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Annovis Bio, Inc.

$1.12 -$2.53 (-69.32%)
NYSE · 11 Sep 2026 20:00 UTC
Previous Close
$1.19
Day Range
$1.11$1.23
Year Range
$1.1$5.5
Market Cap
47.65M
AVG Volume
1.01M
Trailing/Forward PE
-0.63/-
PEG ratio
0.02
Dividend Yield
-
Next Earnings Date
2026-11-11
Primary Exchange
New York Stock ExchangeUS
Net Income (USD)
-60M-40M-20M020182019202020212022202320242025
ANVS Net Income (USD) by year
PeriodNet Income (USD)
2025-28.85M
2024-24.59M
2023-56.2M
2022-25.33M
2021-14.49M
2020-5.46M
2019-991.26K
2018-714K
Operating Income (USD)
-60M-40M-20M020182019202020212022202320242025
ANVS Operating Income (USD) by year
PeriodOperating Income (USD)
2025-29.7M
2024-26.69M
2023-45.04M
2022-15M
2021-14.54M
2020-6.64M
2019-1.61M
2018-714K
EBITDA (USD)
-60M-40M-20M020M20182019202020212022202320242025
ANVS EBITDA (USD) by year
PeriodEBITDA (USD)
2025-28.85M
2024-22.72M
2023-56.2M
2022-17.55M
2021-8.57M
2020-3.66M
2019267.11K
2018-714K
Cash Flows (USD)
-40M-30M-20M-10M020182019202020212022202320242025
ANVS Cash Flows (USD) by year
PeriodCash Flows (USD)
2025-25.62M
2024-21.89M
2023-39.97M
2022-17.31M
2021-9.13M
2020-3.97M
2019-476.54K
2018-558.61K
EPS (USD)
-10-7.5-5-2.5020182019202020212022202320242025
ANVS EPS (USD) by year
PeriodEPS (USD)
2025-1.41
2024-1.99
2023-8.62
2022-3.07
2021-1.88
2020-0.84
2019-0.22
2018-0.16
Expenses (USD)
020M40M60MR&DSG&ACapex20182019202020212022202320242025
ANVS Expenses (USD) by year
PeriodExpenses (USD)
202529.7M
202426.69M
202345.04M
202225.51M
202114.54M
20206.64M
20191.61M
2018713.94K
Cash & Debt (USD)
020M40M60MCashLong Term Debt20182019202020212022202320242025
ANVS Cash & Debt (USD) by year
PeriodCash & Debt (USD)
202519.53M
202410.55M
20235.75M
202228.38M
202145.69M
20208.07M
20191.86K
201835.31K
Debt ratios
0123420212022202320242025
ANVS Debt ratios by year
PeriodDebt ratios
20250.16
20240.1
20230.07
20220.96
20213.6
Return on Capital
-500%-250%0%250%500%750%20182019202020212022202320242025
ANVS Return on Capital by year
PeriodReturn on Capital
2025-171.23%
2024-264.2%
2023725.14%
2022-89.43%
2021-32.56%
2020-72.43%
201911.56%
20189.4%
Shares Outstanding
010M20M30M20182019202020212022202320242025
ANVS Shares Outstanding by year
PeriodShares Outstanding
202524.81M
202413.79M
20239.53M
20228.16M
20218.1M
20206.79M
20194.6M
20184.4M
Book Value Per Share (USD)
-2024620182019202020212022202320242025
ANVS Book Value Per Share (USD) by year
PeriodBook Value Per Share (USD)
20250.68
20240.67
2023-0.81
20223.47
20215.49
20201.11
2019-1.86
2018-1.73
Total Assets (USD)
020M40M60M20182019202020212022202320242025
ANVS Total Assets (USD) by year
PeriodTotal Assets (USD)
202521.08M
202413.93M
202310.21M
202236.02M
202146M
20208.12M
20191.12M
201850.99K
Employee Count
024682019202020212022202320242025
ANVS Employee Count by year
PeriodEmployee Count
20258
20248
20236
20225
20213
20202
20192
Free Cash Flow Yield
-150%-100%-50%0%med -51.19%Dec 24Apr 25Jul 25Oct 25Feb 26May 26Sep 26
ANVS Free Cash Flow Yield by year
PeriodFree Cash Flow Yield
