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Alnylam Pharmaceuticals, Inc.

€206.4 -$133.30 (-39.24%)

XETRA · 16 Sep 2026 08:43 UTC

Previous Close

€206.2

Day Range

€206.4€207.2

Year Range

€177.1€407.5

Market Cap

27.62B

AVG Volume

140

Trailing/Forward PE

39.06/20.78

PEG ratio

0.77

Dividend Yield

Next Earnings Date

2026-10-29

Primary Exchange

Deutsche Börse

Revenue (USD)

DUL.DE Revenue (USD) by year
Period	Revenue (USD)
2025	3.71B
2024	2.25B
2023	1.83B
2022	1.04B
2021	844.29M
2020	492.85M
2019	219.75M
2018	74.91M
2017	89.91M
2016	47.16M

Net Income (USD)

DUL.DE Net Income (USD) by year
Period	Net Income (USD)
2025	313.63M
2024	-278.16M
2023	-440.24M
2022	-1.13B
2021	-852.82M
2020	-858.28M
2019	-886.12M
2018	-761.5M
2017	-490.87M
2016	-410.11M

Operating Income (USD)

DUL.DE Operating Income (USD) by year
Period	Operating Income (USD)
2025	501M
2024	-176.88M
2023	-282.18M
2022	-785.07M
2021	-708.65M
2020	-828.44M
2019	-939.43M
2018	-814.67M
2017	-500.09M
2016	-424.59M

EBITDA (USD)

DUL.DE EBITDA (USD) by year
Period	EBITDA (USD)
2025	630.8M
2024	-271.19M
2023	-245.44M
2022	-908.84M
2021	-660.71M
2020	-754M
2019	-885.06M
2018	-806.01M
2017	-486.72M
2016	-409.46M

Cash Flows (USD)

DUL.DE Cash Flows (USD) by year
Period	Cash Flows (USD)
2025	465.39M
2024	-42.59M
2023	41.95M
2022	-613.33M
2021	-718.07M
2020	-685.32M
2019	-418.58M
2018	-689.5M
2017	-487M
2016	-372.26M

EPS (USD)

DUL.DE EPS (USD) by year
Period	EPS (USD)
2025	2.26
2024	-2.17
2023	-3.7
2022	-9.41
2021	-7.22
2020	-7.45
2019	-8.14
2018	-7.56
2017	-5.41
2016	-4.79

Expenses (USD)

DUL.DE Expenses (USD) by year
Period	Expenses (USD)
2025	2.58B
2024	2.14B
2023	1.86B
2022	1.73B
2021	1.49B
2020	1.31B
2019	1.27B
2018	1.01B
2017	694.21M
2016	536.3M

Cash & Debt (USD)

DUL.DE Cash & Debt (USD) by year
Period	Cash & Debt (USD)
2025	2.91B
2024	2.69B
2023	2.44B
2022	2.19B
2021	2.44B
2020	1.87B
2019	1.54B
2018	1.08B
2017	1.69B
2016	626.8M

Debt ratios

DUL.DE Debt ratios by year
Period	Debt ratios
2025	-0.36
2024	-0.02
2023	0.33
2022	-0.13
2021	0.08
2020	0.1
2019	0.48
2018	0.53

Margins

DUL.DE Margins by year
Period	Margins
2025	81.64%
2024	85.62%
2023	83.02%
2022	83.73%
2021	83.4%
2020	84.16%
2019	88.6%
2018	97.59%
2017	100%
2016	100%

Return on Capital

DUL.DE Return on Capital by year
Period	Return on Capital
2025	39.74%
2024	-414.62%
2023	199.53%
2022	714.91%
2021	-144.99%
2020	-84.46%
2019	-61.59%
2018	-58.49%
2017	-27.79%
2016	-44.57%

Shares Outstanding

DUL.DE Shares Outstanding by year
Period	Shares Outstanding
2025	132.23M
2024	129.12M
2023	125.61M
2022	119.77M
2021	119.77M
2020	116.27M
2019	111.75M
2018	101.07M
2017	96.14M
2016	85.84M

Book Value Per Share (USD)

DUL.DE Book Value Per Share (USD) by year
Period	Book Value Per Share (USD)
2025	5.97
2024	0.52
2023	-1.76
2022	-1.32
2021	4.91
2020	8.74
2019	12.87
2018	12.88
2017	18.37
2016	10.72

Total Assets (USD)

