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Alnylam Pharmaceuticals, Inc.

$248.68 -$151.49 (-37.86%)
NASDAQ · 11 Sep 2026 20:00 UTC
Previous Close
$247.51
Day Range
$246.01$254.08
Year Range
$197.81$495.55
Market Cap
33.28B
AVG Volume
1.59M
Trailing/Forward PE
40.77/24.68
PEG ratio
0.8
Dividend Yield
-
Next Earnings Date
2026-10-29
Primary Exchange
NASDAQUS
Revenue (USD)
0500M1B1.5B24 Q124 Q224 Q324 Q425 Q125 Q225 Q325 Q426 Q126 Q2
ALNY Revenue (USD) by quarter
PeriodRevenue (USD)
26 Q21.29B
26 Q11.17B
25 Q41.1B
25 Q31.25B
25 Q2773.69M
25 Q1594.19M
24 Q4593.17M
24 Q3500.92M
24 Q2659.83M
24 Q1494.33M
Net Income (USD)
-200M-100M0100M200M300M24 Q124 Q224 Q324 Q425 Q125 Q225 Q325 Q426 Q126 Q2
ALNY Net Income (USD) by quarter
PeriodNet Income (USD)
26 Q2164.49M
26 Q1205.99M
25 Q4186.42M
25 Q3251.08M
25 Q2-66.28M
25 Q1-57.48M
24 Q4-83.76M
24 Q3-111.57M
24 Q2-16.89M
24 Q1-65.94M
Operating Income (USD)
-200M0200M400M24 Q124 Q224 Q324 Q425 Q125 Q225 Q325 Q426 Q126 Q2
ALNY Operating Income (USD) by quarter
PeriodOperating Income (USD)
26 Q2231.44M
26 Q1268.64M
25 Q4131.72M
25 Q3367.98M
25 Q2-16.2M
25 Q118.08M
24 Q4-105.16M
24 Q3-76.91M
24 Q248.61M
24 Q1-43.44M
EBITDA (USD)
-200M0200M400M24 Q124 Q224 Q324 Q425 Q125 Q225 Q325 Q426 Q126 Q2
ALNY EBITDA (USD) by quarter
PeriodEBITDA (USD)
26 Q2244.72M
26 Q1304.49M
25 Q4303.98M
25 Q3297.17M
25 Q218.83M
25 Q111.46M
24 Q4-140.91M
24 Q3-60.3M
24 Q237.09M
24 Q1-14.82M
Cash Flows (USD)
-200M0200M400M24 Q124 Q224 Q324 Q425 Q125 Q225 Q325 Q426 Q126 Q2
ALNY Cash Flows (USD) by quarter
PeriodCash Flows (USD)
26 Q240.64M
26 Q148.67M
25 Q4140.26M
25 Q3312.97M
25 Q2139.44M
25 Q1-127.28M
24 Q4-103.76M
24 Q339.52M
24 Q2116.14M
24 Q1-94.49M
EPS (USD)
-101224 Q124 Q224 Q324 Q425 Q125 Q225 Q325 Q426 Q126 Q2
ALNY EPS (USD) by quarter
PeriodEPS (USD)
26 Q21.2
26 Q11.51
25 Q41.37
25 Q31.84
25 Q2-0.51
25 Q1-0.44
24 Q4-0.65
24 Q3-0.87
24 Q2-0.13
24 Q1-0.52
Expenses (USD)
0200M400M600M800MR&DSG&ACapex24 Q124 Q224 Q324 Q425 Q125 Q225 Q325 Q426 Q126 Q2
ALNY Expenses (USD) by quarter
PeriodExpenses (USD)
26 Q2795.74M
26 Q1709.25M
25 Q4720.88M
25 Q3693.03M
25 Q2661.23M
25 Q1514.04M
24 Q4604.6M
24 Q3496.11M
24 Q2550.56M
24 Q1484.76M
Cash & Debt (USD)
01B2B3B4BCashLong Term Debt24 Q124 Q224 Q324 Q425 Q125 Q225 Q325 Q426 Q126 Q2
