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Seres Therapeutics, Inc.

$5.01 -$10.14 (-66.93%)
NASDAQ · 11 Sep 2026 20:00 UTC
Previous Close
$5.1
Day Range
$5$5.29
Year Range
$4.32$29.98
Market Cap
48.52M
AVG Volume
78K
Trailing/Forward PE
-2.07/-
PEG ratio
-0.05
Dividend Yield
-
Next Earnings Date
2026-11-04
Primary Exchange
NASDAQUS
Revenue (USD)
050M100M150M2016201720182019202020212022202320242025
MCRB Revenue (USD) by year
PeriodRevenue (USD)
2025789K
20240
2023126.02M
20227.13M
2021144.93M
202033.22M
201934.51M
201828.27M
201732.1M
201621.77M
Net Income (USD)
-300M-200M-100M0100M2016201720182019202020212022202320242025
MCRB Net Income (USD) by year
PeriodNet Income (USD)
20255.7M
2024136K
2023-113.72M
2022-250.16M
2021-65.58M
2020-89.13M
2019-70.28M
2018-98.94M
2017-89.38M
2016-91.58M
Operating Income (USD)
-300M-200M-100M02016201720182019202020212022202320242025
MCRB Operating Income (USD) by year
PeriodOperating Income (USD)
2025-93.97M
2024-121.31M
2023-105.16M
2022-246.49M
2021-64.49M
2020-88.13M
2019-71.88M
2018-100.28M
2017-91.39M
2016-92.82M
EBITDA (USD)
-300M-200M-100M0100M2016201720182019202020212022202320242025
MCRB EBITDA (USD) by year
PeriodEBITDA (USD)
202511.03M
2024-119.69M
2023-91.48M
2022-237.51M
2021-57.28M
2020-80.03M
2019-63.09M
2018-92.42M
2017-84.14M
2016-88.22M
Cash Flows (USD)
-300M-200M-100M0100M2016201720182019202020212022202320242025
MCRB Cash Flows (USD) by year
PeriodCash Flows (USD)
2025865K
2024-148.99M
2023-125.33M
2022-238.64M
2021-2.88M
2020-94.2M
2019-77.95M
2018-64.79M
2017-80.2M
201622.43M
EPS (USD)
-60-40-200202016201720182019202020212022202320242025
MCRB EPS (USD) by year
PeriodEPS (USD)
20250.66
2024-19.23
2023-17.98
2022-47.1
2021-14.81
2020-22.51
2019-26.67
2018-48.56
2017-44.07
2016-1.66
Expenses (USD)
0100M200M300MR&DSG&ACapex2016201720182019202020212022202320242025
MCRB Expenses (USD) by year
PeriodExpenses (USD)
202588.47M
2024116.76M
2023237.92M
2022262.44M
2021220.72M
2020121.94M
2019105.89M
2018130.49M
2017128.17M
2016136.08M
Cash & Debt (USD)
0100M200M300MCashLong Term DebtShort Term Debt2016201720182019202020212022202320242025
MCRB Cash & Debt (USD) by year
PeriodCash & Debt (USD)
202545.77M
202430.79M
2023127.97M
2022181.34M
2021290.71M
2020253.62M
201994.82M
201885.82M
2017149.98M
2016193.24M
Debt ratios
-0.2500.250.50.75120182019202020212022202320242025
MCRB Debt ratios by year
PeriodDebt ratios
2025-0.09
2024-0.12
2023-0.15
20220.04
20210.82
20200.67
20190.15
20180.25
Margins
-3000%-2000%-1000%0%1000%201620172018201920202021202220232025
