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AC Immune S.A.

$2.66 -$0.70 (-20.83%)
NASDAQ · 14 Sep 2026 20:00 UTC
Previous Close
$2.76
Day Range
$2.66$2.73
Year Range
$2.1$4
Market Cap
270.72M
AVG Volume
250.05K
Trailing/Forward PE
-5.05/13.33
PEG ratio
0.03
Dividend Yield
-
Next Earnings Date
2026-11-03
Primary Exchange
NASDAQUS
Revenue (CHF)
050M100M150M2016201720182019202020212022202320242025
ACIU Revenue (CHF) by year
PeriodRevenue (CHF)
20253.57M
202427.31M
202314.8M
20223.94M
20210
202015.43M
2019110.82M
20187.19M
201720.25M
201623.21M
Net Income (CHF)
-100M-50M050M2016201720182019202020212022202320242025
ACIU Net Income (CHF) by year
PeriodNet Income (CHF)
2025-70.45M
2024-50.92M
2023-54.23M
2022-70.76M
2021-73M
2020-61.92M
201945.44M
2018-50.95M
2017-26.41M
2016-7.1M
Operating Income (CHF)
-100M-50M050M2016201720182019202020212022202320242025
ACIU Operating Income (CHF) by year
PeriodOperating Income (CHF)
2025-69.33M
2024-52.38M
2023-53.62M
2022-70.85M
2021-79.01M
2020-29.89M
201944.54M
2018-49.55M
2017-22.54M
2016-10.46M
EBITDA (CHF)
-100M-50M050M2016201720182019202020212022202320242025
ACIU EBITDA (CHF) by year
PeriodEBITDA (CHF)
2025-68.07M
2024-48.62M
2023-51.83M
2022-68.31M
2021-70.01M
2020-59.72M
201944.4M
2018-49.69M
2017-26.72M
2016-7.62M
Cash Flows (CHF)
-100M-50M050M100M2016201720182019202020212022202320242025
ACIU Cash Flows (CHF) by year
PeriodCash Flows (CHF)
2025-70.1M
202465.27M
2023-61.21M
2022-74.81M
2021-68.32M
2020-61.22M
201953.34M
2018-45.94M
2017-23.9M
2016-6.54M
EPS (CHF)
-1-0.500.512016201720182019202020212022202320242025
ACIU EPS (CHF) by year
PeriodEPS (CHF)
2025-0.7
2024-0.51
2023-0.65
2022-0.87
2021-0.98
2020-0.86
20190.65
2018-0.81
2017-0.47
2016-0.14
Expenses (CHF)
020M40M60M80MR&DSG&ACapex2016201720182019202020212022202320242025
ACIU Expenses (CHF) by year
PeriodExpenses (CHF)
202568.91M
202474.58M
202365.98M
202277.35M
202175.8M
202079.75M
201968.38M
201853.7M
201740.74M
201630.99M
Cash & Debt (CHF)
0100M200M300MCashLong Term DebtShort Term Debt2016201720182019202020212022202320242025
ACIU Cash & Debt (CHF) by year
PeriodCash & Debt (CHF)
202591.52M
2024165.49M
2023103.05M
2022122.59M
2021198.22M
2020225.89M
2019288.59M
2018186.46M
2017124.38M
2016152.21M
Debt ratios
0246820182019202020212022202320242025
ACIU Debt ratios by year
PeriodDebt ratios
