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Santhera Pharmaceuticals Holding AG

$19.79 +$6.44 (+48.24%)

OTC · 14 Sep 2026 20:00 UTC

Previous Close

$19.79

Day Range

$19.79$23.25

Year Range

$12.28$23.25

Market Cap

293.51M

AVG Volume

259

Trailing/Forward PE

-4.07/119.38

PEG ratio

0.04

Dividend Yield

Next Earnings Date

2026-09-21

Primary Exchange

Other OTC

Revenue (CHF)

SPHDF Revenue (CHF) by quarter
Period	Revenue (CHF)
25 Q4	53.2M
25 Q2	24.01M
24 Q4	25M
24 Q2	14.11M
23 Q4	99.44M
23 Q2	3.94M
22 Q4	1.22M
22 Q2	6.25M
21 Q4	-6.09M
21 Q2	4.49M

Net Income (CHF)

SPHDF Net Income (CHF) by quarter
Period	Net Income (CHF)
25 Q4	-10.41M
25 Q2	-38.83M
24 Q4	-26.71M
24 Q2	-15.26M
23 Q4	78.12M
23 Q2	-23.34M
22 Q4	-41.35M
22 Q2	-29.72M
21 Q4	-35.01M
21 Q2	-20.52M

Operating Income (CHF)

SPHDF Operating Income (CHF) by quarter
Period	Operating Income (CHF)
25 Q4	-2.37M
25 Q2	-35.44M
24 Q4	-15.59M
24 Q2	-17.74M
23 Q4	70.85M
23 Q2	-20.34M
22 Q4	-20.32M
22 Q2	-25.55M
21 Q4	-37.69M
21 Q2	-19.45M

EBITDA (CHF)

SPHDF EBITDA (CHF) by quarter
Period	EBITDA (CHF)
25 Q4	480.23K
25 Q2	-32.61M
24 Q4	-1.4M
24 Q2	-14.97M
23 Q4	92.75M
23 Q2	-13.58M
22 Q4	-27.82M
22 Q2	-18.96M
21 Q4	-27.56M
21 Q2	-7.01M

Cash Flows (CHF)

SPHDF Cash Flows (CHF) by quarter
Period	Cash Flows (CHF)
25 Q4	-14.22M
25 Q2	-20.67M
24 Q4	-20.32M
24 Q2	-15.36M
23 Q4	62.54M
23 Q2	-15.36M
22 Q4	-21.84M
22 Q2	-11.96M
21 Q4	-18.72M
21 Q2	-18.65M

EPS (CHF)

SPHDF EPS (CHF) by quarter
Period	EPS (CHF)
25 Q4	-0.78
25 Q2	-3.04
24 Q4	-2.34
24 Q2	-1.35
23 Q4	7
23 Q2	-2.09
22 Q4	-6.43
22 Q2	-5.24
21 Q4	-7.06
21 Q2	-9.22

Expenses (CHF)

SPHDF Expenses (CHF) by quarter
Period	Expenses (CHF)
25 Q4	25.36M
25 Q2	27.41M
24 Q4	30.01M
24 Q2	26.77M
23 Q4	27.37M
23 Q2	4.9M
22 Q4	23.47M
22 Q2	29.62M
21 Q4	29.53M
21 Q2	21.58M

Cash & Debt (CHF)

SPHDF Cash & Debt (CHF) by quarter
Period	Cash & Debt (CHF)
25 Q4	22.45M
25 Q2	18.4M
24 Q4	40.92M
24 Q2	16.49M
23 Q4	30.37M
23 Q2	1.67M
22 Q4	1.35M
22 Q2	12.7M
21 Q4	21.21M
21 Q2	7.99M

Debt ratios

SPHDF Debt ratios by quarter
Period	Debt ratios
25 Q4	-1.55
25 Q2	0.52
24 Q4	0
24 Q2	0.27
23 Q4	-0.27
23 Q2	-0.45
22 Q4	-0.53
22 Q2	-0.35
21 Q4	-0.25
21 Q2	-0.8

