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Puma Biotechnology, Inc.

$9.14 +$3.37 (+58.41%)
NASDAQ · 14 Sep 2026 17:55 UTC
Previous Close
$9.12
Day Range
$9.03$9.23
Year Range
$4.3$9.74
Market Cap
465.22M
AVG Volume
315.19K
Trailing/Forward PE
17.01/45.7
PEG ratio
-0.36
Dividend Yield
-
Next Earnings Date
2026-11-05
Primary Exchange
NASDAQUS
Revenue (USD)
0100M200M300M2016201720182019202020212022202320242025
PBYI Revenue (USD) by year
PeriodRevenue (USD)
2025228.37M
2024230.47M
2023235.64M
2022228.03M
2021253.16M
2020225.11M
2019272.34M
2018250.98M
201727.68M
20160
Net Income (USD)
-300M-200M-100M0100M2016201720182019202020212022202320242025
PBYI Net Income (USD) by year
PeriodNet Income (USD)
202531.11M
202430.28M
202321.59M
20222K
2021-29.03M
2020-59.99M
2019-75.62M
2018-113.58M
2017-291.98M
2016-276.05M
Operating Income (USD)
-300M-200M-100M0100M2016201720182019202020212022202320242025
PBYI Operating Income (USD) by year
PeriodOperating Income (USD)
202537.3M
202430.97M
202332.64M
202223.72M
2021-29.02M
2020-30.4M
2019-58.98M
2018-94.74M
2017-292.42M
2016-276.63M
EBITDA (USD)
-300M-200M-100M0100M2016201720182019202020212022202320242025
PBYI EBITDA (USD) by year
PeriodEBITDA (USD)
202553.34M
202448.08M
202346.79M
202221.64M
2021-5.3M
2020-35.71M
2019-52.5M
2018-95.23M
2017-288.47M
2016-275.45M
Cash Flows (USD)
-300M-200M-100M0100M2016201720182019202020212022202320242025
PBYI Cash Flows (USD) by year
PeriodCash Flows (USD)
202541.73M
202438.86M
202314.37M
2022-22.83M
202120.65M
2020-9.27M
201922.1M
2018-24.66M
2017-222.9M
2016-148.97M
EPS (USD)
-10-7.5-5-2.502.52016201720182019202020212022202320242025
PBYI EPS (USD) by year
PeriodEPS (USD)
20250.61
20240.61
20230.45
20220
2021-0.72
2020-1.52
2019-1.95
2018-2.99
2017-7.85
2016-8.3
Expenses (USD)
0100M200M300M400MR&DSG&ACapex2016201720182019202020212022202320242025
PBYI Expenses (USD) by year
PeriodExpenses (USD)
2025133.35M
2024135.6M
2023151.82M
2022149.22M
2021188.06M
2020226.18M
2019273.6M
2018311.82M
2017364.91M
2016283.91M
Cash & Debt (USD)
050M100M150M200MCashLong Term DebtShort Term Debt2016201720182019202020212022202320242025
PBYI Cash & Debt (USD) by year
PeriodCash & Debt (USD)
202597.53M
2024100.97M
202395.94M
202281.07M
202182.11M
202093.39M
2019111.64M
2018108.4M
201781.7M
2016194.5M
Debt ratios
-0.500.5120182019202020212022202320242025
PBYI Debt ratios by year
PeriodDebt ratios
2025-0.41
2024-0.24
20230.57
2022-0.46
2021-0.18
2020-0.06
2019-0.01
2018-0.05
Margins
0%25%50%75%100%201720182019202020212022202320242025
PBYI Margins by year
PeriodMargins
202574.53%
202472.06%
202373.4%
202275.84%
202174.84%
202082.51%
201986.47%
201886.25%
201779.67%
Return on Capital
-1000%-500%0%500%1000%1500%2016201720182019202020212022202320242025
PBYI Return on Capital by year
PeriodReturn on Capital
202523.87%
202432.87%
202340.4%
20220.01%
20211186.67%
