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Lexicon Pharmaceuticals, Inc.

$2 +$0.86 (+75.44%)
NASDAQ · 11 Sep 2026 20:00 UTC
Previous Close
$2.02
Day Range
$1.95$2.06
Year Range
$1.06$2.68
Market Cap
888.39M
AVG Volume
3.25M
Trailing/Forward PE
-13.3/-
PEG ratio
-0.57
Dividend Yield
-
Next Earnings Date
2026-11-05
Primary Exchange
NASDAQUS
Revenue (USD)
0100M200M300M400M2016201720182019202020212022202320242025
LXRX Revenue (USD) by year
PeriodRevenue (USD)
202549.8M
202431.08M
20231.21M
2022139K
2021298K
202024M
2019322.07M
201862.89M
201790.33M
201683.34M
Net Income (USD)
-300M-200M-100M0100M200M2016201720182019202020212022202320242025
LXRX Net Income (USD) by year
PeriodNet Income (USD)
2025-50.34M
2024-200.4M
2023-177.12M
2022-101.94M
2021-87.76M
2020-58.57M
2019130.13M
2018-121.07M
2017-129.05M
2016-141.43M
Operating Income (USD)
-200M-100M0100M200M2016201720182019202020212022202320242025
LXRX Operating Income (USD) by year
PeriodOperating Income (USD)
2025-48.91M
2024-197.12M
2023-171.75M
2022-100.76M
2021-87.09M
2020-47.8M
2019141.44M
2018-103.81M
2017-136.68M
2016-137.16M
EBITDA (USD)
-200M-100M0100M200M2016201720182019202020212022202320242025
LXRX EBITDA (USD) by year
PeriodEBITDA (USD)
2025-41.38M
2024-175.97M
2023-164.43M
2022-98.74M
2021-86.66M
2020-41.8M
2019148.45M
2018-96.71M
2017-130.77M
2016-132.88M
Cash Flows (USD)
-200M-100M0100M200M2016201720182019202020212022202320242025
LXRX Cash Flows (USD) by year
PeriodCash Flows (USD)
2025-67.85M
2024-179.81M
2023-162.37M
2022-90.18M
2021-88.24M
2020-143.06M
2019113.74M
2018-148.7M
2017-185.62M
2016-175.86M
EPS (USD)
-2-10122016201720182019202020212022202320242025
LXRX EPS (USD) by year
PeriodEPS (USD)
2025-0.14
2024-0.64
2023-0.79
2022-0.63
2021-0.61
2020-0.61
20191.04
2018-1.15
2017-1.22
2016-1.37
Expenses (USD)
0100M200M300MR&DSG&ACapex2016201720182019202020212022202320242025
LXRX Expenses (USD) by year
PeriodExpenses (USD)
202598.14M
2024196.21M
2023140.73M
2022102.01M
202163.57M
2020194.51M
2019148.83M
2018164.3M
2017223.24M
2016221.43M
Cash & Debt (USD)
0100M200M300M400MCashLong Term DebtShort Term Debt2016201720182019202020212022202320242025
LXRX Cash & Debt (USD) by year
PeriodCash & Debt (USD)
202596.23M
2024237.96M
2023170.03M
2022138.36M
202186.74M
2020152.28M
2019271.66M
2018160.05M
2017310.79M
2016346.5M
Debt ratios
-0.500.511.520182019202020212022202320242025
LXRX Debt ratios by year
PeriodDebt ratios
20250.07
20240.25
20230.16
20221.05
20211.1
20201.15
20190.12
2018-0.24
Margins
-15000%-10000%-5000%0%5000%2016201720182019202020212022202320242025
LXRX Margins by year
PeriodMargins
202598.86%
202415.24%
2023-1132.12%