Margins

SPHDF Margins by quarter
Period	Margins
25 Q4	43.11%
25 Q2	-33.77%
24 Q4	57.37%
24 Q2	63.05%
23 Q4	98.35%
23 Q2	43.29%
22 Q4	-65.82%
22 Q2	65.25%
21 Q4	133.61%
21 Q2	46.46%

Return on Capital

SPHDF Return on Capital by quarter
Period	Return on Capital
25 Q4	88.05%
25 Q2	1515.1%
24 Q4	-96.44%
24 Q2	-31.76%
23 Q4	130.32%
23 Q2	54.57%
22 Q4	94.66%
22 Q2	214.69%
21 Q4	-2636.07%
21 Q2	-245.65%

Shares Outstanding

SPHDF Shares Outstanding by quarter
Period	Shares Outstanding
25 Q4	13.39M
25 Q2	12.78M
24 Q4	11.4M
24 Q2	11.34M
23 Q4	11.16M
23 Q2	11.16M
22 Q4	6.44M
22 Q2	5.67M
21 Q4	4.96M
21 Q2	2.22M

Book Value Per Share (CHF)

SPHDF Book Value Per Share (CHF) by quarter
Period	Book Value Per Share (CHF)
25 Q4	-0.88
25 Q2	-0.2
24 Q4	2.43
24 Q2	4.24
23 Q4	5.37
23 Q2	-3.83
22 Q4	-6.79
22 Q2	-2.44
21 Q4	0.27
21 Q2	3.76

Total Assets (CHF)

SPHDF Total Assets (CHF) by quarter
Period	Total Assets (CHF)
25 Q4	148.16M
25 Q2	130.77M
24 Q4	152.49M
24 Q2	108.25M
23 Q4	109.63M
23 Q2	63.08M
22 Q4	63.73M
22 Q2	79.78M
21 Q4	91.12M
21 Q2	80.22M

PE Ratio

SPHDF PE Ratio by quarter
Period	PE Ratio
Sep 25	13.06
Sep 25	13.02
Sep 25	13.03
Sep 25	13.06
Aug 25	13.1
Aug 25	13.11
Aug 25	13.2
Aug 25	13.22
Aug 25	13.15
Jul 25	10.43
Jul 25	10.52
Jul 25	10.45
Jul 25	10.42
Jun 25	10.48
Jun 25	10.73
Jun 25	10.64
Jun 25	10.78
May 25	10.79
May 25	12.81
May 25	13.06
May 25	12.97
May 25	12.89
Apr 25	12.91
Apr 25	11.99
Apr 25	12.32
Apr 25	13.01

Free Cash Flow Yield

SPHDF Free Cash Flow Yield by quarter
Period	Free Cash Flow Yield
Sep 26	-32.62%
Sep 26	-32.62%
Sep 26	-27.98%
Aug 26	-28.01%
Aug 26	-28.29%
Aug 26	-27.89%
Aug 26	-28.06%
Jul 26	-28.09%
Jul 26	-27.71%
Jul 26	-28.09%
Jul 26	-28.06%
Jul 26	-28.21%
Jun 26	-28.01%
Jun 26	-28.19%
Jun 26	-28.45%
Jun 26	-28.49%
May 26	-29.04%
May 26	-28.88%
May 26	-28.82%
May 26	-29.22%
May 26	-29.01%
Apr 26	-30.61%
Apr 26	-30.65%
Apr 26	-34.1%
Apr 26	-33.66%
Mar 26	3.1%
Mar 26	3.44%
Mar 26	3.02%
Mar 26	3.13%
Feb 26	2.98%
Feb 26	2.96%
Feb 26	3.88%
Feb 26	3.84%
Jan 26	4.01%
Jan 26	3.97%
Jan 26	4.52%
Jan 26	4.53%
Jan 26	4.58%
Dec 25	4.6%
Dec 25	4.56%
Dec 25	4.56%
Dec 25	4.51%
Nov 25	4.52%
Nov 25	4.49%
Nov 25	4.58%
Nov 25	4.91%
Oct 25	4.91%
Oct 25	4.97%
Oct 25	4.98%
Oct 25	4.55%
Oct 25	4.58%
Sep 25	6.88%
Sep 25	6.9%
Sep 25	6.89%
Sep 25	6.88%
Aug 25	6.85%
Aug 25	6.85%
Aug 25	6.8%
Aug 25	6.79%
Aug 25	6.83%
Jul 25	8.61%
Jul 25	8.54%
Jul 25	8.6%
Jul 25	8.62%
Jun 25	8.57%
Jun 25	8.37%
Jun 25	8.44%
Jun 25	8.33%
May 25	8.33%
May 25	7.01%
May 25	6.88%
May 25	6.93%
May 25	6.97%
Apr 25	6.96%
Apr 25	7.49%
Apr 25	7.29%
Apr 25	6.9%
Mar 25	5.89%
Mar 25	6.07%
Mar 25	6.23%
Mar 25	10.63%
Feb 25	10.36%
Feb 25	10.43%
Feb 25	10.4%
Feb 25	10.29%
Jan 25	10.26%
Jan 25	10.34%
Jan 25	10.23%
Jan 25	10.21%
Jan 25	10.3%
Dec 24	10.37%
Dec 24	10.48%
Dec 24	10.48%
Dec 24	10.65%
Nov 24	8.55%
Nov 24	8.43%
Nov 24	8.48%
Nov 24	8.6%
Nov 24	8.66%
Oct 24	8.69%