ALNY Cash & Debt (USD) by quarter
PeriodCash & Debt (USD)
26 Q23.31B
26 Q13.01B
25 Q42.91B
25 Q32.72B
25 Q22.86B
25 Q12.63B
24 Q42.69B
24 Q32.78B
24 Q22.62B
24 Q12.37B
Debt ratios
-20-100102024 Q124 Q224 Q324 Q425 Q125 Q225 Q325 Q426 Q126 Q2
ALNY Debt ratios by quarter
PeriodDebt ratios
26 Q2-1.77
26 Q1-1.88
25 Q4-2.58
25 Q3-7.59
25 Q29.13
25 Q18.72
24 Q47.82
24 Q311.29
24 Q2-10.62
24 Q17.45
Margins
0%25%50%75%100%24 Q124 Q224 Q324 Q425 Q125 Q225 Q325 Q426 Q126 Q2
ALNY Margins by quarter
PeriodMargins
26 Q276.9%
26 Q181.91%
25 Q475.6%
25 Q384.21%
25 Q281.52%
25 Q188.04%
24 Q482.67%
24 Q382.85%
24 Q289.59%
24 Q186.65%
Return on Capital
-500%-250%0%250%500%750%24 Q124 Q224 Q324 Q425 Q125 Q225 Q325 Q426 Q126 Q2
ALNY Return on Capital by quarter
PeriodReturn on Capital
26 Q212.15%
26 Q119.16%
25 Q423.62%
25 Q3107.35%
25 Q2-26.45%
25 Q1-49.79%
24 Q4-124.86%
24 Q3-344.84%
24 Q2550.67%
24 Q130.07%
Shares Outstanding
050M100M150M24 Q124 Q224 Q324 Q425 Q125 Q225 Q325 Q426 Q126 Q2
ALNY Shares Outstanding by quarter
PeriodShares Outstanding
26 Q2133.24M
26 Q1132.89M
25 Q4132.23M
25 Q3131.45M
25 Q2129.68M
25 Q1129.68M
24 Q4128.59M
24 Q3128.59M
24 Q2126.73M
24 Q1126.14M
Book Value Per Share (USD)
-505101524 Q124 Q224 Q324 Q425 Q125 Q225 Q325 Q426 Q126 Q2
ALNY Book Value Per Share (USD) by quarter
PeriodBook Value Per Share (USD)
26 Q210.16
26 Q18.09
25 Q45.97
25 Q31.78
25 Q21.93
25 Q10.89
24 Q40.52
24 Q30.25
24 Q2-0.02
24 Q1-1.74
Total Assets (USD)
02B4B6B24 Q124 Q224 Q324 Q425 Q125 Q225 Q325 Q426 Q126 Q2
ALNY Total Assets (USD) by quarter
PeriodTotal Assets (USD)
26 Q25.56B
26 Q15.13B
25 Q44.97B
25 Q34.85B
25 Q24.57B
25 Q14.21B
24 Q44.24B
24 Q34.21B
24 Q24.01B
24 Q13.82B
Employee Count
01K2K3K2016201720182019202020212022202320242025
ALNY Employee Count by quarter
PeriodEmployee Count
20252.5K
20242.23K
20232.1K
20222K
20211.67K
20201.45K
20191.32K
20181.06K
2017749
2016514
PE Ratio
050010001500med 131.83Nov 25Jan 26Feb 26Apr 26Jun 26Jul 26Sep 26
ALNY PE Ratio by quarter
PeriodPE Ratio
Sep 2641.01
Sep 2643.88
Aug 2639.1
Aug 2638.95
Aug 2637.71
Aug 2636.15
Jul 2633.89
Jul 2662.57
Jul 2661.58
Jul 2668.78
Jul 2672.01
Jun 2667.08
Jun 2664.02
Jun 2665.12
Jun 2669.77
May 2669.53
May 2668.48
May 2666.07
May 2667.93