20201008.15%
2019-433.05%
2018-331.08%
2017-547.8%
2016-131.58%
Shares Outstanding
020M40M60M2016201720182019202020212022202320242025
PBYI Shares Outstanding by year
PeriodShares Outstanding
202550.34M
202449.1M
202347.6M
202245.81M
202140.99M
202039.46M
201939.04M
201838.2M
201737.51M
201635.69M
Book Value Per Share (USD)
-202462016201720182019202020212022202320242025
PBYI Book Value Per Share (USD) by year
PeriodBook Value Per Share (USD)
20252.59
20241.88
20231.12
20220.47
2021-0.06
2020-0.15
20190.45
20180.9
20171.42
20165.88
Total Assets (USD)
0100M200M300M2016201720182019202020212022202320242025
PBYI Total Assets (USD) by year
PeriodTotal Assets (USD)
2025216.3M
2024213.33M
2023230.53M
2022222.06M
2021226.59M
2020244.22M
2019234.91M
2018259.12M
2017165.53M
2016252.79M
Employee Count
01002003004002016201720182019202020212022202320242025
PBYI Employee Count by year
PeriodEmployee Count
2025179
2024172
2023185
2022192
2021196
2020267
2019269
2018272
2017318
2016160
PE Ratio
05101520med 6.62Dec 24Apr 25Jul 25Oct 25Feb 26May 26Sep 26
PBYI PE Ratio by year
PeriodPE Ratio
Sep 2617.39
Sep 2618.21
Aug 2617.27
Aug 2617.62
Aug 2616.84
Aug 2616.99
Jul 2616.54
Jul 2616.64
Jul 2617.79
Jul 2616.68
Jul 2617.22
Jun 2616.91
Jun 2615.76
Jun 2615.28
Jun 2614.66
May 2614.95
May 2614.76
May 2614.43
May 2615.62
May 2612.12
Apr 2612.2
Apr 2612.09
Apr 2612.59
Apr 2611.16
Mar 269.84
Mar 269.9
Mar 269.55
Mar 269.79
Feb 269.22
Feb 269.3
Feb 269.28
Feb 269.45
Jan 268.82
Jan 268.74
Jan 268.67
Jan 268.32
Jan 267.85
Dec 258.39
Dec 257.66
Dec 257.98
Dec 257.22
Nov 256.87
Nov 256.66
Nov 256.66
Nov 258.15
Oct 255.23
Oct 255.36
Oct 255.61
Oct 255.25
Oct 255.26
Sep 254.96
Sep 254.53
Sep 254.59
Sep 255.16
Aug 255.17
Aug 255.39
Aug 255.88
Aug 253.79
Aug 254
Jul 254.27
Jul 254.43
Jul 254.42
Jul 254.66
Jun 254.34
Jun 254.17
Jun 254.36
Jun 254.85
May 254.27
May 254.22
May 254.42
May 253.79
May 255.2
Apr 254.86
Apr 254.64
Apr 254.57
Apr 254.7
Mar 255.09
Mar 255.69
Mar 255.38
Mar 255.69
Feb 255.8
Feb 256.14
Feb 256.03
Feb 255.86
Jan 256.09
Jan 256.24
Jan 256.26
Jan 256.98
Jan 256.22
Dec 246.49
Dec 245.8
Dec 246.07
Dec 246.58
Nov 247.15
Nov 246.33
Nov 245.1
Nov 246.07
Nov 2416.34
Oct 2416.34
Oct 2415.95
Free Cash Flow Yield
5%10%15%20%25%30%med 17.4%Dec 24Apr 25Jul 25Oct 25Feb 26May 26Sep 26
PBYI Free Cash Flow Yield by year
PeriodFree Cash Flow Yield
Sep 268.86%
Sep 268.46%
Aug 268.92%
Aug 268.74%
Aug 269.15%
Aug 269.07%
Jul 2613.29%
Jul 2613.21%
Jul 2612.36%
Jul 2613.18%
Jul 2612.76%
Jun 2613%
Jun 2613.94%
Jun 2614.38%
Jun 2614.99%
May 2614.7%
May 2614.89%
May 2615.23%
May 2614.07%
May 2611.07%
Apr 2610.99%
Apr 2611.1%
Apr 2610.66%
Apr 2612.01%
Mar 2613.63%
Mar 2613.55%
Mar 2614.05%
Mar 2613.7%
Feb 2614.54%
Feb 2612.47%
Feb 2612.49%
Feb 2612.27%
Jan 2613.14%
Jan 2613.26%
Jan 2613.37%
Jan 2613.94%
Jan 2614.76%
Dec 2513.82%
Dec 2515.13%
Dec 2514.53%