2022-52.52%
2021-13109.4%
202087.83%
201999%
201896.04%
201797.9%
2016-113.77%
Return on Capital
-400%-200%0%200%400%600%2016201720182019202020212022202320242025
LXRX Return on Capital by year
PeriodReturn on Capital
2025-46.81%
2024-137.31%
2023-190.23%
2022-87.04%
2021-77.26%
2020-37.46%
2019111.13%
2018458.53%
2017-247.69%
2016-89.85%
Shares Outstanding
0100M200M300M400M2016201720182019202020212022202320242025
LXRX Shares Outstanding by year
PeriodShares Outstanding
2025363.43M
2024361.49M
2023244.93M
2022188.73M
2021148.9M
2020122.36M
2019106.27M
2018104.8M
2017105.59M
2016104.05M
Book Value Per Share (USD)
-0.500.511.522016201720182019202020212022202320242025
LXRX Book Value Per Share (USD) by year
PeriodBook Value Per Share (USD)
20250.3
20240.4
20230.38
20220.62
20210.76
20201.28
20191.1
2018-0.25
20170.49
20161.51
Total Assets (USD)
0200M400M600M2016201720182019202020212022202320242025
LXRX Total Assets (USD) by year
PeriodTotal Assets (USD)
2025184.99M
2024298.42M
2023229.43M
2022194.3M
2021136.91M
2020203.79M
2019417.71M
2018284.14M
2017436.54M
2016475.62M
Employee Count
01002003002016201720182019202020212022202320242025
LXRX Employee Count by year
PeriodEmployee Count
202581
2024103
2023285
2022135
202187
202078
2019184
2018202
2017174
2016168
PE Ratio
0102030med 2.61Dec 19Feb 20Apr 20Jul 20Sep 20Aug 21Nov 21
LXRX PE Ratio by year
PeriodPE Ratio
Nov 2118.36
Oct 2120.07
Oct 2119.34
Oct 2123.37
Oct 2121.13
Oct 2118.28
Sep 2118.74
Sep 2118.43
Sep 2117.68
Sep 2118.85
Aug 2117.49
Aug 2113.16
Aug 2113.77
Aug 2113.5
Oct 203.63
Oct 204.01
Oct 204.25
Oct 203.95
Sep 204.14
Sep 204.42
Sep 204.17
Sep 204.36
Aug 204.74
Aug 204.8
Aug 204.94
Aug 205.02
Jul 205.29
Jul 202.16
Jul 202.62
Jul 202.42
Jul 202.42
Jun 202.53
Jun 202.43
Jun 202.34
Jun 202.43
May 202.38
May 202.51
May 202.35
May 202.41
May 202.37
Apr 201.67
Apr 201.54
Apr 201.54
Apr 201.44
Mar 201.47
Mar 201.64
Mar 201.66
Mar 201.52
Feb 201.8
Feb 201.74
Feb 201.87
Feb 201.95
Jan 202
Jan 202.17
Jan 202.61
Jan 202.6
Jan 202.55
Dec 192.75
Dec 192.85
Dec 193.14
Dec 193.15
Nov 192.28
Nov 192.49
Nov 192.28
Nov 192.27
Free Cash Flow Yield
-150%-100%-50%0%med -20.33%Dec 24Apr 25Jul 25Oct 25Feb 26May 26Sep 26
LXRX Free Cash Flow Yield by year
PeriodFree Cash Flow Yield
Sep 26-9.11%
Sep 26-8.13%
Aug 26-7.95%
Aug 26-7.92%
Aug 26-7.85%
Aug 26-7.37%
Jul 26-4.2%
Jul 26-4.23%
Jul 26-4.06%
Jul 26-4.37%
Jul 26-4.18%
Jun 26-3.8%
Jun 26-4.82%
Jun 26-5.05%
Jun 26-5.08%
May 26-4.45%
May 26-4.49%
May 26-4.35%
May 26-4.85%
May 26-11.45%
Apr 26-11.11%
Apr 26-9.98%
Apr 26-10.85%
Apr 26-11.74%
Mar 26-11.31%
Mar 26-11.97%
Mar 26-11.05%
Mar 26-10.92%
Feb 26-13.59%
Feb 26-13.59%