20250.37
20240.67
20230.4
20220.78
20211.45
20202.44
20197.21
20182.9
Margins
-800%-600%-400%-200%0%200%2015201620172018201920202022202320242025
ACIU Margins by year
PeriodMargins
2025100%
2024100%
2023100%
2022-650.22%
2020-285.5%
201954.49%
2018-515.44%
2017-61.16%
2016-11.03%
201556.39%
Return on Capital
-200%-150%-100%-50%0%50%2016201720182019202020212022202320242025
ACIU Return on Capital by year
PeriodReturn on Capital
2025-156.78%
2024-45.35%
2023-33.76%
2022-41.87%
2021-31.47%
2020-28.74%
201916.68%
2018-28.68%
2017-22.6%
2016-4.99%
Shares Outstanding
050M100M150M2016201720182019202020212022202320242025
ACIU Shares Outstanding by year
PeriodShares Outstanding
2025101.17M
2024110.06M
202384.14M
202283.59M
202179.27M
202071.94M
201971.86M
201867.92M
201757.27M
201656.41M
Book Value Per Share (CHF)
012342016201720182019202020212022202320242025
ACIU Book Value Per Share (CHF) by year
PeriodBook Value Per Share (CHF)
20250.44
20241.02
20231.91
20222.02
20212.93
20203
20193.79
20182.62
20172.04
20162.52
Total Assets (CHF)
0100M200M300M2016201720182019202020212022202320242025
ACIU Total Assets (CHF) by year
PeriodTotal Assets (CHF)
2025154.43M
2024230.91M
2023182.81M
2022185.94M
2021261.44M
2020238.74M
2019299.25M
2018196.56M
2017132.01M
2016156.1M
Employee Count
0501001502002016201720182019202020212022202320242025
ACIU Employee Count by year
PeriodEmployee Count
2025122
2024172
2023161
2022156
2021143
2020149
2019132
2018104
201786
201667
PE Ratio
68101214med 11.87Jan 20Feb 20Feb 20Mar 20Apr 20May 20
ACIU PE Ratio by year
PeriodPE Ratio
May 2010.36
Apr 2012.15
Apr 2012
Apr 2010.66
Apr 2011.59
Mar 208.64
Mar 206.68
Mar 206.35
Mar 209.32
Feb 209.49
Feb 2011.77
Feb 2011.97
Feb 2013.27
Jan 2012.8
Jan 2012
Jan 2012.73
Jan 2012.94
Jan 2012.07
Free Cash Flow Yield
-50%-25%0%25%50%med -16.72%Dec 24Apr 25Jul 25Nov 25Feb 26Jun 26Sep 26
ACIU Free Cash Flow Yield by year
PeriodFree Cash Flow Yield
Sep 26-16.32%
Sep 26-15.72%
Sep 26-15.29%
Aug 26-16.52%
Aug 26-15.25%
Aug 26-17.51%
Aug 26-18.59%
Jul 26-29.21%
Jul 26-28.3%
Jul 26-29.08%
Jul 26-26.74%
Jul 26-25.59%
Jun 26-24.92%
Jun 26-26.75%
Jun 26-28.05%
Jun 26-28.84%
May 26-33.38%
May 26-31.21%
May 26-31.58%
May 26-31.24%
May 26-29.77%
Apr 26-31.12%
Apr 26-29.46%
Apr 26-26.8%
Apr 26-31.43%
Mar 26-32.15%
Mar 26-30.88%
Mar 26-29.01%
Mar 26-22.26%