Dec 2516.07%
Nov 2516.86%
Nov 2517.41%
Nov 2517.41%
Nov 2514.22%
Oct 2517.45%
Oct 2517.01%
Oct 2516.27%
Oct 2517.38%
Oct 2517.34%
Sep 2518.38%
Sep 2520.13%
Sep 2519.91%
Sep 2517.69%
Aug 2517.65%
Aug 2516.95%
Aug 2515.53%
Aug 2524.11%
Aug 2520.47%
Jul 2519.16%
Jul 2518.48%
Jul 2518.54%
Jul 2517.55%
Jun 2518.87%
Jun 2519.64%
Jun 2518.76%
Jun 2516.89%
May 2519.16%
May 2519.4%
May 2518.54%
May 2521.6%
May 2524.66%
Apr 2526.39%
Apr 2527.68%
Apr 2528.07%
Apr 2527.3%
Mar 2525.21%
Mar 2522.55%
Mar 2523.84%
Mar 2522.55%
Feb 2522.11%
Feb 2523.62%
Feb 2524.03%
Feb 2524.72%
Jan 2523.78%
Jan 2523.22%
Jan 2523.14%
Jan 2520.76%
Jan 2523.3%
Dec 2422.31%
Dec 2424.99%
Dec 2423.86%
Dec 2422.03%
Nov 2420.27%
Nov 2422.91%
Nov 2428.4%
Nov 2423.86%
Nov 2423.34%
Oct 2423.34%
Oct 2423.91%
Price to Sales
00.511.522.5med 1.07Dec 24Apr 25Jul 25Oct 25Feb 26May 26Sep 26
PBYI Price to Sales by year
PeriodPrice to Sales
Sep 262.01
Sep 262.1
Aug 262
Aug 262.04
Aug 261.95
Aug 261.96
Jul 261.77
Jul 261.79
Jul 261.91
Jul 261.79
Jul 261.85
Jun 261.82
Jun 261.69
Jun 261.64
Jun 261.57
May 261.6
May 261.58
May 261.55
May 261.68
May 261.65
Apr 261.66
Apr 261.65
Apr 261.71
Apr 261.52
Mar 261.34
Mar 261.35
Mar 261.3
Mar 261.33
Feb 261.26
Feb 261.62
Feb 261.62
Feb 261.65
Jan 261.54
Jan 261.52
Jan 261.51
Jan 261.45
Jan 261.37
Dec 251.46
Dec 251.34
Dec 251.39
Dec 251.26
Nov 251.2
Nov 251.16
Nov 251.16
Nov 251.42
Oct 251.06
Oct 251.09
Oct 251.14
Oct 251.07
Oct 251.07
Sep 251.01
Sep 250.92
Sep 250.93
Sep 251.05
Aug 251.05
Aug 251.1
Aug 251.2
Aug 250.77
Aug 250.65
Jul 250.7
Jul 250.72
Jul 250.72
Jul 250.76
Jun 250.71
Jun 250.68
Jun 250.71
Jun 250.79
May 250.7
May 250.69
May 250.72
May 250.62
May 250.68
Apr 250.64
Apr 250.61
Apr 250.6
Apr 250.62
Mar 250.67
Mar 250.75
Mar 250.71
Mar 250.75
Feb 250.76
Feb 250.59
Feb 250.58
Feb 250.56
Jan 250.58
Jan 250.6
Jan 250.6
Jan 250.67
Jan 250.59
Dec 240.62
Dec 240.55
Dec 240.58
Dec 240.63
Nov 240.68
Nov 240.6
Nov 240.49
Nov 240.58
Nov 240.65
Oct 240.65
Oct 240.63
EV/EBITDA
246810med 3.47Dec 24Apr 25Jul 25Oct 25Feb 26May 26Sep 26
PBYI EV/EBITDA by year
PeriodEV/EBITDA
Sep 267.88
Sep 268.34
Aug 267.81
Aug 268.01
Aug 267.57
Aug 267.65
Jul 267.07
Jul 267.13
Jul 267.75
Jul 267.15
Jul 267.45
Jun 267.28
Jun 266.65
Jun 266.39
Jun 266.05
May 266.21
May 266.11
May 265.93
May 266.57
May 265.78
Apr 265.82
Apr 265.76
Apr 266.05
Apr 265.22
Mar 264.44
Mar 264.48
Mar 264.27
Mar 264.42
Feb 264.09
Feb 265.79
Feb 265.78
Feb 265.9
Jan 265.44
Jan 265.38
Jan 265.33
Jan 265.07
Jan 264.73
Dec 255.12
Dec 254.59
Dec 254.82
Dec 254.26
Nov 254
Nov 253.84
Nov 253.84
Nov 254.95
Oct 253.27
Oct 253.37
Oct 253.56
Oct 253.28
Oct 253.29
Sep 253.06
Sep 252.73
Sep 252.77
Sep 253.21
Aug 253.22
Aug 253.38
Aug 253.76
Aug 252.16
Aug 252.21
Jul 252.4
Jul 252.51
Jul 252.5
Jul 252.67
Jun 252.45
Jun 252.33
Jun 252.46
Jun 252.8
May 252.4
May 252.36
May 252.5
