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Castle Biosciences, Inc.

$32.33 -$6.21 (-16.11%)
NASDAQ · 11 Sep 2026 20:00 UTC
Previous Close
$32.32
Day Range
$31.71$32.94
Year Range
$17.72$44.28
Market Cap
987.67M
AVG Volume
420.02K
Trailing/Forward PE
-49.02/-
PEG ratio
2.2
Dividend Yield
-
Next Earnings Date
2026-11-02
Primary Exchange
NASDAQUS
Revenue (USD)
0100M200M300M400M20182019202020212022202320242025
CSTL Revenue (USD) by year
PeriodRevenue (USD)
2025344.23M
2024332.07M
2023219.79M
2022137.04M
202194.08M
202062.65M
201951.87M
201822.79M
Net Income (USD)
-75M-50M-25M025M20182019202020212022202320242025
CSTL Net Income (USD) by year
PeriodNet Income (USD)
2025-24.16M
202418.25M
2023-57.47M
2022-67.14M
2021-31.29M
2020-10.28M
20195.28M
2018-6.37M
Operating Income (USD)
-100M-50M050M20182019202020212022202320242025
CSTL Operating Income (USD) by year
PeriodOperating Income (USD)
2025-42.81M
20248.67M
2023-67.98M
2022-93.25M
2021-40.08M
2020-6.54M
20197.33M
2018-3.84M
EBITDA (USD)
-75M-50M-25M025M50M20182019202020212022202320242025
CSTL EBITDA (USD) by year
PeriodEBITDA (USD)
202511.34M
202438.14M
2023-45.02M
2022-58.34M
2021-36.6M
2020-7.09M
201910.28M
2018-3.76M
Cash Flows (USD)
-50M-25M025M50M20182019202020212022202320242025
CSTL Cash Flows (USD) by year
PeriodCash Flows (USD)
202528.33M
202436.54M
2023-19.25M
2022-47.29M
2021-22.47M
20205.11M
20196.08M
2018-12.57M
EPS (USD)
-3-2-10120182019202020212022202320242025
CSTL EPS (USD) by year
PeriodEPS (USD)
2025-0.85
20240.62
2023-2.16
2022-2.58
2021-1.24
2020-0.51
2019-0.05
2018-0.6
Expenses (USD)
0100M200M300M400MR&DSG&ACapex20182019202020212022202320242025
CSTL Expenses (USD) by year
PeriodExpenses (USD)
2025317.19M
2024280.32M
2023247.39M
2022193.54M
2021119.87M
202066.14M
201938.16M
201821.6M
Cash & Debt (USD)
0200M400M600MCashLong Term DebtShort Term Debt20182019202020212022202320242025
CSTL Cash & Debt (USD) by year
PeriodCash & Debt (USD)
2025299.5M
2024293.13M
2023243.1M
2022258.62M
2021329.63M
2020409.85M
201998.84M
20184.48M
Debt ratios
02.557.51020212022202320242025
CSTL Debt ratios by year
PeriodDebt ratios
20254.87
20242.62
20231.55
20222.67
20218.64
Margins
0%25%50%75%100%20182019202020212022202320242025
CSTL Margins by year
PeriodMargins
202579.37%
202481.87%
202379.53%
202276.64%
202183.18%
202084.54%
201985.91%
201876.75%
Return on Capital
-25%0%25%50%75%20182019202020212022202320242025
CSTL Return on Capital by year
PeriodReturn on Capital
2025-5.13%
20244%
2023-14.69%
2022-16.82%
2021-7.6%
2020-2.47%
20196.2%
201863.23%
Shares Outstanding
010M20M30M20182019202020212022202320242025
CSTL Shares Outstanding by year
PeriodShares Outstanding
202529.33M
202428.13M
202327.14M
202226.4M
202125.33M