Feb 26-21.38%
Feb 26-24.65%
Feb 26-20.98%
Feb 26-19.77%
Jan 26-19.53%
Jan 26-16.68%
Jan 26-17.09%
Jan 26-17.63%
Jan 26-18.09%
Dec 25-19.49%
Dec 25-19.97%
Dec 25-19.21%
Dec 25-21.38%
Nov 25-20.04%
Nov 25-19.86%
Nov 25-18.45%
Nov 25-18.13%
Oct 25-15.95%
Oct 25-16.77%
Oct 25-18.85%
Oct 25-15.29%
Oct 25-13.67%
Sep 25-19.14%
Sep 25-22.25%
Sep 25-22.42%
Sep 25-23.83%
Aug 25-26.55%
Aug 25-25.17%
Aug 25-25.24%
Aug 25-25.08%
Aug 2526.5%
Jul 2523.38%
Jul 2527.21%
Jul 2527.79%
Jul 2527.45%
Jun 2528.13%
Jun 2529.37%
Jun 2528.56%
Jun 2526.92%
May 2532.11%
May 2532.54%
May 2531.53%
May 2532.33%
May 2531.77%
Apr 2543.72%
Apr 2548.92%
Apr 2546.7%
Apr 2541.56%
Mar 2534.04%
Mar 2532.01%
Mar 2529.29%
Mar 2520.35%
Feb 2518.83%
Feb 2518.15%
Feb 2517.52%
Feb 2517.64%
Jan 2517.22%
Jan 2517.47%
Jan 2517.61%
Jan 2517.32%
Jan 2515.95%
Dec 2417.53%
Dec 2418.03%
Dec 2416.4%
Dec 2415.6%
Nov 2414.41%
Nov 2414.28%
Nov 2415.23%
Nov 2415.4%
Nov 2416.87%
Oct 2416.65%
Price to Sales
020406080med 9.66Dec 24Apr 25Jul 25Nov 25Feb 26Jun 26Sep 26
ACIU Price to Sales by year
PeriodPrice to Sales
Sep 2612.24
Sep 2612.7
Sep 2613.05
Aug 2612.08
Aug 2613.09
Aug 2611.4
Aug 2610.74
Jul 2647.09
Jul 2648.61
Jul 2647.3
Jul 2651.45
Jul 2653.75
Jun 2655.2
Jun 2651.42
Jun 2649.04
Jun 2647.7
May 2658.77
May 2662.87
May 2662.12
May 2662.81
May 2665.91
Apr 2663.05
Apr 2666.6
Apr 2673.21
Apr 2662.42
Mar 2661.02
Mar 2663.53
Mar 2667.62
Mar 2649.02
Feb 2651.03
Feb 2644.27
Feb 2652
Feb 2655.19
Jan 2655.87
Jan 2665.43
Jan 2663.83
Jan 2661.9
Jan 2660.31
Dec 2555.98
Dec 2554.63
Dec 2556.81
Dec 2551.04
Nov 2554.44
Nov 2554.94
Nov 2559.14
Nov 2560.17
Oct 259.46
Oct 258.99
Oct 258
Oct 259.87
Oct 2511.03
Sep 257.88
Sep 256.78
Sep 256.73
Sep 256.33
Aug 255.68
Aug 255.99
Aug 255.97
Aug 256.01
Aug 256.04
Jul 256.85
Jul 255.88
Jul 255.76
Jul 255.83
Jun 255.69
Jun 255.45
Jun 255.61
Jun 255.95
May 254.99
May 254.92
May 255.08
May 254.95
May 255.04
Apr 255.47
Apr 254.88
Apr 255.12
Apr 255.75
Mar 257.02
Mar 257.47
Mar 258.16
Mar 255.16
Feb 255.58
Feb 255.79
Feb 256
Feb 255.96
Jan 256.1
Jan 256.02
Jan 255.97
Jan 256.07
Jan 256.59
Dec 245.99
Dec 245.83
Dec 246.41
Dec 246.74
Nov 247.29
Nov 247.36
Nov 246.9
Nov 246.82
Nov 2416.76
Oct 2416.98
EV/EBITDA
02468med 5.91Jan 20Feb 20Feb 20Mar 20Apr 20May 20
ACIU EV/EBITDA by year
PeriodEV/EBITDA
May 204.17
Apr 206
Apr 205.85
Apr 204.48
