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Palisade Bio, Inc.

$2.06 -$0.44 (-17.60%)
NASDAQ · 11 Sep 2026 20:00 UTC
Previous Close
$2.01
Day Range
$2.02$2.1
Year Range
$0.55$2.86
Market Cap
357.57M
AVG Volume
2.82M
Trailing/Forward PE
-3.88/-
PEG ratio
-0.16
Dividend Yield
-
Next Earnings Date
2026-11-09
Primary Exchange
NASDAQUS
Revenue (USD)
0100K200K300K2016201720182019202020212022202320242025
PALI Revenue (USD) by year
PeriodRevenue (USD)
20250
20240
2023250K
20220
20210
20208.52K
201915.39K
2018260K
2017260K
201616.25K
Net Income (USD)
-30M-20M-10M02016201720182019202020212022202320242025
PALI Net Income (USD) by year
PeriodNet Income (USD)
2025-16.78M
2024-14.44M
2023-12.3M
2022-14.26M
2021-26.62M
2020-10.32M
2019-9.17M
2018-4.92M
2017-15.67M
2016-21.07M
Operating Income (USD)
-60M-40M-20M02016201720182019202020212022202320242025
PALI Operating Income (USD) by year
PeriodOperating Income (USD)
2025-18.06M
2024-14.86M
2023-13.07M
2022-15.72M
2021-41.85M
2020-9.3M
2019-8.63M
2018-8.26M
2017-13.31M
2016-20.64M
EBITDA (USD)
-30M-20M-10M02016201720182019202020212022202320242025
PALI EBITDA (USD) by year
PeriodEBITDA (USD)
2025-18.05M
2024-14.42M
2023-12.24M
2022-14.15M
2021-24.04M
2020-9.99M
2019-9.2M
2018-4.73M
2017-15.22M
2016-19.6M
Cash Flows (USD)
-20M-15M-10M-5M02016201720182019202020212022202320242025
PALI Cash Flows (USD) by year
PeriodCash Flows (USD)
2025-10.85M
2024-12.19M
2023-11.14M
2022-13.37M
2021-12.08M
2020-4.77M
2019-7.1M
2018-7.69M
2017-13.43M
2016-15.78M
EPS (USD)
-4000-3000-2000-100002016201720182019202020212022202320242025
PALI EPS (USD) by year
PeriodEPS (USD)
2025-1.48
2024-10.62
2023-23.76
2022-79.68
2021-3054.62
2020-43.48
2019-35.7
2018-21.44
2017-86.56
2016-165.45
Expenses (USD)
-10M010M20M30MR&DSG&ACapex2016201720182019202020212022202320242025
PALI Expenses (USD) by year
PeriodExpenses (USD)
202518.06M
202414.86M
202313.1M
202215.32M
202111.74M
20209.36M
20198.89M
20188.52M
201713.58M
201620.82M
Cash & Debt (USD)
050M100M150MCashLong Term DebtShort Term Debt2016201720182019202020212022202320242025
PALI Cash & Debt (USD) by year
PeriodCash & Debt (USD)
2025133.38M
20249.82M
202312.43M
202212.38M
202110.49M
2020729K
20195.11M
20185.79M
201711.67M
201620.19M
Debt ratios
-1012320182019202020212022202320242025
PALI Debt ratios by year
PeriodDebt ratios
20252.26
20240.15
20230.2
20220.21
20210.21
2020-0.02
20190.1
20180.15
Margins
-1500%-1000%-500%0%500%2015201620172018201920202023
PALI Margins by year
PeriodMargins
2023100%
2020-1108.92%
2019100%
2018100%
2017100%
2016100%
2015100%
Return on Capital
-400%-200%0%200%2016201720182019202020212022202320242025
PALI Return on Capital by year
PeriodReturn on Capital
2025-12.97%
2024-192.71%
2023-108.72%
2022-114.27%
2021-361.38%
2020145.4%
2019-178.97%
2018-81.39%
2017-183.98%
2016-186%
Shares Outstanding
020M40M60M2016201720182019202020212022202320242025
PALI Shares Outstanding by year
PeriodShares Outstanding
202555.67M
20245.82M
20235.82M
20221.8M
