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Axsome Therapeutics, Inc.

$220.75 +$42.06 (+23.54%)
NASDAQ · 11 Sep 2026 20:00 UTC
Previous Close
$211.12
Day Range
$212.44$229
Year Range
$112.9$260.19
Market Cap
11.36B
AVG Volume
791.49K
Trailing/Forward PE
-58.87/47.39
PEG ratio
0.21
Dividend Yield
-
Next Earnings Date
2026-11-02
Primary Exchange
NASDAQUS
Revenue (USD)
0200M400M600M800M2016201720182019202020212022202320242025
AXSM Revenue (USD) by year
PeriodRevenue (USD)
2025638.5M
2024385.69M
2023270.6M
202250.04M
20210
20200
20190
20180
20170
20160
Net Income (USD)
-300M-200M-100M02016201720182019202020212022202320242025
AXSM Net Income (USD) by year
PeriodNet Income (USD)
2025-183.17M
2024-287.22M
2023-239.24M
2022-187.13M
2021-130.4M
2020-102.9M
2019-68.35M
2018-30.97M
2017-28.94M
2016-27.2M
Operating Income (USD)
-300M-200M-100M02016201720182019202020212022202320242025
AXSM Operating Income (USD) by year
PeriodOperating Income (USD)
2025-169.24M
2024-280.56M
2023-231.82M
2022-179.8M
2021-124.71M
2020-99.14M
2019-67.25M
2018-32.85M
2017-27.16M
2016-27.54M
EBITDA (USD)
-300M-200M-100M02016201720182019202020212022202320242025
AXSM EBITDA (USD) by year
PeriodEBITDA (USD)
2025-166.48M
2024-272.6M
2023-224.53M
2022-175.4M
2021-123.55M
2020-100.26M
2019-67.07M
2018-29.8M
2017-27.56M
2016-27.05M
Cash Flows (USD)
-150M-100M-50M02016201720182019202020212022202320242025
AXSM Cash Flows (USD) by year
PeriodCash Flows (USD)
2025-93.89M
2024-128.44M
2023-145.66M
2022-117.21M
2021-108.23M
2020-78.5M
2019-46.39M
2018-30.05M
2017-26.48M
2016-21.39M
EPS (USD)
-6-4-202016201720182019202020212022202320242025
AXSM EPS (USD) by year
PeriodEPS (USD)
2025-3.69
2024-5.99
2023-5.2
2022-4.57
2021-3.47
2020-2.76
2019-2
2018-1.14
2017-1.29
2016-1.43
Expenses (USD)
0200M400M600M800MR&DSG&ACapex2016201720182019202020212022202320242025
AXSM Expenses (USD) by year
PeriodExpenses (USD)
2025754.36M
2024598.47M
2023421.65M
2022217.9M
2021124.71M
202099.19M
201967.26M
201832.85M
201727.17M
201627.65M
Cash & Debt (USD)
0100M200M300M400MCashLong Term DebtShort Term Debt2016201720182019202020212022202320242025
AXSM Cash & Debt (USD) by year
PeriodCash & Debt (USD)
2025322.93M
2024315.35M
2023386.19M
2022200.84M
202186.47M
2020183.88M
2019219.97M
201813.97M
201734.02M
201636.62M
Debt ratios
00.511.520182019202020212022202320242025
AXSM Debt ratios by year
PeriodDebt ratios
20250.1
20240.15
20230.32
20220.23
20210.11
20200.6
20191.32
20180.08
Margins
0%25%50%75%100%2022202320242025
AXSM Margins by year
PeriodMargins
202592.56%
202491.37%
202390.37%
202289.61%
Return on Capital
-4000%-3000%-2000%-1000%0%2016201720182019202020212022202320242025