MCRB Margins by year
PeriodMargins
2025-423.83%
202324.21%
2022-2325.93%
20212.09%
202025.13%
2019-132.26%
2018-239.46%
2017-178.68%
2016-276.7%
Return on Capital
-3000%-2000%-1000%0%1000%2016201720182019202020212022202320242025
MCRB Return on Capital by year
PeriodReturn on Capital
202512.88%
20240.99%
2023253.53%
2022-2319.92%
2021-49.87%
2020-51%
2019145.43%
2018205.94%
2017-147.25%
2016-69.05%
Shares Outstanding
02.5M5M7.5M10M2016201720182019202020212022202320242025
MCRB Shares Outstanding by year
PeriodShares Outstanding
20258.86M
20248.65M
20236.46M
20226.26M
20214.59M
20204.57M
20193.51M
20182.05M
20172.03M
20160
Book Value Per Share (USD)
-40-2002040201720182019202020212022202320242025
MCRB Book Value Per Share (USD) by year
PeriodBook Value Per Share (USD)
20254.99
20241.59
2023-6.94
20221.72
202128.62
202038.21
2019-13.78
2018-23.47
201729.92
Total Assets (USD)
0100M200M300M400M2016201720182019202020212022202320242025
MCRB Total Assets (USD) by year
PeriodTotal Assets (USD)
2025138.19M
2024139.81M
2023358.6M
2022348.78M
2021354.86M
2020342.94M
2019132.44M
2018120.47M
2017189.52M
2016272.65M
Employee Count
02004006002016201720182019202020212022202320242025
MCRB Employee Count by year
PeriodEmployee Count
202566
2024103
2023160
2022431
2021333
2020155
2019108
2018100
2017138
2016127
PE Ratio
02505007501000med 13.32Apr 25Jun 25Aug 25Oct 25Dec 25Feb 26May 26
MCRB PE Ratio by year
PeriodPE Ratio
May 2611.84
Apr 2612.6
Apr 2613.83
Apr 2612.94
Apr 2614.42
Mar 2614
Mar 2613.22
Mar 2613.42
Mar 2614.83
Feb 2614.19
Feb 2613.88
Feb 2613.75
Feb 2622.67
Jan 2624.23
Jan 2624.44
Jan 2625.92
Jan 2625.41
Jan 2624.6
Dec 2523.79
Dec 2524.32
Dec 2527.51
Dec 2527.05
Nov 2529.21
Nov 2528.76
Nov 2527.05
Nov 2522.77
Oct 251.64
Oct 251.82
Oct 251.92
Oct 251.94
Oct 252.09
Sep 251.93
Sep 251.77
Sep 251.62
Sep 251.97
Aug 251.93
Aug 251.98
Aug 251.7
Aug 251.45
Aug 251.67
Jul 251.73
Jul 251.68
Jul 251.5
Jul 251.42
Jun 251.09
Jun 250.88
Jun 250.89
Jun 250.98
May 250.84
May 250.92
May 250.89
May 250.84
May 25612.53
Apr 25641.15
Apr 25470.68
Apr 25751.19
Apr 25814.16
Mar 25917.2
Mar 25905.11
Mar 25877.76
Free Cash Flow Yield
-300%-200%-100%0%100%med -71.83%Dec 24Apr 25Jul 25Oct 25Feb 26May 26Sep 26
MCRB Free Cash Flow Yield by year
PeriodFree Cash Flow Yield
Sep 26-106.16%
Sep 26-92.98%
Aug 26-104.08%
Aug 26-116.63%
Aug 26-117.15%
Aug 26-109.21%
Jul 26-91.55%
Jul 26-88.97%
Jul 26-82.96%
Jul 26-72.37%
Jul 26-57.13%
Jun 26-62.45%
Jun 26-66.89%
Jun 26-77.57%
Jun 26-66.69%