Sep 26-103.14%
Sep 26-83.1%
Aug 26-67.16%
Aug 26-63.47%
Aug 26-62.44%
Aug 26-50.68%
Jul 26-54.44%
Jul 26-57.39%
Jul 26-54.76%
Jul 26-51.22%
Jul 26-49.37%
Jun 26-55.39%
Jun 26-54.44%
Jun 26-53.53%
Jun 26-50.41%
May 26-49.62%
May 26-42.72%
May 26-46.25%
May 26-45.29%
May 26-51.63%
Apr 26-59.34%
Apr 26-55.22%
Apr 26-64.94%
Apr 26-45.29%
Mar 26-50.86%
Mar 26-39.71%
Mar 26-40.97%
Mar 26-50.96%
Feb 26-47.35%
Feb 26-51.16%
Feb 26-53.54%
Feb 26-50.96%
Jan 26-47%
Jan 26-42.16%
Jan 26-43.91%
Jan 26-34.57%
Jan 26-34.76%
Dec 25-35.25%
Dec 25-34.76%
Dec 25-30.72%
Dec 25-27.89%
Nov 25-24.88%
Nov 25-33.48%
Nov 25-54.23%
Nov 25-63.36%
Oct 25-60.34%
Oct 25-61.81%
Oct 25-64%
Oct 25-74.54%
Oct 25-57.08%
Sep 25-64.32%
Sep 25-54.62%
Sep 25-51.09%
Sep 25-55.33%
Aug 25-54.85%
Aug 25-53.47%
Aug 25-46.25%
Aug 25-51.66%
Aug 25-52.48%
Jul 25-45.58%
Jul 25-49.71%
Jul 25-48.61%
Jul 25-55.82%
Jun 25-64.26%
Jun 25-50.66%
Jun 25-46.88%
Jun 25-41.04%
May 25-56.05%
May 25-66.53%
May 25-73.59%
May 25-103.73%
May 25-98.58%
Apr 25-101.09%
Apr 25-130.09%
Apr 25-122.09%
Apr 25-121.16%
Mar 25-96.19%
Mar 25-90.69%
Mar 25-103.54%
Mar 25-101.75%
Feb 25-96.75%
Feb 25-83.12%
Feb 25-64.85%
Feb 25-60.22%
Jan 25-36.36%
Jan 25-35.99%
Jan 25-35.34%
Jan 25-36.21%
Jan 25-32.85%
Dec 24-33.6%
Dec 24-40.52%
Dec 24-33.34%
Dec 24-29.51%
Nov 24-26.39%
Nov 24-26.62%
Nov 24-25.88%
Nov 24-21.7%
Nov 24-28.35%
Oct 24-26.11%
Oct 24-27.98%
EV/EBITDA
255075100125med 67.47Apr 20May 20May 20Jun 20Jul 20Jul 20
ANVS EV/EBITDA by year
PeriodEV/EBITDA
Jul 20114.78
Jul 20119.98
Jul 20117.7
Jul 2061.16
Jun 2073.51
Jun 2077.41
Jun 2067.66
Jun 2094.3
May 2065.7
May 2071.23
May 2037.44
May 2036.46
May 2065.57
Apr 2068.84
Apr 2067.29
Apr 2055.75
Apr 2054.72
Mar 2062.99
Price to Book
05101520med 3.78Nov 24Feb 25Jun 25Sep 25Jan 26Apr 26Aug 26
ANVS Price to Book by year
PeriodPrice to Book
Aug 2616.75
Jul 2615.59
Jul 2614.79
Jul 2615.5
Jul 2616.57
Jul 2617.19
Jun 2615.32
Jun 2615.59
Jun 2615.86
Jun 2616.84
May 2617.1
May 2619.87
May 2618.35
May 263.36
May 262.94
Apr 262.56
Apr 262.75
Apr 262.34
Apr 263.36
Mar 262.99
Mar 263.83
Mar 263.71
Mar 263.73
Feb 264.01
Feb 263.71
Feb 263.55
Feb 263.73
Jan 264.04
Jan 264.5
Jan 264.32
Jan 265.49
Jan 265.46
Dec 255.39
Dec 255.46
Dec 256.18
Dec 256.81
Nov 257.63
Nov 255.67
Nov 253.5
Nov 252.13
Oct 252.23
Oct 252.18
Oct 252.1
Oct 251.81
Oct 252.36
Sep 252.09
Sep 252.47
Sep 252.64
Sep 252.43
Aug 252.46
Aug 252.52
Aug 252.91
Aug 251.85
Aug 251.82
Jul 252.09
Jul 251.92
Jul 251.96
Jul 251.71
Jun 251.49
Jun 251.88
Jun 252.04
Jun 252.33
May 251.7
May 251.43
May 251.3
May 252.27
May 252.39
Apr 252.33
Apr 251.81
Apr 251.93
Apr 251.94
Mar 252.45
Mar 252.59
Mar 253.14
Mar 253.2
Feb 253.36
Feb 253.91
Feb 255.02
Feb 255.4
Jan 258.95
Jan 259.04
Jan 259.2
Jan 258.98
Jan 259.9
Dec 249.68
Dec 248.03
Dec 249.75
Dec 2411.02
Nov 2412.33
Nov 2412.22
Nov 2412.57
Nov 2414.99
Mar 2416.11
Mar 2415.31
Mar 2412.3
Mar 2412.14
Mar 2412.01
Feb 2413.45
Feb 2414.12
Feb 2414.82
Annovis Bio, Inc.
ANVS
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News: ANVS