2021270.66K
2020832.44K
2019565.22K
2018273.24K
2017226.75K
2016167.12K
Book Value Per Share (USD)
-200204060802016201720182019202020212022202320242025
PALI Book Value Per Share (USD) by year
PeriodBook Value Per Share (USD)
20252.32
20241.29
20231.94
20226.93
202127.21
2020-8.53
20199.07
201822.14
201737.55
201667.8
Total Assets (USD)
050M100M150M2016201720182019202020212022202320242025
PALI Total Assets (USD) by year
PeriodTotal Assets (USD)
2025134.34M
202410.88M
202314.05M
202215.76M
202112.51M
20203.02M
20196.58M
20187.68M
201713.88M
201622.6M
Employee Count
0510152016201720182019202020212022202320242025
PALI Employee Count by year
PeriodEmployee Count
202514
20248
20239
202212
202113
20207
20195
20186
20176
201611
PE Ratio
510152025med 12.13Aug 22Sep 22Sep 22Sep 22Oct 22Oct 22Nov 22
PALI PE Ratio by year
PeriodPE Ratio
Nov 229.55
Nov 229.98
Oct 2211.07
Oct 2212.13
Oct 2211.07
Oct 2211.58
Sep 2211.54
Sep 2213.3
Sep 2216.32
Sep 2217.26
Sep 2217.22
Aug 2221.45
Aug 2220.99
Free Cash Flow Yield
-400%-300%-200%-100%0%med -89.51%Dec 24Apr 25Jul 25Oct 25Feb 26May 26Sep 26
PALI Free Cash Flow Yield by year
PeriodFree Cash Flow Yield
Sep 26-4.18%
Sep 26-4.12%
Aug 26-4.3%
Aug 26-4.1%
Aug 26-4.02%
Aug 26-2.8%
Jul 26-3.11%
Jul 26-3.03%
Jul 26-3%
Jul 26-3.02%
Jul 26-2.82%
Jun 26-3.13%
Jun 26-3.16%
Jun 26-3.46%
Jun 26-3.4%
May 26-2.79%
May 26-3.03%
May 26-3.23%
May 26-10.82%
May 26-9.79%
Apr 26-9.37%
Apr 26-8.12%
Apr 26-10.71%
Apr 26-10.31%
Mar 26-9.74%
Mar 26-10.31%
Mar 26-69.55%
Mar 26-82.77%
Feb 26-76.23%
Feb 26-84.33%
Feb 26-77.99%
Feb 26-82.27%
Jan 26-90.55%
Jan 26-70.64%
Jan 26-81.28%
Jan 26-67.8%
Jan 26-53.97%
Dec 25-62.75%
Dec 25-73.73%
Dec 25-69.55%
Dec 25-74.96%
Nov 25-63.94%
Nov 25-63.34%
Nov 25-63.05%
Nov 25-119.91%
Oct 25-97.32%
Oct 25-115.78%
Oct 25-115.78%
Oct 25-100.73%
Oct 25-125.91%
Sep 25-224.28%
Sep 25-335.7%
Sep 25-336.87%
Sep 25-321.55%
Aug 25-298.09%
Aug 25-267.18%
Aug 25-251.5%
Aug 25-299.42%
Aug 25-234.23%
Jul 25-203.94%
Jul 25-315.35%
Jul 25-314.17%
Jul 25-326.31%
Jun 25-337.96%
Jun 25-383.24%
Jun 25-369.59%
Jun 25-339.56%
May 25-318.83%
May 25-293.15%
May 25-344.46%
May 25-277.73%
May 25-264.48%
Apr 25-291.07%
Apr 25-291.12%
Apr 25-300.68%
Apr 25-293.27%
Mar 25-304.3%
Mar 25-303.67%
Mar 25-215.85%
Mar 25-254.57%
Feb 25-260.37%
Feb 25-228.85%
Feb 25-207.55%
Feb 25-172.68%
Jan 25-158.71%
Jan 25-142%
Jan 25-145.84%
Jan 25-113.01%
Jan 25-113.6%
Dec 24-129.25%
Dec 24-123.34%
Dec 24-121.95%
Dec 24-121.95%
Nov 24-87.74%
Nov 24-88.46%
Nov 24-85.65%
Nov 24-81.79%
Nov 24-75%
Oct 24-58.85%
Oct 24-53.41%
Price to Sales
050000010000001500000med 516.63Jan 21Apr 21Aug 21Aug 23Nov 23Mar 24Sep 26
PALI Price to Sales by year
PeriodPrice to Sales
Sep 26870.89
Sep 26883.58
Aug 26845.53
Aug 26887.8
Aug 26904.71
May 24156.16
May 24180.13
Apr 24140.8
Apr 24109.61
Apr 2495.88
Apr 24128.93
Mar 24139.4
Mar 24140.38
Mar 24135.38
Mar 24144.89
Mar 24153.15
Feb 24151.65
Feb 24161.4
Feb 24165.16
Feb 24202.19
Jan 24195.19
Jan 24200.94
Jan 24196.44
