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Annexon, Inc.

$3.95 -$0.74 (-15.84%)
NASDAQ · 14 Sep 2026 13:55 UTC
Previous Close
$3.94
Day Range
$3.93$4
Year Range
$2.32$7.18
Market Cap
646.69M
AVG Volume
3.25M
Trailing/Forward PE
-3.41/-
PEG ratio
0.65
Dividend Yield
-
Next Earnings Date
2026-11-09
Primary Exchange
NASDAQUS
Net Income (USD)
-300M-200M-100M020182019202020212022202320242025
ANNX Net Income (USD) by year
PeriodNet Income (USD)
2025-206.69M
2024-138.2M
2023-134.24M
2022-141.95M
2021-130.32M
2020-63.41M
2019-37.18M
2018-18.48M
Operating Income (USD)
-300M-200M-100M020182019202020212022202320242025
ANNX Operating Income (USD) by year
PeriodOperating Income (USD)
2025-216.41M
2024-154.07M
2023-143.72M
2022-145.6M
2021-130.71M
2020-63.47M
2019-32.52M
2018-19.15M
EBITDA (USD)
-300M-200M-100M020182019202020212022202320242025
ANNX EBITDA (USD) by year
PeriodEBITDA (USD)
2025-204.05M
2024-135.95M
2023-132.09M
2022-139.84M
2021-128.32M
2020-62.8M
2019-32.02M
2018-18.66M
Cash Flows (USD)
-200M-150M-100M-50M020182019202020212022202320242025
ANNX Cash Flows (USD) by year
PeriodCash Flows (USD)
2025-186.49M
2024-118.02M
2023-121.33M
2022-122.83M
2021-107.79M
2020-53.55M
2019-28.62M
2018-17.21M
EPS (USD)
-60-40-20020182019202020212022202320242025
ANNX EPS (USD) by year
PeriodEPS (USD)
2025-1.36
2024-1.02
2023-1.74
2022-2.82
2021-3.4
2020-2.49
2019-2.84
2018-46.25
Expenses (USD)
0100M200M300MR&DSG&ACapex20182019202020212022202320242025
ANNX Expenses (USD) by year
PeriodExpenses (USD)
2025216.54M
2024150.85M
2023143.5M
2022152.12M
2021132.37M
202063.93M
201932.78M
201819.16M
Cash & Debt (USD)
0100M200M300M400MCashLong Term Debt20182019202020212022202320242025
ANNX Cash & Debt (USD) by year
PeriodCash & Debt (USD)
2025238.34M
2024312.02M
2023259.72M
2022242.66M
2021242.72M
2020351.21M
201943.93M
201844.17M
Debt ratios
00.250.50.75120212022202320242025
ANNX Debt ratios by year
PeriodDebt ratios
20250.35
20240.53
20230.49
20220.58
20210.86
Return on Capital
-100%-75%-50%-25%0%20182019202020212022202320242025
ANNX Return on Capital by year
PeriodReturn on Capital
2025-97.66%
2024-47.15%
2023-53.58%
2022-61.4%
2021-56.2%
2020-18.42%
2019-85.42%
2018-48.79%
Shares Outstanding
050M100M150M200M20182019202020212022202320242025
ANNX Shares Outstanding by year
PeriodShares Outstanding
2025155.11M
2024147.81M
202378.22M
202272.37M
202138.48M
202038.16M
201913.12M
2018432K
Book Value Per Share (USD)
025507510020182019202020212022202320242025
ANNX Book Value Per Share (USD) by year
PeriodBook Value Per Share (USD)
20251.36
20241.98
20233.2
20223.19
20216.03
20209.02
20193.32
201887.69
Total Assets (USD)
0100M200M300M400M20182019202020212022202320242025
ANNX Total Assets (USD) by year
PeriodTotal Assets (USD)
2025277.57M
2024350.07M
2023297.67M
2022285.1M
2021287.04M
2020355.95M
201949.9M
201848.15M
Employee Count
0255075100202020212022202320242025
ANNX Employee Count by year