Feb 26-15.25%
Feb 26-16.24%
Jan 26-17.22%
Jan 26-11.75%
Jan 26-14.58%
Jan 26-17.07%
Jan 26-17.52%
Dec 25-16.24%
Dec 25-17.07%
Dec 25-15.36%
Dec 25-14.27%
Nov 25-13.97%
Nov 25-14.91%
Nov 25-13.4%
Nov 25-15.98%
Oct 25-20.48%
Oct 25-19.9%
Oct 25-19.9%
Oct 25-18.97%
Oct 25-20.04%
Sep 25-20.19%
Sep 25-23.75%
Sep 25-24.58%
Sep 25-25.93%
Aug 25-25.69%
Aug 25-23.75%
Aug 25-22.79%
Aug 25-26.17%
Aug 25-43.48%
Jul 25-42.3%
Jul 25-37.83%
Jul 25-43.08%
Jul 25-51.64%
Jun 25-56.68%
Jun 25-62.04%
Jun 25-69.29%
Jun 25-60.68%
May 25-74.25%
May 25-70.51%
May 25-86.93%
May 25-70.96%
May 25-73.08%
Apr 25-70.22%
Apr 25-97.57%
Apr 25-97.19%
Apr 25-118.74%
Mar 25-87.19%
Mar 25-136.95%
Mar 25-135.72%
Mar 25-126.96%
Feb 25-82.41%
Feb 25-81.19%
Feb 25-73.45%
Feb 25-80.8%
Jan 25-76.23%
Jan 25-58.23%
Jan 25-83.55%
Jan 25-75.24%
Jan 25-73.1%
Dec 24-74.54%
Dec 24-80.66%
Dec 24-71.14%
Dec 24-81.76%
Nov 24-71.73%
Nov 24-66.77%
Nov 24-59.11%
Nov 24-49.69%
Nov 24-51.73%
Oct 24-35.06%
Oct 24-30.34%
Price to Sales
050100150200med 11.21Dec 24Apr 25Jul 25Oct 25Feb 26May 26Sep 26
LXRX Price to Sales by year
PeriodPrice to Sales
Sep 2621.11
Sep 2623.64
Aug 2624.17
Aug 2624.27
Aug 2624.48
Aug 2626.07
Jul 2613.28
Jul 2613.16
Jul 2613.74
Jul 2612.76
Jul 2613.33
Jun 2614.65
Jun 2611.55
Jun 2611.03
Jun 2610.98
May 2612.53
May 2612.41
May 2612.82
May 2611.49
May 2611.89
Apr 2612.26
Apr 2613.65
Apr 2612.55
Apr 2611.6
Mar 2612.04
Mar 2611.38
Mar 2612.33
Mar 2612.48
Feb 267.54
Feb 267.54
Feb 266.72
Feb 266.31
Jan 265.95
Jan 268.72
Jan 267.03
Jan 266
Jan 265.85
Dec 256.31
Dec 256
Dec 256.67
Dec 257.18
Nov 257.33
Nov 256.87
Nov 257.64
Nov 256.41
Oct 258.58
Oct 258.83
Oct 258.83
Oct 259.26
Oct 258.77
Sep 258.7
Sep 257.4
Sep 257.15
Sep 256.78
Aug 256.84
Aug 257.4
Aug 257.71
Aug 256.71
Aug 2512.41
Jul 2512.76
Jul 2514.27
Jul 2512.53
Jul 2510.45
Jun 259.52
Jun 258.7
Jun 257.79
Jun 258.89
May 257.27
May 257.65
May 256.21
May 258.15
May 257.92
Apr 258.24
Apr 255.93
Apr 255.95
Apr 254.87
Mar 256.64
Mar 254.22
Mar 254.26
Mar 254.56
Feb 2548.36
Feb 2549.08
Feb 2554.26
Feb 2549.33
Jan 2552.28
Jan 2568.44
Jan 2547.7
Jan 2552.97
Jan 2554.52
Dec 2453.47
Dec 2449.41
Dec 2456.02
Dec 2448.75
Nov 2455.56
Nov 2459.69
Nov 2467.42
Nov 24108.42
Nov 24104.15
Oct 24153.67
Oct 24177.57
EV/EBITDA
05101520med 2.07Dec 19Feb 20Apr 20Jul 20Sep 20Aug 21Nov 21
LXRX EV/EBITDA by year
PeriodEV/EBITDA
Nov 2113.73
Oct 2115.23
Oct 2114.6
Oct 2118.14
Oct 2116.17
Oct 2113.66
Sep 2114.06
Sep 2113.8
Sep 2113.13
Sep 2114.16
Aug 2112.96
Aug 219.15
Aug 219.69
Aug 219.45
Oct 203.24
Oct 203.5
Oct 203.67
Oct 203.46
Sep 203.59
Sep 203.78
Sep 203.61
Sep 203.74
Aug 204
Aug 204.04
Aug 204.13
Aug 204.19