May 2668.17
Apr 26128.77
Apr 26130.51
Apr 26135.76
Apr 26134.38
Mar 26133.75
Mar 26131.57
Mar 26132.09
Mar 26135.15
Feb 26140.31
Feb 26141.69
Feb 26132.51
Feb 26990.14
Jan 261020.02
Jan 261080.12
Jan 261084.01
Jan 261201.75
Jan 261207.42
Dec 251208.68
Dec 251207.6
Dec 251199.51
Dec 251382.27
Nov 251361.48
Nov 251316.67
Nov 251355.23
Nov 251335.74
Oct 251375.99
Free Cash Flow Yield
-1%0%1%2%med 0.05%Dec 24Apr 25Jul 25Oct 25Feb 26May 26Sep 26
ALNY Free Cash Flow Yield by quarter
PeriodFree Cash Flow Yield
Sep 261.64%
Sep 261.53%
Aug 261.72%
Aug 261.72%
Aug 261.78%
Aug 261.86%
Jul 261.98%
Jul 261.78%
Jul 261.8%
Jul 261.62%
Jul 261.54%
Jun 261.66%
Jun 261.74%
Jun 261.71%
Jun 261.59%
May 261.6%
May 261.62%
May 261.68%
May 261.64%
May 261.63%
Apr 261.15%
Apr 261.14%
Apr 261.09%
Apr 261.1%
Mar 261.11%
Mar 261.13%
Mar 261.12%
Mar 261.1%
Feb 261.06%
Feb 261.05%
Feb 261.12%
Feb 260.51%
Jan 260.5%
Jan 260.47%
Jan 260.47%
Jan 260.42%
Jan 260.42%
Dec 250.42%
Dec 250.42%
Dec 250.42%
Dec 250.37%
Nov 250.37%
Nov 250.39%
Nov 250.37%
Nov 250.38%
Oct 250.37%
Oct 25-0.09%
Oct 25-0.08%
Oct 25-0.09%
Oct 25-0.09%
Sep 25-0.09%
Sep 25-0.09%
Sep 25-0.09%
Sep 25-0.09%
Aug 25-0.09%
Aug 25-0.09%
Aug 25-0.09%
Aug 25-0.09%
Aug 25-0.1%
Jul 25-0.18%
Jul 25-0.18%
Jul 25-0.18%
Jul 25-0.18%
Jun 25-0.18%
Jun 25-0.19%
Jun 25-0.19%
Jun 25-0.19%
May 25-0.19%
May 25-0.2%
May 25-0.2%
May 25-0.23%
May 25-0.22%
Apr 25-0.13%
Apr 25-0.14%
Apr 25-0.14%
Apr 25-0.14%
Mar 25-0.12%
Mar 25-0.12%
Mar 25-0.14%
Mar 25-0.14%
Feb 25-0.13%
Feb 25-0.13%
Feb 25-0.13%
Feb 250.05%
Jan 250.05%
Jan 250.04%
Jan 250.05%
Jan 250.05%
Jan 250.05%
Dec 240.05%
Dec 240.05%
Dec 240.05%
Dec 240.05%
Nov 240.05%
Nov 240.05%
Nov 240.05%
Nov 240.05%
Nov 240.05%
Oct 240.88%
Oct 240.85%
Price to Sales
51015202530med 14.87Dec 24Apr 25Jul 25Oct 25Feb 26May 26Sep 26
ALNY Price to Sales by quarter
PeriodPrice to Sales
Sep 266.9
Sep 267.38
Aug 266.58
Aug 266.55
Aug 266.34
Aug 266.08
Jul 265.7
Jul 268.42
Jul 268.29
Jul 269.26
Jul 269.7
Jun 269.03
Jun 268.62
Jun 268.77
Jun 269.39
May 269.36
May 269.22
May 268.9
May 269.15
May 269.18
Apr 2610.88
Apr 2611.03
Apr 2611.47
Apr 2611.35
Mar 2611.3
Mar 2611.11
Mar 2611.16
Mar 2611.42
Feb 2611.85
Feb 2611.97
Feb 2611.19
Feb 2613.44
Jan 2613.84
Jan 2614.66
Jan 2614.71