Apr 205.43
Mar 202.75
Mar 200.73
Mar 200.39
Mar 203.45
Feb 203.63
Feb 205.98
Feb 206.18
Feb 207.53
Jan 207.04
Jan 206.22
Jan 206.97
Jan 207.19
Jan 206.29
Price/Operating Cashflow
02.557.51012.5med 5.72Feb 20Apr 20Oct 24Jan 25Mar 25May 25Aug 25
ACIU Price/Operating Cashflow by year
PeriodPrice/Operating Cashflow
Aug 253.72
Jul 254.21
Jul 253.62
Jul 253.54
Jul 253.59
Jun 253.5
Jun 253.35
Jun 253.45
Jun 253.66
May 253.07
May 253.03
May 253.12
May 253.05
May 253.1
Apr 252.27
Apr 252.03
Apr 252.12
Apr 252.39
Mar 252.91
Mar 253.1
Mar 253.38
Mar 254.84
Feb 255.23
Feb 255.43
Feb 255.62
Feb 255.58
Jan 255.72
Jan 255.64
Jan 255.59
Jan 255.69
Jan 256.18
Dec 245.62
Dec 245.46
Dec 246.01
Dec 246.32
Nov 246.84
Nov 246.9
Nov 246.47
Nov 246.4
Nov 245.83
Oct 245.9
Oct 246.04
Oct 246.36
Oct 246.48
Sep 247.04
Sep 247
Sep 246.03
Sep 245.63
Aug 246.13
May 208.53
Apr 2010
Apr 209.88
Apr 208.77
Apr 209.54
Mar 207.72
Mar 205.97
Mar 205.67
Mar 208.32
Feb 208.48
Feb 2010.51
Feb 2010.69
Feb 2011.85
Jan 2011.43
Jan 2010.72
Jan 2011.38
Jan 2011.56
Jan 2010.78
Price to Book
02468med 3.1Dec 24Apr 25Jul 25Nov 25Feb 26Jun 26Sep 26
ACIU Price to Book by year
PeriodPrice to Book
Sep 266.09
Sep 266.32
Sep 266.5
Aug 266.02
Aug 266.52
Aug 265.68
Aug 265.35
Jul 265.53
Jul 265.71
Jul 265.55
Jul 266.04
Jul 266.31
Jun 266.48
Jun 266.04
Jun 265.76
Jun 265.6
May 264.67
May 265
May 264.94
May 264.99
May 265.24
Apr 265.01
Apr 265.3
Apr 265.82
Apr 264.96
Mar 264.85
Mar 265.05
Mar 265.38
Mar 263.43
Feb 263.57
Feb 263.1
Feb 263.64
Feb 263.86
Jan 263.91
Jan 264.58
Jan 264.47
Jan 264.33
Jan 264.22
Dec 253.92
Dec 253.82
Dec 253.98
Dec 253.57
Nov 253.81
Nov 253.85
Nov 254.14
Nov 254.21
Oct 253.66
Oct 253.48
Oct 253.1
Oct 253.82
Oct 254.27
Sep 253.05
Sep 252.62
Sep 252.6
Sep 252.45
Aug 252.2
Aug 252.32
Aug 252.31
Aug 252.33
Aug 251.8
Jul 252.04
Jul 251.76
Jul 251.72
Jul 251.74
Jun 251.7
Jun 251.63
Jun 251.67
Jun 251.78
May 251.49
May 251.47
May 251.52
May 251.48
May 251.5
Apr 251.33
Apr 251.19
Apr 251.24
Apr 251.4
Mar 251.71
Mar 251.82
Mar 251.98
Mar 251.63
Feb 251.76
Feb 251.82
Feb 251.89
Feb 251.88
Jan 251.92
Jan 251.89
Jan 251.88
Jan 251.91
Jan 252.07
Dec 241.89
Dec 241.83
Dec 242.02
Dec 242.12
Nov 242.3
Nov 242.32
Nov 242.17
Nov 242.15
Nov 242.1
Oct 242.13
AC Immune S.A.
ACIU
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News: ACIU

