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Lyell Immunopharma, Inc.

$11.96 -$17.02 (-58.73%)
NASDAQ · 11 Sep 2026 20:00 UTC
Previous Close
$12.2
Day Range
$11.7$13
Year Range
$11.47$45
Market Cap
293.07M
AVG Volume
155.29K
Trailing/Forward PE
-0.75/-
PEG ratio
-0.15
Dividend Yield
-
Next Earnings Date
2026-11-10
Primary Exchange
NASDAQUS
Revenue (USD)
025M50M75M100M202020212022202320242025
LYEL Revenue (USD) by year
PeriodRevenue (USD)
202536K
202461K
2023130K
202284.68M
202110.65M
20207.76M
Net Income (USD)
-400M-300M-200M-100M0202020212022202320242025
LYEL Net Income (USD) by year
PeriodNet Income (USD)
2025-274.45M
2024-342.99M
2023-234.63M
2022-183.12M
2021-250.22M
2020-204.47M
Operating Income (USD)
-400M-300M-200M-100M0202020212022202320242025
LYEL Operating Income (USD) by year
PeriodOperating Income (USD)
2025-203.07M
2024-358.75M
2023-250.73M
2022-190.41M
2021-206.15M
2020-211.94M
EBITDA (USD)
-300M-200M-100M0202020212022202320242025
LYEL EBITDA (USD) by year
PeriodEBITDA (USD)
2025-265.92M
2024-194.09M
2023-214.91M
2022-166.65M
2021-236.13M
2020-215.43M
Cash Flows (USD)
-300M-200M-100M0202020212022202320242025
LYEL Cash Flows (USD) by year
PeriodCash Flows (USD)
2025-150.8M
2024-162.86M
2023-166.38M
2022-193.83M
2021-191.71M
2020-212.35M
EPS (USD)
-15-10-50202020212022202320242025
LYEL EPS (USD) by year
PeriodEPS (USD)
2025-11.82
2024-1.31
2023-0.94
2022-0.74
2021-1.03
2020-0.86
Expenses (USD)
0100M200M300MR&DSG&ACapex202020212022202320242025
LYEL Expenses (USD) by year
PeriodExpenses (USD)
2025204.59M
2024224.11M
2023233.82M
2022282.9M
2021276.3M
2020283.5M
Cash & Debt (USD)
0200M400M600M800M202020212022202320242025
LYEL Cash & Debt (USD) by year
PeriodCash & Debt (USD)
2025247.22M
2024370.53M
2023546.22M
2022640.15M
2021614.79M
2020612.62M
Debt ratios
00.20.40.6202320242025
LYEL Debt ratios by year
PeriodDebt ratios
20250.23
20240.38
20230.58
Margins
-20000%-15000%-10000%-5000%0%5000%202020212022202320242025
LYEL Margins by year
PeriodMargins
2025100%
2024100%
2023-15074.62%
202280.55%
202134.38%
2020100%
Return on Capital
-150%-100%-50%0%202020212022202320242025
LYEL Return on Capital by year
PeriodReturn on Capital
2025-110.57%
2024-89.6%
2023-35.82%
2022-21.98%
2021-26.91%
2020-28.46%
Shares Outstanding
05M10M15M20M202020212022202320242025
LYEL Shares Outstanding by year
PeriodShares Outstanding
202517.09M
202413.33M
202312.65M
202212.48M
202112.14M
202012.33M
Book Value Per Share (USD)