May 26-60.41%
May 26-55.83%
May 26-57.88%
May 26-57.42%
May 261.28%
Apr 261.21%
Apr 261.1%
Apr 261.17%
Apr 261.05%
Mar 261.08%
Mar 261.15%
Mar 261.13%
Mar 26-29.22%
Feb 26-30.53%
Feb 26-31.2%
Feb 26-31.5%
Feb 26-19.11%
Jan 26-17.88%
Jan 26-17.73%
Jan 26-16.72%
Jan 26-17.05%
Jan 26-17.61%
Dec 25-18.21%
Dec 25-17.81%
Dec 25-15.75%
Dec 25-16.01%
Nov 25-14.83%
Nov 25-15.06%
Nov 25-16.01%
Nov 25-19.03%
Oct 25-42.89%
Oct 25-38.68%
Oct 25-36.51%
Oct 25-36.11%
Oct 25-33.54%
Sep 25-36.48%
Sep 25-39.57%
Sep 25-43.4%
Sep 25-35.67%
Aug 25-36.46%
Aug 25-35.52%
Aug 25-41.37%
Aug 25-48.59%
Aug 25-71.3%
Jul 25-68.65%
Jul 25-70.9%
Jul 25-79.36%
Jul 25-84.04%
Jun 25-109.62%
Jun 25-134.8%
Jun 25-133%
Jun 25-121.2%
May 25-141.49%
May 25-130.05%
May 25-133.71%
May 25-141.29%
May 25-178.85%
Apr 25-170.87%
Apr 25-232.75%
Apr 25-145.84%
Apr 25-134.56%
Mar 25-119.44%
Mar 25-121.04%
Mar 25-124.81%
Mar 25-135.55%
Feb 25-136.62%
Feb 25-129.14%
Feb 25-124.64%
Feb 25-132.69%
Jan 25-122.8%
Jan 25-120.38%
Jan 25-135.2%
Jan 25-122.87%
Jan 25-114.59%
Dec 24-116.98%
Dec 24-113.34%
Dec 24-118.11%
Dec 24-126%
Nov 24-105.88%
Nov 24-135.02%
Nov 24-188.83%
Nov 24-170.44%
Nov 24-148.25%
Oct 24-172.85%
Oct 24-143.87%
Price to Sales
0100020003000med 100.44Apr 24Aug 24Nov 24Mar 25Feb 26May 26Sep 26
MCRB Price to Sales by year
PeriodPrice to Sales
Sep 2625.66
Sep 2629.3
Aug 2626.17
Aug 2623.36
Aug 2623.25
Aug 2624.94
Jul 2640.35
Jul 2641.52
Jul 2644.53
Jul 2651.05
Jul 2664.66
Jun 2659.15
Jun 2655.22
Jun 2647.62
Jun 2655.39
May 2661.15
May 2666.17
May 2663.83
May 2664.33
May 2685.45
Apr 2690.95
Apr 2699.82
Apr 2693.42
Apr 26104.08
Mar 26101.05
Mar 2695.44
Mar 2696.9
Mar 26227.83
Feb 26218.09
Feb 26213.35
Feb 26211.36
Feb 26348.35
Jan 26372.31
Jan 26375.55
Jan 26398.26
Jan 26390.52
Jan 26378.05
Dec 25365.57
Dec 25373.8
Dec 25422.71
Dec 25415.73
Nov 25448.91
Nov 25441.93
Nov 25415.73
Nov 25349.85
Mar 251825.82
Feb 251811.51
Feb 251916.45
Feb 251985.62
Feb 251865.17
Jan 252015.43
Jan 252055.98
Jan 251830.59
Jan 252014.24
Jan 252159.73
Dec 242115.61
Dec 242183.59
Dec 242095.34
Dec 241964.15
Nov 242337.43
Nov 241832.97
Nov 241310.63
Nov 241692.68
Nov 241945.99
Oct 241669
Oct 242005.17
Oct 241909.29
Oct 242008.72
Sep 242175.62
Sep 242675.14
Sep 242365.01
Sep 242258.48
Aug 241895.09
Aug 242060.81
Aug 242083.3
Aug 241.05
Aug 241.44
Jul 241.52
Jul 241.42
Jul 241.24
Jul 240.94
Jun 240.84
Jun 240.9
Jun 240.82
Jun 240.71
May 241.15
May 241.06
May 241.06
May 241.18
May 241.19
Apr 240.85
Apr 240.57
Apr 240.67
Apr 240.78
Mar 240.79
Mar 240.79
