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Milestone Pharmaceuticals Inc.

$0.98 -$1.07 (-52.19%)
NASDAQ · 11 Sep 2026 20:00 UTC
Previous Close
$1.05
Day Range
$0.98$1.06
Year Range
$0.98$3.06
Market Cap
122.02M
AVG Volume
1.48M
Trailing/Forward PE
-1.42/-
PEG ratio
1.4
Dividend Yield
-
Next Earnings Date
2026-11-11
Primary Exchange
NASDAQUS
Revenue (USD)
05M10M15M20182019202020212022202320242025
MIST Revenue (USD) by year
PeriodRevenue (USD)
20251.55M
20240
20231M
20225M
202115M
20200
20190
20180
Net Income (USD)
-80M-60M-40M-20M020182019202020212022202320242025
MIST Net Income (USD) by year
PeriodNet Income (USD)
2025-63.06M
2024-41.52M
2023-59.69M
2022-58.39M
2021-42.85M
2020-49.97M
2019-55.23M
2018-23.19M
Operating Income (USD)
-80M-60M-40M-20M020182019202020212022202320242025
MIST Operating Income (USD) by year
PeriodOperating Income (USD)
2025-62.21M
2024-42.1M
2023-61.1M
2022-59.64M
2021-43.15M
2020-50.71M
2019-57.88M
2018-23.82M
EBITDA (USD)
-60M-40M-20M020182019202020212022202320242025
MIST EBITDA (USD) by year
PeriodEBITDA (USD)
2025-59.18M
2024-37.83M
2023-57.04M
2022-58.3M
2021-42.65M
2020-50.45M
2019-57.84M
2018-23.81M
Cash Flows (USD)
-60M-40M-20M020182019202020212022202320242025
MIST Cash Flows (USD) by year
PeriodCash Flows (USD)
2025-49.14M
2024-28.88M
2023-46.54M
2022-52.74M
2021-33.22M
2020-50.73M
2019-51.56M
2018-21.05M
EPS (USD)
-3-2-1020182019202020212022202320242025
MIST EPS (USD) by year
PeriodEPS (USD)
2025-0.79
2024-0.69
2023-1.48
2022-0.62
2021-1.02
2020-1.89
2019-2.28
2018-0.98
Expenses (USD)
020M40M60M80MR&DSG&ACapex20182019202020212022202320242025
MIST Expenses (USD) by year
PeriodExpenses (USD)
202563.76M
202442.13M
202362.21M
202264.56M
202158.15M
202050.98M
201958.29M
201823.83M
Cash & Debt (USD)
050M100M150MCashLong Term DebtShort Term Debt20182019202020212022202320242025
MIST Cash & Debt (USD) by year
PeriodCash & Debt (USD)
2025105.96M
202469.69M
202366M
202264.58M
2021114.14M
2020142.31M
2019119.82M
201885.98M
Debt ratios
00.20.40.60.820212022202320242025
MIST Debt ratios by year
PeriodDebt ratios
20250.22
20240.08
20230.07
20220.3
20210.65
Margins
0%25%50%75%100%2021202220232025
MIST Margins by year
PeriodMargins
202598.38%
2023100%
2022100%
202133.17%
Return on Capital
-400%-300%-200%-100%0%100%20182019202020212022202320242025
MIST Return on Capital by year
PeriodReturn on Capital
2025-150.97%
2024-315.81%
2023-355.88%
2022-88%
2021-38.06%
2020-34.91%
2019-48.06%
201842%
Shares Outstanding