Jan 2616.31
Jan 2616.39
Dec 2516.4
Dec 2516.39
Dec 2516.28
Dec 2518.76
Nov 2518.48
Nov 2517.87
Nov 2518.39
Nov 2518.13
Oct 2518.67
Oct 2524.41
Oct 2525.37
Oct 2524.25
Oct 2524.04
Sep 2523.51
Sep 2523.89
Sep 2524.54
Sep 2523.81
Aug 2523.52
Aug 2523.93
Aug 2523.64
Aug 2523.12
Aug 2521.16
Jul 2518.16
Jul 2517.7
Jul 2517.39
Jul 2518.33
Jun 2517.83
Jun 2517.1
Jun 2517.01
Jun 2516.61
May 2516.82
May 2516.01
May 2515.76
May 2513.87
May 2514.33
Apr 2514.39
Apr 2513.42
Apr 2513.6
Apr 2513.48
Mar 2515.35
Mar 2516.21
Mar 2513.83
Mar 2513.99
Feb 2514.11
Feb 2514.33
Feb 2514.67
Feb 2516.95
Jan 2516.65
Jan 2517.11
Jan 2515.12
Jan 2514.61
Jan 2514.38
Dec 2414.61
Dec 2415.07
Dec 2415.07
Dec 2415.73
Nov 2415.53
Nov 2415.03
Nov 2414.46
Nov 2417.03
Nov 2416.81
Oct 2415.4
Oct 2416
EV/EBITDA
0100200300400med 67.14Aug 24Oct 25Jan 26Mar 26May 26Jul 26Sep 26
ALNY EV/EBITDA by quarter
PeriodEV/EBITDA
Sep 2627.03
Sep 2629.05
Aug 2625.69
Aug 2625.59
Aug 2624.71
Aug 2623.62
Jul 2622.03
Jul 2637.19
Jul 2636.57
Jul 2641.07
Jul 2643.08
Jun 2640.01
Jun 2638.1
Jun 2638.78
Jun 2641.69
May 2641.53
May 2640.88
May 2639.38
May 2640.54
May 2640.69
Apr 2661.4
Apr 2662.27
Apr 2664.87
Apr 2664.19
Mar 2663.88
Mar 2662.79
Mar 2663.05
Mar 2664.57
Feb 2667.14
Feb 2667.82
Feb 2663.26
Feb 26223.64
Jan 26230.62
Jan 26244.65
Jan 26245.56
Jan 26273.06
Jan 26274.38
Dec 25274.68
Dec 25274.42
Dec 25272.54
Dec 25315.22
Nov 25310.36
Nov 25299.9
Nov 25308.9
Nov 25304.35
Oct 25313.75
Oct 24279.65
Oct 24290.93
Oct 24279.1
Oct 24262.46
Sep 24269.51
Sep 24268.46
Sep 24259.68
Sep 24240.84
Aug 24257.06
Aug 24267.19
Aug 24262.71
Aug 24264.02
Aug 24266.59
Price/Operating Cashflow
050001000015000med 104.44Apr 24Jul 24Nov 24Oct 25Feb 26May 26Sep 26
ALNY Price/Operating Cashflow by quarter
PeriodPrice/Operating Cashflow
Sep 2652.22
Sep 2655.88
Aug 2649.79
Aug 2649.61
Aug 2648.02
Aug 2646.03
Jul 2643.16
Jul 2650.66
Jul 2649.86
Jul 2655.69
Jul 2658.31
Jun 2654.31
Jun 2651.84
Jun 2652.73
Jun 2656.49
May 2656.29
May 2655.45
May 2653.5
May 2655
May 2655.2
Apr 2677.09
Apr 2678.13
Apr 2681.27
Apr 2680.45
Mar 2680.07
Mar 2678.76
Mar 2679.08
Mar 2680.91
Feb 2684
Feb 2684.82
Feb 2679.33
Feb 26162.25
Jan 26167.14
Jan 26176.99
Jan 26177.63
Jan 26196.92
Jan 26197.85
Dec 25198.06
Dec 25197.88
Dec 25196.56
