to eliminate cancer. Phio Pharmaceuticals announced today significant progress in the protection of its proprietary innovations across key international markets.

Phio Pharmaceuticals Announces Participation in the Renmark Financial Communications Live Virtual Non-Deal Roadshow Series

newsfilecorp.com · 26 Jun 2026

Phio Pharmaceuticals Announces Participation in the Renmark Financial Communications Live Virtual Non-Deal Roadshow Series

Live Presentation and Q&A: Tuesday, June 30, 2026 12 PM EDT King of Prussia, Pennsylvania--(Newsfile Corp. - June 26, 2026) - Phio Pharmaceuticals Corp. (NASDAQ: PHIO) is a clinical-stage siRNA biopharmaceutical company developing therapeutics using its proprietary INTASYL® gene silencing technology to eliminate cancer. Phio Pharmaceuticals announced today that Robert Bitterman, CEO and Chairman of the Board, will present an overview of the Company's INTASYL® siRNA platform, including its lead clinical candidate PH-762 for the treatment of cutaneous carcinomas.

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