Price to Sales

SPHDF Price to Sales by quarter
Period	Price to Sales
Sep 26	1.86
Sep 26	1.86
Sep 26	2.17
Aug 26	2.17
Aug 26	2.14
Aug 26	2.18
Aug 26	2.16
Jul 26	2.16
Jul 26	2.19
Jul 26	2.16
Jul 26	2.16
Jul 26	2.15
Jun 26	2.17
Jun 26	2.15
Jun 26	2.13
Jun 26	2.13
May 26	2.09
May 26	2.1
May 26	2.11
May 26	2.08
May 26	2.09
Apr 26	1.98
Apr 26	1.98
Apr 26	1.78
Apr 26	1.8
Mar 26	1.23
Mar 26	1.11
Mar 26	1.26
Mar 26	1.22
Feb 26	1.28
Feb 26	1.29
Feb 26	0.98
Feb 26	0.99
Jan 26	0.95
Jan 26	0.96
Jan 26	0.84
Jan 26	0.84
Jan 26	0.83
Dec 25	0.83
Dec 25	0.83
Dec 25	0.83
Dec 25	0.84
Nov 25	0.84
Nov 25	0.85
Nov 25	0.83
Nov 25	0.78
Oct 25	0.78
Oct 25	0.77
Oct 25	0.77
Oct 25	0.84
Oct 25	0.83
Sep 25	1.17
Sep 25	1.17
Sep 25	1.17
Sep 25	1.17
Aug 25	1.18
Aug 25	1.18
Aug 25	1.19
Aug 25	1.19
Aug 25	1.18
Jul 25	0.94
Jul 25	0.95
Jul 25	0.94
Jul 25	0.94
Jun 25	0.94
Jun 25	0.96
Jun 25	0.96
Jun 25	0.97
May 25	0.97
May 25	1.15
May 25	1.17
May 25	1.17
May 25	1.16
Apr 25	1.16
Apr 25	1.08
Apr 25	1.11
Apr 25	1.17
Mar 25	1.43
Mar 25	1.39
Mar 25	1.35
Mar 25	0.79
Feb 25	0.81
Feb 25	0.81
Feb 25	0.81
Feb 25	0.82
Jan 25	0.82
Jan 25	0.81
Jan 25	0.82
Jan 25	0.82
Jan 25	0.82
Dec 24	0.81
Dec 24	0.8
Dec 24	0.8
Dec 24	0.79
Nov 24	0.98
Nov 24	1
Nov 24	0.99
Nov 24	0.98
Nov 24	0.97
Oct 24	0.97