May 252.07
May 252.72
Apr 252.5
Apr 252.36
Apr 252.32
Apr 252.4
Mar 252.65
Mar 253.03
Mar 252.83
Mar 253.03
Feb 253.1
Feb 252.72
Feb 252.67
Feb 252.59
Jan 252.7
Jan 252.77
Jan 252.78
Jan 253.12
Jan 252.76
Dec 242.89
Dec 242.56
Dec 242.69
Dec 242.93
Nov 243.2
Nov 242.81
Nov 242.22
Nov 242.69
Nov 244.2
Oct 244.2
Oct 244.1
Price/Operating Cashflow
2.557.51012.5med 5.73Dec 24Apr 25Jul 25Oct 25Feb 26May 26Sep 26
PBYI Price/Operating Cashflow by year
PeriodPrice/Operating Cashflow
Sep 2611.29
Sep 2611.82
Aug 2611.22
Aug 2611.44
Aug 2610.93
Aug 2611.03
Jul 267.52
Jul 267.57
Jul 268.09
Jul 267.59
Jul 267.83
Jun 267.69
Jun 267.17
Jun 266.95
Jun 266.67
May 266.8
May 266.72
May 266.56
May 267.1
May 269.02
Apr 269.08
Apr 269
Apr 269.37
Apr 268.31
Mar 267.32
Mar 267.37
Mar 267.1
Mar 267.29
Feb 266.86
Feb 268
Feb 267.99
Feb 268.13
Jan 267.59
Jan 267.52
Jan 267.46
Jan 267.15
Jan 266.76
Dec 257.21
Dec 256.59
Dec 256.86
Dec 256.21
Nov 255.91
Nov 255.73
Nov 255.73
Nov 257.01
Oct 255.72
Oct 255.86
Oct 256.13
Oct 255.74
Oct 255.75
Sep 255.43
Sep 254.95
Sep 255.01
Sep 255.64
Aug 255.65
Aug 255.88
Aug 256.42
Aug 254.14
Aug 254.87
Jul 255.2
Jul 255.39
Jul 255.37
Jul 255.68
Jun 255.28
Jun 255.07
Jun 255.31
Jun 255.9
May 255.2
May 255.14
May 255.37
May 254.61
May 254.05
Apr 253.78
Apr 253.61
Apr 253.56
Apr 253.66
Mar 253.96
Mar 254.43
Mar 254.19
Mar 254.43
Feb 254.52
Feb 254.22
Feb 254.15
Feb 254.03
Jan 254.19
Jan 254.3
Jan 254.31
Jan 254.8
Jan 254.28
Dec 244.47
Dec 243.99
Dec 244.18
Dec 244.53
Nov 244.92
Nov 244.35
Nov 243.51
Nov 244.18
Nov 244.27
Oct 244.27
Oct 244.17
Price to Book
1234med 2.34Dec 24Apr 25Jul 25Oct 25Feb 26May 26Sep 26
PBYI Price to Book by year
PeriodPrice to Book
Sep 263.35
Sep 263.51
Aug 263.33
Aug 263.4
Aug 263.25
Aug 263.28
Jul 263.14
Jul 263.16
Jul 263.38
Jul 263.17
Jul 263.27
Jun 263.21
Jun 262.99
Jun 262.9
Jun 262.78
May 262.84
May 262.8
May 262.74
May 262.97
May 262.89
Apr 262.91
Apr 262.89
Apr 263
Apr 262.66
Mar 262.35
Mar 262.36
Mar 262.28
Mar 262.34
Feb 262.2
Feb 262.98
Feb 262.98
Feb 263.03
Jan 262.83
Jan 262.8
Jan 262.78
Jan 262.67
Jan 262.52
Dec 252.69
Dec 252.46
Dec 252.56
Dec 252.31
Nov 252.21
Nov 252.14
Nov 252.14
Nov 252.62
Oct 252.42
Oct 252.48
Oct 252.6
Oct 252.43
Oct 252.43
Sep 252.3
Sep 252.1
Sep 252.12
Sep 252.39
Aug 252.39
Aug 252.49
Aug 252.72
Aug 251.75
Aug 251.57
Jul 251.68
Jul 251.74
Jul 251.73
Jul 251.83
Jun 251.7
Jun 251.63
Jun 251.71
Jun 251.9
May 251.68
May 251.65
May 251.73
May 251.49
May 251.71
Apr 251.6
Apr 251.52
Apr 251.5
Apr 251.55
Mar 251.67
Mar 251.87
Mar 251.77
Mar 251.87
Feb 251.91
Feb 252.01
Feb 251.97
Feb 251.92
Jan 251.99
Jan 252.04
Jan 252.05
Jan 252.28
Jan 252.03
Dec 242.12
Dec 241.9
Dec 241.99
Dec 242.15
Nov 242.34
Nov 242.07
Nov 241.67
Nov 241.99
Nov 242.94
Oct 242.94
Oct 242.87
Puma Biotechnology, Inc.
PBYI
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News: PBYI