Dec 25226.5
Nov 25223.1
Nov 25215.75
Nov 25222.07
Nov 25218.88
Oct 25225.47
Feb 25627.98
Jan 25616.88
Jan 25633.82
Jan 25559.95
Jan 25541.1
Jan 25532.69
Dec 24541.08
Dec 24558.06
Dec 24558.06
Dec 24582.66
Nov 24575.41
Nov 24556.81
Nov 24535.6
Nov 24630.8
Nov 24622.79
Oct 2496.98
Oct 24100.75
Oct 2496.79
Oct 2491.24
Sep 2493.59
Sep 2493.24
Sep 2490.31
Sep 2484.01
Aug 2489.43
Aug 2492.82
Aug 2491.32
Aug 2491.76
Aug 2492.62
Jul 24156.64
Jul 24158.63
Jul 24173.76
Jul 24167.43
Jun 24162.08
Jun 24110.52
Jun 24106.98
Jun 24101.9
May 2499
May 2498.55
May 2499.65
May 24100.36
May 24101.6
Apr 24172.83
Apr 24174.16
Apr 24179.09
Apr 24185.19
Mar 24180.24
Mar 24176.69
Mar 24180.02
Mar 24180.68
Mar 24184.05
Feb 24190.13
Feb 24177.28
Feb 2410791.26
Feb 2410983.56
Price to Book
050010001500med 235.64Dec 24Apr 25Jul 25Oct 25Feb 26May 26Sep 26
ALNY Price to Book by quarter
PeriodPrice to Book
Sep 2624.47
Sep 2626.18
Aug 2623.33
Aug 2623.24
Aug 2622.5
Aug 2621.57
Jul 2620.22
Jul 2633.58
Jul 2633.05
Jul 2636.92
Jul 2638.65
Jun 2636.01
Jun 2634.37
Jun 2634.95
Jun 2637.45
May 2637.32
May 2636.76
May 2635.46
May 2636.46
May 2636.59
Apr 2651.2
Apr 2651.89
Apr 2653.97
Apr 2653.43
Mar 2653.18
Mar 2652.31
Mar 2652.51
Mar 2653.73
Feb 2655.78
Feb 2656.33
Feb 2652.68
Feb 26184.42
Jan 26189.99
Jan 26201.18
Jan 26201.91
Jan 26223.84
Jan 26224.89
Dec 25225.13
Dec 25224.93
Dec 25223.42
Dec 25257.46
Nov 25253.59
Nov 25245.24
Nov 25252.43
Nov 25248.79
Oct 25256.29
Oct 25239.82
Oct 25249.25
Oct 25238.28
Oct 25236.15
Sep 25231
Sep 25234.71
Sep 25241.09
Sep 25233.9
Aug 25231.06
Aug 25235.13
Aug 25232.3
Aug 25227.14
Aug 25207.92
Jul 25369.37
Jul 25360.07
Jul 25353.79
Jul 25372.86
Jun 25362.66
Jun 25347.91
Jun 25345.99
Jun 25337.94
May 25342.13
May 25325.73
May 25320.51
May 25282.13
May 25291.39
Apr 25482.17
Apr 25449.59
Apr 25455.74
Apr 25451.85
Mar 25514.57
Mar 25543.09
Mar 25463.39
Mar 25468.68
Feb 25472.95
Feb 25480.31
Feb 25491.55
Feb 251097.71
Jan 251078.31
Jan 251107.92
Jan 25978.79
Jan 25945.84
Jan 25931.14
Dec 24945.8
Dec 24975.49
Dec 24975.49
Dec 241018.5
Nov 241005.82
Nov 24973.31
Nov 24936.23
Nov 241102.64
Nov 241088.65
Oct 22136.58
Oct 22127.41
Alnylam Pharmaceuticals, Inc.
ALNY
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News: ALNY