025M50M75M100M20182019202020212022202320242025
MIST Shares Outstanding by year
PeriodShares Outstanding
202583.88M
202462.21M
202333.48M
202242.78M
202142.18M
202029.77M
201924.51M
201823.65M
Book Value Per Share (USD)
-4-2024620182019202020212022202320242025
MIST Book Value Per Share (USD) by year
PeriodBook Value Per Share (USD)
20250.5
20240.21
20230.5
20221.55
20212.67
20204.81
20194.69
2018-2.33
Total Assets (USD)
050M100M150M20182019202020212022202320242025
MIST Total Assets (USD) by year
PeriodTotal Assets (USD)
2025113.56M
202475.5M
202375.23M
202274.48M
2021119.85M
2020149.97M
2019123.43M
201888.08M
Employee Count
02040602019202020212022202320242025
MIST Employee Count by year
PeriodEmployee Count
202538
202433
202347
202239
202129
202028
201930
Free Cash Flow Yield
-80%-60%-40%-20%med -31.71%Dec 24Apr 25Jul 25Oct 25Feb 26May 26Sep 26
MIST Free Cash Flow Yield by year
PeriodFree Cash Flow Yield
Sep 26-45.03%
Sep 26-36.78%
Aug 26-38.05%
Aug 26-41.64%
Aug 26-40.13%
Aug 26-32.23%
Jul 26-35.43%
Jul 26-33.9%
Jul 26-33.05%
Jul 26-30.72%
Jul 26-29.79%
Jun 26-31.71%
Jun 26-30.25%
Jun 26-30.96%
Jun 26-31.97%
May 26-27.69%
May 26-27.89%
May 26-26.04%
May 26-30.51%
May 26-31.33%
Apr 26-30.99%
Apr 26-27.9%
Apr 26-29%
Apr 26-42.45%
Mar 26-56.33%
Mar 26-43.07%
Mar 26-38.3%
Mar 26-41.21%
Feb 26-38.07%
Feb 26-38.3%
Feb 26-38.3%
Feb 26-36.99%
Jan 26-34.09%
Jan 26-32.88%
Jan 26-31.76%
Jan 26-31.91%
Jan 26-31.76%
Dec 25-31.3%
Dec 25-30.28%
Dec 25-27.02%
Dec 25-24.29%
Nov 25-24.2%
Nov 25-27.13%
Nov 25-32.55%
Nov 25-35.61%
Oct 25-31.72%
Oct 25-32.39%
Oct 25-31.39%
Oct 25-30.6%
Oct 25-28.86%
Sep 25-30.45%
Sep 25-31.72%
Sep 25-31.07%
Sep 25-33.83%
Aug 25-33.09%
Aug 25-35.82%
Aug 25-35.82%
Aug 25-34.1%
Aug 25-35.77%
Jul 25-32.37%
Jul 25-32.37%
Jul 25-32.79%
Jul 25-26.37%
Jun 25-27.5%
Jun 25-30.27%
Jun 25-31%
Jun 25-29.57%
May 25-31.57%
May 25-33.21%
May 25-41.93%
May 25-41.82%
May 25-35.44%
Apr 25-36.27%
Apr 25-52.23%
Apr 25-60.19%
Apr 25-66.73%
Mar 25-52.76%
Mar 25-24.43%
Mar 25-21.39%
Mar 25-26.15%
Feb 25-29.51%
Feb 25-23.58%
Feb 25-21.19%
Feb 25-22.38%
Jan 25-24.42%
Jan 25-23.47%
Jan 25-24.3%
Jan 25-23.13%
Jan 25-21.87%
Dec 24-22.38%
Dec 24-26.73%
Dec 24-26.73%
Dec 24-25.86%
Nov 24-24.18%
Nov 24-26.15%
Nov 24-28.3%
Nov 24-28.24%
Nov 24-38.83%
Oct 24-38.83%
Oct 24-37.53%
Price to Sales
050100150med 30.71Feb 23Jun 23Sep 23Dec 23Apr 24May 26Sep 26
MIST Price to Sales by year
PeriodPrice to Sales
Sep 2658.02
Sep 2671.03
Aug 2668.67