202020.83M
201917.3M
201810.65M
Book Value Per Share (USD)
-100102020182019202020212022202320242025
CSTL Book Value Per Share (USD) by year
PeriodBook Value Per Share (USD)
202516.05
202416.21
202314.41
202215.12
202116.26
202019.95
20194.92
2018-0.95
Total Assets (USD)
0200M400M600M20182019202020212022202320242025
CSTL Total Assets (USD) by year
PeriodTotal Assets (USD)
2025578.56M
2024531.24M
2023453.34M
2022447.33M
2021462.57M
2020439.33M
2019119.75M
201822.4M
Employee Count
02505007501K2019202020212022202320242025
CSTL Employee Count by year
PeriodEmployee Count
2025883
2024761
2023610
2022542
2021342
2020199
2019133
PE Ratio
050100150200med 92.82Dec 19Mar 20Jun 20Aug 20Nov 24Feb 25May 25
CSTL PE Ratio by year
PeriodPE Ratio
May 2529.83
Apr 2531.8
Apr 2533.16
Apr 2530.37
Apr 2528.63
Mar 2530.74
Mar 2531.63
Mar 2529.74
Mar 2531.16
Feb 2533.42
Feb 25118
Feb 25125.2
Feb 25126.48
Jan 25129.55
Jan 25121.17
Jan 25114.29
Jan 25138.63
Jan 25131.11
Dec 24122.95
Dec 24126.16
Dec 24132.3
Dec 24142.93
Nov 24138.76
Nov 24136.61
Nov 24128.77
Nov 24152.56
Nov 20127.78
Oct 20114.76
Oct 20128.13
Oct 20123.51
Oct 20135.6
Oct 20127.12
Sep 20122.64
Sep 20126.15
Sep 20120.12
Sep 20118.76
Aug 20112.61
Aug 20113.15
Aug 20102.13
Aug 20100.78
Jul 2093.36
Jul 2094.13
Jul 20103.65
Jul 20100.66
Jul 2092.76
Jun 2084.61
Jun 20102.18
Jun 2089.26
Jun 2090.87
May 2092.66
May 2091.45
May 2090.3
May 20103.24
May 2092.88
Apr 2096.52
Apr 2097.01
Apr 2091.93
Apr 2089.64
Mar 2092.65
Mar 2092.1
Mar 2078.89
Mar 2057.92
Feb 2053.87
Feb 2058.31
Feb 2057.22
Feb 2055.74
Jan 2055.49
Jan 2053.78
Jan 2058.28
Jan 2060.47
Jan 2059.41
Dec 1961.16
Dec 1952.75
Dec 1953.08
Dec 1954.55
Nov 1948.45
Nov 1948.2
Nov 1951.75
Free Cash Flow Yield
-5%0%5%10%med 4.1%Dec 24Apr 25Jul 25Oct 25Feb 26May 26Sep 26
CSTL Free Cash Flow Yield by year
PeriodFree Cash Flow Yield
Sep 26-0.05%
Sep 26-0.05%
Aug 26-0.05%
Aug 26-0.05%
Aug 26-0.05%
Aug 26-0.05%
Jul 26-0.06%
Jul 260.61%
Jul 260.63%
Jul 260.64%
Jul 260.63%
Jun 260.62%
Jun 260.72%
Jun 260.73%
Jun 260.72%
May 260.72%
May 260.75%
May 260.79%
May 260.76%
May 263.89%
Apr 263.95%
Apr 263.85%
Apr 264.17%
Apr 263.89%
Mar 264.1%
Mar 263.86%
Mar 263.78%
Mar 263.56%
Feb 263.27%
Feb 263.47%
Feb 263.06%
Feb 263.09%
Jan 262.57%
Jan 262.4%
Jan 262.53%
Jan 262.58%
Jan 262.63%
Dec 252.57%
Dec 252.57%
Dec 252.62%
Dec 252.62%
Nov 252.54%
Nov 252.67%
Nov 253.03%
Nov 253.07%
Oct 254.68%
Oct 254.87%
Oct 255.4%
Oct 255.18%
Oct 255.26%
Sep 255.26%
Sep 254.89%
Sep 255.58%
Sep 255.07%
Aug 254.98%
Aug 255.73%
Aug 255.95%
Aug 256.17%
Aug 259.96%
Jul 259.08%
Jul 258.82%
Jul 257.42%
Jul 257.19%
Jun 257.17%
Jun 257.88%
Jun 257.78%
Jun 258.29%
May 259.14%
May 259.06%
May 258.71%
May 258.69%
May 256.71%
Apr 256.3%
Apr 256.04%