PeriodEmployee Count
202596
2024100
202371
202280
202161
202048
Free Cash Flow Yield
-60%-40%-20%0%med -23.17%Dec 24Apr 25Jul 25Oct 25Feb 26May 26Sep 26
ANNX Free Cash Flow Yield by year
PeriodFree Cash Flow Yield
Sep 26-24.4%
Sep 26-19.74%
Aug 26-19.34%
Aug 26-18.96%
Aug 26-18.17%
Aug 26-17.43%
Jul 26-18.49%
Jul 26-18.07%
Jul 26-16.26%
Jul 26-16.26%
Jul 26-17.27%
Jun 26-17.21%
Jun 26-19.25%
Jun 26-20.02%
Jun 26-17.83%
May 26-17.4%
May 26-17.76%
May 26-18.1%
May 26-16.58%
May 26-20.91%
Apr 26-20.45%
Apr 26-18.38%
Apr 26-20.55%
Apr 26-21.86%
Mar 26-23.68%
Mar 26-23.17%
Mar 26-20.92%
Mar 26-22.95%
Feb 26-21.15%
Feb 26-24.17%
Feb 26-24.22%
Feb 26-20.67%
Jan 26-18.98%
Jan 26-17.47%
Jan 26-19.51%
Jan 26-22.56%
Jan 26-25.25%
Dec 25-23.17%
Dec 25-22.9%
Dec 25-23.83%
Dec 25-25.69%
Nov 25-26.31%
Nov 25-27.73%
Nov 25-43.7%
Nov 25-36.58%
Oct 25-33.34%
Oct 25-32.82%
Oct 25-33.45%
Oct 25-33.98%
Oct 25-33.03%
Sep 25-31.26%
Sep 25-36.84%
Sep 25-43.53%
Sep 25-48.55%
Aug 25-51.14%
Aug 25-45.61%
Aug 25-43.18%
Aug 25-40.02%
Aug 25-38.55%
Jul 25-37.63%
Jul 25-40.71%
Jul 25-36.61%
Jul 25-32.68%
Jun 25-39.19%
Jun 25-39.68%
Jun 25-37.93%
Jun 25-36.33%
May 25-46.3%
May 25-44.76%
May 25-46.99%
May 25-49.9%
May 25-40.53%
Apr 25-42.47%
Apr 25-54.69%
Apr 25-53.59%
Apr 25-47.25%
Mar 25-35.49%
Mar 25-33.27%
Mar 25-30.71%
Mar 25-28.93%
Feb 25-28.55%
Feb 25-26.83%
Feb 25-24.55%
Feb 25-21.91%
Jan 25-19.63%
Jan 25-18.25%
Jan 25-17.95%
Jan 25-15.61%
Jan 25-13.93%
Dec 24-14.52%
Dec 24-14.41%
Dec 24-16.98%
Dec 24-14.78%
Nov 24-13.99%
Nov 24-14.67%
Nov 24-12.32%
Nov 24-10.82%
Nov 24-10.74%
Oct 24-10.57%
Oct 24-10.46%
Price to Book
02468med 2.45Dec 24Apr 25Jul 25Oct 25Feb 26May 26Sep 26
ANNX Price to Book by year
PeriodPrice to Book
Sep 264.26
Sep 265.26
Aug 265.37
Aug 265.48
Aug 265.71
Aug 265.14
Jul 264.84
Jul 264.96
Jul 265.51
Jul 265.51
Jul 265.18
Jun 265.2
Jun 264.65
Jun 264.47
Jun 265.02
May 265.15
May 265.04
May 264.95
May 265.4
May 264.21
Apr 264.31
Apr 264.79
Apr 264.29
Apr 264.03
Mar 264.62
Mar 264.72
Mar 265.23
Mar 264.77
Feb 265.17
Feb 264.53
Feb 264.52
Feb 265.29
Jan 265.76
Jan 266.26
Jan 265.61
Jan 264.85
Jan 264.33
Dec 254.72
Dec 254.78
Dec 254.59
Dec 254.26
Nov 254.16
Nov 253.94
Nov 252.5
Nov 252.15
Oct 252.36
Oct 252.39
Oct 252.35
Oct 252.31
Oct 252.38
Sep 252.51
Sep 252.13
Sep 251.8
Sep 251.62
Aug 251.54
Aug 251.72
Aug 251.82
Aug 251.43
Aug 251.49
Jul 251.52
Jul 251.41
Jul 251.57
Jul 251.76
Jun 251.46
Jun 251.45
Jun 251.51
Jun 251.58
May 251.24
May 251.28
May 251.22
May 250.81
May 250.99
Apr 250.95
Apr 250.74
Apr 250.75
Apr 250.85
Mar 251.13
Mar 251.21
Mar 251.31
Mar 251.39
Feb 251.11
Feb 251.19
Feb 251.3
Feb 251.45
Jan 251.62
Jan 251.74
Jan 251.77
Jan 252.04
Jan 252.28
Dec 242.19
Dec 242.21
Dec 241.87
Dec 242.15
Nov 242.27
Nov 242.17
Nov 242.58
Nov 242.61
Nov 242.62
Oct 242.67
Oct 242.7
Annexon, Inc.
ANNX
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News: ANNX