Jan 24198.94
Dec 23221.46
Dec 23224.47
Dec 23214.71
Dec 23234.22
Dec 23227.22
Nov 23219.71
Nov 23226.97
Nov 23198.94
Nov 23221
Oct 23207.94
Oct 23238.15
Oct 23212.29
Oct 23211.78
Sep 23223.56
Sep 23209.99
Sep 23235.08
Sep 23290.14
Sep 23254.29
Aug 23242.76
Aug 23234.31
Aug 23272.73
Aug 23528.28
Jul 23582.66
Jul 23551.58
Jul 23504.97
Jul 23453.18
Jun 23440.23
Jun 23450.59
Jun 23414.34
Jun 23414.34
Jun 23359.95
May 23349.6
May 23385.85
May 23411.75
Aug 21634250.7
Aug 21649233
Aug 21674203.5
Jul 21731635.65
Jul 21848997
Jul 21841505.85
Jul 21946381.95
Jul 21906429.15
Jun 211096204.95
Jun 211031281.65
Jun 211026287.55
Jun 21943884.9
May 21951376.05
May 21943884.9
May 21938890.8
May 21437470.67
Apr 21557646.87
Apr 21694654.57
Apr 21611120.39
Apr 21694654.57
Apr 21743016.21
Mar 21681464.5
Mar 21557399.57
Mar 21492822.95
Mar 21404454.88
Feb 21455435.94
Feb 21625375.07
Feb 21625375.07
Feb 21496221.84
Jan 21499619.98
Jan 21486025.18
Jan 21452037.05
Jan 21421448.56
Dec 20299092.36
Dec 20304054.74
Dec 20321184.38
Dec 20233835.97
Dec 20226154.48
Nov 20203926.51
Nov 20210724.28
Nov 20196448.95
Nov 20150330.9
EV/EBITDA
0200000400000600000800000med 392583.67Nov 16Dec 16Jan 17Mar 17Sep 22Oct 22Nov 22
PALI EV/EBITDA by year
PeriodEV/EBITDA
Nov 227.28
Nov 227.68
Oct 228.66
Oct 229.63
Oct 228.66
Oct 229.13
Sep 229.1
Sep 2210.7
Sep 2213.44
Sep 2214.29
Sep 2214.26
Aug 2218.1
Aug 2217.68
Mar 17720572.33
Mar 17642302.31
Mar 17529245.62
Feb 17479550.36
Feb 17458429.87
Feb 17393826.05
Feb 17375190.33
Jan 17391341.29
Jan 17474580.83
Jan 17524276.08
Jan 17497428.32
Dec 16441690.81
Dec 16508737.39
Dec 16437813.42
Dec 16381268.1
Dec 16432805.12
Nov 16449122.48
Nov 16471740.6
Nov 16452192.07
Price to Book
0246med 1.63Dec 24Apr 25Jul 25Oct 25Feb 26May 26Sep 26
PALI Price to Book by year
PeriodPrice to Book
Sep 263.58
Sep 263.63
Aug 263.47
Aug 263.65
Aug 263.72
Aug 263.47
Jul 263.13
Jul 263.21
Jul 263.24
Jul 263.23
Jul 263.46
Jun 263.11
Jun 263.08
Jun 262.82
Jun 262.86
May 263.49
May 263.21
May 263.01
May 260.77
May 260.86
Apr 260.89
Apr 261.03
Apr 260.78
Apr 260.81
Mar 260.86
Mar 260.81
Mar 264.51
Mar 263.79
Feb 264.12
Feb 263.72
Feb 264.03
Feb 263.82
Jan 263.47
Jan 264.44
Jan 263.86
Jan 264.63
Jan 265.82
Dec 255
Dec 254.26
Dec 254.51
Dec 254.19
Nov 254.91
Nov 254.96
Nov 254.98
Nov 253.08
Oct 253.79
Oct 253.19
Oct 253.19
Oct 253.66
Oct 252.93
Sep 251.64
Sep 251.1
Sep 251.09
Sep 251.15
Aug 251.24
Aug 251.38
Aug 251.47
Aug 250.71
Aug 250.91
Jul 251.04
Jul 250.67
Jul 250.68
Jul 250.65
Jun 250.63
Jun 250.56
Jun 250.58
Jun 250.63
May 250.67
May 250.73
May 250.62
May 250.59
May 250.62
Apr 250.56
Apr 250.56
Apr 250.54
Apr 250.55
Mar 250.53
Mar 250.63
Mar 250.88
Mar 250.75
Feb 250.73
Feb 250.83
Feb 250.92
Feb 251.1
Jan 251.2
Jan 251.34
Jan 251.3
Jan 251.68
Jan 251.67
Dec 241.47
Dec 241.54
Dec 241.56
Dec 241.56
Nov 242.17
Nov 242.15
Nov 242.22
Nov 241.49
Nov 241.62
Oct 242.06
Oct 242.27
Palisade Bio, Inc.
PALI
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News: PALI