Apr 256.59%
Apr 257%
Mar 256.52%
Mar 256.33%
Mar 256.73%
Mar 256.43%
Feb 255.99%
Feb 254.82%
Feb 254.54%
Feb 254.49%
Jan 254.39%
Jan 254.69%
Jan 254.97%
Jan 254.1%
Jan 254.34%
Dec 244.62%
Dec 244.51%
Dec 244.3%
Dec 243.98%
Nov 244.1%
Nov 244.16%
Nov 244.41%
Nov 243.73%
Nov 242.2%
Oct 242.32%
Oct 242.23%
Price to Sales
11.522.533.5med 2.13Dec 24Apr 25Jul 25Oct 25Feb 26May 26Sep 26
CSTL Price to Sales by year
PeriodPrice to Sales
Sep 262.75
Sep 262.8
Aug 262.85
Aug 262.91
Aug 262.52
Aug 262.73
Jul 262.38
Jul 262.17
Jul 262.12
Jul 262.09
Jul 262.12
Jun 262.14
Jun 261.86
Jun 261.82
Jun 261.85
May 261.85
May 261.77
May 261.68
May 261.74
May 262.11
Apr 262.08
Apr 262.13
Apr 261.97
Apr 262.12
Mar 262.01
Mar 262.13
Mar 262.18
Mar 262.31
Feb 262.52
Feb 262.13
Feb 262.42
Feb 262.39
Jan 262.87
Jan 263.08
Jan 262.92
Jan 262.87
Jan 262.81
Dec 252.87
Dec 252.88
Dec 252.82
Dec 252.82
Nov 252.91
Nov 252.76
Nov 252.44
Nov 252.41
Oct 252.13
Oct 252.05
Oct 251.85
Oct 251.93
Oct 251.9
Sep 251.9
Sep 252.04
Sep 251.79
Sep 251.97
Aug 252
Aug 251.74
Aug 251.68
Aug 251.62
Aug 251.21
Jul 251.32
Jul 251.36
Jul 251.62
Jul 251.67
Jun 251.68
Jun 251.53
Jun 251.55
Jun 251.45
May 251.32
May 251.33
May 251.38
May 251.38
May 251.64
Apr 251.75
Apr 251.82
Apr 251.67
Apr 251.57
Mar 251.69
Mar 251.74
Mar 251.63
Mar 251.71
Feb 251.84
Feb 252.3
Feb 252.44
Feb 252.46
Jan 252.52
Jan 252.36
Jan 252.23
Jan 252.7
Jan 252.55
Dec 242.39
Dec 242.46
Dec 242.58
Dec 242.78
Nov 242.7
Nov 242.66
Nov 242.51
Nov 242.97
Nov 243.19
Oct 243.02
Oct 243.14
EV/EBITDA
050001000015000med 23.51Aug 24Nov 24Mar 25Jun 25Oct 25Jan 26May 26
CSTL EV/EBITDA by year
PeriodEV/EBITDA
May 2641.01
Apr 2640.1
Apr 2641.63
Apr 2636.66
Apr 2641.09
Mar 2637.7
Mar 2641.5
Mar 2642.95
Mar 2646.98
Feb 2653.32
Feb 2620.05
Feb 2624.17
Feb 2623.75
Jan 2630.68
Jan 2633.65
Jan 2631.33
Jan 2630.63
Jan 2629.79
Dec 2530.69
Dec 2530.73
Dec 2529.89
Dec 2529.9
Nov 2531.26
Nov 2529.1
Nov 2524.48
Nov 2524.05
Oct 2515.31
Oct 2514.43
Oct 2512.33
Oct 2513.16
Oct 2512.84
Sep 2512.84
Sep 2514.34
Sep 2511.69
Sep 2513.59
Aug 2513.99
Aug 2511.18
Aug 2510.51
Aug 259.86
Aug 254.16
Jul 255.16
Jul 255.49
Jul 257.68
Jul 258.13
Jun 258.16
Jun 256.88
Jun 257.04
Jun 256.23
May 255.09
May 255.18
May 255.64
May 255.67
May 257.27
Apr 258.22
Apr 258.87
Apr 257.53
Apr 256.7
Mar 257.71
Mar 258.14
Mar 257.23
Mar 257.91
Feb 258.99
Feb 2518.5
Feb 2520.24
Feb 2520.55
Jan 2521.29
Jan 2519.26
Jan 2517.6
Jan 2523.49
Jan 2521.67
Dec 2419.69
Dec 2420.47
Dec 2421.96
Dec 2424.53
Nov 2423.52
Nov 2423
Nov 2421.1
Nov 2426.87
Nov 2472.88
Oct 2467.62
Oct 2471.38
Oct 2467.45
Oct 2461.66
Sep 2457.25
Sep 2467.92
Sep 2467.06
Sep 2461.57
Aug 2462.6
Aug 2462.31
Aug 2454.68
Aug 2454.21
Mar 218196.94
Feb 219152.2