Annexon to Participate in Upcoming September Investor Conferences

globenewswire.com · 2 Sep 2026

Annexon to Participate in Upcoming September Investor Conferences

BRISBANE, Calif., Sept. 02, 2026 (GLOBE NEWSWIRE) -- Annexon, Inc. (Nasdaq: ANNX), a biopharmaceutical company advancing the next generation platform of targeted immunotherapies aimed at neuroinflammatory diseases that impact nearly 10 million people worldwide, today announced that Douglas Love, Esq., president & chief executive officer, will participate in fireside chats during the following September investor conferences:

Annexon Reports Inducement Grants to New Employees Under Nasdaq Listing Rule 5635(c)(4)

globenewswire.com · 17 Aug 2026

Annexon Reports Inducement Grants to New Employees Under Nasdaq Listing Rule 5635(c)(4)

BRISBANE, Calif., Aug. 17, 2026 (GLOBE NEWSWIRE) -- Annexon, Inc. (Nasdaq: ANNX), a biopharmaceutical company advancing the next generation platform of targeted immunotherapies aimed at neuroinflammatory diseases that impact nearly 10 million people worldwide, today announced that it has granted inducement to three new non-executive employees under the terms of the 2022 Employment Inducement Award Plan. The equity awards were approved on August 10, 2026, in accordance with Nasdaq Listing Rule 5635(c)(4).

Annexon, Inc. (ANNX) Q2 2026 Earnings Call Transcript

seekingalpha.com · 12 Aug 2026

Annexon, Inc. (ANNX) Q2 2026 Earnings Call Transcript

Annexon, Inc. (ANNX) Q2 2026 Earnings Call Transcript

Annexon Q2 Earnings Call Highlights

marketbeat.com · 12 Aug 2026

Annexon Q2 Earnings Call Highlights

Annexon NASDAQ: ANNX said it expanded its pivotal ARCHER II trial of vonaprument in geographic atrophy, adding an independent 24-month dual primary endpoint alongside the study's existing 15-month primary endpoint. The company said it remains confident in a planned fourth-quarter assessment of the 15-month endpoint while seeking to capture longer-term efficacy data for a potential product label.

Annexon Reports Second Quarter 2026 Financial Results, Business Updates and Key Anticipated Milestones

globenewswire.com · 12 Aug 2026

Annexon Reports Second Quarter 2026 Financial Results, Business Updates and Key Anticipated Milestones

Rapid, Positive Clinical Outcomes in GBS FORWARD Study Reinforce Consistency and Reproducibility of Tanruprubart Treatment Effect Demonstrated in Phase 3 and Real-World Evidence Studies; BLA Submission Expected in Q4 2026

Annexon Expands Vonaprument Phase 3 Program in Geographic Atrophy with Addition of Month 24 Dual Primary Endpoint Complementing Month 15 Primary Endpoint and Launch of Open-Label Extension Study

globenewswire.com · 12 Aug 2026

Annexon Expands Vonaprument Phase 3 Program in Geographic Atrophy with Addition of Month 24 Dual Primary Endpoint Complementing Month 15 Primary Endpoint and Launch of Open-Label Extension Study

BRISBANE, Calif., Aug. 12, 2026 (GLOBE NEWSWIRE) -- Annexon, Inc. (Nasdaq: ANNX), a biopharmaceutical company advancing the next generation platform of targeted immunotherapies for multiple neuroinflammatory diseases that impact nearly 10 million people worldwide, today announced the addition of a Month 24 dual primary endpoint to complement the current Month 15 primary endpoint in its Phase 3 ARCHER II trial, and launch of an open-label extension (OLE) study of vonaprument for the treatment of dry age-related macular degeneration (AMD) with geographic atrophy (GA). With a dual primary endpoint strategy, ARCHER II can achieve success in protecting against vision loss at either Month 15 or 24, which are independent efficacy timepoints.

Annexon Reports First U.S. and European Patient Cohort of GBS FORWARD Study Demonstrated Rapid, Positive Clinical Responses in All Tanruprubart Treated Patients Within One Week

globenewswire.com · 6 Aug 2026

Annexon Reports First U.S. and European Patient Cohort of GBS FORWARD Study Demonstrated Rapid, Positive Clinical Responses in All Tanruprubart Treated Patients Within One Week

Early Outcomes Reinforce the Consistency and Reproducibility of Tanruprubart Treatment Effect Previously Demonstrated in Phase 3 and Real-World Evidence Studies

Annexon Secures Strategic Credit Facility for up to $200 Million from Oxford Finance

globenewswire.com · 30 Jul 2026

Annexon Secures Strategic Credit Facility for up to $200 Million from Oxford Finance

Expands Financial Capacity as Vonaprument and Tanruprubart Programs Advance Toward Registration Expands Financial Capacity as Vonaprument and Tanruprubart Programs Advance Toward Registration

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