Palisade Bio to Participate in Upcoming Investor Conferences

globenewswire.com · 3 Sep 2026

Palisade Bio to Participate in Upcoming Investor Conferences

Denver, CO, Sept. 03, 2026 (GLOBE NEWSWIRE) -- Palisade Bio, Inc. (Nasdaq: PALI) (“Palisade” or the “Company”), a clinical-stage biopharmaceutical company developing next-generation prodrugs for patients living with inflammatory and fibrotic diseases, today announced that members of management will participate in three healthcare investor conferences in September 2026.

Brokerages Set Palisade Bio, Inc. (NASDAQ:PALI) Price Target at $9.00

defenseworld.net · 17 Aug 2026

Brokerages Set Palisade Bio, Inc. (NASDAQ:PALI) Price Target at $9.00

Palisade Bio, Inc. (NASDAQ: PALI - Get Free Report) has received a consensus rating of "Buy" from the ten ratings firms that are covering the firm, Marketbeat Ratings reports. One research analyst has rated the stock with a sell recommendation, seven have assigned a buy recommendation and two have given a strong buy recommendation to the

Palisade Bio Reports Second Quarter 2026 Financial Results and Highlights Continued Advancement of PALI-2108 Into Phase 2 Development

globenewswire.com · 10 Aug 2026

Palisade Bio Reports Second Quarter 2026 Financial Results and Highlights Continued Advancement of PALI-2108 Into Phase 2 Development