Feb 2111124.59
Feb 2111770.4
Feb 2111400.41
Jan 217907.68
Jan 219567.93
Jan 218891.18
Jan 219627.13
Price/Operating Cashflow
510152025med 12.41Dec 24Apr 25Jul 25Oct 25Feb 26May 26Sep 26
CSTL Price/Operating Cashflow by year
PeriodPrice/Operating Cashflow
Sep 2623.05
Sep 2623.47
Aug 2623.89
Aug 2624.39
Aug 2621.12
Aug 2622.84
Jul 2619.96
Jul 2615.29
Jul 2614.96
Jul 2614.69
Jul 2614.93
Jun 2615.05
Jun 2613.08
Jun 2612.82
Jun 2613.01
May 2613.06
May 2612.48
May 2611.85
May 2612.28
May 2611.31
Apr 2611.15
Apr 2611.42
Apr 2610.54
Apr 2611.32
Mar 2610.73
Mar 2611.4
Mar 2611.65
Mar 2612.36
Feb 2613.48
Feb 2611.84
Feb 2613.44
Feb 2613.28
Jan 2615.97
Jan 2617.13
Jan 2616.22
Jan 2615.95
Jan 2615.63
Dec 2515.98
Dec 2515.99
Dec 2515.66
Dec 2515.67
Nov 2516.2
Nov 2515.36
Nov 2513.56
Nov 2513.4
Oct 2511.8
Oct 2511.34
Oct 2510.24
Oct 2510.68
Oct 2510.51
Sep 2510.51
Sep 2511.29
Sep 259.91
Sep 2510.9
Aug 2511.11
Aug 259.64
Aug 259.3
Aug 258.96
Aug 256.38
Jul 257
Jul 257.21
Jul 258.57
Jul 258.84
Jun 258.87
Jun 258.07
Jun 258.17
Jun 257.67
May 256.96
May 257.01
May 257.3
May 257.32
May 258.39
Apr 258.95
Apr 259.33
Apr 258.54
Apr 258.05
Mar 258.65
Mar 258.9
Mar 258.36
Mar 258.76
Feb 259.4
Feb 2512.13
Feb 2512.87
Feb 2513
Jan 2513.32
Jan 2512.46
Jan 2511.75
Jan 2514.25
Jan 2513.48
Dec 2412.64
Dec 2412.97
Dec 2413.6
Dec 2414.7
Nov 2414.27
Nov 2414.05
Nov 2413.24
Nov 2415.68
Nov 2422.48
Oct 2421.28
Oct 2422.14
Price to Book
0.511.522.5med 1.56Dec 24Apr 25Jul 25Oct 25Feb 26May 26Sep 26
CSTL Price to Book by year
PeriodPrice to Book
Sep 262.09
Sep 262.13
Aug 262.17
Aug 262.21
Aug 261.92
Aug 262.07
Jul 261.81
Jul 261.6
Jul 261.57
Jul 261.54
Jul 261.56
Jun 261.57
Jun 261.37
Jun 261.34
Jun 261.36
May 261.37
May 261.31
May 261.24
May 261.28
May 261.55
Apr 261.52
Apr 261.56
Apr 261.44
Apr 261.55
Mar 261.47
Mar 261.56
Mar 261.59
Mar 261.69
Feb 261.84
Feb 261.57
Feb 261.78
Feb 261.76
Jan 262.11
Jan 262.27
Jan 262.15
Jan 262.11
Jan 262.07
Dec 252.11
Dec 252.12
Dec 252.07
Dec 252.07
Nov 252.14
Nov 252.03
Nov 251.79
Nov 251.77
Oct 251.62
Oct 251.56
Oct 251.41
Oct 251.47
Oct 251.44
Sep 251.44
Sep 251.55
Sep 251.36
Sep 251.5
Aug 251.52
Aug 251.32
Aug 251.28
Aug 251.23
Aug 250.95
Jul 251.04
Jul 251.07
Jul 251.28
Jul 251.32
Jun 251.32
Jun 251.2
Jun 251.22
Jun 251.14
May 251.04
May 251.05
May 251.09
May 251.09
May 251.19
Apr 251.27
Apr 251.33
Apr 251.22
Apr 251.15
Mar 251.23
Mar 251.27
Mar 251.19
Mar 251.25
Feb 251.34
Feb 251.63
Feb 251.72
Feb 251.74
Jan 251.78
Jan 251.67
Jan 251.57
Jan 251.91
Jan 251.81
Dec 241.69
Dec 241.74
Dec 241.82
Dec 241.97
Nov 241.91
Nov 241.88
Nov 241.77
Nov 242.1
Nov 242.16
Oct 242.05
Oct 242.13
Castle Biosciences, Inc.
CSTL
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News: CSTL