Arizona State Retirement System Boosts Stock Position in Alnylam Pharmaceuticals, Inc. $ALNY

defenseworld.net · 10 Sep 2026

Arizona State Retirement System Boosts Stock Position in Alnylam Pharmaceuticals, Inc. $ALNY

Arizona State Retirement System grew its stake in shares of Alnylam Pharmaceuticals, Inc. (NASDAQ: ALNY) by 5.9% in the second quarter, according to its most recent filing with the Securities and Exchange Commission. The firm owned 38,025 shares of the biopharmaceutical company's stock after acquiring an additional 2,126 shares during the period. Arizona

Concurrent Investment Advisors LLC Acquires 6,576 Shares of Alnylam Pharmaceuticals, Inc. $ALNY

defenseworld.net · 9 Sep 2026

Concurrent Investment Advisors LLC Acquires 6,576 Shares of Alnylam Pharmaceuticals, Inc. $ALNY

Concurrent Investment Advisors LLC raised its holdings in shares of Alnylam Pharmaceuticals, Inc. (NASDAQ: ALNY) by 695.9% in the undefined quarter, according to its most recent 13F filing with the Securities and Exchange Commission (SEC). The fund owned 7,521 shares of the biopharmaceutical company's stock after purchasing an additional 6,576 shares during the

Alnylam Pharmaceuticals, Inc. (ALNY) Presents at Wells Fargo 21st Annual Healthcare Conference Transcript

seekingalpha.com · 8 Sep 2026

Alnylam Pharmaceuticals, Inc. (ALNY) Presents at Wells Fargo 21st Annual Healthcare Conference Transcript

Alnylam Pharmaceuticals, Inc. (ALNY) Presents at Wells Fargo 21st Annual Healthcare Conference Transcript

Alnylam to Webcast Presentations at Upcoming September Investor Conferences

businesswire.com · 2 Sep 2026

Alnylam to Webcast Presentations at Upcoming September Investor Conferences

CAMBRIDGE, Mass.--(BUSINESS WIRE)--Alnylam Pharmaceuticals, Inc. (Nasdaq: ALNY), the leading RNAi therapeutics company, announced today that management will present company overviews at the following upcoming investor conferences: Wells Fargo 21st Annual Healthcare Conference on Tuesday, September 8, 2026, at 8:45 AM ET in Everett, Massachusetts Morgan Stanley 24th Annual Global Healthcare Conference on Monday, September 14, 2026, at 10:00 AM ET in New York City A live audio webcast of each pre.

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ALNY, BMRN, RARE and BBIO offer rare-disease growth potential through strong products, pipeline catalysts and high unmet medical needs.

Alnylam Pharmaceuticals, Inc. (NASDAQ:ALNY) Receives $386.14 Consensus Target Price from Analysts

defenseworld.net · 31 Aug 2026

Alnylam Pharmaceuticals, Inc. (NASDAQ:ALNY) Receives $386.14 Consensus Target Price from Analysts

Shares of Alnylam Pharmaceuticals, Inc. (NASDAQ: ALNY - Get Free Report) have been given a consensus recommendation of "Moderate Buy" by the twenty-four research firms that are covering the company, MarketBeat.com reports. Five equities research analysts have rated the stock with a hold rating, sixteen have assigned a buy rating and three have issued a strong

Alnylam Presents New Data at ESC Congress 2026 Reinforcing Strength in RNAi-Powered TTR Silencing Across ATTR-CM Patient Populations and Treatment Settings

gurufocus.com · 30 Aug 2026

Alnylam Presents New Data at ESC Congress 2026 Reinforcing Strength in RNAi-Powered TTR Silencing Across ATTR-CM Patient Populations and Treatment Settings

[url="]Alnylam Pharmaceuticals, Inc[/url]. (Nasdaq: ALNY), the leading RNAi therapeutics company, today announced new data at the European Society of Cardiology

Alnylam Presents New Data at ESC Congress 2026 Reinforcing Strength in RNAi-Powered TTR Silencing Across ATTR-CM Patient Populations and Treatment Settings

businesswire.com · 30 Aug 2026

Alnylam Presents New Data at ESC Congress 2026 Reinforcing Strength in RNAi-Powered TTR Silencing Across ATTR-CM Patient Populations and Treatment Settings

CAMBRIDGE, Mass.--(BUSINESS WIRE)--Alnylam Pharmaceuticals, Inc. (Nasdaq: ALNY), the leading RNAi therapeutics company, today announced new data at the European Society of Cardiology (ESC) Congress 2026 demonstrating the strength of RNAi-powered silencing for cardiovascular disease. The findings further reinforce the clinical profile of AMVUTTRA® (vutrisiran) across transthyretin amyloidosis (ATTR) patient populations, treatment settings, and manifestations of disease. Additionally, the data ex.

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