AXSM Return on Capital by year
PeriodReturn on Capital
2025-207.46%
2024-503.76%
2023-125.27%
2022-170.81%
2021-834.29%
2020-90.43%
2019-38.24%
2018-3301.5%
2017-173.14%
2016-126.1%
Shares Outstanding
020M40M60M2016201720182019202020212022202320242025
AXSM Shares Outstanding by year
PeriodShares Outstanding
202550.63M
202448.54M
202347.33M
202243.45M
202137.76M
202037.35M
201934.76M
201829.87M
201724.23M
201619.15M
Book Value Per Share (USD)
02462016201720182019202020212022202320242025
AXSM Book Value Per Share (USD) by year
PeriodBook Value Per Share (USD)
20251.74
20241.17
20234.04
20222.52
20210.41
20203.05
20195.14
20180.03
20170.69
20161.13
Total Assets (USD)
0200M400M600M800M2016201720182019202020212022202320242025
AXSM Total Assets (USD) by year
PeriodTotal Assets (USD)
2025689.8M
2024568.5M
2023588.24M
2022331.48M
202187.79M
2020186.13M
2019220.55M
201815.38M
201735.56M
201638.21M
Employee Count
02505007501K2016201720182019202020212022202320242025
AXSM Employee Count by year
PeriodEmployee Count
2025925
2024683
2023545
2022383
2021108
202060
201945
201829
201725
201622
Free Cash Flow Yield
-4%-3%-2%-1%0%med -1.98%Dec 24Apr 25Jul 25Oct 25Feb 26May 26Sep 26
AXSM Free Cash Flow Yield by year
PeriodFree Cash Flow Yield
Sep 26-0.63%
Sep 26-0.67%
Aug 26-0.7%
Aug 26-0.67%
Aug 26-0.65%
Aug 26-0.65%
Jul 26-0.64%
Jul 26-0.58%
Jul 26-0.6%
Jul 26-0.59%
Jul 26-0.57%
Jun 26-0.57%
Jun 26-0.55%
Jun 26-0.54%
Jun 26-0.6%
May 26-0.59%
May 26-0.59%
May 26-0.61%
May 26-0.64%
May 26-0.9%
Apr 26-1%
Apr 26-0.98%
Apr 26-1.04%
Apr 26-1.1%
Mar 26-1.19%
Mar 26-1.18%
Mar 26-1.19%
Mar 26-1.14%
Feb 26-1.13%
Feb 26-1.1%
Feb 26-1.12%
Feb 26-1.11%
Jan 26-1.1%
Jan 26-1.09%
Jan 26-1.14%
Jan 26-1.2%
Jan 26-1.13%
Dec 25-1.33%
Dec 25-1.33%
Dec 25-1.37%
Dec 25-1.36%
Nov 25-1.34%
Nov 25-1.36%
Nov 25-1.45%
Nov 25-1.47%
Oct 25-1.81%
Oct 25-1.89%
Oct 25-1.91%
Oct 25-2.01%
Oct 25-2.03%
Sep 25-2.09%
Sep 25-2.11%
Sep 25-2.06%
Sep 25-1.95%
Aug 25-2.02%
Aug 25-2.06%
Aug 25-2.24%
Aug 25-2.33%
Aug 25-2.36%
Jul 25-2.41%
Jul 25-2.17%
Jul 25-2.23%
Jul 25-2.3%
Jun 25-2.35%
Jun 25-2.41%
Jun 25-2.33%
Jun 25-2.17%
May 25-2.31%
May 25-2.31%
May 25-2.26%
May 25-2.25%
May 25-2.36%
Apr 25-2.49%
Apr 25-2.53%
Apr 25-2.7%
Apr 25-2.68%
Mar 25-2.23%
Mar 25-2.09%
Mar 25-2.17%
Mar 25-2.17%
Feb 25-2.07%
Feb 25-1.92%
Feb 25-2.1%
Feb 25-2.6%
Jan 25-2.59%
Jan 25-2.67%
Jan 25-3%
Jan 25-3.44%
Jan 25-3.19%
Dec 24-3.18%
Dec 24-3.04%
Dec 24-3.06%
Dec 24-2.75%
Nov 24-2.8%
Nov 24-2.79%
Nov 24-2.96%
Nov 24-3.92%
Nov 24-3.98%
Oct 24-3.93%
Oct 24-3.78%
Price to Sales
1012.51517.520med 13.53Dec 24Apr 25Jul 25Oct 25Feb 26May 26Sep 26
AXSM Price to Sales by year
PeriodPrice to Sales