Aug 2662.75
Aug 2665.11
Aug 2689.1
Jul 2681.06
Jul 2684.72
Jul 2686.91
Jul 2693.48
Jul 2696.4
Jun 2690.56
Jun 2694.94
Jun 2692.75
Jun 2689.83
May 26103.7
May 26102.97
May 26110.28
May 26104.18
May 26101.46
Apr 26102.55
Apr 26113.94
Apr 26109.6
Apr 2674.88
Mar 2656.43
Mar 2673.79
May 2456.92
May 2456.59
Apr 2414.71
Apr 2415.66
Apr 2416.52
Apr 2417.19
Mar 2417.09
Mar 2416.62
Mar 2413.85
Mar 2414.42
Mar 2415.37
Feb 2416.23
Feb 2414.61
Feb 2415.28
Feb 2415.57
Jan 2414.71
Jan 2413.37
Jan 2414.8
Jan 2416.43
Dec 2315.95
Dec 2327.5
Dec 2324.92
Dec 2328.17
Dec 2330.27
Nov 2326.36
Nov 2321.01
Nov 2320.82
Nov 2320.11
Oct 2316.32
Oct 2319.39
Oct 2320.75
Oct 2321.47
Sep 2322.18
Sep 2321.47
Sep 2322.54
Sep 2320.75
Sep 2319.32
Aug 2320.4
Aug 2321.75
Aug 2322.69
Aug 2321.64
Jul 2322.5
Jul 2323.43
Jul 2325.14
Jul 2323.5
Jun 2320.36
Jun 2322.5
Jun 2325
Jun 2328.21
Jun 2326.85
May 2328.43
May 2330.71
May 2331.43
May 2330.72
Apr 2331.06
Apr 2334.4
Apr 2330.72
Apr 2333.28
Mar 2333.71
Mar 2395.18
Mar 2393.48
Mar 2390.65
Mar 2390.37
Feb 2388.95
Feb 23104.81
Feb 23109.63
Feb 23116.43
Jan 2399.15
Jan 23107.36
Jan 23111.33
Jan 23109.91
Dec 22112.18
Dec 22107.08
Dec 22103.4
Price to Book
02.557.51012.5med 4.61Jun 24Oct 24Jan 25May 25Feb 26May 26Sep 26
MIST Price to Book by year
PeriodPrice to Book
Sep 267.46
Sep 269.14
Aug 268.83
Aug 268.07
Aug 268.37
Aug 264.41
Jul 264.01
Jul 264.19
Jul 264.3
Jul 264.63
Jul 264.77
Jun 264.48
Jun 264.7
Jun 264.59
Jun 264.45
May 265.13
May 265.1
May 265.46
May 263.86
May 263.76
Apr 263.8
Apr 264.22
Apr 264.06
Apr 262.77
Mar 262.09
Mar 262.73
Mar 265.5
Mar 265.12
Feb 265.54
Feb 265.5
Feb 265.5
Feb 265.7
Jan 266.18
Jan 266.41
Jan 266.64
Jan 266.61
Jan 266.64
Dec 256.73
Dec 256.96
Dec 257.8
Dec 258.68
Nov 258.71
Nov 257.77
Nov 256.48
May 255.25
May 256.2
Apr 256.06
Apr 254.21
Apr 253.65
Apr 253.29
Mar 254.16
Mar 258.99
Mar 2510.27
Mar 255.07
Feb 254.49
Feb 255.62
Feb 256.26
Feb 255.93
Jan 255.43
Jan 255.65
Jan 255.46
Jan 255.73
Jan 256.06
Dec 245.93
Dec 244.96
Dec 244.96
Dec 245.13
Nov 245.49
Nov 245.07
Nov 244.69
Nov 244.1
Nov 242.98
Oct 242.98
Oct 243.08
Oct 243
Oct 243.1
Sep 243.17
Sep 243.21
Sep 243.15
Sep 243.02
Aug 242.94
Aug 243.04
Aug 242.77
Aug 242.92
Aug 241.68
Jul 241.9
Jul 241.86
Jul 241.96
Jul 241.67
Jun 241.66
Jun 241.73
Jun 241.77
Jun 241.83
May 241.88
May 242.15
May 242.19
May 243.39
May 243.37
Apr 242.32
Apr 242.47
Milestone Pharmaceuticals Inc.
MIST
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News: MIST