Advancing a potentially best-in-class once-daily oral, locally-activated PDE4 inhibitor prodrug specifically engineered for the treatment of inflammatory bowel disease (IBD) Enrollment of first patient for Phase 2 ASCENTRA-UC trial of PALI-2108 expected in the second half of 2026; primary efficacy results expected in the second half of 2027 IND for Phase 2 ASCENTRA-CD trial of PALI-2108 for the treatment of Crohn's disease expected in the second half of 2026 Strong balance sheet expected to support execution through key Phase 2 clinical readouts Denver, CO, Aug.

Palisade Bio Draws Bullish Call, Lead IBD Drug Advances Toward Phase 2

benzinga.com · 23 Jul 2026

Palisade Bio Draws Bullish Call, Lead IBD Drug Advances Toward Phase 2

Oppenheimer on Thursday initiated coverage of Palisade Bio Inc. (NASDAQ:PALI) , saying the stock offers investors an attractive way to gain exposure to the fast-growing inflammatory bowel disease market.

Palisade Bio to Participate in the Leerink Partners Therapeutics Forum

globenewswire.com · 10 Jul 2026

Palisade Bio to Participate in the Leerink Partners Therapeutics Forum

Management to participate in investor meetings on July 14-15 in Boston Denver, CO, July 10, 2026 (GLOBE NEWSWIRE) -- Palisade Bio, Inc. (Nasdaq: PALI) ("Palisade" or the "Company"), a clinical-stage biopharmaceutical company developing next-generation oral PDE4 inhibitor prodrugs for inflammatory bowel disease, today announced that JD Finley, Chief Executive Officer, and Dr.

Palisade Bio to Participate in the Leerink Partners Therapeutics Forum

globenewswire.com · 10 Jul 2026

Palisade Bio to Participate in the Leerink Partners Therapeutics Forum

Management to participate in investor meetings on July 14-15 in Boston Denver, CO, July 10, 2026 (GLOBE NEWSWIRE) -- Palisade Bio, Inc. (Nasdaq: PALI) (“Palisade” or the “Company”), a clinical-stage biopharmaceutical company developing next-generation oral PDE4 inhibitor prodrugs for inflammatory bowel disease, today announced that JD Finley, Chief Executive Officer, and Dr. Mitchell Jones, President & Chief Medical Officer, will participate in the Leerink Partners Therapeutics Forum, taking place July 14-15, 2026, in Boston, Massachusetts. Management will participate in one-on-one meetings with institutional investors throughout the conference to discuss the Company's clinical development strategy, recent progress advancing PALI-2108 and upcoming milestones across its inflammatory bowel disease programs.

Palisade Bio: A Unique MoA Targeting The UC And Crohn's Disease Markets

seekingalpha.com · 10 Jul 2026

Palisade Bio: A Unique MoA Targeting The UC And Crohn's Disease Markets

Palisade Bio offers a speculative early-stage opportunity, advancing PALI-2108, a gut-restricted PDE4 inhibitor for UC and Crohn's disease. PALI-2108's Phase 1 trials showed favorable safety, target engagement, and early clinical activity, supporting a differentiated mechanism of action. PALI's $132.6 million cash runway funds operations through key Phase 2 efficacy readouts in 2027–2028, reducing near-term dilution risk.

Palisade Bio Receives FDA Clearance of IND for PALI-2108 and Plans to Initiate Global Phase 2 ASCENTRA-UC Study in Ulcerative Colitis

globenewswire.com · 29 Jun 2026

Palisade Bio Receives FDA Clearance of IND for PALI-2108 and Plans to Initiate Global Phase 2 ASCENTRA-UC Study in Ulcerative Colitis

ASCENTRA-UC expected to enroll up to 204 patients with moderately to severely active ulcerative colitis across North America and Europe

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