Mar 240.81
Mar 241
Mar 241.24
Feb 241.07
EV/EBITDA
510152025med 16.56Nov 25Dec 25Jan 26Feb 26Mar 26Apr 26May 26
MCRB EV/EBITDA by year
PeriodEV/EBITDA
May 269.49
Apr 269.88
Apr 2610.52
Apr 2610.06
Apr 2610.82
Mar 2610.61
Mar 2610.2
Mar 2610.31
Mar 2612.16
Feb 2611.8
Feb 2611.63
Feb 2611.56
Feb 2616.53
Jan 2617.4
Jan 2617.52
Jan 2618.34
Jan 2618.06
Jan 2617.61
Dec 2517.15
Dec 2517.45
Dec 2519.23
Dec 2518.97
Nov 2520.18
Nov 2519.92
Nov 2518.97
Nov 2516.58
Price/Operating Cashflow
0255075100125med 18.63Nov 16Jan 17Nov 21Jan 22Mar 22Apr 22May 26
MCRB Price/Operating Cashflow by year
PeriodPrice/Operating Cashflow
May 2660.36
Apr 2664.24
Apr 2670.51
Apr 2665.99
Apr 2673.52
Mar 2671.38
Mar 2667.41
Mar 2668.44
Apr 2264.99
Apr 2271.99
Apr 2283.54
Apr 2293.29
Apr 22100.85
Mar 2298.51
Mar 22103.46
Mar 2297.82
Mar 2286.56
Feb 2218.63
Feb 2218.18
Feb 2218.57
Feb 2216.67
Jan 2217.75
Jan 2216.96
Jan 2218.16
Jan 2219.31
Dec 2118.82
Dec 2120.71
Dec 2118.77
Dec 2121.62
Dec 2124.12
Nov 2121.12
Nov 2120.69
Nov 2117.44
Mar 176.99
Mar 177.2
Feb 176.81
Feb 177.17
Feb 177.11
Feb 177.32
Jan 177.44
Jan 177.61
Jan 178.2
Jan 178.33
Dec 167.42
Dec 167.62
Dec 167.32
Dec 167.34
Dec 167.74
Nov 168.17
Nov 168.72
Nov 169.24
Price to Book
02.557.51012.5med 3.03Dec 24Apr 25Jul 25Oct 25Feb 26May 26Sep 26
MCRB Price to Book by year
PeriodPrice to Book
Sep 261.4
Sep 261.6
Aug 261.43
Aug 261.27
Aug 261.27
Aug 261.36
Jul 261.75
Jul 261.8
Jul 261.93
Jul 262.21
Jul 262.8
Jun 262.56
Jun 262.39
Jun 262.06
Jun 262.4
May 262.65
May 262.86
May 262.76
May 262.78
May 261.52
Apr 261.62
Apr 261.78
Apr 261.67
Apr 261.86
Mar 261.8
Mar 261.7
Mar 261.73
Mar 261.83
Feb 261.75
Feb 261.71
Feb 261.7
Feb 262.8
Jan 262.99
Jan 263.02
Jan 263.2
Jan 263.14
Jan 263.04
Dec 252.94
Dec 253
Dec 253.4
Dec 253.34
Nov 253.61
Nov 253.55
Nov 253.34
Nov 252.81
Oct 254.27
Oct 254.74
Oct 255.02
Oct 255.07
Oct 255.46
Sep 255.02
Sep 254.63
Sep 254.22
Sep 255.14
Aug 255.03
Aug 255.16
Aug 254.43
Aug 253.77
Aug 252.41
Jul 252.51
Jul 252.43
Jul 252.17
Jul 252.05
Jun 251.57
Jun 251.28
Jun 251.29
Jun 251.42
May 251.22
May 251.32
May 251.29
May 251.22
May 256.04
Apr 256.33
Apr 254.64
Apr 257.41
Apr 258.03
Mar 259.05
Mar 258.93
Mar 258.66
Mar 254.89
Feb 254.85
Feb 255.13
Feb 255.31
Feb 254.99
Jan 255.39
Jan 255.5
Jan 254.9
Jan 255.39
Jan 255.78
Dec 245.66
Dec 245.84
Dec 245.61
Dec 245.26
Nov 246.25
Nov 244.9
Nov 243.51
Oct 237.79
Oct 238.02
Oct 238.47
Oct 2311.04
Seres Therapeutics, Inc.
MCRB
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News: MCRB