Puma Biotechnology to Present at H.C. Wainwright's 28th Annual Global Investment Conference

businesswire.com · 9 Sep 2026

Puma Biotechnology to Present at H.C. Wainwright's 28th Annual Global Investment Conference

LOS ANGELES--(BUSINESS WIRE)--On Sept. 14, 2026, Puma Biotechnology CEO Alan Auerbach will present a corporate overview at H.C. Wainwright's 28th Annual Global Investment Conf.

Puma Biotechnology: NERLYNX Funds Their Potential Next Oncology Franchise

seekingalpha.com · 8 Sep 2026

Puma Biotechnology: NERLYNX Funds Their Potential Next Oncology Franchise

NERLYNX gives PBYI an established revenue stream that can support alisertib's development into a potential second oncology franchise. Currently, PBYI already has positive cash flows and a healthy balance sheet, which I believe should give them flexibility as their R&D progresses. Alisertib's biomarker strategy could identify responsive patients, but bear in mind that it's still a speculative asset in Phase 2 trials.

Puma Biotechnology Reports Inducement Awards Under Nasdaq Listing Rule 5635(c)(4)

businesswire.com · 3 Sep 2026

Puma Biotechnology Reports Inducement Awards Under Nasdaq Listing Rule 5635(c)(4)

LOS ANGELES--(BUSINESS WIRE)--Puma Biotechnology reported its inducement awards granted in August 2026, as required under Nasdaq Listing Rule 5635(c)(4).

3,804,736 Shares in Puma Biotechnology, Inc. $PBYI Bought by BlackRock Inc.

defenseworld.net · 2 Sep 2026

3,804,736 Shares in Puma Biotechnology, Inc. $PBYI Bought by BlackRock Inc.

BlackRock Inc. bought a new stake in Puma Biotechnology, Inc. (NASDAQ: PBYI) during the second quarter, according to the company in its most recent Form 13F filing with the Securities and Exchange Commission. The institutional investor bought 3,804,736 shares of the biopharmaceutical company's stock, valued at approximately $30,856,000. BlackRock Inc. owned 7.47% of

Is Puma Biotechnology (PBYI) a Great Value Stock Right Now?

zacks.com · 12 Aug 2026

Is Puma Biotechnology (PBYI) a Great Value Stock Right Now?

Here at Zacks, our focus is on the proven Zacks Rank system, which emphasizes earnings estimates and estimate revisions to find great stocks. Nevertheless, we are always paying attention to the latest value, growth, and momentum trends to underscore strong picks.

PBYI Q2 Earnings & Sales Beat Estimates, 2026 Guidance Raised

zacks.com · 7 Aug 2026

PBYI Q2 Earnings & Sales Beat Estimates, 2026 Guidance Raised

Puma Biotechnology tops Q2 earnings and revenue estimates, raises its 2026 guidance, and outlines upcoming alisertib study milestones as Nerlynx sales climb.

Puma Biotechnology, Inc. (PBYI) Q2 2026 Earnings Call Transcript

seekingalpha.com · 7 Aug 2026

Puma Biotechnology, Inc. (PBYI) Q2 2026 Earnings Call Transcript

Puma Biotechnology, Inc. (PBYI) Q2 2026 Earnings Call Transcript

Puma Biotechnology Q2 Earnings Call Highlights

marketbeat.com · 7 Aug 2026

Puma Biotechnology Q2 Earnings Call Highlights

Puma Biotechnology NASDAQ: PBYI reported second-quarter 2026 total revenue of $56.5 million, including $53.6 million in net product revenue from NERLYNX and $2.9 million in royalty revenue. The company posted GAAP net income of $8.2 million, or $0.16 per diluted share, compared with a net loss of $3.8 million, or $0.07 per share, in the first quarter.

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