AC Immune Announces Positive Preliminary Phase 1 Data for NLRP3 Inhibitor ACI-19764

globenewswire.com · 20 Aug 2026

AC Immune Announces Positive Preliminary Phase 1 Data for NLRP3 Inhibitor ACI-19764

AC Immune announced positive interim Phase 1 results from a first-in-human clinical study evaluating ACI-19764, an NLRP3 inhibitor targeting inflammation.

AC Immune (ACIU) Beats Q2 Earnings and Revenue Estimates

zacks.com · 5 Aug 2026

AC Immune (ACIU) Beats Q2 Earnings and Revenue Estimates

AC Immune (ACIU) came out with quarterly earnings of $0.03 per share, beating the Zacks Consensus Estimate of a loss of $0.22 per share. This compares to a loss of $0.25 per share a year ago.

AC Immune First Half 2026 Financial and Corporate Update

globenewswire.com · 5 Aug 2026

AC Immune First Half 2026 Financial and Corporate Update

AC Immune First Half 2026 Financial and Corporate Update Focused portfolio of wholly-owned programs approach near-term clinical catalysts as partnered programs generate milestone payments Key advances across pipeline, with further near-term clinical results anticipated for H2 2026 Phase 2 VacSYn trial of ACI-7104 in Parkinson's disease supported by a $4 million grant from The Vijay and Marie Goradia Charitable Foundation Morphomer small molecule program targeting intracellular Tau progresses with Lilly Initiation of Alzheimer's disease AD4 cohort in ABATE trial triggered $12 million milestone payment from Takeda Cash resources of CHF 75.4 million as of June 30, 2026, provide funding into Q4 2027 Lausanne, Switzerland, August 5, 2026 -- AC Immune SA (NASDAQ: ACIU), a clinical-stage biopharmaceutical company developing targeted therapeutics for neurodegenerative diseases, today provided a corporate and financial update for the half-year ended June 30, 2026. Martin Zügel, MD, interim CEO of AC Immune and Chair of the Board of Directors, commented: “AC Immune is moving towards key clinical milestones in two of our wholly-owned programs, a growing focus for AC Immune.

AC Immune to Showcase Neurodegenerative Disease Pipeline with Three Presentations at AAIC® 2026

globenewswire.com · 7 Jul 2026

AC Immune to Showcase Neurodegenerative Disease Pipeline with Three Presentations at AAIC® 2026

AC Immune to Showcase Neurodegenerative Disease Pipeline with Three Presentations at AAIC ® 2026 Lausanne, Switzerland, July 7, 2026 -- AC Immune SA (NASDAQ: ACIU), a clinical-stage biopharmaceutical company pioneering precision therapeutics for neurodegenerative diseases, today announces three presentations at the Alzheimer's Association International Conference® 2026, taking place July 12-15 in London, UK. Across these AAIC presentations, we are showing how AC Immune's Morphomer®-based small molecule approach has generated differentiated therapeutic and imaging assets.

AC Immune Reports Interim 12-Month Data from Phase 1b/2 ABATE Trial of ACI-24 in Prodromal Alzheimer's Disease

globenewswire.com · 30 Jun 2026

AC Immune Reports Interim 12-Month Data from Phase 1b/2 ABATE Trial of ACI-24 in Prodromal Alzheimer's Disease

AC Immune Reports Interim 12-Month Data from Phase 1b/2 ABATE Trial of ACI-24 in Prodromal Alzheimer's Disease ACI-24 anti-Abeta active immunotherapy generally safe and well tolerated in first three Alzheimer's disease (AD) cohorts in ABATE Anti-Abeta antibody dose-response demonstrated with antibodies detected at all dose levels in cohorts AD1-3 Ongoing AD4 cohort includes additional adjuvant designed to enhance ACI-24 responses Lausanne, Switzerland, June 30, 2026 -- AC Immune SA (NASDAQ: ACIU), a clinical-stage biopharmaceutical company pioneering precision therapeutics for neurodegenerative diseases, today announced interim data from the first three cohorts (AD1, AD2 & AD3) of 74 patients with prodromal Alzheimer's disease (AD) in the Phase 1b/2 ABATE trial following 12 months of treatment with ACI-24 anti-amyloid beta (Abeta) active immunotherapy. In the trial to date, ACI-24 has been generally safe and well tolerated, with no evidence of amyloid-related imaging abnormalities-edema (ARIA-E).

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