JAAD Publication Shows Improved Performance of DecisionDx®-SCC

prnewswire.com · 9 Sep 2026

JAAD Publication Shows Improved Performance of DecisionDx®-SCC

DecisionDx-SCC shows enhanced performance with the integration of select clinicopathologic risk factors, providing a more precise result to support risk-aligned patient management DecisionDx-SCC's Class 1A (low risk) result demonstrated a 97.3% negative predictive value, supporting confidence in de-escalation decisions, while its Class 2B (highest risk) result identified patients most likely to benefit from adjuvant radiation therapy FRIENDSWOOD, Texas, Sept. 9, 2026 /PRNewswire/ -- Castle Biosciences, Inc. (Nasdaq: CSTL), a company improving health through innovative tests that guide patient care, today announced the publication of a multi-center study in the Journal of the American Academy of Dermatology (JAAD) validating the integrated DecisionDx-SCC test result (i40-GEP) for patients with high-risk cutaneous squamous cell carcinoma (SCC).1 DecisionDx-SCC analyzes 40 genes to provide results related to prognosis and response to adjuvant radiation therapy (ART) based on an individual patient's tumor biology.

SciBase receives additional order from Castle Biosciences, advancing the collaboration

prnewswire.com · 8 Sep 2026

SciBase receives additional order from Castle Biosciences, advancing the collaboration

STOCKHOLM, Sept. 8, 2026 /PRNewswire/ -- SciBase Holding AB ("SciBase") (STO: SCIB), a leader in AI-based devices for detection and prevention in dermatology, today announces that it has received an additional order for an acceleration of the current, ongoing clinical study and preparations for a second clinical study under the collaboration with Castle Biosciences.

Castle Biosciences, Inc. (CSTL) Is Up 15.46% in One Week: What You Should Know

zacks.com · 28 Aug 2026

Castle Biosciences, Inc. (CSTL) Is Up 15.46% in One Week: What You Should Know

Does Castle Biosciences, Inc. (CSTL) have what it takes to be a top stock pick for momentum investors? Let's find out.

Does Castle Biosciences (CSTL) Have the Potential to Rally 31.46% as Wall Street Analysts Expect?

zacks.com · 25 Aug 2026

Does Castle Biosciences (CSTL) Have the Potential to Rally 31.46% as Wall Street Analysts Expect?

The consensus price target hints at a 31.5% upside potential for Castle Biosciences (CSTL). While empirical research shows that this sought-after metric is hardly effective, an upward trend in earnings estimate revisions could mean that the stock will witness an upside in the near term.

Castle Biosciences to Participate in Upcoming Investor Conferences

prnewswire.com · 20 Aug 2026

Castle Biosciences to Participate in Upcoming Investor Conferences

FRIENDSWOOD, Texas, Aug. 20, 2026 /PRNewswire/ -- Castle Biosciences, Inc. (Nasdaq: CSTL), a company improving health through innovative tests that guide patient care, today announced that its executive management is scheduled to present a company overview at Baird's 2026 Global Healthcare Conference on Tuesday, Sept. 15, 2026, at 10:50 a.m.

Castle Biosciences Approved for Dual Listing on Nasdaq Texas

prnewswire.com · 17 Aug 2026

Castle Biosciences Approved for Dual Listing on Nasdaq Texas

FRIENDSWOOD, Texas, Aug. 17, 2026 /PRNewswire/ -- Castle Biosciences, Inc. (Nasdaq: CSTL), a company improving health through innovative tests that guide patient care, today announced that it has been approved to have its common stock dually listed on Nasdaq Texas, a new exchange headquartered in Dallas. Castle will maintain its primary listing on The Nasdaq Global Market, and its common stock is expected to begin listing on Nasdaq Texas today under its existing ticker symbol, "CSTL.

Castle Biosciences Raises Outlook as Melanoma, TissueCypher Tests Gain Traction

marketbeat.com · 13 Aug 2026

Castle Biosciences Raises Outlook as Melanoma, TissueCypher Tests Gain Traction

Castle Biosciences NASDAQ: CSTL reported continued momentum in its core diagnostic franchises during the second quarter, prompting the company to raise its outlook by more than the amount of its reported beat, according to CFO Frank Stokes.

Comparing Gaxos.ai (NASDAQ:GXAI) and Castle Biosciences (NASDAQ:CSTL)

defenseworld.net · 4 Aug 2026

Comparing Gaxos.ai (NASDAQ:GXAI) and Castle Biosciences (NASDAQ:CSTL)

Castle Biosciences (NASDAQ: CSTL - Get Free Report) and Gaxos.ai (NASDAQ: GXAI - Get Free Report) are both small-cap healthcare companies, but which is the superior stock? We will compare the two businesses based on the strength of their risk, dividends, institutional ownership, valuation, analyst recommendations, profitability and earnings. Earnings and Valuation This table compares Castle Biosciences

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