Jul 204.37
Jul 201.74
Jul 202.12
Jul 201.96
Jul 201.96
Jun 202.05
Jun 201.97
Jun 201.88
Jun 201.97
May 201.93
May 202.03
May 201.89
May 201.95
May 201.92
Apr 201.3
Apr 201.18
Apr 201.18
Apr 201.09
Mar 201.12
Mar 201.27
Mar 201.29
Mar 201.09
Feb 201.34
Feb 201.28
Feb 201.41
Feb 201.48
Jan 201.52
Jan 201.67
Jan 202.07
Jan 202.06
Jan 202.01
Dec 192.2
Dec 192.28
Dec 192.55
Dec 192.55
Nov 191.77
Nov 191.96
Nov 191.77
Nov 191.77
Price/Operating Cashflow
051015med 2.42Dec 16Nov 19Jan 20Mar 20Jun 20Aug 20Oct 20
LXRX Price/Operating Cashflow by year
PeriodPrice/Operating Cashflow
Oct 201.45
Oct 201.61
Oct 201.7
Oct 201.58
Sep 201.66
Sep 201.77
Sep 201.67
Sep 201.75
Aug 201.9
Aug 201.92
Aug 201.98
Aug 202.01
Jul 202.12
Jul 201.57
Jul 201.91
Jul 201.76
Jul 201.76
Jun 201.84
Jun 201.77
Jun 201.7
Jun 201.77
May 201.73
May 201.82
May 201.71
May 201.75
May 201.72
Apr 201.91
Apr 201.76
Apr 201.76
Apr 201.64
Mar 201.68
Mar 201.88
Mar 201.9
Mar 202.26
Feb 202.66
Feb 202.57
Feb 202.78
Feb 202.89
Jan 202.96
Jan 203.22
Jan 203.87
Jan 203.86
Jan 203.77
Dec 194.08
Dec 194.22
Dec 194.65
Dec 194.66
Nov 193.38
Nov 193.68
Nov 193.38
Nov 193.37
Mar 1712.02
Feb 1711.74
Feb 1711.76
Feb 1711.4
Feb 1710.74
Jan 1710.38
Jan 1710.34
Jan 1711.02
Jan 1710.91
Dec 1610.33
Dec 1611.34
Dec 1612.58
Dec 1611.65
Dec 1611.19
Nov 1612.47
Nov 1612.5
Nov 1612.27
Price to Book
02468med 3.52Dec 24Apr 25Jul 25Oct 25Feb 26May 26Sep 26
LXRX Price to Book by year
PeriodPrice to Book
Sep 265.02
Sep 265.62
Aug 265.74
Aug 265.77
Aug 265.82
Aug 266.19
Jul 264.56
Jul 264.52
Jul 264.72
Jul 264.38
Jul 264.58
Jun 265.03
Jun 263.97
Jun 263.79
Jun 263.77
May 264.3
May 264.26
May 264.4
May 263.95
May 265.51
Apr 265.68
Apr 266.32
Apr 265.81
Apr 265.37
Mar 265.58
Mar 265.27
Mar 265.71
Mar 265.78
Feb 264.45
Feb 264.45
Feb 263.96
Feb 263.72
Jan 263.51
Jan 265.14
Jan 264.14
Jan 263.54
Jan 263.45
Dec 253.72
Dec 253.54
Dec 253.93
Dec 254.23
Nov 254.32
Nov 254.05
Nov 254.51
Nov 253.78
Oct 253.87
Oct 253.99
Oct 253.99
Oct 254.18
Oct 253.96
Sep 253.93
Sep 253.34
Sep 253.23
Sep 253.06
Aug 253.09
Aug 253.34
Aug 253.48
Aug 253.03
Aug 253.15
Jul 253.24
Jul 253.62
Jul 253.18
Jul 252.65
Jun 252.42
Jun 252.21
Jun 251.98
Jun 252.26
May 251.84
May 251.94
May 251.58
May 251.74
May 251.69
Apr 251.75
Apr 251.26
Apr 251.27
Apr 251.04
Mar 251.41
Mar 250.9
Mar 250.91
Mar 250.97
Feb 251.42
Feb 251.44
Feb 251.59
Feb 251.44
Jan 251.53
Jan 252
Jan 251.4
Jan 251.55
Jan 251.6
Dec 241.57
Dec 241.45
Dec 241.64
Dec 241.43
Nov 241.63
Nov 241.75
Nov 241.97
Nov 241.64
Nov 241.58
Oct 242.33
Oct 242.69
Lexicon Pharmaceuticals, Inc.
LXRX
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News: LXRX