Sep 2614.64
Sep 2613.71
Aug 2613.2
Aug 2613.78
Aug 2614.17
Aug 2615.38
Jul 2615.76
Jul 2617.42
Jul 2616.63
Jul 2616.9
Jul 2617.66
Jun 2617.47
Jun 2618.11
Jun 2618.45
Jun 2616.79
May 2616.95
May 2617.06
May 2616.46
May 2615.71
May 2616.38
Apr 2614.75
Apr 2614.99
Apr 2614.12
Apr 2613.36
Mar 2612.4
Mar 2612.44
Mar 2612.38
Mar 2612.87
Feb 2613
Feb 2616.37
Feb 2616.15
Feb 2616.27
Jan 2616.42
Jan 2616.57
Jan 2615.8
Jan 2615.1
Jan 2615.93
Dec 2513.55
Dec 2513.6
Dec 2513.21
Dec 2513.3
Nov 2513.5
Nov 2513.32
Nov 2512.45
Nov 2512.31
Oct 2513.48
Oct 2512.94
Oct 2512.78
Oct 2512.16
Oct 2512.02
Sep 2511.66
Sep 2511.58
Sep 2511.83
Sep 2512.5
Aug 2512.11
Aug 2511.84
Aug 2510.91
Aug 2510.47
Aug 2511.65
Jul 2511.4
Jul 2512.63
Jul 2512.32
Jul 2511.92
Jun 2511.69
Jun 2511.39
Jun 2511.77
Jun 2512.66
May 2511.89
May 2511.88
May 2512.16
May 2512.19
May 2514.12
Apr 2513.37
Apr 2513.15
Apr 2512.34
Apr 2512.44
Mar 2514.92
Mar 2515.96
Mar 2515.34
Mar 2515.38
Feb 2516.05
Feb 2517.34
Feb 2518.65
Feb 2515.04
Jan 2515.14
Jan 2514.67
Jan 2513.08
Jan 2511.39
Jan 2512.3
Dec 2412.33
Dec 2412.91
Dec 2412.82
Dec 2414.24
Nov 2413.97
Nov 2414.04
Nov 2413.25
Nov 2414.7
Nov 2414.5
Oct 2414.67
Oct 2415.24
Price to Book
050100150200250med 96.61Dec 24Apr 25Jul 25Oct 25Feb 26May 26Sep 26
AXSM Price to Book by year
PeriodPrice to Book
Sep 26136.47
Sep 26127.77
Aug 26123.04
Aug 26128.45
Aug 26132.1
Aug 26199.53
Jul 26204.46
Jul 26226.04
Jul 26215.72
Jul 26219.29
Jul 26229.14
Jun 26226.67
Jun 26234.95
Jun 26239.33
Jun 26217.9
May 26219.92
May 26221.32
May 26213.58
May 26203.89
May 26118.43
Apr 26106.64
Apr 26108.37
Apr 26102.13
Apr 2696.63
Mar 2689.66
Mar 2689.98
Mar 2689.5
Mar 2693.09
Feb 2693.98
Feb 26124.65
Feb 26122.95
Feb 26123.86
Jan 26125.01
Jan 26126.17
Jan 26120.27
Jan 26114.92
Jan 26121.24
Dec 25103.16
Dec 25103.57
Dec 25100.53
Dec 25101.24
Nov 25102.79
Nov 25101.39
Nov 2594.78
Nov 2593.73
Oct 2591.33
Oct 2587.65
Oct 2586.56
Oct 2582.35
Oct 2581.39
Sep 2579
Sep 2578.45
Sep 2580.12
Sep 2584.69
Aug 2582.06
Aug 2580.18
Aug 2573.9
Aug 2570.91
Aug 2594.63
Jul 2592.62
Jul 25102.6
Jul 25100.1
Jul 2596.85
Jun 2594.94
Jun 2592.49
Jun 2595.62
Jun 25102.79
May 2596.59
May 2596.51
May 2598.77
May 2598.98
May 2595.53
Apr 2590.48
Apr 2588.94
Apr 2583.49
Apr 2584.17
Mar 25100.92
Mar 25107.95
Mar 25103.79
Mar 25104.01
Feb 25108.59
Feb 25117.28
Feb 2567.96
Feb 2554.81
Jan 2555.17
Jan 2553.43
Jan 2547.64
Jan 2541.48
Jan 2544.8
Dec 2444.93
Dec 2447.02
Dec 2446.69
Dec 2451.87
Nov 2450.9
Nov 2451.14
Nov 2448.28
Nov 2441.66
Nov 2441.09
Oct 2441.57
Oct 2443.18
Axsome Therapeutics, Inc.
AXSM
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News: AXSM