Seres Therapeutics Reports Inducement Grants Under Nasdaq Listing Rule 5635(c)(4)

globenewswire.com · 8 Sep 2026

Seres Therapeutics Reports Inducement Grants Under Nasdaq Listing Rule 5635(c)(4)

CAMBRIDGE, Mass., Sept. 08, 2026 (GLOBE NEWSWIRE) -- Seres Therapeutics, Inc. (Nasdaq: MCRB) (“Seres” or the “Company”), a leading live biotherapeutics company, today announced that on September 4, 2026, the Compensation and Talent Committee of Seres' board of directors granted inducement equity grants consisting of stock options to purchase an aggregate of 4,200 shares of its common stock to two new employees. These stock options are subject to the terms of the Seres Therapeutics, Inc. 2022 Employment Inducement Award Plan (the “Inducement Plan”). The Inducement Plan is used exclusively for the grant of equity awards to individuals as an inducement material to their entering into employment with Seres pursuant to Nasdaq Listing Rule 5635(c)(4). The Inducement Plan was adopted by Seres' board of directors in December 2022. The stock options have an exercise price of $5.72 per share. Each option will vest as to 25% of the total number of shares subject to the option on the first anniversary of the individual's date of hire and as to 6.25% of the total number of shares subject to the option upon completion of each three full months of service to the Company thereafter.

Seres Therapeutics to Participate in H.C. Wainwright 28th Annual Global Investment Conference

globenewswire.com · 1 Sep 2026

Seres Therapeutics to Participate in H.C. Wainwright 28th Annual Global Investment Conference

CAMBRIDGE, Mass., Sept. 01, 2026 (GLOBE NEWSWIRE) -- Seres Therapeutics, Inc. (Nasdaq: MCRB), a leading live biotherapeutics company, today announced that management will attend the upcoming H.C. Wainwright 28th Annual Global Investment Conference taking place in New York, NY and will present a company overview at 2 p.m. ET on September 15, 2026.

Seres Therapeutics Reports Second Quarter 2026 Financial Results and Provides Business Updates, Including Further Action to Reduce Ongoing Facilities Costs

globenewswire.com · 5 Aug 2026

Seres Therapeutics Reports Second Quarter 2026 Financial Results and Provides Business Updates, Including Further Action to Reduce Ongoing Facilities Costs

Recently announced 80% of SER-155 recipients achieved immunosuppressive-free clinical response at day 15 for immune checkpoint inhibitor-related enterocolitis (irEC) in the investigator-sponsored trial (IST) conducted by Memorial Sloan Kettering Cancer Center (MSK) IST data support SER-155 as a potential treatment for irEC that may allow patients to continue cancer therapy; Company evaluating irEC clinical development strategy in consultation with KOLs Seres engaging potential partners, seeking capital to advance its SER-155 programs, including for the prevention of bloodstream infections in patients undergoing allo-HCT and those experiencing irEC Seres announces agreement to exit additional leased space early, further reducing ongoing facility-related cash costs, which follows announcement of balance sheet strengthening and facilities cost reduction transactions in June 2026 CAMBRIDGE, Mass., Aug. 05, 2026 (GLOBE NEWSWIRE) -- Seres Therapeutics, Inc. (Nasdaq: MCRB), (Seres or the Company), a leading live biotherapeutics company, today reported second quarter 2026 financial results and provided business updates.