Lexicon Pharmaceuticals, Inc. (LXRX) Presents at Citigroup's Biopharma Back to School Summit 2026 Transcript

seekingalpha.com · 9 Sep 2026

Lexicon Pharmaceuticals, Inc. (LXRX) Presents at Citigroup's Biopharma Back to School Summit 2026 Transcript

Lexicon Pharmaceuticals, Inc. (LXRX) Presents at Citigroup's Biopharma Back to School Summit 2026 Transcript

Lexicon Pharmaceuticals to Participate at Three Upcoming Investor Conferences

globenewswire.com · 1 Sep 2026

Lexicon Pharmaceuticals to Participate at Three Upcoming Investor Conferences

THE WOODLANDS, Texas, Sept. 01, 2026 (GLOBE NEWSWIRE) -- Lexicon Pharmaceuticals, Inc. (Nasdaq: LXRX) today announced that company management will present at three upcoming investor conferences taking place in New York, NY:

Lexicon Announces New Post Hoc SOLOIST-WHF Analysis Demonstrating Consistent Sotagliflozin Results Across Baseline Blood Pressure Levels in Patients with Recent Worsening Heart Failure

globenewswire.com · 31 Aug 2026

Lexicon Announces New Post Hoc SOLOIST-WHF Analysis Demonstrating Consistent Sotagliflozin Results Across Baseline Blood Pressure Levels in Patients with Recent Worsening Heart Failure

Findings presented at ESC Congress 2026 and simultaneously published in JACC: Heart Failure Findings presented at ESC Congress 2026 and simultaneously published in JACC: Heart Failure

Lexicon Pharmaceuticals Earns Third $10 Million Milestone Payment from Novo Nordisk Following Achievement of Key Phase 1 Development Milestone for LX9851

globenewswire.com · 24 Aug 2026

Lexicon Pharmaceuticals Earns Third $10 Million Milestone Payment from Novo Nordisk Following Achievement of Key Phase 1 Development Milestone for LX9851

LX9851 is a first-in-class, oral non-incretin candidate being developed by Novo Nordisk for the treatment of obesity and associated metabolic disorders

Lexicon Pharmaceuticals Edging Closer To 'Go Time' On Multiple Late-Stage Assets

seekingalpha.com · 19 Aug 2026

Lexicon Pharmaceuticals Edging Closer To 'Go Time' On Multiple Late-Stage Assets

Lexicon Pharmaceuticals (LXRX) is nearing multiple potential value-transforming events for sotagliflozin, and the shares have been strong since my last update. Sotagliflozin, targeting HCM and T1D, is the primary value driver; the pivotal SONATA-HCM Phase III readout is expected in 2027, and an NDA re-filing for T1D before year-end. Regulatory and commercialization risks arguably outweigh clinical risk, especially for T1D, as the company would have to commit considerable resources to commercialization to maximize the value of sotagliflozin.

Lexicon Pharmaceuticals Q2 Earnings Call Highlights

marketbeat.com · 6 Aug 2026

Lexicon Pharmaceuticals Q2 Earnings Call Highlights

Lexicon Pharmaceuticals NASDAQ: LXRX reported a wider second-quarter loss as revenue declined sharply from the prior-year period, while the company highlighted completed enrollment in its Phase III SONATA-HCM trial and outlined plans to resubmit a new drug application for ZYNQUISTA in type 1 diabetes during the fourth quarter.

Lexicon Pharmaceuticals, Inc. (LXRX) Q2 2026 Earnings Call Transcript

seekingalpha.com · 6 Aug 2026

Lexicon Pharmaceuticals, Inc. (LXRX) Q2 2026 Earnings Call Transcript

Lexicon Pharmaceuticals, Inc. (LXRX) Q2 2026 Earnings Call Transcript

Lexicon Pharmaceuticals (LXRX) Reports Q2 Loss, Lags Revenue Estimates

zacks.com · 6 Aug 2026

Lexicon Pharmaceuticals (LXRX) Reports Q2 Loss, Lags Revenue Estimates

Lexicon Pharmaceuticals (LXRX) came out with a quarterly loss of $0.06 per share in line with the Zacks Consensus Estimate. This compares to earnings of $0.01 per share a year ago.

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