Axsome Therapeutics vs. CRISPR Therapeutics: Which Healthcare Stock Is a Better Buy in 2026?

fool.com · 11 Sep 2026

Axsome Therapeutics vs. CRISPR Therapeutics: Which Healthcare Stock Is a Better Buy in 2026?

One company is scaling revenue rapidly but burning cash; the other is pioneering gene therapy with minimal sales and massive losses.

Axsome Therapeutics, Inc. (AXSM) Presents at 12th Annual Cantor Fitzgerald Global Healthcare Conference Transcript

seekingalpha.com · 10 Sep 2026

Axsome Therapeutics, Inc. (AXSM) Presents at 12th Annual Cantor Fitzgerald Global Healthcare Conference Transcript

Axsome Therapeutics, Inc. (AXSM) Presents at 12th Annual Cantor Fitzgerald Global Healthcare Conference Transcript

Axsome Therapeutics vs. Viking Therapeutics: Which Healthcare Stock Is a Better Buy in 2026?

fool.com · 10 Sep 2026

Axsome Therapeutics vs. Viking Therapeutics: Which Healthcare Stock Is a Better Buy in 2026?

Axsome Therapeutics has transitioned into a commercial-stage entity with rapidly growing revenue from its central nervous system treatments. Viking Therapeutics remains a clinical-stage player with significant potential in the high-demand obesity and metabolic disease markets.

Axsome Therapeutics, Inc. (AXSM) Presents at Wells Fargo 21st Annual Healthcare Conference Transcript

seekingalpha.com · 9 Sep 2026

Axsome Therapeutics, Inc. (AXSM) Presents at Wells Fargo 21st Annual Healthcare Conference Transcript

Axsome Therapeutics, Inc. (AXSM) Presents at Wells Fargo 21st Annual Healthcare Conference Transcript

Axsome (AXSM) Down 3.7% Since Last Earnings Report: Can It Rebound?

zacks.com · 9 Sep 2026

Axsome (AXSM) Down 3.7% Since Last Earnings Report: Can It Rebound?

Axsome (AXSM) reported earnings 30 days ago. What's next for the stock?

Axsome Therapeutics to Participate in Upcoming Investor Conferences

globenewswire.com · 2 Sep 2026

Axsome Therapeutics to Participate in Upcoming Investor Conferences

NEW YORK, Sept. 02, 2026 (GLOBE NEWSWIRE) -- Axsome Therapeutics, Inc. (NASDAQ: AXSM), a biopharmaceutical company leading a new era in the treatment of central nervous system (CNS) disorders, today announced that it will participate in the following upcoming investor conferences in September: Wells Fargo 21 st Annual Healthcare Conference Fireside Chat: Wednesday, September 9, 2026, at 3:45 p.m.

Axsome Begins Phase III Study on AXS-05 for Smoking Cessation

zacks.com · 1 Sep 2026

Axsome Begins Phase III Study on AXS-05 for Smoking Cessation

AXSM begins dosing in the phase III SUMMIT study investigating AXS-05 for treating smoking cessation in adults.

Axsome Therapeutics Initiates SUMMIT Phase 3 Trial of AXS-05 in Smoking Cessation

globenewswire.com · 31 Aug 2026

Axsome Therapeutics Initiates SUMMIT Phase 3 Trial of AXS-05 in Smoking Cessation

NEW YORK, Aug. 31, 2026 (GLOBE NEWSWIRE) -- Axsome Therapeutics, Inc. (NASDAQ: AXSM), a biopharmaceutical company leading a new era in the treatment of central nervous system (CNS) disorders, today announced that the first patient has been dosed in the SUMMIT Phase 3 trial of AXS-05 for smoking cessation. SUMMIT (Studying NMDA and Sigma-1 in Smoking Cessation Treatment) is a Phase 3 randomized, double-blind, active- and placebo-controlled, multicenter trial to assess the efficacy and safety of AXS-05 as a smoking cessation treatment in adults.

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