DUL.DE Total Assets (USD) by year
Period	Total Assets (USD)
2025	5.03B
2024	4.24B
2023	3.83B
2022	3.55B
2021	3.64B
2020	3.41B
2019	2.4B
2018	1.57B
2017	1.99B
2016	1.26B

PE Ratio

DUL.DE PE Ratio by year
Period	PE Ratio
Sep 26	55.08
Sep 26	57.36
Sep 26	61.22
Aug 26	54.51
Aug 26	54.32
Aug 26	52.52
Aug 26	50.41
Jul 26	47.25
Jul 26	62.52
Jul 26	61.76
Jul 26	68.88
Jul 26	72.85
Jun 26	122.93
Jun 26	116.58
Jun 26	119.24
Jun 26	127.32
May 26	126.59
May 26	125.34
May 26	121.22
May 26	124.68
Apr 26	130.07
Apr 26	128.63
Apr 26	130.34
Apr 26	135.99
Apr 26	134.5
Mar 26	956.66
Mar 26	946.69
Mar 26	951.27
Mar 26	972.46
Feb 26	1008.38
Feb 26	1020.69
Feb 26	948.56
Feb 26	993.9
Jan 26	1025.9
Jan 26	1088.17
Jan 26	1083.94
Jan 26	1204.64
Jan 26	1205.24

Free Cash Flow Yield

DUL.DE Free Cash Flow Yield by year
Period	Free Cash Flow Yield
Sep 26	2.02%
Sep 26	1.94%
Sep 26	1.82%
Aug 26	2.04%
Aug 26	2.05%
Aug 26	2.12%
Aug 26	2.2%
Jul 26	2.35%
Jul 26	1.78%
Jul 26	1.8%
Jul 26	1.61%
Jul 26	1.53%
Jun 26	1.21%
Jun 26	1.27%
Jun 26	1.24%
Jun 26	1.17%
May 26	1.17%
May 26	1.18%
May 26	1.22%
May 26	1.19%
Apr 26	1.14%
Apr 26	1.15%
Apr 26	1.14%
Apr 26	1.09%
Apr 26	1.1%
Mar 26	0.53%
Mar 26	0.54%
Mar 26	0.54%
Mar 26	0.52%
Feb 26	0.51%
Feb 26	0.5%
Feb 26	0.54%
Feb 26	0.51%
Jan 26	0.5%
Jan 26	0.47%
Jan 26	0.47%
Jan 26	0.42%
Jan 26	0.42%
Dec 25	-0.1%
Dec 25	-0.1%
Dec 25	-0.1%
Dec 25	-0.09%
Nov 25	-0.09%
Nov 25	-0.09%
Nov 25	-0.09%
Nov 25	-0.09%
Oct 25	-0.09%
Oct 25	-0.09%
Oct 25	-0.08%
Oct 25	-0.09%
Oct 25	-0.09%
Sep 25	-0.13%
Sep 25	-0.13%
Sep 25	-0.12%
Sep 25	-0.13%
Aug 25	-0.13%
Aug 25	-0.13%
Aug 25	-0.13%
Aug 25	-0.13%
Aug 25	-0.15%
Jul 25	-0.18%
Jul 25	-0.18%
Jul 25	-0.18%
Jul 25	-0.18%
Jun 25	-0.1%
Jun 25	-0.11%
Jun 25	-0.11%
Jun 25	-0.11%
May 25	-0.11%
May 25	-0.11%
May 25	-0.12%
May 25	-0.13%
May 25	-0.13%
Apr 25	-0.13%
Apr 25	-0.14%
Apr 25	-0.14%
Apr 25	-0.14%
Mar 25	0.05%
Mar 25	0.04%
Mar 25	0.05%
Mar 25	0.05%
Feb 25	0.05%
Feb 25	0.05%
Feb 25	0.05%
Feb 25	0.05%
Jan 25	0.05%
Jan 25	0.05%
Jan 25	0.05%
Jan 25	0.05%
Jan 25	0.05%
Dec 24	1.05%
Dec 24	1.03%
Dec 24	1.03%
Dec 24	0.99%
Nov 24	0.99%
Nov 24	1.03%
Nov 24	1.06%
Nov 24	0.91%
Nov 24	0.92%
Oct 24	0.88%