020406080202020212022202320242025
LYEL Book Value Per Share (USD) by year
PeriodBook Value Per Share (USD)
202514.52
202428.73
202351.76
202266.78
202176.61
202058.27
Total Assets (USD)
0500M1B1.5B202020212022202320242025
LYEL Total Assets (USD) by year
PeriodTotal Assets (USD)
2025340.05M
2024490.86M
2023750.03M
2022937.56M
20211.13B
2020908.28M
Employee Count
010020030020212022202320242025
LYEL Employee Count by year
PeriodEmployee Count
2025161
2024300
2023224
2022274
2021219
Free Cash Flow Yield
-200%-150%-100%-50%0%med -65%Dec 24Apr 25Jul 25Oct 25Feb 26May 26Sep 26
LYEL Free Cash Flow Yield by year
PeriodFree Cash Flow Yield
Sep 26-47.94%
Sep 26-39.9%
Aug 26-39.46%
Aug 26-36.92%
Aug 26-41.1%
Aug 26-38.98%
Jul 26-47.49%
Jul 26-48.65%
Jul 26-46.13%
Jul 26-40.94%
Jul 26-43.73%
Jun 26-52.92%
Jun 26-48.23%
Jun 26-45.52%
Jun 26-51.33%
May 26-35.46%
May 26-35.19%
May 26-34.29%
May 26-31.79%
May 26-42.36%
Apr 26-39.37%
Apr 26-36.75%
Apr 26-39.4%
Apr 26-41.6%
Mar 26-44.85%
Mar 26-46.14%
Mar 26-41.52%
Mar 26-40.34%
Feb 26-37.76%
Feb 26-42.34%
Feb 26-35.07%
Feb 26-39.9%
Jan 26-37.76%
Jan 26-35.87%
Jan 26-38.14%
Jan 26-36.91%
Jan 26-31.27%
Dec 25-25.82%
Dec 25-27.19%
Dec 25-26.3%
Dec 25-35.89%
Nov 25-37.76%
Nov 25-47.37%
Nov 25-53.52%
Nov 25-66.4%
Oct 25-69.79%
Oct 25-65.91%
Oct 25-70.47%
Oct 25-70.42%
Oct 25-65.5%
Sep 25-90.62%
Sep 25-88.82%
Sep 25-90.69%
Sep 25-95.69%
Aug 25-104.94%
Aug 25-108.06%
Aug 25-109.9%
Aug 25-108.51%
Aug 25-108.12%
Jul 25-95.93%
Jul 25-128.94%
Jul 25-122.2%
Jul 25-122.96%
Jun 25-133.27%
Jun 25-137.1%
Jun 25-122.32%
Jun 25-93.37%
May 25-136.48%
May 25-142.52%
May 25-143.55%
May 25-152.75%
May 25-132.54%
Apr 25-135.78%
Apr 25-140.95%
Apr 25-139.34%
Apr 25-131.4%
Mar 25-112.94%
Mar 25-105.62%
Mar 25-104.36%
Mar 25-82.04%
Feb 25-85.73%
Feb 25-87.02%
Feb 25-99.93%
Feb 25-106.29%
Jan 25-103.23%
Jan 25-100.75%
Jan 25-105.92%
Jan 25-100.92%
Jan 25-87.33%
Dec 24-93.78%
Dec 24-99.52%
Dec 24-90.44%
Dec 24-67.43%
Nov 24-64.5%
Nov 24-64.16%
Nov 24-55.41%
Nov 24-49.96%
Nov 24-55.59%
Oct 24-67.16%
Oct 24-53.21%
Price to Sales
05000100001500020000med 4362.7Dec 24Apr 25Jul 25Oct 25Feb 26May 26Sep 26
LYEL Price to Sales by year
PeriodPrice to Sales
Sep 2610349.39
Sep 2612434.84
Aug 2612573.29
Aug 2613438.63
Aug 2612071.4
Aug 2612729.05
Jul 269131.47
Jul 268912.71
Jul 269399.62
Jul 2610592.22
Jul 269914.77
Jun 268192.91
Jun 268990.33
Jun 269526.65
Jun 268446.96
May 2612229.39
May 2612321.13
May 2612645.74