Milestone Pharmaceuticals Announces NMPA Approval of Etripamil Nasal Spray for PSVT in China, Marking First Regulatory Approval of Etripamil Outside of the United States

globenewswire.com · 3 Sep 2026

Milestone Pharmaceuticals Announces NMPA Approval of Etripamil Nasal Spray for PSVT in China, Marking First Regulatory Approval of Etripamil Outside of the United States

Everest Medicines to Lead Commercialization in Greater China, Bringing Novel Innovation to Estimated 3-6 Million Chinese Patients with PSVT

Milestone Pharmaceuticals to Present at Upcoming Investor Conferences

globenewswire.com · 2 Sep 2026

Milestone Pharmaceuticals to Present at Upcoming Investor Conferences

MONTREAL and CHARLOTTE, N.C., Sept. 02, 2026 (GLOBE NEWSWIRE) -- Milestone® Pharmaceuticals Inc. (Nasdaq: MIST), a biopharmaceutical company focused on the development and commercialization of innovative cardiovascular medicines, today announced that management will present at, and participate in, the following upcoming investor conferences.

Milestone Pharmaceuticals Announces Data Presented at ESC Congress 2026 on the Impact of Paroxysmal Supraventricular Tachycardia (PSVT) on Patients' Daily Lives and Quality of Life Between Episodes

globenewswire.com · 27 Aug 2026

Milestone Pharmaceuticals Announces Data Presented at ESC Congress 2026 on the Impact of Paroxysmal Supraventricular Tachycardia (PSVT) on Patients' Daily Lives and Quality of Life Between Episodes

MONTREAL and CHARLOTTE, N.C., Aug. 27, 2026 (GLOBE NEWSWIRE) -- Milestone® Pharmaceuticals Inc. (Nasdaq: MIST), a biopharmaceutical company focused on the development and commercialization of innovative cardiovascular medicines, today announced findings from a longitudinal study describing how paroxysmal supraventricular tachycardia (PSVT) affects patients' daily lives and quality of life in the periods between episodes.

Milestone Pharmaceuticals Initiates Pivotal Phase 3 Trial of Etripamil Nasal Spray for Self-Administered Treatment of Atrial Fibrillation with Rapid Ventricular Rate (AFib-RVR)

globenewswire.com · 21 Aug 2026

Milestone Pharmaceuticals Initiates Pivotal Phase 3 Trial of Etripamil Nasal Spray for Self-Administered Treatment of Atrial Fibrillation with Rapid Ventricular Rate (AFib-RVR)

ReVeRA-301 Trial is Evaluating the Same 70 mg Repeat-Dose Regimen that is FDA Approved for Paroxysmal Supraventricular Tachycardia (PSVT)

Milestone Pharmaceuticals: Reiterating Sell As The Losses Compound

seekingalpha.com · 18 Aug 2026

Milestone Pharmaceuticals: Reiterating Sell As The Losses Compound

Milestone Pharmaceuticals remains a 'Sell' due to weak CARDAMYST differentiation and poor commercial uptake versus low-cost generics. MIST's Q2 revenue was just $559K on over 1,200 scripts, reflecting heavy discounting and minimal payer coverage, with only ~20% of the PSVT market covered. Financial health is deteriorating: $170M cash, $39M 1H burn, liabilities doubled to $163M, and equity fell to $18M amid high SG&A and compounding royalty debt.

Milestone Pharmaceuticals Inc. (MIST) Q2 2026 Earnings Call Transcript

seekingalpha.com · 12 Aug 2026

Milestone Pharmaceuticals Inc. (MIST) Q2 2026 Earnings Call Transcript

Milestone Pharmaceuticals Inc. (MIST) Q2 2026 Earnings Call Transcript

Milestone Pharmaceuticals Q2 Earnings Call Highlights

marketbeat.com · 12 Aug 2026

Milestone Pharmaceuticals Q2 Earnings Call Highlights

Milestone Pharmaceuticals NASDAQ: MIST reported early commercial traction for CARDAMYST following its mid-February launch, while advancing a pivotal Phase III study of etripamil in atrial fibrillation with rapid ventricular rate, or AFib-RVR.

Milestone Pharmaceuticals (MIST) Reports Q2 Loss, Lags Revenue Estimates

zacks.com · 12 Aug 2026

Milestone Pharmaceuticals (MIST) Reports Q2 Loss, Lags Revenue Estimates

Milestone Pharmaceuticals (MIST) came out with a quarterly loss of $0.21 per share versus the Zacks Consensus Estimate of a loss of $0.18. This compares to a loss of $0.2 per share a year ago.

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