Price to Sales

DUL.DE Price to Sales by year
Period	Price to Sales
Sep 26	7.43
Sep 26	7.73
Sep 26	8.25
Aug 26	7.35
Aug 26	7.32
Aug 26	7.08
Aug 26	6.8
Jul 26	6.37
Jul 26	8.43
Jul 26	8.33
Jul 26	9.29
Jul 26	9.82
Jun 26	10.4
Jun 26	9.86
Jun 26	10.09
Jun 26	10.77
May 26	10.71
May 26	10.6
May 26	10.25
May 26	10.55
Apr 26	11
Apr 26	10.88
Apr 26	11.02
Apr 26	11.5
Apr 26	11.38
Mar 26	12.97
Mar 26	12.83
Mar 26	12.9
Mar 26	13.18
Feb 26	13.67
Feb 26	13.84
Feb 26	12.86
Feb 26	13.47
Jan 26	13.91
Jan 26	14.75
Jan 26	14.69
Jan 26	16.33
Jan 26	16.34
Dec 25	21.15
Dec 25	21.35
Dec 25	21.06
Dec 25	24.41
Nov 25	24.1
Nov 25	23.15
Nov 25	23.93
Nov 25	23.46
Oct 25	24.33
Oct 25	24.55
Oct 25	25.35
Oct 25	24.44
Oct 25	24.35
Sep 25	24.72
Sep 25	25.02
Sep 25	25.82
Sep 25	25.05
Aug 25	24.7
Aug 25	25.19
Aug 25	24.75
Aug 25	24.15
Aug 25	22.08
Jul 25	18.17
Jul 25	17.63
Jul 25	17.36
Jul 25	18.2
Jun 25	18.44
Jun 25	17.81
Jun 25	17.66
Jun 25	17.32
May 25	17.48
May 25	16.6
May 25	16.38
May 25	14.44
May 25	14.93
Apr 25	14.41
Apr 25	13.41
Apr 25	13.72
Apr 25	13.62
Mar 25	16.43
Mar 25	17.28
Mar 25	14.8
Mar 25	15.03
Feb 25	15.08
Feb 25	15.29
Feb 25	15.59
Feb 25	16.91
Jan 25	16.75
Jan 25	17.03
Jan 25	15.08
Jan 25	14.49
Jan 25	14.3
Dec 24	12.9
Dec 24	13.27
Dec 24	13.27
Dec 24	13.75
Nov 24	13.72
Nov 24	13.23
Nov 24	12.83
Nov 24	14.97
Nov 24	14.71
Oct 24	15.44

EV/EBITDA

DUL.DE EV/EBITDA by year
Period	EV/EBITDA
Sep 26	32.53
Sep 26	33.95
Sep 26	36.36
Aug 26	32.17
Aug 26	32.05
Aug 26	30.93
Aug 26	29.61
Jul 26	27.64
Jul 26	37.18
Jul 26	36.7
Jul 26	41.15
Jul 26	43.63
Jun 26	61.57
Jun 26	58.41
Jun 26	59.74
Jun 26	63.75
May 26	63.39
May 26	62.77
May 26	60.72
May 26	62.44
Apr 26	65.12
Apr 26	64.4
Apr 26	65.25
Apr 26	68.07
Apr 26	67.33
Mar 26	268.44
Mar 26	265.65
Mar 26	266.93
Mar 26	272.87
Feb 26	282.94
Feb 26	286.39
Feb 26	266.17
Feb 26	278.88
Jan 26	287.85
Jan 26	305.3
Jan 26	304.12
Jan 26	337.95
Jan 26	338.11
Dec 24	287.75
Dec 24	295.92
Dec 24	295.88
Dec 24	306.56
Nov 24	305.99
Nov 24	295.05
Nov 24	286.17
Nov 24	333.77
Nov 24	328.08
Oct 24	344.26
Oct 24	358.27
Oct 24	343.17
Oct 24	321.11