Annovis Bio (ANVS) Loses 26.5% in 4 Weeks, Here's Why a Trend Reversal May be Around the Corner

zacks.com · 8 Sep 2026

Annovis Bio (ANVS) Loses 26.5% in 4 Weeks, Here's Why a Trend Reversal May be Around the Corner

Annovis Bio (ANVS) has become technically an oversold stock now, which implies exhaustion of the heavy selling pressure on it. This, combined with strong agreement among Wall Street analysts in revising earnings estimates higher, indicates a potential trend reversal for the stock in the near term.

Annovis Bio Targets March 2027 Alzheimer's Readout, Prepares Rolling NDA

marketbeat.com · 2 Sep 2026

Annovis Bio Targets March 2027 Alzheimer's Readout, Prepares Rolling NDA

Annovis Bio NYSE: ANVS said it expects to report top-line results from the six-month portion of its pivotal Phase III Alzheimer's disease trial in March 2027, while preparing a rolling new drug application, or NDA, that management said could begin in May if the study meets its efficacy requirements.

Annovis to Host Corporate Update Webinar on September 2, 2026

globenewswire.com · 25 Aug 2026

Annovis to Host Corporate Update Webinar on September 2, 2026

MALVERN, Pa., Aug. 25, 2026 (GLOBE NEWSWIRE) -- Annovis Bio, Inc. (NYSE: ANVS) (“Annovis” or the “Company”), a Phase 3 clinical-stage biotechnology company developing the investigational oral therapy, buntanetap, for neurodegenerative diseases such as Alzheimer's disease (AD) and Parkinson's disease (PD), today announced it will host a corporate update webinar followed by a live Q&A session.

Annovis Provides Corporate Updates and Second Quarter 2026 Financial Results

globenewswire.com · 14 Aug 2026

Annovis Provides Corporate Updates and Second Quarter 2026 Financial Results

MALVERN, Pa., Aug. 14, 2026 (GLOBE NEWSWIRE) -- Annovis Bio, Inc. (NYSE: ANVS) (“Annovis” or the “Company”), a Phase 3 clinical-stage biotechnology company developing the investigational oral therapy, buntanetap, for neurodegenerative diseases such as Alzheimer's disease (AD) and Parkinson's disease (PD), today provided business updates and reported financial results for the second quarter ended June 30, 2026.

Annovis Reaches Full Enrollment in Pivotal Phase 3 Trial of Buntanetap for Early Alzheimer's Disease

globenewswire.com · 7 Jul 2026

Annovis Reaches Full Enrollment in Pivotal Phase 3 Trial of Buntanetap for Early Alzheimer's Disease

Pivotal Phase 3 trial enrolls 850 patients, exceeding original projections Study completion on track: symptomatic data readout - Q1 2027, disease-modifying data readout - Q1 2028 Company positions for two NDA submissions following each readout MALVERN, Pa., July 07, 2026 (GLOBE NEWSWIRE) -- Annovis Bio, Inc. (NYSE: ANVS) (“Annovis” or the “Company”), a Phase 3 clinical-stage biotechnology company developing the investigational oral therapy, buntanetap, for neurodegenerative diseases such as Alzheimer's disease (AD) and Parkinson's disease (PD), today announced full enrollment of its pivotal Phase 3 trial (NCT06709014) evaluating buntanetap in patients with early AD.

Annovis Appoints Cheng Fang, Ph.D., as Chief Scientific Officer

globenewswire.com · 1 Jul 2026

Annovis Appoints Cheng Fang, Ph.D., as Chief Scientific Officer

MALVERN, Pa., July 01, 2026 (GLOBE NEWSWIRE) -- Annovis Bio, Inc. (NYSE: ANVS) (“Annovis” or the “Company”), a Phase 3 clinical-stage biotechnology company developing the investigational oral therapy, buntanetap, for neurodegenerative diseases such as Alzheimer's disease (AD) and Parkinson's disease (PD), today announced the promotion of Cheng Fang, Ph.D., to Chief Scientific Officer.

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