May 2613640.74
May 269890.2
Apr 2610640.39
Apr 2611400.08
Apr 2610630.9
Apr 2610070.63
Mar 269339.43
Mar 269078.28
Mar 2610089.62
Mar 2610007.3
Feb 2610693.46
Feb 269535
Feb 2611513.3
Feb 2610118.69
Jan 2610693.46
Jan 2611254.87
Jan 2610586.53
Jan 2610938.52
Jan 2612912.36
Dec 2515634.73
Dec 2514850.55
Dec 2515354.03
Dec 2511250.41
Nov 2510693.46
Nov 258523.58
Nov 257543.35
Nov 254317.09
Oct 254107.52
Oct 254349.14
Oct 254068.07
Oct 254070.54
Oct 254376.26
Sep 253163.24
Sep 253227.34
Sep 253160.77
Sep 252995.58
Aug 252731.77
Aug 252652.88
Aug 252608.5
Aug 252492.44
Aug 252501.52
Jul 252819.32
Jul 252097.47
Jul 252213.24
Jul 252199.62
Jun 252029.37
Jun 251972.62
Jun 252210.97
Jun 252896.5
May 251981.7
May 251897.71
May 251884.09
May 251747.8
May 252014.34
Apr 251966.27
Apr 251894.17
Apr 251916.02
Apr 252031.81
Mar 252363.9
Mar 252527.75
Mar 252558.34
Mar 253022.82
Feb 252892.63
Feb 252849.91
Feb 252481.72
Feb 252333.23
Jan 252402.39
Jan 252461.38
Jan 252341.36
Jan 252457.31
Jan 252839.74
Dec 242644.46
Dec 242491.89
Dec 242742.1
Dec 243677.83
Nov 243844.63
Nov 243864.98
Nov 244475.24
Nov 244963.44
Nov 245297.14
Oct 244384.33
Oct 245533.62
Price to Book
00.511.52med 0.73Dec 24Apr 25Jul 25Oct 25Feb 26May 26Sep 26
LYEL Price to Book by year
PeriodPrice to Book
Sep 261.2
Sep 261.44
Aug 261.45
Aug 261.55
Aug 261.39
Aug 261.47
Jul 261.03
Jul 261.01
Jul 261.06
Jul 261.2
Jul 261.12
Jun 260.93
Jun 261.02
Jun 261.08
Jun 260.96
May 261.39
May 261.4
May 261.43
May 261.55
May 261.43
Apr 261.54
Apr 261.65
Apr 261.54
Apr 261.46
Mar 261.35
Mar 261.32
Mar 261.46
Mar 261.25
Feb 261.33
Feb 261.19
Feb 261.43
Feb 261.26
Jan 261.33
Jan 261.4
Jan 261.32
Jan 261.36
Jan 261.61
Dec 251.95
Dec 251.85
Dec 251.91
Dec 251.4
Nov 251.33
Nov 251.06
Nov 250.94
Nov 250.87
Oct 250.82
Oct 250.87
Oct 250.82
Oct 250.82
Oct 250.88
Sep 250.63
Sep 250.65
Sep 250.63
Sep 250.6
Aug 250.55
Aug 250.53
Aug 250.52
Aug 250.48
Aug 250.48
Jul 250.54
Jul 250.41
Jul 250.43
Jul 250.42
Jun 250.39
Jun 250.38
Jun 250.43
Jun 250.56
May 250.38
May 250.37
May 250.36
May 250.28
May 250.32
Apr 250.31
Apr 250.3
Apr 250.31
Apr 250.32
Mar 250.38
Mar 250.4
Mar 250.41
Mar 250.36
Feb 250.34
Feb 250.34
Feb 250.29
Feb 250.28
Jan 250.29
Jan 250.29
Jan 250.28
Jan 250.29
Jan 250.34
Dec 240.31
Dec 240.3
Dec 240.33
Dec 240.44
Nov 240.46
Nov 240.46
Nov 240.53
Nov 240.59
Nov 240.5
Oct 240.42
Oct 240.53
Lyell Immunopharma, Inc.
LYEL
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News: LYEL