Seres Therapeutics' SER-155 Posts 80% Response in Cancer Immunotherapy GI Toxicity Study

marketbeat.com · 10 Jul 2026

Seres Therapeutics' SER-155 Posts 80% Response in Cancer Immunotherapy GI Toxicity Study

Seres Therapeutics NASDAQ: MCRB reported results from an investigator-sponsored study of SER-155 in immune checkpoint inhibitor-related enterocolitis, or irEC, saying the data support further evaluation of the live biotherapeutic as a potential non-immunosuppressive treatment option for cancer patients experiencing the gastrointestinal toxicity.

Seres Therapeutics Posts Early Data for Cancer Therapy Complication

benzinga.com · 8 Jul 2026

Seres Therapeutics Posts Early Data for Cancer Therapy Complication

Seres Therapeutics Inc. (NASDAQ:MCRB) on Wednesday reported topline results from an investigator-sponsored trial evaluating SER-155 in patients with immune-related enterocolitis (irEC), with most participants achieving a steroid-free clinical response after treatment.

Seres Therapeutics, Inc. (MCRB) Discusses Promising SER-155 Clinical Trial Results for Immune Checkpoint Inhibitor Related Andropilatis Transcript

seekingalpha.com · 8 Jul 2026

Seres Therapeutics, Inc. (MCRB) Discusses Promising SER-155 Clinical Trial Results for Immune Checkpoint Inhibitor Related Andropilatis Transcript

Seres Therapeutics, Inc. (MCRB) Discusses Promising SER-155 Clinical Trial Results for Immune Checkpoint Inhibitor Related Andropilatis Transcript

Seres Therapeutics Announces Early Clinical Data Showing Potential for SER-155 in Immune Checkpoint Inhibitor-Related Enterocolitis (irEC), a Frequent Adverse Reaction That Forces Many Patients to Halt Cancer Treatment

globenewswire.com · 8 Jul 2026

Seres Therapeutics Announces Early Clinical Data Showing Potential for SER-155 in Immune Checkpoint Inhibitor-Related Enterocolitis (irEC), a Frequent Adverse Reaction That Forces Many Patients to Halt Cancer Treatment

80% of SER-155 recipients achieved immunosuppressive-free clinical response of diarrhea (a primary symptom of irEC) at Day 15 in the Investigator-Sponsored Trial (IST) conducted by Memorial Sloan Kettering Cancer Center (MSK) SER-155 has potential to treat irEC, a frequent side effect of immune checkpoint inhibitors (ICIs) that often causes halting of cancer treatment, without requiring treatment with systemic immunosuppressive drugs SER-155 was well tolerated, with no drug-related serious adverse events observed Drug pharmacology data provide confirmatory evidence of Seres' live biotherapeutics operating as designed to repair the mucosal epithelial barrier and reduce gastrointestinal inflammation, which supports possible expansion into multiple other inflammatory and immune diseases Company to host webcast today, July 8, at 8:30 am ET CAMBRIDGE, Mass., July 08, 2026 (GLOBE NEWSWIRE) -- Seres Therapeutics, Inc. (Nasdaq: MCRB), (Seres or the Company), a leading live biotherapeutics company, today announced encouraging top-line results from an IST evaluating SER-155 in patients with irEC.

Seres Therapeutics to Host Webcast on July 8, 2026, to Discuss Results of Investigator-Sponsored Trial of Seres' SER-155 in Immune Checkpoint Inhibitor-Related Enterocolitis

globenewswire.com · 25 Jun 2026

Seres Therapeutics to Host Webcast on July 8, 2026, to Discuss Results of Investigator-Sponsored Trial of Seres' SER-155 in Immune Checkpoint Inhibitor-Related Enterocolitis

CAMBRIDGE, Mass., June 25, 2026 (GLOBE NEWSWIRE) -- Seres Therapeutics, Inc. (Nasdaq: MCRB), a leading live biotherapeutics company, today announced that it will host a webcast to discuss top-line results from an investigator-sponsored trial (IST) evaluating SER-155 in patients with immune checkpoint inhibitor-related enterocolitis, a serious and frequent side effect of immune checkpoint inhibitor cancer therapy.

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