EV/EBITDA

SPHDF EV/EBITDA by quarter
Period	EV/EBITDA
Mar 26	5.09
Mar 26	4.64
Mar 26	5.21
Mar 26	5.04
Feb 26	5.26
Feb 26	5.31
Feb 26	4.17
Feb 26	4.21
Jan 26	4.05
Jan 26	4.08
Jan 26	3.65
Jan 26	3.64
Jan 26	3.61
Dec 25	3.6
Dec 25	3.62
Dec 25	3.62
Dec 25	3.66
Nov 25	3.65
Nov 25	3.67
Nov 25	3.61
Nov 25	3.4
Oct 25	3.4
Oct 25	3.37
Oct 25	3.36
Oct 25	3.63
Oct 25	3.61
Sep 25	2.67
Sep 25	2.66
Sep 25	2.66
Sep 25	2.67
Aug 25	2.68
Aug 25	2.68
Aug 25	2.7
Aug 25	2.7
Aug 25	2.69
Jul 25	2.13
Jul 25	2.15
Jul 25	2.13
Jul 25	2.13
Jun 25	2.14
Jun 25	2.19
Jun 25	2.17
Jun 25	2.2
May 25	2.2
May 25	2.62
May 25	2.67
May 25	2.65
May 25	2.63
Apr 25	2.64
Apr 25	2.45
Apr 25	2.52
Apr 25	2.66
Mar 25	4.93
Mar 25	4.79
Mar 25	4.68
Mar 25	2.85
Feb 25	2.92
Feb 25	2.9
Feb 25	2.91
Feb 25	2.94
Jan 25	2.94
Jan 25	2.93
Jan 25	2.95
Jan 25	2.96
Jan 25	2.93
Dec 24	2.92
Dec 24	2.89
Dec 24	2.89
Dec 24	2.85
Nov 24	3.48
Nov 24	3.53
Nov 24	3.51
Nov 24	3.46
Nov 24	3.44
Oct 24	3.43
Oct 24	3.42
Oct 24	3.39
Oct 24	3.4
Sep 24	3.11
Sep 24	3.15
Sep 24	3.15
Sep 24	3.12
Aug 24	3.15
Aug 24	3.14
Aug 24	3.21
Aug 24	3.21
Aug 24	3.18
Jul 24	3.29
Jul 24	3.31
Jul 24	3.33
Jul 24	3.34
Jun 24	3.35
Jun 24	3.33
Jun 24	3.31
Jun 24	3.34
May 24	3.36
May 24	3.41
May 24	3.39
May 24	3.38
May 24	3.37

Price/Operating Cashflow

SPHDF Price/Operating Cashflow by quarter
Period	Price/Operating Cashflow
Mar 26	30.74
Mar 26	27.69
Mar 26	31.55
Mar 26	30.38
Feb 26	31.93
Feb 26	32.21
Feb 26	24.54
Feb 26	24.8
Jan 26	23.73
Jan 26	23.96
Jan 26	21.04
Jan 26	21.01
Jan 26	20.77
Dec 25	20.7
Dec 25	20.86
Dec 25	20.87
Dec 25	21.09
Nov 25	21.07
Nov 25	21.19
Nov 25	20.8
Nov 25	19.39
Oct 25	19.39
Oct 25	19.17
Oct 25	19.12
Oct 25	20.9
Oct 25	20.8
Sep 25	14.24
Sep 25	14.2
Sep 25	14.21
Sep 25	14.25
Aug 25	14.29
Aug 25	14.3
Aug 25	14.39
Aug 25	14.42
Aug 25	14.34
Jul 25	11.37
Jul 25	11.47
Jul 25	11.39
Jul 25	11.37
Jun 25	11.42
Jun 25	11.7
Jun 25	11.6
Jun 25	11.76
May 25	11.77
May 25	13.97
May 25	14.25
May 25	14.14
May 25	14.06
Apr 25	14.08
Apr 25	13.07
Apr 25	13.44
Apr 25	14.19
Mar 25	12.03
Mar 25	11.66
Mar 25	11.37
Mar 25	6.66
Feb 25	6.83
Feb 25	6.79
Feb 25	6.81
Feb 25	6.88
Jan 25	6.9
Jan 25	6.85
Jan 25	6.92
Jan 25	6.93
Jan 25	6.87
Dec 24	6.82
Dec 24	6.76
Dec 24	6.75
Dec 24	6.65
Nov 24	8.28
Nov 24	8.4
Nov 24	8.35
Nov 24	8.23
Nov 24	8.18
Oct 24	8.15
Oct 24	8.13
Oct 24	8.06
Oct 24	8.07
Sep 24	6.29
Sep 24	6.36
Sep 24	6.36
Sep 24	6.31
Aug 24	6.37
Aug 24	6.35
Aug 24	6.48
Aug 24	6.48
Aug 24	6.42
Jul 24	6.62
Jul 24	6.66
Jul 24	6.7
Jul 24	6.71
Jun 24	6.73
Jun 24	6.7
Jun 24	6.67
Jun 24	6.72
May 24	6.76
May 24	6.85
May 24	6.8
May 24	6.79
May 24	6.78