Lyell Immunopharma Completes Manufacturing Transfer for LYL273 and Provides Updated Timeline on Phase 1/2 Trial in Metastatic Colorectal Cancer

globenewswire.com · 10 Sep 2026

Lyell Immunopharma Completes Manufacturing Transfer for LYL273 and Provides Updated Timeline on Phase 1/2 Trial in Metastatic Colorectal Cancer

SOUTH SAN FRANCISCO, Calif., Sept. 10, 2026 (GLOBE NEWSWIRE) -- Lyell Immunopharma, Inc. (Nasdaq: LYEL), a late-stage clinical company advancing a pipeline of next-generation chimeric antigen receptor (CAR) T-cell therapies for patients with cancer, today announced successful completion of the planned technology transfer for LYL273, a guanylyl cyclase C (GCC)-targeted CAR T-cell product candidate, to its LyFE Manufacturing Center™ (LyFE) in Bothell, Washington, following review by the U.S. Food and Drug Administration (FDA). LyFE is implementing an improved manufacturing process and updated analytical methods to enhance manufacturing performance and increase capacity. The Phase 1/2 clinical trial of LYL273 in patients with relapsed/refractory metastatic colorectal cancer (R/R mCRC) continues to enroll patients with the goal of determining the recommended Phase 2 dose and optimized safety management plan. Additional clinical data from the trial and a planned End-of-Phase 1 meeting with the FDA are now expected in 2027.

This Lyell Immunopharma Analyst Begins Coverage On A Bullish Note; Here Are Top 3 Initiations For Thursday

benzinga.com · 6 Aug 2026

This Lyell Immunopharma Analyst Begins Coverage On A Bullish Note; Here Are Top 3 Initiations For Thursday

Top Wall Street analysts changed their outlook on these top names. For a complete view of all analyst rating changes, including upgrades, downgrades and initiations, please see our analyst ratings page.

Here Are Thursday’s Top Wall Street Analyst Research Calls: AppLovin, Charles River, Global Payments, HubSpot, Insulet Corporation, Roper Technologies, Sabra Health Care, Western Digital, Zillow Group, and More

247wallst.com · 6 Aug 2026

Here Are Thursday’s Top Wall Street Analyst Research Calls: AppLovin, Charles River, Global Payments, HubSpot, Insulet Corporation, Roper Technologies, Sabra Health Care, Western Digital, Zillow Group, and More

Wall Street analysts made some dramatic moves on Thursday, slashing price targets by double digits on several high-profile names while upgrading others to buy. Find out which stocks got the most surprising treatment before the opening bell.

Lyell Immunopharma, Inc. (NASDAQ:LYEL) Receives $43.00 Consensus Price Target from Analysts

defenseworld.net · 22 Jul 2026

Lyell Immunopharma, Inc. (NASDAQ:LYEL) Receives $43.00 Consensus Price Target from Analysts

Lyell Immunopharma, Inc. (NASDAQ: LYEL - Get Free Report) has received an average rating of "Moderate Buy" from the seven ratings firms that are currently covering the firm, Marketbeat.com reports. One analyst has rated the stock with a sell recommendation, one has given a hold recommendation, four have assigned a buy recommendation and one has issued

Wall Street Analysts Think Lyell Immunopharma (LYEL) Could Surge 176.02%: Read This Before Placing a Bet

zacks.com · 2 Jul 2026

Wall Street Analysts Think Lyell Immunopharma (LYEL) Could Surge 176.02%: Read This Before Placing a Bet

The average of price targets set by Wall Street analysts indicates a potential upside of 176% in Lyell Immunopharma (LYEL). While the effectiveness of this highly sought-after metric is questionable, the positive trend in earnings estimate revisions might translate into an upside in the stock.

Lyell Immunopharma Announces Participation in H.C. Wainwright 4th Annual Cell Therapy Virtual Conference

globenewswire.com · 25 Jun 2026

Lyell Immunopharma Announces Participation in H.C. Wainwright 4th Annual Cell Therapy Virtual Conference

SOUTH SAN FRANCISCO, Calif., June 25, 2026 (GLOBE NEWSWIRE) -- Lyell Immunopharma, Inc. (Nasdaq: LYEL), a late-stage clinical company advancing a pipeline of next-generation chimeric antigen receptor (CAR) T-cell therapies for patients with cancer, today announced that members of its senior management team will participate in a fireside chat at the H.C.

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