Price/Operating Cashflow

DUL.DE Price/Operating Cashflow by year
Period	Price/Operating Cashflow
Sep 26	44.59
Sep 26	46.43
Sep 26	49.56
Aug 26	44.13
Aug 26	43.97
Aug 26	42.51
Aug 26	40.81
Jul 26	38.25
Jul 26	50.61
Jul 26	49.99
Jul 26	55.76
Jul 26	58.98
Jun 26	73.56
Jun 26	69.76
Jun 26	71.35
Jun 26	76.19
May 26	75.75
May 26	75.01
May 26	72.54
May 26	74.61
Apr 26	77.84
Apr 26	76.97
Apr 26	78
Apr 26	81.38
Apr 26	80.49
Mar 26	156.29
Mar 26	154.66
Mar 26	155.41
Mar 26	158.87
Feb 26	164.74
Feb 26	166.75
Feb 26	154.96
Feb 26	162.37
Jan 26	167.6
Jan 26	177.77
Jan 26	177.08
Jan 26	196.8
Jan 26	196.9
Mar 25	608.75
Mar 25	639.88
Mar 25	548.17
Mar 25	556.75
Feb 25	558.42
Feb 25	566.18
Feb 25	577.3
Feb 25	626.39
Jan 25	620.45
Jan 25	630.91
Jan 25	558.56
Jan 25	536.56
Jan 25	529.83
Dec 24	81.24
Dec 24	83.56
Dec 24	83.55
Dec 24	86.57
Nov 24	86.41
Nov 24	83.31
Nov 24	80.79
Nov 24	94.27
Nov 24	92.66
Oct 24	97.24
Oct 24	101.21
Oct 24	96.93
Oct 24	90.69
Sep 24	183.13
Sep 24	183.63
Sep 24	176.65
Sep 24	164.99
Aug 24	172.81
Aug 24	181.57
Aug 24	177.87
Aug 24	178.93
Aug 24	181.2
Jul 24	156.99
Jul 24	159.48
Jul 24	175.13
Jul 24	167.42
Jun 24	294.04
Jun 24	199.95
Jun 24	193.36
Jun 24	183.31
May 24	180.98
May 24	177.82
May 24	179.89
May 24	181.51
May 24	184.36
Apr 24	174.58
Apr 24	173.86
Apr 24	179.97
Apr 24	185.9
Mar 24	9766.09
Mar 24	9546.1
Mar 24	9703.89
Mar 24	9758.46
Mar 24	9953.67
Feb 24	10202.74
Feb 24	9588.4
Feb 24	11095.52
Feb 24	11227.82
Jan 24	11718.43

Price to Book

DUL.DE Price to Book by year
Period	Price to Book
Sep 26	29.56
Sep 26	30.78
Sep 26	32.85
Aug 26	29.25
Aug 26	29.15
Aug 26	28.18
Aug 26	27.05
Jul 26	25.36
Jul 26	33.55
Jul 26	33.14
Jul 26	36.97
Jul 26	39.1
Jun 26	48.85
Jun 26	46.33
Jun 26	47.38
Jun 26	50.59
May 26	50.3
May 26	49.81
May 26	48.17
May 26	49.54
Apr 26	51.69
Apr 26	51.11
Apr 26	51.79
Apr 26	54.04
Apr 26	53.45
Mar 26	177.98
Mar 26	176.13
Mar 26	176.98
Mar 26	180.92
Feb 26	187.6
Feb 26	189.89
Feb 26	176.47
Feb 26	184.91
Jan 26	190.86
Jan 26	202.45
Jan 26	201.66
Jan 26	224.12
Jan 26	224.23
Dec 25	208.57
Dec 25	210.61
Dec 25	207.67
Dec 25	240.78
Nov 25	237.73
Nov 25	228.28
Nov 25	236.04
Nov 25	231.41
Oct 25	240.02
Oct 25	242.12
Oct 25	250.05
Oct 25	241.09
Oct 25	240.14
Sep 25	502.73
Sep 25	508.78
Sep 25	524.99
Sep 25	509.35
Aug 25	502.15
Aug 25	512.29
Aug 25	503.23
Aug 25	490.98
Aug 25	449.01
Jul 25	369.41
Jul 25	358.44
Jul 25	353.08
Jul 25	370.17
Jun 25	617.92
Jun 25	596.94
Jun 25	591.94
Jun 25	580.33
May 25	585.74
May 25	556.26
May 25	549.05
May 25	483.9
May 25	500.23
Apr 25	482.95
Apr 25	449.35
Apr 25	459.65
Apr 25	456.4
Mar 25	1064.09
Mar 25	1118.52
Mar 25	958.21
Mar 25	973.21
Feb 25	976.12
Feb 25	989.68
Feb 25	1009.12
Feb 25	1094.93
Jan 25	1084.55
Jan 25	1102.83
Jan 25	976.37
Jan 25	937.91
Jan 25	926.14
Dec 22	162.76
Dec 22	162.89
Dec 22	160.71
Dec 22	160.27
Nov 22	146.02
Nov 22	149.06
Nov 22	147.58
Nov 22	142.14
Oct 22	140.35
Oct 22	136.31

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Alnylam Pharmaceuticals, Inc.

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