Price to Book

SPHDF Price to Book by quarter
Period	Price to Book
Sep 25	6.04
Sep 25	6.02
Sep 25	6.02
Sep 25	6.04
Aug 25	6.06
Aug 25	6.06
Aug 25	6.1
Aug 25	6.11
Aug 25	6.08
Jul 25	4.82
Jul 25	4.86
Jul 25	4.83
Jul 25	4.82
Jun 25	4.84
Jun 25	4.96
Jun 25	4.92
Jun 25	4.99
May 25	4.99
May 25	5.92
May 25	6.04
May 25	6
May 25	5.96
Apr 25	5.97
Apr 25	5.54
Apr 25	5.7
Apr 25	6.02
Mar 25	3.53
Mar 25	3.42
Mar 25	3.34
Mar 25	1.95
Feb 25	2
Feb 25	1.99
Feb 25	2
Feb 25	2.02
Jan 25	2.02
Jan 25	2.01
Jan 25	2.03
Jan 25	2.03
Jan 25	2.02
Dec 24	2
Dec 24	1.98
Dec 24	1.98
Dec 24	1.95
Nov 24	2.43
Nov 24	2.47
Nov 24	2.45
Nov 24	2.42
Nov 24	2.4
Oct 24	2.39
Oct 24	2.38
Oct 24	2.36
Oct 24	2.37
Sep 24	1.83
Sep 24	1.85
Sep 24	1.85
Sep 24	1.84
Aug 24	1.85
Aug 24	1.85
Aug 24	1.88
Aug 24	1.88
Aug 24	1.87
Jul 24	1.92
Jul 24	1.94
Jul 24	1.95
Jul 24	1.95
Jun 24	1.96
Jun 24	1.95
Jun 24	1.94
Jun 24	1.95
May 24	1.96
May 24	1.99
May 24	1.98
May 24	1.97
May 24	1.97
Apr 24	1.99
Apr 24	1.98
Apr 24	1.99
Apr 24	1.96
Sep 22	5163.58
Sep 22	5076.39
Sep 22	5054.23
Sep 22	5161.47
Aug 22	5085.13
Aug 22	5047.59
Aug 22	4954.98
Aug 22	5062.91
Jul 22	5006.89
Jul 22	5060.23
Jul 22	5138.26
Jul 22	5139.68
Jul 22	5049.96
Jun 22	5045.22
Jun 22	5104.4
Jun 22	5198.17
Jun 22	5067.44
May 22	5038.96
May 22	5130.67
May 22	5271.88
May 22	5204.07
Apr 22	5124.36

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News: SPHDF

proactiveinvestors.co.uk · 18 Aug 2026

Santhera nears cash break-even as AGAMREE gains traction, Edison says

Santhera Pharmaceuticals (SIX:SANN, OTC:SPHDF, FRA:S3F0), the Swiss rare-disease drugmaker, is closing in on a financial turning point, according to research house Edison. In a QuickView note published on Tuesday, analysts Jyoti Prakash and Arron Aatkar said the company was on track to reach cash flow break-even in the third quarter, completing its shift into a self-funded business.

AI Analysis

Santhera Pharmaceuticals Holding AG

Video analysis: SPHDF

News: SPHDF

Santhera nears cash break-even as AGAMREE gains traction, Edison says

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